Status epilepticus as a system disturbance: Is status epilepticus due to synchronization or desynchronization?

Epilepsia

Volumn 54, Issue SUPPL. 6, 2013, Pages 37-39

  Cash, Sydney S ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Action potential; Hypersynchronization; Scale; Seizure termination; Synaptic input

Indexed keywords

ACTION POTENTIAL; ARTICLE; EPILEPTIC DISCHARGE; EPILEPTIC STATE; HUMAN; MAGNETOENCEPHALOGRAPHY; MICROELECTRODE; NEUROPHYSIOLOGY; PRIORITY JOURNAL; SEIZURE; ANIMAL; ELECTROENCEPHALOGRAPHY PHASE SYNCHRONIZATION; HYPERSYNCHRONIZATION; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SCALE; SEIZURE TERMINATION; SYNAPTIC INPUT; STATUS EPILEPTICUS;

ACTION POTENTIAL; HYPERSYNCHRONIZATION; SCALE; SEIZURE TERMINATION; SYNAPTIC INPUT;

ACTION POTENTIALS; ANIMALS; ELECTROENCEPHALOGRAPHY PHASE SYNCHRONIZATION; HUMANS; NEURONS; STATUS EPILEPTICUS;

EID: 84891537470     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12273     Document Type: Article

References (15)

1. Bower MR, Stead M, Meyer FB, Marsh WR, Worrell GA. (2012) Spatiotemporal neuronal correlates of seizure generation in focal epilepsy. Epilepsia 53:807-816.
2. Ermentrout GB, Kopell N. (1998) Fine structure of neural spiking and synchronization in the presence of conduction delays. Proc Natl Acad Sci USA 95:1259-1264.
3. Garcia Dominguez L, Wennberg RA, Gaetz W, Cheyne D, Snead OC 3rd, Perez Velazquez JL. (2005) Enhanced synchrony in epileptiform activity? Local versus distant phase synchronization in generalized seizures. J Neurosci 25:8077-8084.
4. Gutkin BS, Ermentrout GB, Reyes AD. (2005) Phase-response curves give the responses of neurons to transient inputs. J Neurophysiol 94:1623-1635.
5. Jiruska P, de Curtis M, Jefferys JG, Schevon CA, Schiff SJ, Schindler K. (2013) Synchronization and desynchronization in epilepsy: Controversies and hypotheses. J Physiol 591(Pt 4):787-797.
6. Keller CJ, Truccolo W, Gale JT, Eskandar E, Thesen T, Carlson C, Devinsky O, Kuzniecky R, Doyle WK, Madsen JF, Schomer DL, Mehta AD, Brown EN, Hochberg LR, Ulbert I, Halgren E, Cash SS. (2010) Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex. Brain 133(Pt 6):1668-1681.
7. Kramer MA, Eden UT, Kolaczyk ED, Zepeda R, Eskandar EN, Cash SS. (2010) Coalescence and fragmentation of cortical networks during focal seizures. J Neurosci 30:10076-10085.
8. Kramer MA, Truccolo W, Eden UT, Lepage KQ, Hochberg LR, Eskandar EN, Madsen JR, Lee JW, Maheshwari A, Halgren E, Chu CJ, Cash SS. (2012) Human seizures self-terminate across spatial scales via a critical transition. Proc Natl Acad Sci USA 109:21116-21121.
9. Le Van Quyen M, Martinerie J, Navarro V, Baulac M, Varela FJ. (2001) Characterizing neurodynamic changes before seizures. J Clin Neurophysiol 18:191-208.
10. Netoff TI, Schiff SJ. (2002) Decreased neuronal synchronization during experimental seizures. J Neurosci 22:7297-7307.
11. Schindler K, Leung H, Elger CE, Lehnertz K. (2007) Assessing seizure dynamics by analysing the correlation structure of multichannel intracranial EEG. Brain 130(Pt 1):65-77.
12. Schindler KA, Bialonski S, Horstmann MT, Elger CE, Lehnertz K. (2008) Evolving functional network properties and synchronizability during human epileptic seizures. Chaos 18:033119.
13. Treiman DM, Walton NY, Kendrick C. (1990) A progressive sequence of electroencephalographic changes during generalized convulsive status epilepticus. Epilepsy Res 5:49-60.
14. Truccolo W, Donoghue JA, Hochberg LR, Eskandar EN, Madsen JR, Anderson WS, Brown EN, Halgren E, Cash SS. (2011) Single-neuron dynamics in human focal epilepsy. Nat Neurosci 14:635-641.
15. Wendling F, Bartolomei F, Bellanger JJ, Bourien J, Chauvel P. (2003) Epileptic fast intracerebral EEG activity: Evidence for spatial decorrelation at seizure onset. Brain 126(Pt 6):1449-1459.