LC-MALDI MS for Polymer Characterization

MALDI Mass Spectrometry for Synthetic Polymer Analysis

Volumn 175, Issue , 2009, Pages 247-265

  Weidner, Steffen M ^a   Falkenhagen, Jana ^a  

^a BAM FEDERAL INSTITUTE FOR MATERIALS RESEARCH AND TESTING   (Germany)

Author keywords

LC MALDI MS for polymer characterization; Mixtures of polymers with different end groups (Functionality Type Distribution FTD ); Online coupling methods

Indexed keywords

CHEMISTRY;

END GROUPS; LC-MALDI; ON-LINE COUPLING; POLYMER CHARACTERIZATION;

POLYMERS;

EID: 84891626586     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470567234.ch11     Document Type: Chapter

References (64)

1. Gorshkov, A.V.; Much, H.; Becker, H. et al., Chromatographic investigations of macromolecules in the critical range of liquid-chromatography: 1. functionality type and composition distribution in polyethylene oxide and polypropylene oxide copolymers, Journal of Chromatography, 1990, 523, 91-102.
2. Schulz, G.; Much, H.; Krueger, H. et al., Determination of functionality and molecular-weight distribution by orthogonal chromatography, Journal of Liquid Chromatography, 1990, 13 (9), 1745-1763.
3. Pasch, H.; Much, H.; Schulz, G., Determination of polymer heterogeneity by two-dimensional orthogonal liquid chromatography, Trends in Polymer Science, 1993, 3, 643.
4. Krüger, R.P.; Much, H.; Schulz, G., International Journal of Polymer Analysis and Characterization, 1996, 2, 221.
5. Chang, T.Y.; Lee, H.; Lee, W. et al., Polymer characterization by temperature gradient interaction chromatography, Macromolecular Chemistry and Physics, 1999, 200 (10), 2188-2204.
6. Belenki, B.G.; Gankina, E.; Tennikov, N., et al. The chromatographic study of the basic regularities of macromolecules adsorption on the porous sorbents, Doklady Akademii Nauk SSSR, 1976, 231, 1147.
7. Belenki, B.G.; Gankina, E.; Tennikov, N. et al., Fundamental aspects of adsorption chromatography of polymers and their experimental verification by thin layer chromatography, Journal of Chromatography, 1978, 147, 99.
8. Falkenhagen, J., Kopplung von chromatographischen und spektroskopischen Methoden zur Bestimmung der Heterogenitäten von Polymeren. PhD Thesis, Berlin: Mensch & Buch Verlag, 1998.
9. Pasch, H.; Trathnigg, B., HPLC of Polymers. Berlin: Springer, 1997.
10. Ling, H.; Liang, L.H.; Lubman, D.M., Continuous-flow MALDI mass spectrometry using an ion trap/reflectron time-of-flight detector, Analytical Chemistry, 1995, 67, 4127.
11. MacFadden, W.H.; Schwarz, H.L.; Evans, S.J., Direct analysis of liquid chromatographic effluents, Journal of Chromatography, 1976 (122), 389.
12. Murray, K.K.; He, L., 337 nm matrix-assisted laser desorption/ionization of single aerosol particles, Analytical Chemistry News & Features, 1999, 518.
13. Murray, K.K.; Russell, D.H., Liquid sample introduction for matrix-assisted laser-desorption ionization, Analytical Chemistry, 1993, 65 (18), 2534-2537.
14. Beeson, M.D.; Murray, K.K.; Russell, D.H., Aerosol matrix-assisted laser-desorption ionization-effects of analyte concentration and matrix-to-analyte ratio, Analytical Chemistry, 1995, 67 (13), 1981-1986.
15. Murray, K.K.; Lewis, T.M.; Beeson, M.D. et al., Aerosol matrix-assisted laser-desorption ionization for liquid-chromatography time-of-flight mass-spectrometry, Analytical Chemistry, 1994, 66 (10), 1601-1609.
16. Fei, X.; Murray, K.K., On-line coupling of gel permeation chromatography with MALDI mass spectrometry, Analytical Chemistry, 1996, 68 (20), 3555-3560.
17. Fei, X.; Wei, G.; Murray, K.K., Aerosol MALDI with a reflectron time-of-flight mass spectrometer, Analytical Chemistry, 1996, 68 (7), 1143-1147.
18. Tsuda, T.; Yamamoto, K., Device to transform the liquid-chromatographic effluent to a continuous solid plug-a new approach to direct liquid introduction for liquid-chromatography mass-spectrometry, Journal of Chromatography, 1988, 456 (2), 363-369.
19. Williams, E.R.; Jones, G.C.; Fang, L.; Zare, R.N., Using tandem time-of-flight mass spectrometry, Proceedings of the ASMS Conference on Mass Spectrometry, 1991, 39, 1273.
20. Li, L.; Wang, A.P.L.; Coulson, L.D., Continuous-flow matrix-assisted laser desorption ionization mass-spectrometry, Analytical Chemistry, 1993, 65 (4), 493-495.
21. Nagra, D.S.; Li, L., Liquid chromatography-time-of-flight mass-spectrometry with continuous-flow matrix-assisted laser-desorption ionization, Journal of Chromatography A, 1995, 711 (2), 235-245.
22. Laiko, V.V.; Baldwin, M.A.; Burlingame, A.L., Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry, Analytical Chemistry, 2000, 72 (4): 652-657.
23. Daniel, J.M.; Ehala, S.; Fries, S.D. et al., On-line atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry, Analyst, 2004, 129 (7), 574-578.
24. Available at http://www.apmaldi.com/.
25. Available at http://www.kranalytical.co.uk/mass-spec.html.
26. Montaudo, G.; Montaudo, M.; Puglisi, C. et al., Molecular-weight distribution of poly(dimethylsiloxane) by combining matrix-assisted laser-desorption ionization time-of-flight mass-spectrometry with gel-permeation chromatography fractionation, Rapid Communications in Mass Spectrometry, 1995, 9 (12), 1158-1163.
27. Pasch, H.; Rode, K., Use of matrix-assisted laser-desorption/ionization mass-spectrometry for molar mass-sensitive detection in liquid-chromatography of polymers, Journal of Chromatography A, 1995, 699 (1-2), 21-29.
28. Danis, P.O.; Saucy, A.; Huby, F.J., Applications of MALDI/TOF mass spectrometry coupled to gel permeation chromatography, Abstracts of Papers of the American Chemical Society, 1996, 211, 368-POLY.
29. Nielen, M.W.F.; Malucha, S., Characterization of polydisperse synthetic polymers by size-exclusion chromatography matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Rapid Communications in Mass Spectrometry, 1997, 11 (11), 1194-1204.
30. Wachsen, O.; Reichert, K.H.; Krueger, R.P. et al., Thermal decomposition of biodegradable polyesters: 3. studies on the mechanisms of thermal degradation of oligo-L-lactide using SEC, LACCC and MALDI-TOF-MS, Polymer Degradation and Stability, 1997, 55 (2), 225-231.
31. Kruger, R.P.; Much, H.; Schulz, G. et al., New aspects of determination of polymer heterogeneity by 2-dimensional orthogonal liquid chromatography and MALDI-TOF-MS, Macromolecular Symposia, 1996, 110, 155-176.
32. Available at http://www.lcpackings.com/products/Instruments/Probot01.html.
33. Available at http://www.kromatek.co.uk/MALDI_Fraction_Collector_40.asp.
34. Available at http://www.gilson.com/Products/product.asp?pID=116.
35. Available at http://www.sunchrom.de/pdf/SunChrom%20SunCollect.pdf.
36. Keil, O.; LaRiche, T.; Deppe, H. et al., Hyphenation of capillary high-performance liquid chromatography with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for nano-scale screening of single-bead combinatorial libraries, Rapid Communications in Mass Spectrometry, 2002, 16 (8), 814-820.
37. Nielen, M.W.F., Polymer analysis by micro-scale size exclusion chromatography MALDI time-of-flight mass spectrometry with a robotic interface, Analytical Chemistry, 1998, 70 (8), 1563-1568.
38. Grimm, R., Capillary LC with automated on-line microfraction collection onto MALDI/TOF MS targets, International Biotechnology Laboratory, 1997, 58, 17-21.
39. Available from: http://www.labconnections.com/products.htm.
40. Krüger, R.-P.; Falkenhagen, J.; Schulz, G.; Gloede, J., Charakterisierung von Calixarenen durch Kopplung von Flüssigkeitschromatographie und Maldi-TOF-MS, GIT Fachzeitschrift fuer Labor, 2001, 45, 380.
41. Montag, P.; Falkenhagen, J.; Krueger, R.P., Strukturanalyse in komplexen Polymersystemen, CLB Chemie in Labor und Biotechnik, 1999, 50, 253-257.
42. Falkenhagen, J.; Schulz, G.; Weidner, S. et al., Liquid adsorption chromatography near critical conditions of adsorption coupled with matrix-assisted laser desorption/ionization mass spectrometry, International Journal of Polymer Analysis and Characterization, 2000, 5 (4-6), 549-562.
43. Falkenhagen, J.; Weidner, S., Detection limits of matrix-assisted laser desorption/ionisation mass spectrometry coupled to chromatography-a new application of solvent-free sample preparation, Rapid Communication in Mass Spectrometry, 2005, 19, 3724-3730.
44. Maziarz, E.P.; Liu, M., A modified thermal deposition unit for gel-permeation chromatography with matrix-assisted laser desorption/ionization and electrospray ionization time-of-flight analysis, European Journal of Mass Spectrometry, 2002, 8 (5), 397-401.
45. Kona, B.; Weidner, S.; and J.F. Friedrich, Epoxidation of polydienes investigated by MALDI-TOF mass spectrometry and GPC-MALDI coupling, International Journal of Polymer Analysis and Characterization, 2005, 10 (1-2), 85-108.
46. Zhang, B.Y.; McDonald, C.; Li, L., Combining liquid chromatography with MALDI mass spectrometry using a heated droplet interface, Analytical Chemistry, 2004, 76 (4), 992-1001.
47. Young, J.B.; Li, L., Impulse-driven heated-droplet deposition interface for capillary and microbore LC-MALDI MS and MS/MS. Analytical Chemistry, 2007, 79 (15), 5927-5934.
48. Pasch, H.; Schrepp, W., MALDI-TOF Mass Spectrometry of Polymers. Berlin, Heidelberg and New York: Springer, 2003.
49. Montaudo, G.; Lattimer, R.P., Mass Spectrometry of Polymers. Boca Raton, FL, London, New York, and Washington, D.C.: CRC Press, 2002.
50. Rader, H.J.; Spikermann, J.; Kreyenschmidt, M. et al., MALDI-TOF mass spectrometry in polymer analytics: 2. molecular weight analysis of rigid-rod polymers, Macromolecular Chemistry and Physics, 1996, 197 (10), 3285-3296.
51. Belu, A.M.; DeSimone, J.M.; Linton, R.W. et al., Evaluation of matrix-assisted laser desorption ionization mass spectrometry for polymer characterization, Journal of the American Society for Mass Spectrometry, 1996, 7 (1), 11-24.
52. Tatro, S.R.; Baker, G.R.; Fleming, R. et al., Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry: determining Mark-Houwink-Sakurada parameters and analyzing the breadth of polymer molecular weight distributions, Polymer, 2002, 43 (8), 2329-2335.
53. Montaudo, M.S., Full copolymer characterization by SEC-NMR combined with SEC-MALDI, Polymer, 2002, 43 (5), 1587-1597.
54. Maziarz, E.P.; Liu, X.M.; Quinn E.T. et al., Detailed analysis of alpha,omega-bis(4-hydroxybutyl) poly(dimethylsiloxane) using GPC-MALDI TOF mass spectrometry, Journal of the American Society for Mass Spectrometry, 2002, 13 (2), 170-176.
55. Esser, E.; Keil, C.; Braun, D. et al., Matrix-assisted laser desorption/ionization mass spectrometry of synthetic polymers: 4. coupling of size exclusion chromatography and MALDI-TOF using a spray-deposition interface, Polymer, 2000, 41 (11), 4039-4046.
56. Montaudo, M.S., Puglisi, C.; Samperi, F. et al., Application of size exclusion chromatography matrix-assisted laser desorption/ionization time-of-flight to the determination of molecular masses in polydisperse polymers, Rapid Communications in Mass Spectrometry, 1998, 12 (9), 519-528.
57. Kruger, R.P.; Much, H.; Schulz, G., Determination of functionality and molar-mass distribution of aliphatic polyesters by orthogonal liquid-chromatography: 1. off-line investigation of poly(1,6-hexanediol adipates), Journal of Liquid Chromatography, 1994, 17 (14-15), 3069-3090.
58. Keil, C.; Esser, E.; Pasch, H., Matrix-assisted laser desorption/ionization mass spectrometry of synthetic polymers: 5. analysis of poly(propylene oxide)s by coupled liquid chromatography at the critical point of adsorption and MALDI-TOF mass spectrometry, Macromolecular Materials and Engineering, 2001, 286 (3), 161-167.
59. Trathnigg, B., Maier, B.; Schulz, G. et al., Characterization of polyethers using different methods: SFC, LAC and SEC with different detectors, and MALDI-TOF-MS, Macromolecular Symposia, 1996, 110, 231-240.
60. Mengerink, Y.; Peters, R.; deKoster, C.G. et al., Separation and quantification of the linear and cyclic structures of polyamide-6 at the critical point of adsorption, Journal of Chromatography A, 2001, 914 (1-2), 131-145.
61. Pasch, H.; Deffieux, A.; Ghahary, R. et al., Analysis of macrocyclic polystyrenes: 2. mass spectrometric investigations, M acromolecules, 1997, 30 (1), 98-104.
62. Weidner, S.; Kuhn, G.; Just, U., Characterization of oligomers in poly(ethylene-terephthalate) by matrix-assisted laser-desorption ionization mass-spectrometry, Rapid Communications in Mass Spectrometry, 1995, 9 (8), 697-702.
63. Weidner, S.M.; Just, U.; Wittke, W. et al., Analysis of modified polyamide 6.6 using coupled liquid chromatography and MALDI-TOF-mass spectrometry, International Journal of Mass Spectrometry, 2004, 238 (3), 235-244.
64. Falkenhagen, J.; Kruger, R.-P.; Schulz, G., Characterization of silicon-containing polymers by coupling of HPLC-separation methods with MALDI-TOF mass spectrometry. In Silicon Chemistry-From Small Molecules to Extended Systems (Jutzi, P.; Schubert, U., editors). Wiley-VCH: Weinheim, 2003, pp. 406-418.