Erythrocyte senescence

Erythrocytes: Physiology and Pathophysiology

Volumn , Issue , 2012, Pages 301-326

  Bosman, Giel J C G M ^a   Willekens, Frans L A ^a   Werre, Jan M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84891693255     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1142/P740     Document Type: Chapter

References (104)

1. Todd C, White RG. Fate of red blood corpuscles when injected into circulation of animal of same species. Proc Royal Soc London Series B: Biol Sci. 1911;84:255-259.
2. Ashby W. The determination of the length of life of transfused blood corpuscles in man. J Exp Med. 1919;29:267-281.
3. Callender ST, Powell EO, Witts CJ. Lifespan of red cell in man. J Pathol Bacteriol. 1945;57:129-139.
4. Dornhorst AC. Interpretation of red cell survival curves. Blood. 1951;6: 1284-1292.
5. Shemin D, Rittenberg D. The lifespan of the human red blood cell. J Biol Chem. 1946;166:627-636.
6. Finch CA, Wolff JA, Rath CE, Fluharty RG. Iron metabolism; erythrocyte iron turnover. J Lab Clin Med. 1949;34:1480-1490.
7. Berlin NI, Berk PO. The biological life of the red blood cell. In: Surgenor DM, editor. The Red Blood Cell. New York: Academic Press; 1975, pp. 957-1019.
8. Berlin NI, Waldmann TA, Weiszman SM. Lifespan of red blood cells. Physiol Rev. 1959;39:577-616.
9. Borun ER, Figueroa WG, Perry SM. The distribution of Fe59 tagged human erythrocytes in centrifuged specimens as a function of cell age. J Clin Invest. 1957;36:676-679.
10. Hoffman JE. On the relationship of certain erythrocyte characteristics to their physiological age. J Cell Comp Physiol. 1958;51:415.
11. Prankerd TA. The ageing of red cells. J Physiol. 1958;143:325-331.
12. Van der Vegt SG, Ruben AM, Werre JM, Palsma DM, Verhoef CW, De Gier J et al. Counterflow centrifugation of red cell populations: a cell age related separation technique. Brit J Haematol. 1985;61:393-403.
13. Mollison PL, Engelfriet CP, Contreras M. The transfusion of red cells. In: Mollison PL, Engelfriet CP, Contreras M. Blood Transfusion in Clinical Medicine. Oxford: Blackwell Scientific; 1987, pp. 95-158.
14. 51Cr labelling. Brit J Haematol. 2002;117:998.
15. Cohen JA, Warringa MG. The fate of P32 labelled diisopropylfluorophosphonate in the human body and its use as a labelling agent in the study of the turnover of blood plasma and red cells. J Clin Invest. 1954;33:459-467.
16. Bratteby LE, Wadman B. Labelling of red blood cells in vitro with small amounts of di-iso-propyl-flurophosphonate (DF32P). Scand J Clin Lab Invest. 1968;21:197-201.
17. Suzuki T, Dale GL. Biotinylated erythrocytes: in vivo survival and in vitro recovery. Blood. 1987;70:791-795.
18. Hoffmann-Fezer G, Maschke H, Zeitler HJ, Gais P, Heger W, Ellwart J et al. Direct in vivo biotinylation of erythrocytes as an assay for red cell survival studies. Ann Hematol. 1991;63:214-217.
19. Hoffmann-Fezer G, Mysliwietz J, Mortlbauer W, Zeitler HJ, Eberle E, Honle U et al. Biotin labeling as an alternative nonradioactive approach to determination of red cell survival. Ann Hematol. 1993;67:81-87.
20. 51Cr-labeled red cells. Transfusion. 1999;39:149-155.
21. 51Cr-labeled red cells. Transfusion. 1999;39:156-162.
22. De Jong K, Emerson RK, Butler J, Bastacky J, Mohandas N, Kuypers FA. Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia. Blood. 2001;98:1577-1584.
23. Cordle DG, Strauss RG, Lankford G, Mock DM. Antibodies provoked by the transfusion of biotin-labeled red cells. Transfusion. 1999;39:1065-1069.
24. King MJ, Hemming N. An assessment of the immunoprecipitation of blood-group antigens using biotinylated red cells. Transf Med. 1994;4: 195-204.
25. Cowley H, Wojda U, Cipolone KM, Procter JL, Stroncek DF, Miller JL. Biotinylation modifies red cell antigens. Transfusion. 1999;39:163-168.
26. Cavill I, Trevett D, Fisher J, Hoy T. The measurement of the total volume of red cells in man: a non-radioactive approach using biotin. Brit J Haematol. 1988;70:491-493.
27. Cohen RM, Franco RS, Khera PK, Smith EP, Lindsell CJ, Ciraolo PJ et al. Red cell lifespan heterogeneity in hematologically normal people is sufficient to alter HbA1c. Blood. 2008;112:4284-4291.
28. London JM, West R, Shemin D, Rittenberg D. On the origin of bile pigment in normal man. J Biol Chem. 1950;184:351-358.
29. Allison AC, Burn GP. Enzyme activity as a function of age in the human erythrocyte. Brit J Haematol. 1955;1:291-303.
30. Bernstein RE. Alterations in metabolic energetics and cation transport during aging of red cells. J Clin Invest. 1959;38:1572-1586.
31. Garby L, Hjelm M. Ultracentrifugal fractionation of human erythrocytes with respect to cell age. Blut. 1963;9:284-291.
32. Van Gastel C. De lipiden en enkele eigenschappen van de menselijke erythrocyt met betrekking tot zijn leeftijd. 1965; thesis, Rijksuniversiteit Utrecht.
33. Corash LM, Piomelli S, Chen HC, Seaman C, Gross E. Separation of erythrocytes according to age on a simplified density gradient. J Lab Clin Med. 1974;84:147-151.
34. Bosch FH, Werre JM, Roerdinkholder-Stoelwinder B, Huls TH, Willekens FL, Halie MR. Characteristics of red blood cell populations fractionated with a combination of counterflow centrifugation and Percoll separation. Blood. 1992;79:254-260.
35. Glader B. Destruction of erythrocytes. In: Greeg J, Foester J, Lukens J, Rodgers F, Paraskevas F, Glader B, editors. Wintrobe's Clinical Hematology. Philadelphia: Lippincott; 2004, pp. 249-265.
36. Lindbergh CA. A method for washing corpuscles in suspension. Science. 1932;75:415-416.
37. Lindahl PE. Principle of a counter-streaming centrifuge for the separation of particles of different sizes. Nature. 1948;161:648-649.
38. Sanderson RJ, Bird KE, Palmer NF, Brenman J. Design principles for a counterflow centrifugation cell separation chamber. Anal Biochem. 1976;71:615-622.
39. Sanderson RJ, Bird KE. Cell separations by counterflow centrifugation. Meth Cell Biol. 1977;15:1-14.
40. Mohandas N, Kim YR, Tycko DH, Orlik J, Wyatt J, Groner W. Accurate and independent measurement of volume and hemoglobin concentration of individual red cells by laser light scattering. Blood. 1986;68: 506-513.
41. Bunn HF, Haney DN, Kamin S, Gabbay KH, Gallop PM. The biosynthesis of human hemoglobin A1c. Slow glycosylation of hemoglobin in vivo. J Clin Invest. 1976;57:1652-1659.
42. Lasch J, Kullertz G, Opalka JR. Separation of erythrocytes into age-related fractions by density or size? Counterflow centrifugation. Clin Chem Lab Med. 2000;38:629-632.
43. Bosch FH, Werre JM, Schipper L, Roerdinkholder-Stoelwinder B, Huls TH, Willekens FLA et al. Characteristics of red blood cell populations fractionated with a combination of counterflow centrifugation and Percoll separation. Eur J Haematol. 1994;52:35-41.
44. Willekens FL, Bosch FH, Roerdinkholder-Stoelwinder B, Groenen-Dopp YA, Werre JM. Quantification of loss of haemoglobin components from the circulating red blood cell in vivo. Eur J Haematol. 1997;58:246-250.
45. Willekens FL, Roerdinkholder-Stoelwinder B, Groenen-Dopp YA, Bos HJ, Bosman GJ, van den Bos AG et al. Hemoglobin loss from erythrocytes in vivo results from spleen-facilitated vesiculation. Blood. 2003;101: 747-751.
46. Crosby WH. The pathogenesis of spherocytes and leptocytes (target-cells). Blood. 1952;7:261-274.
47. Crosby WH. Splenic remodeling of red cell surfaces. Blood. 1977;50: 643-645.
48. Clark MR, Shohet SB. Red cell senescence. Clin. Haematol. 1985;14: 223-257.
49. De Haan LD, Werre JM, Ruben AM, Huls AH, De Gier J, Staal GE. Reticulocyte crisis after splenectomy: evidence for delayed red cell maturation? Eur J Haematol. 1988;41:74-79.
50. De Haan LD, Werre JM, Ruben AM, Huls AH, De Gier J, Staal GE. Vacuoles in red cells from splenectomized subjects originate during cell life: association with glycosylated haemoglobin? Eur J Haematol. 1988;41:482-488.
51. De Haan LD, Werre JM, Ruben AM, Huls HA, De Gier J, Staal GE. Alterations in size, shape and osmotic behaviour of red cells after splenectomy: a study of their age dependence. Brit J Haematol. 1988;69:71-80.
52. Cooper RA, Jandl JH. The role of membrane lipids in the survival of red cells in hereditary spherocytosis. J Clin Invest. 1969;48:736-744.
53. Werre JM. Oorzaken van macroplanie van erythrocyten bij lever- en galwegenziekten. 1968; thesis, Rijksuniversiteit Utrecht.
54. Winterbourn CC, Batt RD. Lipid composition of human red cells of different ages. Biochimica et Biophysica Acta. 1970;202:1-8.
55. Shattil SJ, Cooper RA. Maturation of macroreticulocyte membranes in vivo. J Lab Clin Med. 1972;79:215-227.
56. Snyder LM, Fairbanks G, Trainor J, Fortier NL, Jacobs JB, Leb L. Properties and characterization of vesicles released by young and old human red cells. Brit J Haematol. 1985;59:513-522.
57. Houwen B. Reticulocyte maturation. Blood Cells. 1992;18:167-186.
58. Johnstone RM. Revisiting the road to the discovery of exosomes. Blood Cells Mol Dis. 2005;34:214-219.
59. Gevirtz NR, Nathan DG, Berlin NI. Erythrokinetic studies in primary hypersplenism with pancytopenia. Am J Med. 1962;32:148-152.
60. Koyama S, Kihira H, Aoki S, Ohnishi H. Postsplenectomy vacuole, a new erythrocytic inclusion body. Mie Medical Journal 1962;11:425-437.
61. Reinhart WH, Chien S. Red cell vacuoles: their size and distribution under normal conditions and after splenectomy. Am J Hematol. 1988;27: 265-271.
62. Holroyde CP, Oski FA, Gardner FH. The "pocked" erythrocyte. Red-cell surface alterations in reticuloendothelial immaturity of the neonate. New Engl J Med. 1969;281:516-520.
63. Holroyde CP, Gardner FH. Acquisition of autophagic vacuoles by human erythrocytes. Physiological role of the spleen. Blood. 1970;36:566-575.
64. Markus HS, Toghill PJ. Impaired splenic function in elderly people. Age Ageing. 1991;20:287-290.
65. Kent G, Minick OT, Volini FI, Orfei E. Autophagic vacuoles in human red cells. Am J Pathol. 1966;48:831-857.
66. Schnitzer B, Rucknagel DL, Spencer HH, Aikawa M. Erythrocytes: pits and vacuoles as seen with transmission and scanning electron microscopy. Science. 1971;173:251-252.
67. Crosby WH. Normal functions of the spleen relative to red blood cells: a review. Blood. 1959;14:399-408.
68. Lux SE, John KM. Isolation and partial characterization of a high molecular weight red cell membrane protein complex normally removed by the spleen. Blood. 1977;50:625-641.
69. Dumaswala UJ, Greenwalt TJ. Human erythrocytes shed exocytic vesicles in vivo. Transfusion. 1984;24:490-492.
70. Kay MMB. Mechanism of removal of senescent cells by human macrophages in situ. Proc Natl Acad Sci USA. 1975;72:3521-3525.
71. Kay MMB. Role of physiologic autoantibody in the removal of senescent human red cells. J Supramol Struct. 1978;9:555-567.
72. Kay MMB, Goodman SR, Sorensen K, Whitfield CF, Wong P, Zaki L et al. Senescent cell antigen is immunologically related to band 3. Proc Natl Acad Sci USA. 1983;80:1631-1635.
73. Kay MMB. Immunoregulation of cellular lifespan. Ann New York Acad Sci. 2005;1057:85-111.
74. Belo L, Rebelo I, Castro EM, Catarino C, Pereira-Leite L, Quintanilha A et al. Band 3 as a marker of erythrocyte changes in pregnancy. Eur J Haematol. 2002;69:145-151.
75. Ciccoli L, Rossi V, Leoncini S, Signorini C, Blanco-Garcia J, Aldinucci C et al. Iron release, superoxide production and binding of autologous IgG to band 3 dimers in newborn and adult erythrocytes exposed to hypoxia and hypoxia-reoxygenation. Biochimica et Biophysica Acta. 2004;1672:203-213.
76. Rossi V, Leoncini S, Signorini C, Buonocore G, Paffetti P, Tanganelli D et al. Oxidative stress and autologous immunoglobulin G binding to band 3 dimers in newborn erythrocytes. Free Rad Biol Med. 2006;40: 907-915.
77. Arese P, Turrini F, Schwarzer E. Band 3/complement-mediated recognition and removal of normally senescent and pathological human erythrocytes. Cell Physiol Biochem. 2005;16:133-146.
78. Low PS, Waugh SM, Zinke K, Drenckhahn D. The role of hemoglobin denaturation and band 3 clustering in red blood cell aging. Science. 1985;227:531-533.
79. Lelkes G, Fodor I, Lelkes G, Hollan SR, Verkleij AJ. The distribution and aggregatability of intramembrane particles in phenylhydrazine-treated human erythrocytes. Biochimica et Biophysica Acta. 1988;945:105-110.
80. Willekens FL, Werre JM, Groenen-Dopp YA, Roerdinkholder-Stoelwinder B, de Pauw B, Bosman GJ. Erythrocyte vesiculation: a self-protective mechanism? Brit J Haematol. 2008;141:549-556.
81. Lutz HU. Innate immune and non-immune mediators of erythrocyte clearance. Cell Mol Biol. 2004;50:107-116.
82. Willekens FL, Bos HJ, Roerdinkholder-Stoelwinder B, Groenen-Dopp YA, Van der Plas GC, Werre JM. Loss of anticomplement activity from circulating old red cells. Brit J Haematol. 1998;102:302.
83. Oldenborg PA, Zheleznyak A, Fang YF, Lagenaur CF, Gresham HD, Lindberg FP. Role of CD47 as a marker of self on red blood cells. Science. 2000;288:2051-2054.
84. McDonald JF, Zheleznyak A, Frazier WA. Cholesterol-independent interactions with CD47 enhance alphavbeta3 avidity. J Biol Chem. 2004;279: 17301-17311.
85. Arndt PA and Garratty G. Rh(null) red blood cells with reduced CD47 do not show increased interactions with peripheral blood monocytes. Brit J Haematol. 2004;125:412-414.
86. Kuypers FA, de Jong K. The role of phosphatidylserine in recognition and removal of erythrocytes. Cell Mol Biol. 2004;50:147-158.
87. Willekens FL, Bos HJ, Roerdinkholder-Stoelwinder B, Groenen-Dopp YA, Van der Plas GC, Werre JM. Conservation of lipid asymmetry in circulating old red cells. Brit J Haematol. 1998;102:302.
88. Hilarius PM, Ebbing IG, Dekkers DW, Lagerberg JW, de Korte D, Verhoeven AJ. Generation of singlet oxygen induces phospholipid scrambling in human erythrocytes. Biochemistry. 2004;43:4012-4019.
89. Krieser RJ, White K. Engulfment mechanism of apoptotic cells. Curr Opin Cell Biol. 2002;14:734-738.
90. Berckmans RJ, Nieuwland R, Boing AN, Romijn FP, Hack CE, Sturk A. Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb Haemost. 2001;85:639-646.
91. Shet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N et al. Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood. 2003;102:2678-2683.
92. Willekens FL, Werre JM, Kruijt JK, Roerdinkholder-Stoelwinder B, Groenen-Dopp YA, van den Bos AG et al. Liver Kupffer cells rapidly remove red blood cell-derived vesicles from the circulation by scavenger receptors. Blood. 2005;105:2141-2145.
93. Bosman GJ, Lasonder E, Groenen-Dopp YA, Willekens FL, Werre JM, Novotny VM. Comparative proteomics of erythrocyte aging in vivo and in vitro. J Prot. 2010;73:396-402.
94. Simak J, Gelderman MP. Cell membrane microparticles in blood and blood products: potentially pathogenic agents and diagnostic markers. Transf Med Rev. 2006;20:1-26.
95. Fourcade O, Simon MF, Viode C, Rugani N, Leballe F, Ragab Aet al. Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells. Cell. 1995;80:919-927.
96. Yang L, Andrews DA, Low PS. Lysophosphatidic acid opens a Ca(++) channel in human erythrocytes. Blood. 2000;95:2420-2425.
97. Chung SM, Bae ON, Lim KM, Noh JY, Lee MY, Jung YS et al. Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation in human erythrocytes. Arterioscl Thromb Vasc Biol. 2007;27:414-421.
98. Sims PJ, Wiedmer T. Repolarization of the membrane potential of blood platelets after complement damage: evidence for a Ca++-dependent exocytotic elimination of C5b-9 pores. Blood. 1986;68:556-561.
99. Iida K, Whitlow MB, Nussenzweig V. Membrane vesiculation protects erythrocytes from destruction by complement. J Immunol. 1991;147:2638-2642.
100. Reed CF. Phospholipid exchange between plasma and erythrocytes in man and the dog. J Clin Invest. 1968;47:749-760.
101. Van Deenen LL, De Gier J. Lipids of the red cell membrane. In: Surgenor DM, editor. The Red Blood Cell. New York: Academic Press; 1974, pp. 147-211.
102. Verkleij AJ, Nauta IL, Werre JM, Mandersloot JG, Reinders B, Ververgaert PH et al. The fusion of abnormal plasma lipoprotein (LP-X) and the erythrocyte membrane in patients with cholestasis studied by electronmicroscopy. Biochimica et Biophysica Acta. 1976;436:366-376.
103. Brossard N, Croset M, Normand S, Pousin J, Lecerf J, Laville M et al. Human plasma albumin transports [13C]docosahexaenoic acid in two lipid forms to blood cells. J Lipid Res. 1997;38:1571-1582.
104. Sens P, Gov N. Force balance and membrane shedding at the red-blood-cell surface. Phys Rev Lett. 2007;98:018102.