High nasal burden of methicillin-resistant staphylococcus aureus increases risk of invasive disease

Journal of Clinical Microbiology

Volumn 52, Issue 1, 2014, Pages 312-314

  Datta, Rupak ^a   Shah, Atia ^b   Huang, Susan S ^a,b   Cui, Eric ^a,b   Nguyen, Vinh ^c   Welbourne, Susan J ^b   Quan, Kathleen A ^b   Thrupp, Lauri ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c 5226 Donald Bren Hall   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LINEZOLID; PSEUDOMONIC ACID; TIGECYCLINE; VANCOMYCIN;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BACTERIUM DETECTION; BLOOD CULTURE; COHORT ANALYSIS; DISEASE COURSE; FEMALE; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NOSE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TEACHING HOSPITAL; THROAT CULTURE; URINE CULTURE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL LOAD; CARRIER STATE; COHORT STUDIES; FEMALE; HUMANS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; NASAL MUCOSA; PREVALENCE; RETROSPECTIVE STUDIES; RISK ASSESSMENT; STAPHYLOCOCCAL INFECTIONS; YOUNG ADULT;

EID: 84891535598     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.01606-13     Document Type: Article

References (25)

1. Kluytmans J, van Belkum A, Verbrugh H. 1997. Nasal carriage of Staphylococcus aureus: Epidemiology, underlying mechanisms, and associated risks. Clin. Microbiol. Rev. 10:505-520.
2. Wertheim HF, Vos MC, Ott A, van Belkum A, Voss A, Kluytmans JA, van Keulen PH, Vandenbroucke-Grauls CM, Meester MH, Verbrugh HA. 2004. Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers. Lancet 364:703-705. http://dx.doi.org/10.1016/S0140-6736(04) 16897-9.
3. Wertheim HF, Melles DC, Vos MC, van Leeuwen W, van Belkum A, Verbrugh HA, Nouwen JL. 2005. The role of nasal carriage in Staphylococcus aureus infections. Lancet Infect. Dis. 5:751-762. http://dx.doi.org/10.1016/S1473- 3099(05)70295-4.
4. Seybold U, Schubert S, Bogner JR, Hogardt M. 2011. Staphylococcus aureus infection following nasal colonization: An approach to rapid risk stratification in a university healthcare system. J. Hosp. Infect. 79:297-301. http://dx.doi.org/10.1016/j.jhin.2011.08.017.
5. Asensio A, Guerrero A, Quereda C, Lizán M, Martinez-Ferrer M. 1996. Colonization and infection with methicillin-resistant Staphylococcus aureus: Associated factors and eradication. Infect. Control Hosp. Epidemiol. 17:20-28. http://dx.doi.org/10.1086/647184.
6. Pujol M, Pena C, Pallares R, Ayats J, Ariza J, Gudiol F. 1994. Risk factors for nosocomial bacteremia due to methicillin-resistant Staphylococcus aureus. Eur. J. Clin. Microbiol. Infect. Dis. 13:96-102. http://dx.doi.org/10. 1007/BF02026134.
7. Davis KA, Stewart JJ, Crouch HK, Florez CE, Hospenthal DR. 2004. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent MRSA infection. Clin. Infect. Dis. 39:776-782. http://dx.doi.org/10.1086/422997.
8. Huang SS, Hinrichsen VL, Datta R, Spurchise L, Miroshnik I, Nelson K, Platt R. 2011. Methicillin-resistant Staphylococcus aureus infection and hospitalization in high-risk patients in the year following detection. PLoS One 6:e24340. http://dx.doi.org/10.1371/journal.pone.0024340.
9. von Eiff C, Becker K, Machka K, Stammer H, Peters G. 2001. Nasal carriage as a source of Staphylococcus aureus bacteremia. N. Engl. J. Med. 344:6-11.
10. Donker JM, van der Laan L, Hendriks YJ, Kluytmans JA. 2012. Evaluation of Staphylococcus aureus nasal carriage screening before vascular surgery. PLoS One 7:e38127. http://dx.doi.org/10.1371/journal.pone .0038127.
11. Kallen AJ, Wilson CT, Larson RJ. 2005. Perioperative intranasal mupirocin for the prevention of surgical-site infections: Systematic review of the literature and meta-analysis. Infect. Control Hosp. Epidemiol. 26:916-922. http://dx.doi.org/10.1086/505453.
12. Engelman R, Shahian D, Shemin R, Guy TS, Bratzler D, Edwards F, Jacobs M, Fernando H, Bridges C. 2007. The Society of Thoracic Surgeons practice guidelines series: Antibiotic prophylaxis in cardiac surgery, part II: Antibiotic choice. Ann. Thorac. Surg. 83:1569-1576. http://dx.doi.org/10.1016/j. athoracsur.2006.09.046.
13. Bode LG, Kluytmans JA, Wertheim HF, Bogaers D, Vandenbroucke-Grauls CM, Roosendaal R, Troelstra A, Box AT, Voss A, van der Tweel I, van Belkum A, Verbrugh HA, Vos MC. 2010. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N. Engl. J. Med. 362:9-17. http://dx.doi.org/10.1056/ NEJMoa0808939.
14. Kalmeijer MD, Coertjens H, van Nieuwland-Bollen PM, Bogaers-Hofman D, de Baere GA, Stuurman A, van Belkum A, Kluytsmans JA. 2002. Surgical site infections in orthopedic surgery: The effect of mupirocin nasal ointment in a doubleblind, randomized, placebo-controlled study. Clin. Infect. Dis. 35:353-358. http://dx.doi.org/10.1086/341025.
15. Weber SG, Huang SS, Oriola S, Huskins WC, Noskin GA, Harriman K, Olmsted RN, Bonten M, Lundstrom T, Climo MW, Roghmann MC, Murphy CL, Karchmer TB. 2007. Legislative mandates for use of active surveillance cultures to screen for methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci: Position statement from the Joint SHEA and APIC Task Force. Infect. Control Hosp. Epidemiol. 28:249-260. http://dx.doi.org/10.1086/512261.
16. White A. 1963. Increased infection rates in heavy nasal carriers of coagulase-positive staphylococci. Antimicrob. Agents Chemother. 161:667-670.
17. Kalmeijer MD, van Nieuwland-Bollen E, Bogaers-Hofman D, de Baere GA. 2000. Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery. Infect. Control Hosp. Epidemiol. 21:319-323. http://dx.doi.org/10.1086/501763.
18. York MK. 2010. Processing, isolation, detection, and interpretation of aerobic bacteriology cultures, p 3.3.1.9-3.3.2.4. In Garcia LS (ed), Clinical microbiology procedures handbook, 3rd ed, vol 1. American Society for Microbiology, Washington, DC.
19. Musher DM, McKenzie SO. 1977. Infections due to Staphylococcus aureus. Medicine 56:383-409.
20. Lee BK, Crossley K, Gerding DN. 1978. The association between Staphylococcus aureus bacteremia and bacteriuria. Am. J. Med. 65:303-306. http://dx.doi.org/10.1016/0002-9343(78)90824-0.
21. Nolan CM, Beaty HN. 1976. Staphylococcus aureus bacteremia: Current clinical patterns. Am. J. Med. 60:495-501. http://dx.doi.org/10.1016/0002- 9343(76)90715-4.
22. Muder RR, Brennen C, Rihs JD, Wagener MM, Obman A, Stout JE, Yu VL. 2006. Isolation of Staphylococcus aureus from the urinary tract: Association of isolation with symptomatic urinary tract infection and subsequent staphylococcal bacteremia. Clin. Infect. Dis. 42:46-50. http://dx.doi.org/10.1086/498518.
23. McDanel JS, Murphy CR, Diekema DJ, Quan V, Kim DS, Peterson EM, Evans KD, Tan GL, Hayden MK, Huang SS. 2013. Chlorhexidine and mupirocin susceptibilities of methicillin-resistant Staphylococcus aureus from colonized nursing home residents. Antimicrob. Agents Chemother. 57:552-558. http://dx.doi.org/10.1128/ AAC.01623-12.
24. Mermel LA, Cartony JM, Covington P, Maxey G, Morse D. 2011. Methicillin-resistant Staphylococcus aureus colonization at different body sites: A prospective, quantitative analysis. J. Clin. Microbiol. 49:1119-1121. http://dx.doi.org/10.1128/JCM.02601-10.
25. Stone ND, Lewis DR, Lowery HK, Darrow LA, Kroll CM, Gaynes RP, Jernigan JA, McGowan JE, Jr, Tenover FC, Richards CL, Jr. 2008. Importance of bacterial burden among methicillin-resistant Staphylococcus aureus carriers in a long-term care facility. Infect. Control Hosp. Epidemiol. 29:143-148. http://dx.doi.org/10.1086/526437.