A fully integrated 8-channel closed-loop neural-prosthetic cmos soc for real-time epileptic seizure control

IEEE Journal of Solid-State Circuits

Volumn 49, Issue 1, 2014, Pages 232-247

  Chen, Wei Ming ^a   Chiueh, Herming ^b   Chen, Tsan Jieh ^b   Ho, Chia Lun ^a   Jeng, Chi ^a   Ker, Ming Dou ^a   Lin, Chun Yu ^c   Huang, Ya Chun ^d   Chou, Chia Wei ^d   Fan, Tsun Yuan ^d   Cheng, Ming Seng ^d   Hsin, Yue Loong ^a   Liang, Sheng Fu ^d   Wang, Yu Lin ^d   Shaw, Fu Zen ^d   Huang, Yu Hsing ^d   Yang, Chia Hsiang ^a   Wu, Chung Yu ^a  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Closed loop control; Epilepsy; Neural prosthesis; Neuron modulation; System on Chip (SoC); Wireless power transmission

Indexed keywords

CLOSED-LOOP CONTROL; DETECTION ACCURACY; ELECTRICAL STIMULATIONS; EPILEPSY; ON-OFF KEYING MODULATIONS; SYSTEM-ON-CHIP; TRANSMISSION SYSTEMS; WIRELESS POWER TRANSMISSION;

APPLICATION SPECIFIC INTEGRATED CIRCUITS; COMPUTATION THEORY; CUTOFF FREQUENCY; MODULATION; NEURAL PROSTHESES; NEUROPHYSIOLOGY; PROSTHETICS;

ANALOG TO DIGITAL CONVERSION;

EID: 84891626009     PISSN: 00189200     EISSN: None     Source Type: Journal    
DOI: 10.1109/JSSC.2013.2284346     Document Type: Article

References (42)

1. P. Kwan, S. C. Schachter, and M. J. Brodie, "Current concepts: Drugresistant epilepsy," N. Engl. J. Med., vol. 365, no. 10, pp. 919-926, Sep. 2011.
2. E. F. Chang and N. M. Barbaro, "Epilepsy surgery: The emerging field of neuromodulation," Neurosurg Clin N. Amer., vol. 22, no. 4, pp. ix-x, Oct. 2011.
3. F. A. Al-Otaibi, C. Hamani, and A. M. Lozano, "Neuromodulation in epilepsy," Neurosurgery, vol. 69, no. 4, pp. 957-979, Oct. 2011.
4. P. R. Gigante and R. R. Goodman, "Responsive neuromodulation for the treatment of epilepsy," Neurosurg Clin N. Amer., vol. 22, no. 4, pp. 477-480, Oct. 2011.
5. J. C. LaManna, K. A. McCracken,M. Patil, and O. J. Prohaska, "Stimulus- activated changes in brain tissue temperature in the anesthetized rat," Metabolic Brain Disease, vol. 4, pp. 225-237, 1989. (Pubitemid 20091504)
6. S. Kim, P. Tathireddy, R. A. Normann, and F. Solzbacher, "Thermal impact of an active 3-D microelectrode array implanted in the brain," IEEE Trans. Neural Syst. Rehabil. Eng., vol. 15, no. 4, pp. 493-501, Dec. 2007. (Pubitemid 350274176)
7. J. Yoo, L. Yan, D. E. Damak, M. A. B. Altaf, A. H. Shoeb, and A. P. Chandrakasan, "An 8-channel scalable EEG acquisition SoC with patient-specific seizure classification and recording processor," IEEE J. Solid-State Circuits, vol. 48, no. 1, pp. 214-228, Jan. 2013.
8. M. Salam, M. Sawan, and D. Nguyen, "A novel low-power-implantable epileptic seizure-onset detector," IEEE Trans. Biomed. Circuits Syst., vol. 5, no. 6, pp. 568-578, Dec. 2011.
9. M. Azin, D. Guggenmos, S. Barbay, R. Nudo, and P. Mohseni, "A battery- powered activity-dependent intracortical microstimulation ic for brain-machine-brain interface," IEEE J. Solid-State Circuits, vol. 46, no. 4, pp. 731-745, Apr. 2011.
10. W.-M. Chen, H. Chiueh, T.-J. Chen, C.-L. Ho, C. Jeng, S.-T. Chang, M.-D. Ker, C.-Y. Lin, Y.-C. Huang, T.-Y. Fan, M.-S. Cheng, C.-W. Chou, S.-F. Liang, T.-C. Chien, S.-Y. Wu, Y.-L. Wang, F.-Z. Shaw, Y.-H. Huang, C.-H. Yang, J.-C. Chiou, C.-W. Chang, L.-C. Chou, and C.-Y. Wu, "A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control," in IEEE Int. Solid-State Circuits Conf. Dig. Tech. Papers, Feb. 2013, pp. 286-287.
11. A. A. Boulton, G. B. Baker, and C. H. Vanderwolf, Neurophysiological Techniques: II. Applications to Neural Systems. Berlin, Germany: Springer, 1990.
12. E. Leuthardt, G. Schalk, J. Wolpaw, J. Ojemann, and D. Moran, "A brain-computer interface using electrocorticographic signals in human," J. Nerual Eng., vol. 1, no. 2, pp. 63-71, 2004. (Pubitemid 41079659)
13. R. R. Harrison and C. Charles, "A low-power low-noise CMOS amplifier for neural recording applications," IEEE J. Solid-State Circuits, vol. 38, no. 6, pp. 958-965, Jun. 2003.
14. X. Zou, W. S. Liew, L. Yao, and Y. Libin, "A 1 V 22 uW 32-channel implantable EEG recording IC," in IEEE Int. Solid-State Circuits Conf. Dig. Tech. Papers, Feb. 2010, pp. 126-127.
15. F. Heer, S. Hafizovic, W. Franks, A. Blau, C. Ziegler, and A. Hierlemann, "CMOS microelectrode array for bidirectional interaction with neuronal networks," IEEE J. Solid-State Circuit, vol. 41, no. 7, pp. 1620-1629, Jul. 2006. (Pubitemid 44109297)
16. Y.-F. Lyu, C.-Y.Wu, L.-C. Liu, and W.-M. Chen, "A low power 10 Bit 500 kS/s delta-modulated SAR ADC (DMSAR ADC) for implantable medical devices," in Proc. IEEE Int. Symp. Circuits Syst., May 2013, pp. 2046-2049.
17. T.-J. Chen, H. Chiueh, S.-F. Liang, S.-T. Chang, C. Jeng, Y.-C. Hsu, and T.-C. Chien, "The implementation of a low-power biomedical signal processor for real-time epileptic seizure detection on absence animal models," IEEE J. Emerg. Sel. Topic Circuits Syst., vol. 1, no. 4, pp. 613-621, Dec. 2011.
18. S. Liang, H. Wang, and W. Chang, "Combination of EEG complexity and spectral analysis for epilepsy diagnosis and seizure detection," EURASIP J. Adv. Signal Process., vol. 2010, pp. 1-15, 2010.
19. S.-F. Liang, Y.-C. Liao, F.-Z. Shaw, D. W. Chang, C. P. Young, and H. Chiueh, "Closed-loop seizure control on epileptic rat models," J. Neural Eng., vol. 8, no. 4, p. 045001, 2011.
20. T.-J. Chen, C. J. , S.-T. Chang, H. Chiueh, S.-F. Liang, Y.-C. Hsu, and T.-C. Chien, "Ahardware implementation of real-time epileptic seizure detector on FPGA," in Proc. IEEE Biomed. Circuits Syst. Conf., Nov. 2011, pp. 25-28.
21. C.-P. Young, S.-F. Liang, D.-W. Chang, Y.-C. Liao, F.-Z. Shaw, and C.-H. Hsieh, "A portable wireless online closed-loop seizure controller in freely moving rats," IEEE Trans. Instrum. Meas., vol. 60, no. 2, pp. 513-521, Feb. 2011.
22. S. M. Pincus, "Approximate entropy as a measure of system complexity," Natl. Acad. Sci. USA, vol. 88, no. 6, pp. 2297-301, 1991. (Pubitemid 21916403)
23. M. Altaf, J. Tillak, Y. Kifle, and J. Yoo, "A 1.83 J/classification nonlinear support-vector-machine-based patient-specific seizure classification SoC," in IEEE Int. Solid-State Circuits Conf. Dig. Tech. Papers, Feb. 2013, pp. 100-101.
24. N. Verma, A. Shoeb, J. Bohorquez, J. Dawson, J. Guttag, and A. P. Chandrakasan, "A micro-power EEG acquisition SoC with integrated feature extraction processsor for chronic seizure detection system," IEEE J. Solid-State Circuits, vol. 45, no. 4, pp. 804-816, Jan. 2010.
25. S. Liang, W. Chang, and H. Chiueh, "EEG-based absence seizure detection methods," in Proc. Int. Joint Conf. Neural Networks, July 2010, pp. 1-4.
26. M. Sawan, F. Mounaim, and G. Lesbros, "Wireless monitoring of electrode- tissues interfaces for long term characterization," Analog Integr. Circuits Signal Process., vol. 55, no. 1, pp. 103-114, Apr. 2008.
27. M.-D. Ker, S.-L. Chen, and C.-S. Tsai, "Design of charge pump circuit with consideration of gate oxide reliability in low-voltage CMOS process," IEEE J. Solid-State Circuits, vol. 41, no. 5, pp. 1100-1107, May 2006.
28. G. Palumbo, D. Pappalardo, and M. Gaibotti, "Charge-pump circuits: power-consumption optimization," IEEE Trans. Circuits Syst. I, Fundam. Appl. Theory, vol. 49, no. 11, pp. 1535-1542, Nov. 2002. (Pubitemid 35426958)
29. C.Wang, C. Hsu, and Y. Liu, "A 1/2 VDD to 3 VDD bidirectional I/O buffer with a dynamic gate bias generator," IEEE Trans. Circuits Syst. I, Reg. Papers, vol. 57, no. 7, pp. 1642-1653, Jul. 2010.
30. F.-Z. Shaw, Y.-F. Liao, R.-F. Chen, Y.-H. Huang, and R. C. S. Lin, "The zona incerta modulates spontaneous spike-wave discharges in the rat," J. Neurophysiol., vol. 109, no. 10, pp. 2505-2516, 2013.
31. L.-C. Liu, M.-H. Ho, and C.-Y. Wu, "A medradio-band low-energyper- bit CMOS OOK transceiver for implantable medical devices," in Proc. Biomed. Circuits Syst. Conf., Nov. 2011, pp. 153-156.
32. C.-W. Chou, L.-C. Liu, and C.-Y. Wu, "A MedRadio-band low-energy- per-bit 4-Mbps CMOS OOK receiver for implantable medical devices," in Proc. 35th Annu. Int. Conf. IEEE Eng. Med. Biol. Soc., Jul. 2013, pp. 5171-5174.
33. S. Guo and H. Lee, "An efficiency-enhanced CMOS rectifier with unbalanced- biased comparators for transcutaneous powered high-current implants," IEEE J. Solid-State Circuits, vol. 44, no. 6, pp. 1796-1804, Jun. 2009.
34. J. Ramirez-Angulo, R. G. Garvajal, A. Torralba, J. Galan, A. P. VegaLeal, and J. Tombs, "The flipped voltage follower: A useful cell for low-voltage low-power circuit design," in Proc. IEEE Int. Symp. Circuits Syst., May 2002, vol. 3, pp. 615-618.
35. F.-Z. Shaw, "7-12 Hz high-voltage rhythmic spike discharges in rats evaluated by antiepileptic drugs and flicker stimulation," J. Neurophysiol., vol. 97, no. 1, pp. 238-247, 2007. (Pubitemid 46150786)
36. F.-Z. Shaw, "Is spontaneous high-voltage rhythmic spike discharge in Long Evans rats an absence-like seizure activity?," J. Neurophysiol., vol. 91, no. 1, pp. 63-77, 2004. (Pubitemid 38084354)
37. F.-Z. Shaw and Y.-F. Liao, "Relation between activities of the cortex and vibrissae muscle during high-voltage rhythmic spike discharges in rats," J. Neurophysiol., vol. 93, no. 5, pp. 2435-2448, 2005. (Pubitemid 40570829)
38. F.-Z. Shaw, S.-Y. Lee, and T.-H. Chiu, "Modulation of somatosensory evoked potential during wake-sleep states and spike-wave discharge in the rat," Sleep, vol. 29, no. 3, pp. 285-293, 2006. (Pubitemid 44019950)
39. H.-Y. Huang, H.-W. Lee, S.-D. Chen, and F.-Z. Shaw, "Lamotrigine ameliorates seizures and psychiatric comorbidity in a rat model of spontaneous absence epilepsy," Epilepsia, vol. 53, no. 11, pp. 2005-2014, 2012.
40. F.-Z. Shaw, S.-H. Chuang, K.-R. Shieh, and Y.-J. Wang, "Depressionand anxiety-like behaviors of a rat model with absence epileptic discharges," Neurosci., vol. 160, no. 2, pp. 382-393, 2009.
41. S.-D. Chen, K.-H. Yeh, Y.-H. Huang, and F.-Z. Shaw, "Effects of intracranial administration of ethosuximide in rats with spontaneous or pentylenetetrazol-induced spike-wave discharges," Epilepsia, vol. 52, no. 7, pp. 1311-1318, 2011.
42. P. O. Polack and S. Charpier, "Intracellular activity of cortical and thalamic neurons during high-voltage rhythmic spike discharge in Long- Evans rats in vivo," J. Physiol., vol. 571, no. 2, pp. 461-476, 2006.