메뉴 건너뛰기




Volumn 31, Issue 28, 2013, Pages 3549-3556

Allogeneic hematopoietic stem-cell transplantation for acute myeloid leukemia in remission: Comparison of intravenous busulfan plus cyclophosphamide (Cy) versus total-body irradiation plus cy as conditioning regimen-A report from the acute leukemia working party of theeuropean group for blood and marrow transplantation

(18)  Nagler, Arnon a   Rocha, Vanderson b   Labopin, Myriam c   Unal, Ali g   Ben Othman, Tarek h   Campos, Antonio i   Volin, Liisa j   Poire, Xavier k   Aljurf, Mahmoud l   Masszi, Tamás m   Socie, Gerard d   Sengelov, Henrik n   Michallet, Mauricette e   Passweg, Jakob o   Veelken, Hendrik p   Yakoub Agha, Ibrahim f   Shimoni, Avichai a   Mohty, Mohamad c  


Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; ANTINEOPLASTIC AGENT;

EID: 84891601014     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.48.8114     Document Type: Article
Times cited : (136)

References (37)
  • 1
    • 42949142189 scopus 로고    scopus 로고
    • Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
    • Schlenk RF, Dohner K, Krauter J, et al: Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 358: 1909-1918, 2008
    • (2008) N Engl J Med 358 , pp. 1909-1918
    • Schlenk, R.F.1    Dohner, K.2    Krauter, J.3
  • 2
    • 67049164836 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: Systematic review and meta-analysis of prospective clinical trials
    • Koreth J, Schlenk R, Kopecky KJ, et al: Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: Systematic review and meta-analysis of prospective clinical trials. JAMA 301:2349-2361, 2009
    • (2009) JAMA , vol.301 , pp. 2349-2361
    • Koreth, J.1    Schlenk, R.2    Kopecky, K.J.3
  • 3
    • 34247325560 scopus 로고    scopus 로고
    • Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: Benefits for whom?
    • Cornelissen JJ, van Putten WL, Verdonck LF, et al: Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: Benefits for whom? Blood 109:3658-3666, 2007
    • (2007) Blood , vol.109 , pp. 3658-3666
    • Cornelissen, J.J.1    Van Putten, W.L.2    Verdonck, L.F.3
  • 4
    • 0016398260 scopus 로고
    • Bonemarrow transplantation for hematologic neoplasia in 16 patients with identical twins
    • Fefer A, Einstein AB, Thomas ED, et al: Bonemarrow transplantation for hematologic neoplasia in 16 patients with identical twins. N Engl J Med 290:1389-1393, 1974
    • (1974) N Engl J Med , vol.290 , pp. 1389-1393
    • Fefer, A.1    Einstein, A.B.2    Thomas, E.D.3
  • 5
    • 0023574955 scopus 로고
    • Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen
    • Tutschka PJ, Copelan EA, Klein JP: Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen. Blood 70:1382-1388, 1987
    • (1987) Blood , vol.70 , pp. 1382-1388
    • Tutschka, P.J.1    Copelan, E.A.2    Klein, J.P.3
  • 6
    • 0021035301 scopus 로고
    • Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide
    • Santos GW, Tutschka PJ, Brookmeyer R, et al: Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. N Engl J Med 309:1347-1353, 1983
    • (1983) N Engl J Med , vol.309 , pp. 1347-1353
    • Santos, G.W.1    Tutschka, P.J.2    Brookmeyer, R.3
  • 7
    • 0030824872 scopus 로고    scopus 로고
    • Busulfan/cyclophosphamide in volunteer unrelated donor (VUD) BMT: Excellent feasibility and low incidence of treatment-related toxicity
    • Bertz H, Potthoff K, Mertelsmann R, et al: Busulfan/cyclophosphamide in volunteer unrelated donor (VUD) BMT: Excellent feasibility and low incidence of treatment-related toxicity. Bone Marrow Transplant 19:1169-1173, 1997
    • (1997) Bone Marrow Transplant , vol.19 , pp. 1169-1173
    • Bertz, H.1    Potthoff, K.2    Mertelsmann, R.3
  • 8
    • 0026762652 scopus 로고
    • Allogeneic bone marrow transplantation for acute myeloid leukemia in first remission: A randomized trial of a busulfan-Cytoxan versus Cytoxan-total body irradiation as preparative regimen-A report from the Group d'Etudes de la Greffe de Moelle Osseuse
    • Blaise D, Maraninchi D, Archimbaud E, et al: Allogeneic bone marrow transplantation for acute myeloid leukemia in first remission: A randomized trial of a busulfan-Cytoxan versus Cytoxan-total body irradiation as preparative regimen-A report from the Group d'Etudes de la Greffe de Moelle Osseuse. Blood 79:2578-2582, 1992
    • (1992) Blood , vol.79 , pp. 2578-2582
    • Blaise, D.1    Maraninchi, D.2    Archimbaud, E.3
  • 9
    • 0028210717 scopus 로고
    • A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: A report from the Nordic Bone Marrow Transplantation Group
    • Ringdén O, Ruutu T, Remberger M, et al: A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: A report from the Nordic Bone Marrow Transplantation Group. Blood 83:2723-2730, 1994
    • (1994) Blood , vol.83 , pp. 2723-2730
    • Ringdén, O.1    Ruutu, T.2    Remberger, M.3
  • 10
    • 0036456695 scopus 로고    scopus 로고
    • Comparison of outcome following allogeneic bone marrow transplantation with cyclophosphamide-total body irradiation versus busulphan-cyclophosphamide conditioning regimens for acute myelogenousleukaemia in first remission
    • Litzow MR, Pérez WS, Klein JP, et al: Comparison of outcome following allogeneic bone marrow transplantation with cyclophosphamide-total body irradiation versus busulphan-cyclophosphamide conditioning regimens for acute myelogenousleukaemia in first remission. Br J Haematol 119: 1115-1124, 2002
    • (2002) Br J Haematol , vol.119 , pp. 1115-1124
    • Litzow, M.R.1    Pérez, W.S.2    Klein, J.P.3
  • 11
    • 0035895063 scopus 로고    scopus 로고
    • Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: Long-term follow-up of 4 randomized studies
    • Socié G, Clift RA, Blaise D, et al: Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: Long-term follow-up of 4 randomized studies. Blood 98:3569-3574, 2001
    • (2001) Blood , vol.98 , pp. 3569-3574
    • Socié, G.1    Clift, R.A.2    Blaise, D.3
  • 12
    • 0033120367 scopus 로고    scopus 로고
    • Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: Long-term results of a randomized trial in allogeneic marrow recipients with leukemia-Nordic Bone Marrow Transplantation Group
    • Ringdén O, Remberger M, Ruutu T, et al: Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: Long-term results of a randomized trial in allogeneic marrow recipients with leukemia-Nordic Bone Marrow Transplantation Group. Blood 93:2196-2201, 1999
    • (1999) Blood , vol.93 , pp. 2196-2201
    • Ringdén, O.1    Remberger, M.2    Ruutu, T.3
  • 13
    • 0031667489 scopus 로고    scopus 로고
    • Survival, disease-free survival and adverse effects of conditioning for allogeneic bone marrow transplantation with busulfan/cyclophosphamide vs. Total body irradiation: A meta-analysis
    • Hartman AR, Williams SF, Dillon JJ: Survival, disease-free survival and adverse effects of conditioning for allogeneic bone marrow transplantation with busulfan/cyclophosphamide vs. total body irradiation: A meta-analysis. Bone Marrow Transplant 22:439-443, 1998
    • (1998) Bone Marrow Transplant , vol.22 , pp. 439-443
    • Hartman, A.R.1    Williams, S.F.2    Dillon, J.J.3
  • 14
    • 74949114120 scopus 로고    scopus 로고
    • Total body irradiation plus cyclophosphamide versus busulphan with cyclophosphamide as conditioning regimen for patients with leukemia undergoing allogeneic stem cell transplantation: A meta-analysis
    • Shi-Xia X, Xian-Hua T, Hai-Qin X, et al: Total body irradiation plus cyclophosphamide versus busulphan with cyclophosphamide as conditioning regimen for patients with leukemia undergoing allogeneic stem cell transplantation: A meta-analysis. Leuk Lymphoma 51:50-60, 2010
    • (2010) Leuk Lymphoma , vol.51 , pp. 50-60
    • Shi-Xia, X.1    Xian-Hua, T.2    Hai-Qin, X.3
  • 15
    • 0030770990 scopus 로고    scopus 로고
    • High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients
    • Ljungman P, Hassan M, Békássy AN, et al: High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients. Bone Marrow Transplant 20:909-913, 1997
    • (1997) Bone Marrow Transplant , vol.20 , pp. 909-913
    • Ljungman, P.1    Hassan, M.2    Békássy, A.N.3
  • 16
    • 0029057117 scopus 로고
    • Graft-rejection and toxicity following bone marrow transplantation in relation to busulfan pharmacokinetics
    • Slattery JT, Sanders JE, Buckner CD, et al: Graft-rejection and toxicity following bone marrow transplantation in relation to busulfan pharmacokinetics. Bone Marrow Transplant 16:31-42, 1995
    • (1995) Bone Marrow Transplant , vol.16 , pp. 31-42
    • Slattery, J.T.1    Sanders, J.E.2    Buckner, C.D.3
  • 17
    • 13344259305 scopus 로고    scopus 로고
    • Association of busulfan area under the curve with venoocclusive disease following BMT
    • Dix SP, Wingard JR, Mullins RE, et al: Association of busulfan area under the curve with venoocclusive disease following BMT. Bone Marrow Transplant 17:225-230, 1996
    • (1996) Bone Marrow Transplant , vol.17 , pp. 225-230
    • Dix, S.P.1    Wingard, J.R.2    Mullins, R.E.3
  • 18
    • 0024345093 scopus 로고
    • Pharmacokinetics of busulfan: Correlation with veno-occlusive disease in patients undergoing bone marrow transplantation
    • Grochow LB, Jones RJ, Brundrett RB, et al: Pharmacokinetics of busulfan: Correlation with veno-occlusive disease in patients undergoing bone marrow transplantation. Cancer Chemother Pharmacol 25:55-61, 1989
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 55-61
    • Grochow, L.B.1    Jones, R.J.2    Brundrett, R.B.3
  • 19
    • 78651346532 scopus 로고    scopus 로고
    • Comparative analysis of BU and CY versus CY and TBI in full intensity unrelated marrow donor transplantation for AML, CML and myelodysplasia
    • Uberti JP, Agovi MA, Tarima S, Comparative analysis of BU and CY versus CY and TBI in full intensity unrelated marrow donor transplantation for AML, CML and myelodysplasia. Bone Marrow Transplant 46:34-43, 2011
    • (2011) Bone Marrow Transplant , vol.46 , pp. 34-43
    • Uberti, J.P.1    Agovi, M.A.2    Tarima, S.3
  • 20
    • 0037562931 scopus 로고    scopus 로고
    • Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: Myeloablation with reduced toxicity
    • Shimoni A, Bielorai B, Toren A, et al: Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: Myeloablation with reduced toxicity. Exp Hematol 31:428-434, 2003
    • (2003) Exp Hematol , vol.31 , pp. 428-434
    • Shimoni, A.1    Bielorai, B.2    Toren, A.3
  • 21
    • 31444444950 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: The role of dose intensity
    • Shimoni A, Hardan I, Shem-Tov N, et al: Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: The role of dose intensity. Leukemia 20:322-328, 2006
    • (2006) Leukemia , vol.20 , pp. 322-328
    • Shimoni, A.1    Hardan, I.2    Shem-Tov, N.3
  • 22
    • 34548769294 scopus 로고    scopus 로고
    • Comparison between two fludarabine-based reducedintensity conditioning regimens before allogeneic hematopoietic stem-cell transplantation: Fludarabine/ melphalan is associated with higher incidence of acute graft-versus-host disease and non-relapse mortality and lower incidence of relapse than fludarabine/busulfan
    • Shimoni A, Hardan I, Shem-Tov N, et al: Comparison between two fludarabine-based reducedintensity conditioning regimens before allogeneic hematopoietic stem-cell transplantation: Fludarabine/ melphalan is associated with higher incidence of acute graft-versus-host disease and non-relapse mortality and lower incidence of relapse than fludarabine/busulfan. Leukemia 21:2109-2116, 2007
    • (2007) Leukemia , vol.21 , pp. 2109-2116
    • Shimoni, A.1    Hardan, I.2    Shem-Tov, N.3
  • 23
    • 0036400369 scopus 로고    scopus 로고
    • Intravenous versus oral busulfan as part of a busulfan/ cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: Decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality
    • Kashyap A, Wingard J, Cagnoni P, et al: Intravenous versus oral busulfan as part of a busulfan/ cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: Decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality. Biol Blood Marrow Transplant 8:493-500, 2002
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 493-500
    • Kashyap, A.1    Wingard, J.2    Cagnoni, P.3
  • 24
    • 23244433213 scopus 로고    scopus 로고
    • Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs. Oral busulfan in adults conditioned with busulfanα cyclophosphamide for allogeneic bone marrow transplantation
    • Lee JH, Choi SJ, Lee JH, et al: Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs. oral busulfan in adults conditioned with busulfanα cyclophosphamide for allogeneic bone marrow transplantation. Ann Hematol 84:321-330, 2005
    • (2005) Ann Hematol , vol.84 , pp. 321-330
    • Lee, J.H.1    Choi, S.J.2    Lee, J.H.3
  • 26
    • 0027478056 scopus 로고
    • Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: A cohort study of 355 patients
    • McDonald GB, Hinds MS, Fisher LD, et al: Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: A cohort study of 355 patients. Ann Intern Med 118:255-267, 1993
    • (1993) Ann Intern Med , vol.118 , pp. 255-267
    • McDonald, G.B.1    Hinds, M.S.2    Fisher, L.D.3
  • 27
    • 79956198240 scopus 로고    scopus 로고
    • Linearity and stability of intravenous busulfan pharmacokinetics and the role of glutathione in busulfan elimination
    • Almog S, Kurnik D, Shimoni A, et al: Linearity and stability of intravenous busulfan pharmacokinetics and the role of glutathione in busulfan elimination. Biol Blood Marrow Transplant 17:117-123, 2011
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 117-123
    • Almog, S.1    Kurnik, D.2    Shimoni, A.3
  • 28
    • 0034567061 scopus 로고    scopus 로고
    • Acute safety and pharmacokinetics of intravenous busulfan when used with oral busulfan and cyclophosphamide as pretransplantation conditioning therapy: A phase i study
    • Andersson BS, Madden T, Tran HT, et al: Acute safety and pharmacokinetics of intravenous busulfan when used with oral busulfan and cyclophosphamide as pretransplantation conditioning therapy: A phase I study. Biol Blood Marrow Transplant 6:548-554, 2000
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 548-554
    • Andersson, B.S.1    Madden, T.2    Tran, H.T.3
  • 29
    • 43449126806 scopus 로고    scopus 로고
    • Once daily i.V. Busulfan and fludarabine (i.V. Bu-Flu) compares favorably with I.V. Busulfan and cyclophosphamide (I.V BuCy2) as pretransplant conditioning therapy in AML/MDS
    • Andersson BS, de Lima M, Thall PF, et al: Once daily i.v. busulfan and fludarabine (i.v. Bu-Flu) compares favorably with i.v. busulfan and cyclophosphamide (i.v BuCy2) as pretransplant conditioning therapy in AML/MDS. Biol Blood Marrow Transplant 14:672-684, 2008
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 672-684
    • Andersson, B.S.1    De Lima, M.2    Thall, P.F.3
  • 30
    • 3242810563 scopus 로고    scopus 로고
    • Once-daily intravenous busulfan and fludarabine: Clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS
    • de Lima M, Couriel D, Thall PF, et al: Once-daily intravenous busulfan and fludarabine: Clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS. Blood 104:857-864, 2004
    • (2004) Blood , vol.104 , pp. 857-864
    • De Lima, M.1    Couriel, D.2    Thall, P.F.3
  • 31
    • 80052576601 scopus 로고    scopus 로고
    • Myeloablative reduced-toxicity i.V. Busulfan-fludarabine and allogeneic hematopoietic stem cell transplant for patients with acute myeloid leukemia or myelodysplastic syndrome in the sixth through eighth decades of life
    • Alatrash G, de Lima M, Hamerschlak N, et al: Myeloablative reduced-toxicity i.v. busulfan-fludarabine and allogeneic hematopoietic stem cell transplant for patients with acute myeloid leukemia or myelodysplastic syndrome in the sixth through eighth decades of life. Biol Blood Marrow Transplant 17:1490-1496, 2011
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 1490-1496
    • Alatrash, G.1    De Lima, M.2    Hamerschlak, N.3
  • 32
    • 68049107377 scopus 로고    scopus 로고
    • Reduced-toxicity conditioning therapy with allogeneic stem cell transplantation for acute leukemia
    • Andersson BS, de Lima M, Thall PF, et al: Reduced-toxicity conditioning therapy with allogeneic stem cell transplantation for acute leukemia. Curr Opin Oncol 21:S11-S15, 2009 (suppl 1)
    • (2009) Curr Opin Oncol , vol.21 , pp. S11-S15
    • Andersson, B.S.1    De Lima, M.2    Thall, P.F.3
  • 33
    • 0036205591 scopus 로고    scopus 로고
    • Conditioning therapy with intravenous busulfan and cyclophosphamide (IV BuCy2) for hematologic malignancies prior to allogeneic stem cell transplantation: A phase II study
    • Andersson BS, Kashyap A, Gian V, et al: Conditioning therapy with intravenous busulfan and cyclophosphamide (IV BuCy2) for hematologic malignancies prior to allogeneic stem cell transplantation: A phase II study. Biol Blood Marrow Transplant 8:145-154, 2002
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 145-154
    • Andersson, B.S.1    Kashyap, A.2    Gian, V.3
  • 34
    • 33644548575 scopus 로고    scopus 로고
    • Matched pairs analysis of IV vs. PO Busulfan as a conditioning agent prior to transplantation
    • suppl 1; abstr 349
    • Sobocinski K, Thall PF, Bekele BN, et al: Matched pairs analysis of IV vs. PO Busulfan as a conditioning agent prior to transplantation. Blood 104, 2004 (suppl 1; abstr 349)
    • (2004) Blood , vol.104
    • Sobocinski, K.1    Thall, P.F.2    Bekele, B.N.3
  • 35
    • 0033917097 scopus 로고    scopus 로고
    • Pathogenesis of acute graft-versushost disease: Cytokines and cellular effectors
    • Ferrara JL: Pathogenesis of acute graft-versushost disease: Cytokines and cellular effectors. J Hematother Stem Cell Res 9:299-306, 2000
    • (2000) J Hematother Stem Cell Res , vol.9 , pp. 299-306
    • Ferrara, J.L.1
  • 36
    • 84863371821 scopus 로고    scopus 로고
    • Plasma biomarkers of lower gastrointestinal and liver acute GVHD
    • Harris AC, Ferrara JL, Braun TM, et al: Plasma biomarkers of lower gastrointestinal and liver acute GVHD. Blood 119:2960-2963, 2012
    • (2012) Blood , vol.119 , pp. 2960-2963
    • Harris, A.C.1    Ferrara, J.L.2    Braun, T.M.3
  • 37
    • 84863963063 scopus 로고    scopus 로고
    • Long-term complications and side effects after allogeneic hematopoietic stem cell transplantation: An update
    • Mohty B, Mohty M: Long-term complications and side effects after allogeneic hematopoietic stem cell transplantation: An update. Blood Cancer J 1:1-4, 2011
    • (2011) Blood Cancer J , vol.1 , pp. 1-4
    • Mohty, B.1    Mohty, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.