Clonal heterogeneity as detected by metaphase karyotyping is an indicator of poor prognosis in acute myeloid leukemia

Journal of Clinical Oncology

Volumn 31, Issue 31, 2013, Pages 3898-3905

  Bochtler, Tilmann ^a,b   Stol̈zel, Friedrich ^c   Heilig, Christoph E ^a   Kunz, Christina ^b   Mohr, Brigitte ^c   Jauch, Anna ^a   Janssen, Johannes W G ^a   Kramer, Michael ^c   Benner, Axel ^a   Bornhaüser, Martin ^c   Ho, Anthony D ^a   Ehninger, Gerhard ^c   Schaich, Markus ^c   Kram̈er, Alwin ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CORE BINDING FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER PROGNOSIS; CANCER THERAPY; CLONAL EVOLUTION; CLONE HETEROGENEITY; CONSOLIDATION CHEMOTHERAPY; CONTROLLED STUDY; CYTOGENETICS; EVENT FREE SURVIVAL; FEMALE; GENETIC HETEROGENEITY; HUMAN; KARYOTYPING; LEUKEMIA REMISSION; MAJOR CLINICAL STUDY; MALE; METAPHASE; MULTICENTER STUDY; MULTIMODALITY CANCER THERAPY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; VERY ELDERLY; CHROMOSOME ABERRATION; GENETICS; LEUKEMIA, MYELOID, ACUTE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY (TOPIC); PROCEDURES; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT OUTCOME; YOUNG ADULT; METHODOLOGY;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHROMOSOME ABERRATIONS; FEMALE; HUMANS; KARYOTYPING; LEUKEMIA, MYELOID, ACUTE; MALE; METAPHASE; MIDDLE AGED; MULTICENTER STUDIES AS TOPIC; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84891589611     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.50.7921     Document Type: Article

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