Aloe vera/silk fibroin/hydroxyapatite incorporated electrospun nano?brous scaffold for enhanced osteogenesis

Journal of Biomaterials and Tissue Engineering

Volumn 4, Issue 1, 2014, Pages 9-19

  Suganya, S ^a   Venugopal, J ^b   Ramakrishna, S ^b   Lakshmi, B S ^a   Giri Dev, V R ^a  

^a ANNA UNIVERSITY   (India)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Aloe vera; Biomimetic; Bone tissue engineering; Electrospinning; Hydroxyapatite; Mineralization; Silk fibroin

Indexed keywords

EID: 84891643059     PISSN: 21579083     EISSN: 21579091     Source Type: Journal    
DOI: 10.1166/jbt.2014.1139     Document Type: Article

References (23)

1. R. Langer and J. P. Vacanti, Tissue engineering. Science 260, 920 (1993).
2. B. Li and R. M. Aspden, Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis or osteoarthritis. J. Bone Min. Res. 12, 641 (1997).
3. J. R. Porter, T. T. Ruckh, and K. C. Popat, Bone tissue engineering: A review in bone biomimetics and drug delivery strategies. Biotechnol. Progr. 25, 1539 (2009).
4. A. Seidi and M. Ramalingam, Engineering of gradient biomaterials as biomimetic systems for tissue engineering. J. Biomater. Tissue Eng. 1, 139 (2011).
5. S. Suganya, T. Senthil Ram, B. S. Lakshmi, and V. R. Giridev, Herbal drug incorporated antibacterial nanofibrous mat fabricated by electrospinning: An excellent matrix for wound dressings. J. Appl. Polym. Sci. 121, 2893 (2011).
6. B. Dhandayuthapani, Y. Yoshida, T. Maekawa, and D. Sakthi Kumar, Polymeric scaffolds in tissue engineering application: A review. Int. J. Polym. Sci. 201, 11 (2011).
7. C. P. Dhanalakshmi, L. Vijayalakshmi, and V. Narayanan, In situ preparation and characterization of nano carbonated hydroxyapatite/poly(4-vinyl pyridine-co-styrene) composite and it's biomedical application. J. Biomater. Tissue Eng. 2, 314 (2012).
8. V. Guarino, F. Causa, and L. Ambrosio, Bioactive scaffolds for bone and ligament tissue. Expert Rev. Med. Devices 4, 405 (2007).
9. I. Yuvarani, S. Senthil Kumar, J. Venkatesan, S. K. Kim, and P. N. Sudha, Preparation and characterization of curcumin coated chitosan-alginate blend for wound dressing application. J. Biomater. Tissue Eng. 2, 53 (2012).
10. L. Susan, R. Seeram, and R. Murugan, Development of nanofiber biomaterials and stem cells in tissue engineering. J. Biomater. Tissue Eng. 1, 111 (2011).
11. P. Chantarawaratit, P. Sangvanich, W. Banlunara, K. Soontornvipart, and P. Thunyakitpisal, Acemannan sponges stimulate alveolar bone cementum and periodontal ligament regeneration in a canine Class II furcation defect model. J. Periodontal Res. DOI:10.1111/jre.12090 (2013).
12. Q. Lu, S. Zhang, K. Hu, Q. Feng, C. Cao, and F. Cui, Cytocompatibility and blood compatibility of multifunctional fibroin/collagen/ heparin scaffolds. Biomaterials 28, 2306 (2007).
13. Y. Wang, H. J. Kim, N. G. Vunjak, and D. L. Kaplan, Stem cell-based tissue engineering with silk biomaterials. Biomaterials 27, 6064 (2006).
14. G. H. Altman, F. Diaz, C. Jakuba, T. Calabro, R. L. Horan, J. Chen, H. Lu, J. Richmond, and D. L. Kaplan, Silk-based biomaterials. Biomaterials 24, 401 (2003).
15. Y. Yang, X. Chen, F. Ding, P. Zhang, J. Liu, and X. Gu, Biocompatibility evaluation of silk fibroin with peripheral nerve tissues and cells in vitro. Biomaterials 28, 1643 (2007).
16. Y. Liu, G. Wang, Y. Cai, H. Ji, and X. Zhao, In vitro effects of nanophase hydroxyapatite particles on proliferation and ostegenic differentiation of bone marrow-derived mesenchymal stem cells. J. Biomed. Mater. Res. Part A 90A, 1083 (2009).
17. D. D. Deligianni, N. D. Katsala, P. G. Koutsoukos, and Y. F. Missirlis, Effect of surface roughness of hydroxyapatite on human bone marrow cell adhesion, proliferation, differentiation and detachment strength. Biomaterials 22, 87 (2001).
18. G. Chen, T. Ushida, and T. Tateishi, Scaffold design for tissue engineering. Engineering Macromol. Biosci. 2, 67 (2002).
19. J. R. Venugopal, S. Low, A. T. Choon, A. B. Kumar, and S. Ramakrishna, Nanobioengineered electrospun composite nanofibres and osteoblasts for bone regeneration. Artif. Organs. 32, 388 (2008).
20. H. C. Anderson, J. B. Sipe, L. Hessle, R. Dhanyamraju, E. Atti, N. P. Camacho, and J. L. Millan, Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice. Am. J. Pathol. 164, 841 (2004).
21. F. Liu, L. Malaval, and J. E. Aubin, Global amplification polymerase chain reaction reveals novel transitional stages during osteoprogenitor differentiation. J. Cell. Sci. 116, 1787 (2003).
22. M. F. Young, J. M. Kerr, K. Ibaraki, A. M. Heegaard, and P. G. Robey, Structure, expression, and regulation of the major noncollagenous matrix proteins of bone. Clin. Orthop. Relat. Res. 281, 275 (1992).
23. K. Kim, D. Dean, A. Lu, and A. G. Mikos, Early osteogenic signal expression of rat bone marrow stromal cells is influenced by both hydroxyapatite nanoparticle content and initial cell seeding density in biodegradable nanocomposite scaffolds. Acta Biomater. 7, 1249 (2011).