-
1
-
-
84877803525
-
Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture
-
Alsharidah M, Lazarus NR, George TE, Agley CC, Velloso CP, Harridge SD. Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture. Aging Cell 12: 333-344, 2013.
-
(2013)
Aging Cell
, vol.12
, pp. 333-344
-
-
Alsharidah, M.1
Lazarus, N.R.2
George, T.E.3
Agley, C.C.4
Velloso, C.P.5
Harridge, S.D.6
-
2
-
-
80755172257
-
Human muscle satellite cells show age-related differential expression of S100B protein and RAGE
-
Beccafico S, Riuzzi F, Puglielli C, Mancinelli R, Fulle S, Sorci G, Donato R. Human muscle satellite cells show age-related differential expression of S100B protein and RAGE. Age (Dordr) 33: 523-541, 2011.
-
(2011)
Age (Dordr)
, vol.33
, pp. 523-541
-
-
Beccafico, S.1
Riuzzi, F.2
Puglielli, C.3
Mancinelli, R.4
Fulle, S.5
Sorci, G.6
Donato, R.7
-
4
-
-
40649124537
-
Replicative aging down-regulates the myogenic regulatory factors in human myoblasts
-
Bigot A, Jacquemin V, Debacq-Chainiaux F, Butler-Browne GS, Toussaint O, Furling D, Mouly V. Replicative aging down-regulates the myogenic regulatory factors in human myoblasts. Biol Cell 100: 189-199, 2008.
-
(2008)
Biol Cell
, vol.100
, pp. 189-199
-
-
Bigot, A.1
Jacquemin, V.2
Debacq-Chainiaux, F.3
Butler-Browne, G.S.4
Toussaint, O.5
Furling, D.6
Mouly, V.7
-
5
-
-
37549039009
-
A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis
-
Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA. A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell 2: 50-59, 2008.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 50-59
-
-
Brack, A.S.1
Conboy, I.M.2
Conboy, M.J.3
Shen, J.4
Rando, T.A.5
-
6
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317: 807-810, 2007.
-
(2007)
Science
, vol.317
, pp. 807-810
-
-
Brack, A.S.1
Conboy, M.J.2
Roy, S.3
Lee, M.4
Kuo, C.J.5
Keller, C.6
Rando, T.A.7
-
7
-
-
0024392416
-
Muscle transplantation between young and old rats: Age of host determines recovery
-
Carlson BM, Faulkner JA. Muscle transplantation between young and old rats: age of host determines recovery. Am J Physiol Cell Physiol 256: C1262-C1266, 1989.
-
(1989)
Am J Physiol Cell Physiol
, vol.256
-
-
Carlson, B.M.1
Faulkner, J.A.2
-
8
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433: 760-764, 2005.
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weissman, I.L.5
Rando, T.A.6
-
9
-
-
80054682555
-
Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype
-
Coppe JP, Rodier F, Patil CK, Freund A, Desprez PY, Campisi J. Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. J Biol Chem 286: 36396-36403, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 36396-36403
-
-
Coppe, J.P.1
Rodier, F.2
Patil, C.K.3
Freund, A.4
Desprez, P.Y.5
Campisi, J.6
-
10
-
-
0033572923
-
Wnt signaling and the activation of myogenesis in mammals
-
Cossu G, Borello U. Wnt signaling and the activation of myogenesis in mammals. EMBO J 18: 6867-6872, 1999.
-
(1999)
EMBO J
, vol.18
, pp. 6867-6872
-
-
Cossu, G.1
Borello, U.2
-
11
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, Peacocket M, Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
Peacocket, M.11
Campisi, J.12
-
12
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95: 2509-2514, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
13
-
-
0034832956
-
Regulation of cellular senescence by p53
-
Itahana K, Dimri G, Campisi J. Regulation of cellular senescence by p53. Eur J Biochem 268: 2784-2791, 2001.
-
(2001)
Eur J Biochem
, vol.268
, pp. 2784-2791
-
-
Itahana, K.1
Dimri, G.2
Campisi, J.3
-
14
-
-
79952115737
-
Cellular senescence controls fibrosis in wound healing
-
Jun JI, Lau LF. Cellular senescence controls fibrosis in wound healing. Aging (Albany, NY) 2: 627-631, 2010.
-
(2010)
Aging (Albany, NY)
, vol.2
, pp. 627-631
-
-
Jun, J.I.1
Lau, L.F.2
-
15
-
-
77954243065
-
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
-
Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol 12: 676-685, 2010.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 676-685
-
-
Jun, J.I.1
Lau, L.F.2
-
16
-
-
82455198983
-
Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
-
Jun JI, Lau LF. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat Rev Drug Discov 10: 945-963, 2011.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 945-963
-
-
Jun, J.I.1
Lau, L.F.2
-
17
-
-
0141958058
-
Sarcopenia and aging
-
Kamel HK. Sarcopenia and aging. Nutr Rev 61: 157-167, 2003.
-
(2003)
Nutr Rev
, vol.61
, pp. 157-167
-
-
Kamel, H.K.1
-
18
-
-
28044432532
-
Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women
-
Kim JS, Kosek DJ, Petrella JK, Cross JM, Bamman MM. Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women. J Appl Physiol 99: 2149-2158, 2005.
-
(2005)
J Appl Physiol
, vol.99
, pp. 2149-2158
-
-
Kim, J.S.1
Kosek, D.J.2
Petrella, J.K.3
Cross, J.M.4
Bamman, M.M.5
-
19
-
-
35348945277
-
A single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle
-
Kivela R, Kyrolainen H, Selanne H, Komi PV, Kainulainen H, Vihko V. A single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle. J Appl Physiol 103: 1395-1401, 2007.
-
(2007)
J Appl Physiol
, vol.103
, pp. 1395-1401
-
-
Kivela, R.1
Kyrolainen, H.2
Selanne, H.3
Komi, P.V.4
Kainulainen, H.5
Vihko, V.6
-
20
-
-
77950838411
-
Phosphorylation of UT-A1 on serine 486 correlates with membrane accumulation and urea transport activity in both rat IMCDs and cultured cells
-
Klein JD, Blount MA, Frohlich O, Denson CE, Tan X, Sim JH, Martin CF, Sands JM. Phosphorylation of UT-A1 on serine 486 correlates with membrane accumulation and urea transport activity in both rat IMCDs and cultured cells. Am J Physiol Renal Physiol 298: F935-F940, 2010.
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Klein, J.D.1
Blount, M.A.2
Frohlich, O.3
Denson, C.E.4
Tan, X.5
Sim, J.H.6
Martin, C.F.7
Sands, J.M.8
-
21
-
-
84900969225
-
Ink4a/Arf expression is a biomarker of aging
-
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Ink4a/Arf expression is a biomarker of aging. J Clin Invest 114: 1299-1307, 2004.
-
(2004)
J Clin Invest
, vol.114
, pp. 1299-1307
-
-
Krishnamurthy, J.1
Torrice, C.2
Ramsey, M.R.3
Kovalev, G.I.4
Al-Regaiey, K.5
Su, L.6
Sharpless, N.E.7
-
22
-
-
84885211241
-
Role of reactive oxygen species-mediated signaling in aging
-
Labunskyy VM, Gladyshev VN. Role of reactive oxygen species-mediated signaling in aging. Antioxid Redox Signal 19: 1362-1372, 2013.
-
(2013)
Antioxid Redox Signal
, vol.19
, pp. 1362-1372
-
-
Labunskyy, V.M.1
Gladyshev, V.N.2
-
23
-
-
80052925829
-
CCN1/CYR61: The very model of a modern matricellular protein
-
Lau LF. CCN1/CYR61: the very model of a modern matricellular protein. Cell Mol Life Sci 68: 3149-3163, 2011.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3149-3163
-
-
Lau, L.F.1
-
24
-
-
2242453283
-
Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells
-
Leu SJ, Lam SC, Lau LF. Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells. J Biol Chem 277: 46248-46255, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 46248-46255
-
-
Leu, S.J.1
Lam, S.C.2
Lau, L.F.3
-
25
-
-
29844447503
-
Winding through the WNT pathway during cellular development and demise
-
Li F, Chong ZZ, Maiese K. Winding through the WNT pathway during cellular development and demise. Histol Histopathol 21: 103-124, 2006.
-
(2006)
Histol Histopathol
, vol.21
, pp. 103-124
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
26
-
-
84859991137
-
Cyr61/CCN1 is regulated by Wnt/beta-catenin signaling and plays an important role in the progression of hepatocellular carcinoma
-
Li ZQ, Ding W, Sun SJ, Li J, Pan J, Zhao C, Wu WR, Si WK. Cyr61/CCN1 is regulated by Wnt/beta-catenin signaling and plays an important role in the progression of hepatocellular carcinoma. PLoS One 7: e35754, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Li, Z.Q.1
Ding, W.2
Sun, S.J.3
Li, J.4
Pan, J.5
Zhao, C.6
Wu, W.R.7
Si, W.K.8
-
27
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, Malide D, Rovira II, Schimel D, Kuo CJ, Gutkind JS, Hwang PM, Finkel T. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 317: 803-806, 2007.
-
(2007)
Science
, vol.317
, pp. 803-806
-
-
Liu, H.1
Fergusson, M.M.2
Castilho, R.M.3
Liu, J.4
Cao, L.5
Chen, J.6
Malide, D.7
Rovira, I.I.8
Schimel, D.9
Kuo, C.J.10
Gutkind, J.S.11
Hwang, P.M.12
Finkel, T.13
-
28
-
-
1042266548
-
Modulation of mammalian life span by the short isoform of p53
-
Maier B, Gluba W, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, Thorner M, Scrable H. Modulation of mammalian life span by the short isoform of p53. Genes Dev 18: 306-319, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 306-319
-
-
Maier, B.1
Gluba, W.2
Bernier, B.3
Turner, T.4
Mohammad, K.5
Guise, T.6
Sutherland, A.7
Thorner, M.8
Scrable, H.9
-
29
-
-
42649140551
-
The Wnt signaling pathway: Aging gracefully as a protectionist?
-
Maiese K, Li F, Chong ZZ, Shang YC. The Wnt signaling pathway: aging gracefully as a protectionist? Pharmacol Ther 118: 58-81, 2008.
-
(2008)
Pharmacol Ther
, vol.118
, pp. 58-81
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
Shang, Y.C.4
-
30
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nunez S, Heard E, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113: 703-716, 2003.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Lin, A.W.4
Hearn, S.A.5
Spector, D.L.6
Hannon, G.J.7
Lowe, S.W.8
-
31
-
-
33846839229
-
A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis
-
O'Connor RS, Mills ST, Jones KA, Ho SN, Pavlath GK. A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis. J Cell Sci 120: 149-159, 2007.
-
(2007)
J Cell Sci
, vol.120
, pp. 149-159
-
-
O'Connor, R.S.1
Mills, S.T.2
Jones, K.A.3
Ho, S.N.4
Pavlath, G.K.5
-
32
-
-
67650710794
-
Molecular basis of the myogenic profile of aged human skeletal muscle satellite cells during differentiation
-
Pietrangelo T, Puglielli C, Mancinelli R, Beccafico S, Fano G, Fulle S. Molecular basis of the myogenic profile of aged human skeletal muscle satellite cells during differentiation. Exp Gerontol 44: 523-531, 2009.
-
(2009)
Exp Gerontol
, vol.44
, pp. 523-531
-
-
Pietrangelo, T.1
Puglielli, C.2
Mancinelli, R.3
Beccafico, S.4
Fano, G.5
Fulle, S.6
-
33
-
-
80054988873
-
CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts
-
Quan T, Qin Z, Robichaud P, Voorhees JJ, Fisher GJ. CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts. J Cell Commun Signal 5: 201-207, 2011.
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 201-207
-
-
Quan, T.1
Qin, Z.2
Robichaud, P.3
Voorhees, J.J.4
Fisher, G.J.5
-
34
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 434: 843-850, 2005.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
35
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F, Campisi J. Four faces of cellular senescence. J Cell Biol 192: 547-556, 2011.
-
(2011)
J Cell Biol
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
36
-
-
80555144123
-
Hormone replacement therapy in the geriatric patient: Current state of the evidence and questions for the future. Estrogen, progesterone, testosterone, and thyroid hormone augmentation in geriatric clinical practice: Part 1
-
Schwartz E, Holtorf K. Hormone replacement therapy in the geriatric patient: current state of the evidence and questions for the future. Estrogen, progesterone, testosterone, and thyroid hormone augmentation in geriatric clinical practice: part 1. Clin Geriatr Med 27: 541-559, 2011.
-
(2011)
Clin Geriatr Med
, vol.27
, pp. 541-559
-
-
Schwartz, E.1
Holtorf, K.2
-
37
-
-
80054986476
-
Reduction of myoblast differentiation following multiple population doublings in mouse C2 C12 cells: A model to investigate ageing?
-
Sharples AP, Al-Shanti N, Lewis MP, Stewart CE. Reduction of myoblast differentiation following multiple population doublings in mouse C2 C12 cells: a model to investigate ageing? J Cell Biochem 112: 3773-3785, 2011.
-
(2011)
J Cell Biochem
, vol.112
, pp. 3773-3785
-
-
Sharples, A.P.1
Al-Shanti, N.2
Lewis, M.P.3
Stewart, C.E.4
-
38
-
-
33645816535
-
CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells
-
Si W, Kang Q, Luu HH, Park JK, Luo Q, Song WX, Jiang W, Luo X, Li X, Yin H, Montag AG, Haydon RC, He TC. CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol 26: 2955-2964, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2955-2964
-
-
Si, W.1
Kang, Q.2
Luu, H.H.3
Park, J.K.4
Luo, Q.5
Song, W.X.6
Jiang, W.7
Luo, X.8
Li, X.9
Yin, H.10
Montag, A.G.11
Haydon, R.C.12
He, T.C.13
-
39
-
-
38749151538
-
Transcriptional activation of CCN1 and CCN2, targets of canonical Wnt signal, by ascorbic acid 2-phosphate in human dermal papilla cells
-
Sung YK, Kwack MH, Kim SR, Kim MK, Kim JC. Transcriptional activation of CCN1 and CCN2, targets of canonical Wnt signal, by ascorbic acid 2-phosphate in human dermal papilla cells. J Dermatol Sci 49: 256-259, 2008.
-
(2008)
J Dermatol Sci
, vol.49
, pp. 256-259
-
-
Sung, Y.K.1
Kwack, M.H.2
Kim, S.R.3
Kim, M.K.4
Kim, J.C.5
-
40
-
-
27744465454
-
The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts
-
Todorovic V, Chen CC, Hay N, Lau LF. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. J Cell Biol 171: 559-568, 2005.
-
(2005)
J Cell Biol
, vol.171
, pp. 559-568
-
-
Todorovic, V.1
Chen, C.C.2
Hay, N.3
Lau, L.F.4
-
41
-
-
0037011958
-
p53 mutant mice that display early ageing-associated phenotypes
-
Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA. p53 mutant mice that display early ageing-associated phenotypes. Nature 415: 45-53, 2002.
-
(2002)
Nature
, vol.415
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Igelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
Park, S.H.11
Thompson, T.12
Karsenty, G.13
Bradley, A.14
Donehower, L.A.15
-
42
-
-
33747619854
-
Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling
-
Wang X, Hu Z, Hu J, Du J, Mitch WE. Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology 147: 4160-4168, 2006.
-
(2006)
Endocrinology
, vol.147
, pp. 4160-4168
-
-
Wang, X.1
Hu, Z.2
Hu, J.3
Du, J.4
Mitch, W.E.5
-
43
-
-
80555148894
-
Decreased miR-29 suppresses myogenesis in CKD
-
Wang XH, Hu Z, Klein JD, Zhang L, Fang F, Mitch WE. Decreased miR-29 suppresses myogenesis in CKD. J Am Soc Nephrol 22: 2068-2076, 2011.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 2068-2076
-
-
Wang, X.H.1
Hu, Z.2
Klein, J.D.3
Zhang, L.4
Fang, F.5
Mitch, W.E.6
-
44
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C, Lowe SW. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445: 656-660, 2007.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
45
-
-
77949879161
-
Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy
-
Zhang L, Wang XH, Wang H, Du J, Mitch WE. Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. J Am Soc Nephrol 21: 419-427, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 419-427
-
-
Zhang, L.1
Wang, X.H.2
Wang, H.3
Du, J.4
Mitch, W.E.5
|