Sympathomimetic syndrome, choreoathetosis, and acute kidney injury following "bath salts" injection

Clinical Nephrology

Volumn 81, Issue 1, 2014, Pages 63-66

  Sutamtewagul, Grerk ^a   Sood, Vineeta ^a   Nugent, Kenneth ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

Acute kidney injury; Bath salts; Choreoathetosis; Dopamine

Indexed keywords

BATH SALT; CREATINE KINASE; DESIGNER DRUG; HALOPERIDOL; LORAZEPAM; STREET DRUG; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ADULT; AGITATION; ARTICLE; AUTONOMIC NEUROPATHY; BLURRED VISION; CASE REPORT; CHOREOATHETOSIS; DISORIENTATION; EYE PAIN; GUSTATORY HALLUCINATION; HUMAN; HYPERHIDROSIS; HYPERTENSION; LEUKOCYTOSIS; LOSS OF APPETITE; MALE; METALLIC TASTE; OLFACTORY HALLUCINATION; PALLIATIVE THERAPY; SOMNOLENCE; SWEATING; SYMPATHOMIMETIC SYNDROME; TACHYCARDIA; TACHYPNEA; UREA NITROGEN BLOOD LEVEL;

ACUTE KIDNEY INJURY; ADULT; ATHETOSIS; BENZODIOXOLES; CATECHOLAMINES; CENTRAL NERVOUS SYSTEM STIMULANTS; CHOREA; DESIGNER DRUGS; HUMANS; INJECTIONS; MALE; METHAMPHETAMINE; PYRROLIDINES; SYNDROME;

EID: 84891590083     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/CN107559     Document Type: Article

References (15)

1. Centers for Disease Control and Prevention (CDC). Emergency department visits after use of a drug sold as "bath salts"-Michigan, November 13, 2010-March 31, 2011. MMWR Morb Mortal Wkly Rep. 2011; 60: 624-627.
2. Meyer MR, Du P, Schuster F, Maurer HH. Studies on the metabolism of the a-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV)in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by GC-MS. J Mass Spectrom. 2010; 45: 1426-1442. doi:10.1002/jms.1859
3. Fauquet JP, Morel E, Demarty C, Rapin JR. Role des Catecholamines centrales dans l'activite psychostimulante de la pyrovelerone. Arch int Pharmacodyn 1976; 224: 325-337.
4. Servin A, Fauquet JP, Jacquot C, Rapin JR. Effects of pyrovalerone on peripheral noradrenergic mechanisms. Biochem Pharmacol. 1978; 27: 1693-1694. doi:10.1016/0006-2952(78)90180-6
5. Antonowicz JL, Metzger AK, Ramanujan SL. Paranoid psychosis induced by consumption of methylenedioxypyrovalerone: two cases. Gen Hosp Psychiatry. 2011; 33: 640. e5-6.
6. Penders TM, Gestring R. Hallucinatory delirium following use of MDPV: "Bath Salts. Gen Hosp Psychiatry. 2011; 33: 525-526.
7. Kriikku P, Wilhelm L, Schwarz O, Rintatalo J. New designer drug of abuse: 3,4-Methylenedioxypyrovalerone (MDPV). Findings from apprehended driver in Finland. Forensic Sci Int. 2011; 210: 195-200. doi:10.1016/j. forsciint.2011.03.015
8. Ross EA, Watson M, Goldberger B. "Bath salts" intoxication. N Engl J Med. 2011; 365: 967-968. doi:10.1056/NEJMc1107097
9. Methylenedioxypyrovalerone (MDPV). 2011. (Accessed Nov 12, 2011, 2011, at http://www.deadiversion.usdoj.gov/drugs_concern/mdpv.pdf.).
10. Adebamiro A, Perazella MA. Recurrent acute kidney injury following bath salts intoxication. Am J Kidney Dis. 2012; 59: 273-275. doi:10.1053/j. ajkd.2011.10.012
11. Steinhausen M, Weis S, Fleming J, Dussel R, Parekh N. Responses of in vivo renal microvessels to dopamine. Kidney Int. 1986; 30: 361-370. doi:10.1038/ki.1986.193
12. Lauschke A, Teichgräber UK, Frei U, Eckardt KU. 'Low-dose' dopamine worsens renal perfusion in patients with acute renal failure. Kidney Int. 2006; 69: 1669-1674. doi:10.1038/sj. ki.5000310
13. Cronin RE, Erickson AM, de Torrente A, McDonald KM, Schrier RW. Norepinephrine-induced acute renal failure: a reversible ischemic model of acute renal failure. Kidney Int. 1978; 14: 187-190. doi:10.1038/ki.1978.106
14. Ryan MJ, Tuttle KR. Elevations in serum creatinine with RAAS blockade: why isn't it a sign of kidney injury? Curr Opin Nephrol Hypertens. 2008; 17: 443-449. doi:10.1097/MNH.0b013e32830a9606
15. McCann B, Hunter R, McCann J. Cocaine/heroin induced rhabdomyolysis and ventricular fibrillation. Emerg Med J. 2002; 19: 264-265. doi:10.1136/emj.19.3.264