Prenatal diethylstilbestrol exposure and risk of uterine leiomyomata in the nurses' health study II

American Journal of Epidemiology

Volumn 179, Issue 2, 2014, Pages 186-191

  Mahalingaiah, Shruthi ^a   Hart, Jaime E ^b,c   Wise, Lauren A ^d   Terry, Kathryn L ^b   Boynton Jarrett, Renée ^a   Missmer, Stacey A ^b,c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d BOSTON UNIVERSITY   (United States)

Author keywords

diethylstilbestrol; prospective cohort; uterine fibroid

Indexed keywords

DIETHYLSTILBESTROL;

CANCER; COHORT ANALYSIS; DISEASE INCIDENCE; ENDOCRINE DISRUPTOR; HAZARD ASSESSMENT; HEALTH RISK; HEALTH SURVEY; MULTIVARIATE ANALYSIS; SPATIOTEMPORAL ANALYSIS; WOMENS HEALTH;

ADULT; ARTICLE; CLINICAL TRIAL; FEMALE; FIRST TRIMESTER PREGNANCY; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; PREMENOPAUSE; PRENATAL DRUG EXPOSURE; PROPORTIONAL HAZARDS MODEL; UTERUS MYOMA;

DIETHYLSTILBESTROL; PROSPECTIVE COHORT; UTERINE FIBROID;

ADULT; COHORT STUDIES; DIETHYLSTILBESTROL; FEMALE; HUMANS; LEIOMYOMA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PRENATAL EXPOSURE DELAYED EFFECTS; PROPORTIONAL HAZARDS MODELS; QUESTIONNAIRES; UTERINE NEOPLASMS;

EID: 84891553113     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwt250     Document Type: Article

References (22)

1. Greenwald P, Barlow JJ, Nasca PC, et al. Vaginal cancer after maternal treatment with synthetic estrogens. N Engl J Med. 1971;285(7):390-392.
2. Wise LA, Palmer JR, Rowlings K, et al. Risk of benign gynecologic tumors in relation to prenatal diethylstilbestrol exposure. Obstet Gynecol. 2005;105(1):167-173.
3. Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, et al. Endocrine-disrupting chemicals: An Endocrine Society scientific statement. Endocr Rev. 2009;30(4):293-342.
4. Kaufman RH, Adam E, Hatch EE, et al. Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring. Obstet Gynecol. 2000;96(4):483-489.
5. Centers for Disease Control and Prevention. DES history. Atlanta, GA: Centers for Disease Control and Prevention; 2003. (http://www.cdc.gov/DES/ consumers/about/history.html). (Accessed May 10, 2013).
6. Baird DD, Newbold R. Prenatal diethylstilbestrol (DES) exposure is associated with uterine leiomyoma development. Reprod Toxicol. 2005;20(1):81-84.
7. D'Aloisio AA, Baird DD, DeRoo LA, et al. Association of intrauterine and early-life exposures with diagnosis of uterine leiomyomata by 35 years of age in the Sister Study. Environ Health Perspect. 2010;118(3):375-381.
8. D'Aloisio AA, Baird DD, DeRoo LA, et al. Early-life exposures and early-onset uterine leiomyomata in black women in the Sister Study. Environ Health Perspect. 2012; 120(3):406-412.
9. Baird DD, Dunson DB, Hill MC, et al. High cumulative incidence of uterine leiomyoma in black and white women: Ultrasound evidence. Am J Obstet Gynecol. 2003;188(1): 100-107.
10. Stewart EA. Uterine fibroids. Lancet. 2001;357(9252): 293-298.
11. Farquhar CM, Steiner CA. Hysterectomy rates in the United States 1990-1997. Obstet Gynecol. 2002;99(2):229-234.
12. Hoover RN, Hyer M, Pfeiffer RM, et al. Adverse health outcomes in women exposed in utero to diethylstilbestrol. N Engl J Med. 2011;365(14):1304-1314.
13. Marshall LM, Spiegelman D, Barbieri RL, et al. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol. 1997;90(6):967-973.
14. O'Reilly EJ, Mirzaei F, Forman MR, et al. Diethylstilbestrol exposure in utero and depression in women. Am J Epidemiol. 2010;171(8):876-882.
15. Missmer SA, Hankinson SE, Spiegelman D, et al. In utero exposures and the incidence of endometriosis. Fertil Steril. 2004;82(6):1501-1508.
16. Newbold RR. Cellular and molecular effects of developmental exposure to diethylstilbestrol: Implications for other environmental estrogens. Environ Health Perspect. 1995; 103(suppl 7):83-87.
17. Newbold RR, Moore AB, Dixon D. Characterization of uterine leiomyomas in CD-1 mice following developmental exposure to diethylstilbestrol (DES). Toxicol Pathol. 2002;30(5): 611-616.
18. Greathouse KL, Cook JD, Lin K, et al. Identification of uterine leiomyoma genes developmentally reprogrammed by neonatal exposure to diethylstilbestrol. Reprod Sci. 2008;15(8):765-778.
19. Newbold RR. Lessons learned from perinatal exposure to diethylstilbestrol. Toxicol Appl Pharmacol. 2004;199(2): 142-150.
20. Anderson OS, Nahar MS, Faulk C, et al. Epigenetic responses following maternal dietary exposure to physiologically relevant levels of bisphenol A. Environ Mol Mutagen. 2012;53(5): 334-342.
21. Tuomisto J, Tuomisto JT. Is the fear of dioxin cancer more harmful than dioxin? Toxicol Lett. 2012;210(3):338-344.
22. Bromer JG, Wu J, Zhou Y, et al. Hypermethylation of homeobox A10 by in utero diethylstilbestrol exposure: An epigenetic mechanism for altered developmental programming. Endocrinology. 2009;150(7):3376-3382. Development