Synthesis and biological activity of 5-aryl-4-acyl-3-hydroxy-1-(2- piperazin-1-ylethyl)-2,5-dihydropyrrol-2-ones and their derivatives

Pharmaceutical Chemistry Journal

Volumn 47, Issue 9, 2013, Pages 485-489

  Gein, V L ^a   Syropyatov, B Ya ^a   Kasimova, N N ^a   Dozmorova, N V ^a   Voronina, E V ^a   Vakhrin, M I ^a  

^a PERM STATE PHARMACEUTICAL ACADEMY   (Russian Federation)

Author keywords

3,4 diaryl 4,6 dihydro 5 (2 piperazin 1 ylethyl)pyrrolo 3,4 c pyrazol 6 ones; 5 aryl 4 acyl 3 hydroxy 1 (2 piperazin 1 ylethyl) 2,5 dihydropyrrol 2 ones; acute toxicity; antimicrobial activity; influence on blood coagulation; synthesis

Indexed keywords

4,6 DIHYDRO 4 (4 METHOXYPHENYL) 5 (2 PIPERAZIN 1 YL ETHYL) 3 PHENYLPYRROLO[3,4 C]PYRAZOL 6 ONE; 5 ARYL 4 ACYL 3 HYDROXY 1 (2 PIPERAZIN 1 YLETHYL) 2,5 DIHYDROPYRROL 2 ONE DERIVATIVE; ANTIINFECTIVE AGENT; ETAMSYLATE; ETHACRIDINE LACTATE; HEMOSTATIC AGENT; MERCURIC CHLORIDE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; BLOOD CLOTTING; CHEMICAL REACTION; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FEMALE; HEMOSTASIS; MALE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; NUCLEOPHILICITY; PHYSICAL CHEMISTRY; STAPHYLOCOCCUS AUREUS;

EID: 84891627934     PISSN: 0091150X     EISSN: 15739031     Source Type: Journal    
DOI: 10.1007/s11094-013-0986-2     Document Type: Article

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