Imidazole-derived agonists for the neurotensin 1 receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 1, 2014, Pages 262-267

  Hershberger, Paul M ^a   Hedrick, Michael P ^a   Peddibhotla, Satyamaheshwar ^a   Mangravita Novo, Arianna ^a   Gosalia, Palak ^a   Li, Yujie ^a   Gray, Wilson ^a   Vicchiarelli, Michael ^a   Smith, Layton H ^a   Chung, Thomas D Y ^a   Thomas, James B ^c   Caron, Marc G ^b   Pinkerton, Anthony B ^a   Barak, Lawrence S ^b   Roth, Gregory P ^a  

^a BURNHAM INSTITUTE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c RTI INTERNATIONAL   (United States)

Author keywords

Agonist; Imidazole; Methamphetamine; Neurotensin 1

Indexed keywords

4 AMINOQUINOLINE; IMIDAZOLE DERIVATIVE; NAPHTHALENE DERIVATIVE; NEUROTENSIN 1 RECEPTOR; NEUROTENSIN 2 RECEPTOR; NEUROTENSIN RECEPTOR; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG; ML 301; NAPHTHALENE;

ARTICLE; ARYLATION; BLOOD BRAIN BARRIER; CALCIUM MOBILIZATION ASSAY; CHEMICAL STRUCTURE; DRUG SYNTHESIS; METHAMPHETAMINE DEPENDENCE; MOLECULAR PROBE; PLASMA PROTEIN BINDING; STEREOCHEMISTRY; DRUG IDENTIFICATION; EC50; ELECTRON; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULE; STRUCTURE ACTIVITY RELATION;

AGONIST; IMIDAZOLE; METHAMPHETAMINE; NEUROTENSIN 1;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMIDAZOLES; MICE; MOLECULAR STRUCTURE; RECEPTORS, NEUROTENSIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84891484747     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.11.026     Document Type: Article

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