Predictors of mortality after emergency colectomy for Clostridium difficile colitis: An analysis of ACS-NSQIP

Annals of Surgery

Volumn 259, Issue 1, 2014, Pages 148-156

  Lee, David Y ^a   Chung, Eunice L ^a   Guend, Hamza ^a   Whelan, Richard L ^a   Wedderburn, Raymond V ^a   Rose, Keith M ^a  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

Author keywords

ACS NSQIP colectomy; Clostridium difficile colitis; Colectomy for Clostridium difficile colitis; Fulminant Clostridium difficile colitis

Indexed keywords

STEROID;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; BLOOD CLOTTING DISORDER; CAUSE OF DEATH; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLOSTRIDIUM DIFFICILE INFECTION; COLON RESECTION; COMORBIDITY; COMPARATIVE STUDY; CONGESTIVE HEART FAILURE; CONTAMINATION; DIALYSIS; EMERGENCY SURGERY; FEMALE; FUNCTIONAL STATUS; HEART ARREST; HUMAN; INTERNATIONAL NORMALIZED RATIO; KIDNEY FAILURE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RESPIRATORY FAILURE; SHOCK; STEROID THERAPY; SURGICAL MORTALITY; SURVIVOR; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TOTAL COLON RESECTION; TRANSFUSION; UREA NITROGEN BLOOD LEVEL; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; COLECTOMY; DATABASES, FACTUAL; EMERGENCIES; ENTEROCOLITIS, PSEUDOMEMBRANOUS; HUMANS; MIDDLE AGED; RISK FACTORS;

EID: 84891635552     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e31828a8eba     Document Type: Article

References (30)

1. McFarland LV. Epidemiology, risk factors and treatments for antibioticassociated diarrhea. Dig Dis. 1998;16:292-307.
2. Bartlett JG, Chang TW, Onderdonk AB. Comparison of five regimens for treatment of experimental clindamycin-Associated colitis. J Infect Dis. 1978;138:81-86.
3. Cohen SH, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol. 2010;31:431-455.
4. Fawley WN, Wilcox MH. Molecular epidemiology of endemic Clostridium difficile infection. Epidemiol Infect. 2001;126:343-350.
5. Redelings MD, Sorvillo F, Mascola L. Increase in Clostridium difficile-related mortality rates, United States, 1999-2004. Emerg Infect Dis. 2007;13:1417-1419.
6. McDonald LC, Owings M, Jernigan DB. Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003. Emerg Infect Dis. 2006;12:409-415.
7. Association for Professionals in Infection Control and Epidemiology (APIC). National Prevalence Study of Clostridium difficile inU.S. Healthcare Facilities. Washington, DC: APIC; 2008.
8. Osman KA, Ahmed MH, Hamad MA, et al. Emergency colectomy for fulminant Clostridium difficile colitis: Striking the right balance. Scand J Gastroenterol. 2011;46:1222-1227.
9. Pepin J,Vo TT, BoutrosM, et al. Risk factors for mortality following emergency colectomy for fulminant Clostridium difficile infection. Dis Colon Rectum. 2009;52:400-405.
10. Hall JF, Berger D. Outcome of colectomy for Clostridium difficile colitis: A plea for early surgical management. Am J Surg. 2008;196:384-388.
11. Sailhamer EA, Carson K, Chang Y, et al. Fulminant Clostridium difficile colitis: Patterns of care and predictors of mortality. Arch Surg. 2009;144:433-439; discussion 439-40.
12. Dudukgian H, Sie E, Gonzalez-Ruiz C, et al. C. difficile colitis-predictors of fatal outcome. J Gastrointest Surg. 2010;14:315-322.
13. Gash K, Brown E, Pullyblank A. Emergency subtotal colectomy for fulminant Clostridium difficile colitis-is a surgical solution considered for all patients? Ann R Coll Surg Engl. 2010;92:56-60.
14. Greenstein AJ, Byrn JC, Zhang LP, et al. Risk factors for the development of fulminant Clostridium difficile colitis. Surgery. 2008;143:623-629.
15. Lamontagne F, Labbe AC, Haeck O, et al. Impact of emergency colectomy on survival of patients with fulminant Clostridium difficile colitis during an epidemic caused by a hypervirulent strain. Ann Surg. 2007;245: 267-272.
16. Longo WE,Mazuski JE,VirgoKS, et al.Outcome after colectomy for Clostridium difficile colitis. Dis Colon Rectum. 2004;47:1620-1626.
17. Byrn JC, Maun DC, Gingold DS, et al. Predictors of mortality after colectomy for fulminant Clostridium difficile colitis. Arch Surg. 2008;143:150-154; discussion 155.
18. Klipfel AA, Schein M, Fahoum B, et al. Acute abdomen and Clostridium difficile colitis: Still a lethal combination. Dig Surg. 2000;17:160-163.
19. Bradbury AW, Barrett S. Surgical aspects of Clostridium difficile colitis. Br J Surg. 1997;84:150-159.
20. Pepin J, Valiquette L, AlaryME, et al. Clostridium difficile-Associated diarrhea in a region ofQuebec from 1991 to 2003: A changing pattern of disease severity. CMAJ. 2004;171:466-472.
21. American College of Surgeons National Surgical Quality Improvement Program. 2012. http://site.acsnsqip.org/program-specifics/ data-collection- Analysis-And-reporting./ Accessed 31 May, 2012.
22. ACS NSQIP User Guide for the 2010 Participant Use Data File 2012. http:// site.acsnsqip.org/wp-content/uploads/2012/03/2010-User-Guide FINAL.pdf. Accessed 31 May, 2012.
23. Berard F, Gandon J. Postoperative wound infections: The influence of ultraviolet irradiation of the operating room and of various other factors. Ann Surg. 1964;160(suppl 2):1-192.
24. Issa M, Vijayapal A, Graham MB, et al. Impact of Clostridium difficile on inflammatory bowel disease. Clin Gastroenterol Hepatol. 2007;5:345-351.
25. Monaghan T, Boswell T, Mahida YR. Recent advances in Clostridium difficileassociated disease. Gut. 2008;57:850-860.
26. McDonald LC, Killgore GE, Thompson A, et al. An epidemic, toxin genevariant strain of Clostridium difficile. N Engl J Med. 2005;353:2433-2441.
27. Loo VG, Poirier L,MillerMA, et al. A predominantly clonalmulti- institutional outbreak of Clostridium difficile-Associated diarrhea with high morbidity and mortality. N Engl J Med. 2005;353:2442-2449.
28. DallalRM, HarbrechtBG, BoujoukasAJ, et al. Fulminant Clostridium difficile: An underappreciated and increasing cause of death and complications. Ann Surg. 2002;235:363-372.
29. Seder CW,VillalbaMR, Jr, Robbins J, et al. Early colectomymay be associated with improved survival in fulminant Clostridium difficile colitis: An 8-year experience. Am J Surg. 2009;197:302-307.
30. Ali SO, Welch JP, Dring RJ. Early surgical intervention for fulminant pseudomembranous colitis. Am Surg. 2008;74:20-26.