SAXS-LabDisk: A centrifugal microfluidic screening platform for protein structure analysis

Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Volumn , Issue , 2012, Pages 1450-1452

  Schwemmer, F ^a   Zehnle, S ^b   Paust, N ^b   Blanchet, C ^c   Rossle M ^c   Stetten, F V ^a,b   Zengerle, R ^a,b   Mark, D ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b HSG IMIT   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Aliquoting; Centrifugal microfluidics; Dilution; Mixing; SAXS

Indexed keywords

CENTRIFUGATION; DILUTION; MIXING; PROTEINS; SCREENING;

ALIQUOTING; CENTRIFUGAL MICROFLUIDICS; FULLY AUTOMATED; PROTEIN SAMPLES; PROTEIN STRUCTURE ANALYSIS; PROTEIN VOLUME; SAXS; SMALL ANGLE X-RAY SCATTERING;

MICROFLUIDICS;

EID: 84891676425     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (5)

1. Hura, G. L., Menon, A. L., Hammel, M., Rambo, R. P., Poole, F. L., Tsutakawa, S. E., Jenney, F. E., et al., Robust, highthroughput solution structural analyses by small angle X-ray scattering (SAXS), Nature methods, Nature Publishing Group, pp. 606-12 (2009).
2. Volkov, V., Svergun, D. I., Uniqueness of ab initio shape determination in small-angle scattering, Journal of Applied Crystallography, pp. 860-864., (2003).
3. Petoukhov, M. V., & Svergun, D. I.. Analysis of X-ray and neutron scattering from biomacromolecular solutions, Current opinion in structural biology, pp. 562-71 (2007).
4. David, G., & Pérez, J. Combined sampler robot and high-performance liquid chromatography: A fully automated system for biological small-angle X-ray scattering experiments at the Synchrotron SOLEIL SWING beamline. Journal of Applied Crystallography, International Union of Crystallography, pp. 892-900, (2009).
5. Noroozi, Z., Kido, H., Peytavi, R., Nakajima-Sasaki, R., Jasinskas, A., Micic, M., Felgner, P. L., et al., A multiplexed immunoassay system based upon reciprocating centrifugal microfluidics. The Review of scientific instruments, (2011).