The alveolar microenvironment of patients infected with human immunodeficiency virus does not modify alveolar macrophage interactions with Streptococcus pneumoniae

Clinical and Vaccine Immunology

Volumn 20, Issue 6, 2013, Pages 907-911

  Gordon, Stephen B ^a,c   Jagoe, R Thomas ^b   Jarman, Elizabeth R ^c   North, James C ^a   Pridmore, Alison ^d   Musaya, Janelisa ^c   French, Neil ^c,e,f   Zijlstra, Eduard E ^g   Molyneux, Malcolm E ^a,c   Read, Robert C ^d,h  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e KARONGA PREVENTION STUDY   (Malawi)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^g UNIVERSITY OF MALAWI   (Malawi)

^h UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTEGRIN; CXCL3 CHEMOKINE; DECTIN 1; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FERRITIN; GAMMA INTERFERON; GELATINASE B; HEME OXYGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 16; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE ELASTASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANGANESE SUPEROXIDE DISMUTASE; PROSTAGLANDIN E2; PROTEIN MD 2; PROTEOGLYCAN; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSCRIPTION FACTOR JUNB; TRANSFORMING GROWTH FACTOR BETA; UROKINASE RECEPTOR;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LUNG ALVEOLUS MACROPHAGE; LUNG ALVEOLUS WALL; LUNG LAVAGE; MALE; MICROARRAY ANALYSIS; MICROENVIRONMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; STREPTOCOCCUS PNEUMONIAE; UPREGULATION; VIRUS LOAD; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; EPITHELIUM CELL; GENE EXPRESSION PROFILING; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; PHAGOCYTOSIS; YOUNG ADULT;

ADULT; BRONCHOALVEOLAR LAVAGE FLUID; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HIV INFECTIONS; HUMANS; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MALE; MICROARRAY ANALYSIS; PHAGOCYTOSIS; REAL-TIME POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE; YOUNG ADULT;

EID: 84891449758     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00582-12     Document Type: Article

References (46)

1. Klugman KP, Madhi SA, Feldman C. 2007. HIV and pneumococcal disease. Curr. Opin. Infect. Dis. 20:11-15. (Pubitemid 46052121)
2. Gill CJ, Mwanakasale V, Fox MP, Chilengi R, Tembo M, Nsofwa M, Chalwe V, Mwananyanda L, Mukwamataba D, Malilwe B, Champo D, Macleod WB, Thea DM, Hamer DH. 2008. Impact of human immunodeficiency virus infection on Streptococcus pneumoniae colonization and seroepidemiology among Zambian women. J. Infect. Dis. 197:1000-1005. (Pubitemid 351590028)
3. Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, Scheinberg P, Price DA, Hage CA, Kohli LM, Khoruts A, Frank I, Else J, Schacker T, Silvestri G, Douek DC. 2008. Differential Th17 CD4 T cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112:2826-2835.
4. Eagan R, Twigg HL, III, French N, Musaya J, Day RB, Zijlstra EE, Tolmie H, Wyler D, Molyneux ME, Gordon SB. 2007. Lung fluid immunoglobulin from HIV-infected subjects has impaired opsonic function against pneumococci. Clin. Infect. Dis. 44:1632-1638. (Pubitemid 46871512)
5. Gordon SB, Molyneux ME, Boeree MJ, Kanyanda S, Chaponda M, Squire SB, Read RC. 2001. Opsonic phagocytosis of Streptococcus pneumoniae by alveolar macrophages is not impaired in human immunodeficiency virus-infected Malawian adults. J. Infect. Dis. 184:1345-1349. (Pubitemid 33055584)
6. Gordon SB, Jarman ER, Kanyanda S, French N, Pridmore AC, Zijlstra EE, Molyneux ME, Read RC. 2005. Reduced interleukin-8 response to Streptococcus pneumoniae by alveolar macrophages from adults with HIV/AIDS. AIDS 19:1197-1200. (Pubitemid 41059261)
7. Holt PG, Strickland DH, Wikstrom ME, Jahnsen FL. 2008. Regulation of immunological homeostasis in the respiratory tract. Nat. Rev. Immunol. 8:142-152. (Pubitemid 351161302)
8. Gordon SB, Read RC. 2002. Macrophage defences against respiratory tract infections. Br. Med. Bull. 61:45-61. (Pubitemid 34477555)
9. Gordon S, Taylor PR. 2005. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5:953-964. (Pubitemid 41746764)
10. Marriott HM, Dockrell DH. 2007. The role of the macrophage in lung disease mediated by bacteria. Exp. Lung Res. 33:493-505. (Pubitemid 350256094)
11. Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit LA, Byers DE, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, Polineni D, Patterson GA, Schwendener RA, Allard JD, Peltz G, Holtzman MJ. 2008. Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat. Med. 14:633-640. (Pubitemid 351809546)
12. Malley R, Henneke P, Morse SC, Cieslewicz MJ, Lipsitch M, Thompson CM, Kurt-Jones E, Paton JC, Wessels MR, Golenbock DT. 2003. Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc. Natl. Acad. Sci. U. S. A. 100:1966-1971. (Pubitemid 36254557)
13. Taylor PR, Martinez-Pomares L, Stacey M, Lin HH, Brown GD, Gordon S. 2005. Macrophage receptors and immune recognition. Annu. Rev. Immunol. 23:901-944. (Pubitemid 40563189)
14. Kadioglu A, Coward W, Colston MJ, Hewitt CRA, Andrew PW. 2004. CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection. Infect. Immun. 72:2689-2697. (Pubitemid 38542395)
15. Marriott HM, Hellewell PG, Cross SS, Ince PG, Whyte MK, Dockrell DH. 2006. Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia. J. Immunol. 177:6480-6488. (Pubitemid 44628867)
16. Gordon S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23-35. (Pubitemid 37328697)
17. + regulatory T cells induce alternative activation of human monocytes/macrophages. Proc. Natl. Acad. Sci. U. S. A. 104:19446-19451.
18. Lewin SR, Sonza S, Irving LB, McDonald CF, Mills J, Crowe SM. 1996. Surface CD4 is critical to in vitro HIV infection of human alveolar macrophages. AIDS Res. Hum. Retroviruses 12:877-883. (Pubitemid 26230784)
19. Porcheray F, Samah B, Leone C, Nreuddre-Bosquet Gras G. 2006. Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a pro-inflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral production. Virology 349:112-120. (Pubitemid 43732479)
20. Twigg HL, Soliman DM, Day RB, Knox KS, Anderson RJ, Wilkes DS, Schnizlein-Bick CT. 1999. Lymphocytic alveolitis, bronchoalveolar lavage viral load, and outcome in human immunodeficiency virus infection. Am. J. Respir. Crit. Care Med. 159:1439-1444. (Pubitemid 29227851)
21. Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. 2006. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12:1365-1371. (Pubitemid 44924494)
22. Chougnet CA, Shearer GM. 2007. Regulatory T cells (Treg) and HIV/AIDS: summary of the September 7-8, 2006 workshop. AIDS Res. Hum. Retroviruses 23:945-952.
23. Lynn DJ, Winsor GL, Chan C, Richard N, Laird MR, Barsky A, Gardy JL, Roche FM, Chan TH, Shah N, Lo R, Naseer M, Que J, Yau M, Acab M, Tulpan D, Whiteside MD, Chikatamarla A, Mah B, Munzner T, Hokamp K, Hancock RE, Brinkman FS. 2008. InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Mol. Syst. Biol. 4:218.
24. Gordon SB, Irving GR, Lawson RA, Lee ME, Read RC. 2000. Intracellular trafficking and killing of Streptococcus pneumoniae by human alveolar macrophages are influenced by opsonins. Infect. Immun. 68:2286- 2293.
25. Tusher VG, Tibshirani R, Chu G. 2001. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. U. S. A. 98:5116-5121. (Pubitemid 32397092)
26. Theocharidis A, van Dongen S, Enright AJ, Freeman TC. 2009. Network visualisation and analysis of gene expression data using BioLayout Express3D. Nat. Protoc. 4:1535-1550.
27. Reference deleted.
28. Hirschtick RE, Glassroth J, Jordan MC, Wilcosky TC, Wallace JM, Kvale PA, Markowitz N, Rosen MJ, Mangura BT, Hopewell PC. 1995. Bacterial pneumonia in persons infected with the human immunodeficiency virus. Pulmonary complications of HIV infection study group. N. Engl. J. Med. 333:845-851.
29. Sierra MJ, Toossi Z, Hom DL, Finegan CK, Hoenig E, Rich EA. 1994. Relationship between load of virus in alveolar macrophages from human immunodeficiency virus type 1-infected persons, production of cytokines, and clinical status. J. Infect. Dis. 169:18-27.
30. Noursadeghi M, Katz DR, Miller RF. 2006. HIV-1 infection of mononuclear phagocytic cells: the case for bacterial innate immune deficiency in AIDS. Lancet Infect. Dis. 6:794-804. (Pubitemid 44894330)
31. Koziel H, Li X, Armstrong MY, Richards FF, Rose RM. 2000. Alveolar macrophages from human immunodeficiency virus-infected persons demonstrate impaired oxidative burst response to Pneumocystis carinii in vitro. Am. J. Respir. Cell Mol. Biol. 23:452-459.
32. Pugliese A, Vidotto V, Beltramo T, Torre D. 2005. Phagocytic activity in human immunodeficiency virus type 1 infection. Clin. Diagn. Lab. Immunol. 12:889-895.
33. Twigg HL, III. 2004. Macrophages in innate and acquired immunity. Semin. Respir. Crit. Care Med. 25:21-31.
34. Giri MS, Nebozhyn M, Showe L, Montaner LJ. 2006. Microarray data on gene modulation by HIV-1 in immune cells: 2000-2006. J. Leukoc. Biol. 80:1031-1043. (Pubitemid 44646309)
35. Twigg HL, Spain BA, III, Soliman DM, Knox K, Sidner RA, Schnizlein-Bick C, Wilkes DS, Iwamoto GK. 1999. Production of interferon-gamma by lung lymphocytes in HIV-infected individuals. Am. J. Physiol. 276:L256-L262. (Pubitemid 29102266)
36. Downing JF, Pasula R, Wright JR, Twigg HL, Martin WJ. 1995. Surfactant protein A promotes attachment of Mycobacterium tuberculosis to alveolar macrophages during infection with human immunodeficiency virus. Proc. Natl. Acad. Sci. U. S. A. 92:4848-4852.
37. Tachado SD, Zhang J, Zhu J, Patel N, Koziel H. 2005. HIV impairs TNF-alpha release in response to Toll-like receptor 4 stimulation in human macrophages in vitro. Am. J. Respir. Cell Mol. Biol. 33:610-621. (Pubitemid 41753137)
38. Didierlaurent A, Goulding J, Patel S, Snelgrove R, Low L, Bebien M, Lawrence T, van Rijt LS, Lambrecht BN, Sirard JC, Hussell T. 2008. Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection. J. Exp. Med. 205:323-329. (Pubitemid 351281598)
39. Elder A, Johnston C, Gelein R, Finkelstein J, Wang Z, Notter R, Oberdorster G. 2005. Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate. Exp. Lung Res. 31:527-546. (Pubitemid 40967240)
40. Fong CH, Bebien M, Didierlaurent A, Nebauer R, Hussell T, Broide D, Karin M, Lawrence T. 2008. An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation. J. Exp. Med. 205:1269-1276. (Pubitemid 351831484)
41. Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. 2005. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 434:1138-1143. (Pubitemid 40663493)
42. Dockrell DH, Marriott HM, Prince LR, Ridger VC, Ince PG, Hellewell PG, Whyte MK. 2003. Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection. J. Immunol. 171:5380-5388. (Pubitemid 37432824)
43. Hoffmann E, Dittrich-Breiholz O, Holtmann H, Kracht M. 2002. Multiple control of interleukin-8 gene expression. J. Leukoc. Biol. 72:847-855. (Pubitemid 35365158)
44. Gordon SB, Kayhty H, Molyneux ME, Haikala R, Nurkka A, Musaya J, Zijlstra EE, Lindell D, French N. 2007. Pneumococcal conjugate vaccine is immunogenic in lung fluid of HIV-infected and immunocompetent adults. J. Allergy Clin. Immunol. 120:208-210. (Pubitemid 46990497)
45. Theron G, Peter J, Lenders L, van Zyl-Smit R, Meldau R, Govender U, Dheda K. 2012. Correlation of mycobacterium tuberculosis specific and nonspecific quantitative Th1 T-cell responses with bacillary load in a high burden setting. PLoS One 7(5):e37436. doi:10.1371/journal.pone.0037436.
46. Brenchley JM, Price DA, Douek DC. 2006. HIV disease: fallout from a mucosal catastrophe? Nat. Immunol. 7:235-239.