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Volumn 3, Issue 1, 2013, Pages 1-6

Does PRRT with standard activities of 177Luoctreotate really achieve relevant somatostatin receptor saturation in target tumor lesions?: Insights from intra-therapeutic receptor imaging in patients with metastatic gastroenteropancreatic neuroendocrine tumors

Author keywords

[No Author keywords available]

Indexed keywords

GALLIUM 68; OCTREOTATE LU 177; RADIOPHARMACEUTICAL AGENT; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 84891440987     PISSN: None     EISSN: 2191219X     Source Type: Journal    
DOI: 10.1186/2191-219X-3-82     Document Type: Article
Times cited : (26)

References (34)
  • 2
    • 0034033495 scopus 로고    scopus 로고
    • Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use
    • Reubi JC, Schar JC, Waser B, Wenger S, Heppeler A, Schmitt JS, Mäcke HR: Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use. Eur J Nucl Med 2000, 27(3):273-282.
    • (2000) Eur J Nucl Med , vol.27 , Issue.3 , pp. 273-282
    • Reubi, J.C.1    Schar, J.C.2    Waser, B.3    Wenger, S.4    Heppeler, A.5    Schmitt, J.S.6    Mäcke, H.R.7
  • 3
    • 0042854927 scopus 로고    scopus 로고
    • Peptide receptors as molecular targets for cancer diagnosis and therapy
    • Reubi JC: Peptide receptors as molecular targets for cancer diagnosis and therapy. Endocr Rev 2003, 24(4):389-427.
    • (2003) Endocr Rev , vol.24 , Issue.4 , pp. 389-427
    • Reubi, J.C.1
  • 5
    • 0037569707 scopus 로고    scopus 로고
    • Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe(1)-Tyr(3)-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors
    • doi:S1536163203000386
    • Kowalski J, Henze M, Schuhmacher J, Macke HR, Hofmann M, Haberkorn U: Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe(1)-Tyr(3)-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors. Mol Imaging Biol 2003, 5(1):42-48. doi:S1536163203000386.
    • (2003) Mol Imaging Biol , vol.5 , Issue.1 , pp. 42-48
    • Kowalski, J.1    Henze, M.2    Schuhmacher, J.3    Macke, H.R.4    Hofmann, M.5    Haberkorn, U.6
  • 7
    • 84861447519 scopus 로고    scopus 로고
    • Does the pretherapeutic tumor SUV in 68Ga DOTATOC PET predict the absorbed dose of 177Lu octreotate?
    • doi:10.1097/RLU.0b013e31823926e5 00003072-201206000-00030
    • Ezziddin S, Lohmar J, Yong-Hing CJ, Sabet A, Ahmadzadehfar H, Kukuk G, Biersack HJ, Guhlke S, Reichmann K: Does the pretherapeutic tumor SUV in 68Ga DOTATOC PET predict the absorbed dose of 177Lu octreotate? Clin Nucl Med 2012, 37(6):e141-e147. doi:10.1097/RLU.0b013e31823926e5 00003072-201206000-00030.
    • (2012) Clin Nucl Med , vol.37 , Issue.6
    • Ezziddin, S.1    Lohmar, J.2    Yong-Hing, C.J.3    Sabet, A.4    Ahmadzadehfar, H.5    Kukuk, G.6    Biersack, H.J.7    Guhlke, S.8    Reichmann, K.9
  • 8
    • 79959208861 scopus 로고    scopus 로고
    • Response, survival, and long-term toxicity after therapy with the radiolabeled somatostatin analogue [90Y-DOTA]-TOC in metastasized neuroendocrine cancers
    • doi:JCO.2010.33.7873 10.1200/JCO.2010.33.7873
    • Imhof A, Brunner P, Marincek N, Briel M, Schindler C, Rasch H, Mäcke HR, Rochlitz C, Müller-Brand J, Walter MA: Response, survival, and long-term toxicity after therapy with the radiolabeled somatostatin analogue [90Y-DOTA]-TOC in metastasized neuroendocrine cancers. J Clin Oncol 2011, 29(17):2416-2423. doi:JCO.2010.33.7873 10.1200/JCO.2010.33.7873.
    • (2011) J Clin Oncol , vol.29 , Issue.17 , pp. 2416-2423
    • Imhof, A.1    Brunner, P.2    Marincek, N.3    Briel, M.4    Schindler, C.5    Rasch, H.6    Mäcke, H.R.7    Rochlitz, C.8    Müller-Brand, J.9    Walter, M.A.10
  • 9
    • 74849111472 scopus 로고    scopus 로고
    • Peptide receptor radionuclide therapy in patients with gastroenteropancreatic neuroendocrine tumors
    • doi:S0001-2998(09)00102-0 10.1053/j.semnuclmed.2009.10.004
    • Kwekkeboom DJ, De Herder WW, Van Eijck CH, Kam BL, Van Essen M, Teunissen JJ, Krenning EP: Peptide receptor radionuclide therapy in patients with gastroenteropancreatic neuroendocrine tumors. Semin Nucl Med 2010, 40(2):78-88. doi:S0001-2998(09)00102-0 10.1053/j.semnuclmed.2009.10.004.
    • (2010) Semin Nucl Med , vol.40 , Issue.2 , pp. 78-88
    • Kwekkeboom, D.J.1    De Herder, W.W.2    Van Eijck, C.H.3    Kam, B.L.4    Van Essen, M.5    Teunissen, J.J.6    Krenning, E.P.7
  • 11
    • 80051705007 scopus 로고    scopus 로고
    • Response and long-term control of bone metastases after peptide receptor radionuclide therapy with (177)Lu-octreotate
    • doi:jnumed.111.090373 10.2967/jnumed.111.090373
    • Ezziddin S, Sabet A, Heinemann F, Yong Hing CJ, Ahmadzadehfar H, Guhlke S, Höller T, Willinek W, Boy C, Biersack HJ: Response and long-term control of bone metastases after peptide receptor radionuclide therapy with (177)Lu-octreotate. J NuclMed 2011, 52(8):1197-1203. doi:jnumed.111.090373 10.2967/jnumed.111.090373.
    • (2011) J NuclMed , vol.52 , Issue.8 , pp. 1197-1203
    • Ezziddin, S.1    Sabet, A.2    Heinemann, F.3    Yong, H.C.J.4    Ahmadzadehfar, H.5    Guhlke, S.6    Höller, T.7    Willinek, W.8    Boy, C.9    Biersack, H.J.10
  • 18
    • 59749083610 scopus 로고    scopus 로고
    • Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro
    • doi:jc.2008-1919 10.1210/jc.2008-1919
    • Lesche S, Lehmann D, Nagel F, Schmid HA, Schulz S: Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro. J Clin Endocrinol Metab 2009, 94(2):654-661. doi:jc.2008-1919 10.1210/jc.2008-1919.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.2 , pp. 654-661
    • Lesche, S.1    Lehmann, D.2    Nagel, F.3    Schmid, H.A.4    Schulz, S.5
  • 19
    • 33947271518 scopus 로고    scopus 로고
    • Neuroendocrine tumors. Peptide receptor radionuclide therapy
    • doi:S1521-690X(07)00008-5 10.1016/j.beem.2007.01.007
    • Forrer F, Valkema R, Kwekkeboom DJ, De Jong M, Krenning EP: Neuroendocrine tumors. Peptide receptor radionuclide therapy. Best Pract Res Clin Endocrinol Metab 2007, 21(1):111-129. doi:S1521-690X(07)00008-5 10.1016/j.beem.2007.01.007.
    • (2007) Best Pract Res Clin Endocrinol Metab , vol.21 , Issue.1 , pp. 111-129
    • Forrer, F.1    Valkema, R.2    Kwekkeboom, D.J.3    De Jong, M.4    Krenning, E.P.5
  • 20
    • 69749089515 scopus 로고    scopus 로고
    • ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Peptide receptor radionuclide therapy with radiolabeled somatostatin analogs
    • Mallorca Consensus Conference participants; European Neuroendocrine Tumor Society
    • Kwekkeboom DJ, Krenning EP, Lebtahi R, Komminoth P, Kos Kudla B, de Herder WW, Plöckinger U, Mallorca Consensus Conference participants; European Neuroendocrine Tumor Society: ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: peptide receptor radionuclide therapy with radiolabeled somatostatin analogs. Neuroendocrinology 2009, 90(2):220-226. doi:000225951 10.1159/000225951.
    • (2009) Neuroendocrinology , vol.90 , Issue.2 , pp. 220-226
    • Kwekkeboom, D.J.1    Krenning, E.P.2    Lebtahi, R.3    Komminoth, P.4    Kos, K.B.5    de Herder, W.W.6    Plöckinger, U.7
  • 22
    • 0037700078 scopus 로고    scopus 로고
    • Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities
    • doi:10.1007/s00259-003-1142-0
    • Breeman WA, De Jong M, Visser TJ, Erion JL, Krenning EP: Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities. Eur J Nucl Med Mol Imaging 2003, 30(6):917-920. doi:10.1007/s00259-003-1142-0.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , Issue.6 , pp. 917-920
    • Breeman, W.A.1    De Jong, M.2    Visser, T.J.3    Erion, J.L.4    Krenning, E.P.5
  • 26
    • 66649130802 scopus 로고    scopus 로고
    • Highly efficient in vivo agonist-induced internalization of sst2 receptors in somatostatin target tissues
    • doi:jnumed.108.061457 10.2967/jnumed.108.061457
    • Waser B, Tamma ML, Cescato R, Maecke HR, Reubi JC: Highly efficient in vivo agonist-induced internalization of sst2 receptors in somatostatin target tissues. J Nucl Med 2009, 50(6):936-941. doi:jnumed.108.061457 10.2967/jnumed.108.061457.
    • (2009) J Nucl Med , vol.50 , Issue.6 , pp. 936-941
    • Waser, B.1    Tamma, M.L.2    Cescato, R.3    Maecke, H.R.4    Reubi, J.C.5
  • 27
    • 21244490346 scopus 로고    scopus 로고
    • 68Ga-DOTANOC: A first compound for PET imaging with high affinity for somatostatin receptor subtypes 2 and 5
    • doi:10.1007/s00259-004-1697-4
    • Wild D, Macke HR, Waser B, Reubi JC, Ginj M, Rasch H, Müller-Brand J, Hofmann M: 68Ga-DOTANOC: a first compound for PET imaging with high affinity for somatostatin receptor subtypes 2 and 5. Eur J Nucl Med Mol Imaging 2005, 32(6):724. doi:10.1007/s00259-004-1697-4.
    • (2005) Eur J Nucl Med Mol Imaging , vol.32 , Issue.6 , pp. 724
    • Wild, D.1    Macke, H.R.2    Waser, B.3    Reubi, J.C.4    Ginj, M.5    Rasch, H.6    Müller-Brand, J.7    Hofmann, M.8
  • 28
    • 77952756362 scopus 로고    scopus 로고
    • Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients
    • doi:jc.2009-2487 10.1210/jc.2009-2487
    • Reubi JC, Waser B, Cescato R, Gloor B, Stettler C, Christ E: Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. J Clin Endocrinol Metab 2010, 95(5):2343-2350. doi:jc.2009-2487 10.1210/jc.2009-2487.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.5 , pp. 2343-2350
    • Reubi, J.C.1    Waser, B.2    Cescato, R.3    Gloor, B.4    Stettler, C.5    Christ, E.6
  • 29
    • 34249792384 scopus 로고    scopus 로고
    • Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2
    • doi:en.2006-1266 10.1210/en.2006-1266
    • Sharif N, Gendron L, Wowchuk J, Sarret P, Mazella J, Beaudet A, Stroh T: Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2. Endocrinology 2007, 148(5):2095-2105. doi:en.2006-1266 10.1210/en.2006-1266.
    • (2007) Endocrinology , vol.148 , Issue.5 , pp. 2095-2105
    • Sharif, N.1    Gendron, L.2    Wowchuk, J.3    Sarret, P.4    Mazella, J.5    Beaudet, A.6    Stroh, T.7
  • 30
    • 80455127123 scopus 로고    scopus 로고
    • Treatment with octreotide does not reduce tumor uptake of (68)Ga-DOTATATE as measured by PET/CT in patients with neuroendocrine tumors
    • doi:jnumed.111.089276 10.2967/jnumed.111.089276
    • Haug AR, Rominger A, Mustafa M, Auernhammer C, Goke B, Schmidt GP, Wängler B, Cumming P, Bartenstein P, Hacker M: Treatment with octreotide does not reduce tumor uptake of (68)Ga-DOTATATE as measured by PET/CT in patients with neuroendocrine tumors. J Nucl Med 2011, 52(11):1679-1683. doi:jnumed.111.089276 10.2967/jnumed.111.089276.
    • (2011) J Nucl Med , vol.52 , Issue.11 , pp. 1679-1683
    • Haug, A.R.1    Rominger, A.2    Mustafa, M.3    Auernhammer, C.4    Goke, B.5    Schmidt, G.P.6    Wängler, B.7    Cumming, P.8    Bartenstein, P.9    Hacker, M.10
  • 31
    • 77950297123 scopus 로고    scopus 로고
    • In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours-impact of peptide mass
    • doi:S0969-8051(09)00288-1 10.1016/j.nucmedbio.2009.11.008
    • Velikyan I, Sundin A, Eriksson B, Lundqvist H, Sorensen J, Bergström M, Långström B: In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours-impact of peptide mass. Nucl Med Biol 2010, 37(3):265-275. doi:S0969-8051(09)00288-1 10.1016/j.nucmedbio.2009.11.008.
    • (2010) Nucl Med Biol , vol.37 , Issue.3 , pp. 265-275
    • Velikyan, I.1    Sundin, A.2    Eriksson, B.3    Lundqvist, H.4    Sorensen, J.5    Bergström, M.6    Långström, B.7
  • 32
    • 0027272429 scopus 로고
    • Improved visualization of carcinoid liver metastases by indium-111 pentetreotide scintigraphy following treatment with cold somatostatin analogue
    • Dorr U, Rath U, Sautter-Bihl ML, Guzman G, Bach D, Adrian HJ, Bihl H: Improved visualization of carcinoid liver metastases by indium-111 pentetreotide scintigraphy following treatment with cold somatostatin analogue. Eur J Nucl Med 1993, 20(5):431-433.
    • (1993) Eur J Nucl Med , vol.20 , Issue.5 , pp. 431-433
    • Dorr, U.1    Rath, U.2    Sautter-Bihl, M.L.3    Guzman, G.4    Bach, D.5    Adrian, H.J.6    Bihl, H.7
  • 33


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.