메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Circulating CD4+CD161+ T lymphocytes are increased in seropositive arthralgia patients but decreased in patients with newly diagnosed rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CD161 ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; METHOTREXATE;

EID: 84891381430     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079370     Document Type: Article
Times cited : (30)

References (37)
  • 1
    • 79955856735 scopus 로고    scopus 로고
    • The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study
    • doi:10.1136/ard.2010.141234. PubMed: 21415052
    • Klarenbeek NB, Güler-Yüksel M, van der Kooij SM, Han KH, Ronday HK et al. (2011) The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study. Ann Rheum Dis 70: 1039-1046. doi:10.1136/ard.2010.141234. PubMed: 21415052.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1039-1046
    • Klarenbeek, N.B.1    Güler-Yüksel, M.2    Van Der Kooij, S.M.3    Han, K.H.4    Ronday, H.K.5
  • 2
    • 77949454420 scopus 로고    scopus 로고
    • Arthritis development in patients with arthralgia is strongly associated with anti-citrullinated protein antibody status: A prospective cohort study
    • doi:10.1136/ard.2008.105759. PubMed: 19363023
    • Bos WH, Wolbink GJ, Boers M, Tijhuis GJ, de Vries N et al. (2010) Arthritis development in patients with arthralgia is strongly associated with anti-citrullinated protein antibody status: A prospective cohort study. Ann Rheum Dis 69: 490-494. doi:10.1136/ard.2008.105759. PubMed: 19363023.
    • (2010) Ann Rheum Dis , vol.69 , pp. 490-494
    • Bos, W.H.1    Wolbink, G.J.2    Boers, M.3    Tijhuis, G.J.4    De Vries, N.5
  • 4
    • 84867081740 scopus 로고    scopus 로고
    • Pre-rheumatoid arthritis: Predisposition and transition to clinical synovitis
    • doi:10.1038/nrrheum.2012.134. PubMed: 22907289
    • Arend WP, Firestein GS (2012) Pre-rheumatoid arthritis: Predisposition and transition to clinical synovitis. Nat Rev Rheumatol 8: 573-586. doi:10.1038/nrrheum.2012.134. PubMed: 22907289.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 573-586
    • Arend, W.P.1    Firestein, G.S.2
  • 5
    • 84862695017 scopus 로고    scopus 로고
    • Th17 cells: Biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies
    • doi:10.1016/j.ajpath.2012.03.044. PubMed: 22640807
    • Maddur MS, Miossec P, Kaveri SV, Bayry J (2012) Th17 cells: Biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies. Am J Pathol 181: 8-18. doi:10.1016/j.ajpath.2012.03.044. PubMed: 22640807.
    • (2012) Am J Pathol , vol.181 , pp. 8-18
    • Maddur, M.S.1    Miossec, P.2    Kaveri, S.V.3    Bayry, J.4
  • 6
    • 77958006636 scopus 로고    scopus 로고
    • Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis
    • doi:10.1186/ar3168. PubMed: 20961415
    • Cascão R, Moura RA, Perpétuo I, Canhão H, Vieira-Sousa E et al. (2010) Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis. Arthritis Res Ther 12: R196. doi:10.1186/ar3168. PubMed: 20961415.
    • (2010) Arthritis Res Ther , vol.12
    • Cascão, R.1    Moura, R.A.2    Perpétuo, I.3    Canhão, H.4    Vieira-Sousa, E.5
  • 7
    • 75749152060 scopus 로고    scopus 로고
    • Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis
    • PubMed: 20112361
    • Kokkonen H, Söderström I, Rocklöv J, Hallmans G, Lejon K et al. (2010) Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis. Arthritis Rheum 62: 383-391. PubMed: 20112361.
    • (2010) Arthritis Rheum , vol.62 , pp. 383-391
    • Kokkonen, H.1    Söderström, I.2    Rocklöv, J.3    Hallmans, G.4    Lejon, K.5
  • 8
    • 50249164315 scopus 로고    scopus 로고
    • Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis
    • PubMed: 18063670
    • Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI et al. (2008) Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis. Ann Rheum Dis 67: 1299-1304. PubMed: 18063670.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1299-1304
    • Yamada, H.1    Nakashima, Y.2    Okazaki, K.3    Mawatari, T.4    Fukushi, J.I.5
  • 9
    • 77957377044 scopus 로고    scopus 로고
    • Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression
    • doi:10.1186/ar3152. PubMed: 20929536
    • Church LD, Filer AD, Hidalgo E, Howlett KA, Thomas AM et al. (2010) Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression. Arthritis Res Ther 12: R184. doi:10.1186/ar3152. PubMed: 20929536.
    • (2010) Arthritis Res Ther , vol.12
    • Church, L.D.1    Filer, A.D.2    Hidalgo, E.3    Howlett, K.A.4    Thomas, A.M.5
  • 10
    • 77957032994 scopus 로고    scopus 로고
    • Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment
    • doi:10.1073/pnas.1003852107. PubMed: 20679229
    • Nistala K, Adams S, Cambrook H, Ursu S, Olivito B et al. (2010) Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment. Proc Natl Acad Sci U S A 107: 14751-14756. doi:10.1073/pnas. 1003852107. PubMed: 20679229.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14751-14756
    • Nistala, K.1    Adams, S.2    Cambrook, H.3    Ursu, S.4    Olivito, B.5
  • 11
    • 79961117793 scopus 로고    scopus 로고
    • Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis
    • doi:10.1002/art.30332. PubMed: 21381000
    • Cosmi L, Cimaz R, Maggi L, Santarlasci V, Capone M et al. (2011) Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis. Arthritis Rheum 63: 2504-2515. doi:10.1002/art.30332. PubMed: 21381000.
    • (2011) Arthritis Rheum , vol.63 , pp. 2504-2515
    • Cosmi, L.1    Cimaz, R.2    Maggi, L.3    Santarlasci, V.4    Capone, M.5
  • 12
    • 0027966063 scopus 로고
    • Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes
    • PubMed: 8077657
    • Lanier LL, Chang C, Phillips JH (1994) Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol 153: 2417-2428. PubMed: 8077657.
    • (1994) J Immunol , vol.153 , pp. 2417-2428
    • Lanier, L.L.1    Chang, C.2    Phillips, J.H.3
  • 13
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
    • doi:10.1084/jem.20080397. PubMed: 18663128
    • Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M et al. (2008) Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J Exp Med 205: 1903-1916. doi:10.1084/jem.20080397. PubMed: 18663128.
    • (2008) J Exp Med , vol.205 , pp. 1903-1916
    • Cosmi, L.1    De Palma, R.2    Santarlasci, V.3    Maggi, L.4    Capone, M.5
  • 14
    • 63449133361 scopus 로고    scopus 로고
    • Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
    • doi:10.1084/jem.20081712. PubMed: 19273624
    • Kleinschek MA, Boniface K, Sadekova S, Grein J, Murphy EE et al. (2009) Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. J Exp Med 206: 525-534. doi:10.1084/jem.20081712. PubMed: 19273624.
    • (2009) J Exp Med , vol.206 , pp. 525-534
    • Kleinschek, M.A.1    Boniface, K.2    Sadekova, S.3    Grein, J.4    Murphy, E.E.5
  • 15
    • 84877339564 scopus 로고    scopus 로고
    • Main features of human T helper 17 cells
    • doi:10.1111/nyas.12075. PubMed: 23651196
    • Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S (2013) Main features of human T helper 17 cells. Ann N Y Acad Sci 1284: 66-70. doi:10.1111/nyas.12075. PubMed: 23651196.
    • (2013) Ann N Y Acad Sci , vol.1284 , pp. 66-70
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Maggi, E.4    Romagnani, S.5
  • 16
    • 77956124982 scopus 로고    scopus 로고
    • CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC
    • doi:10.1002/eji.200940257. PubMed: 20486123
    • Maggi L, Santarlasci V, Capone M, Peired A, Frosali F et al. (2010) CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC. Eur J Immunol 40: 2174-2181. doi:10.1002/eji.200940257. PubMed: 20486123.
    • (2010) Eur J Immunol , vol.40 , pp. 2174-2181
    • Maggi, L.1    Santarlasci, V.2    Capone, M.3    Peired, A.4    Frosali, F.5
  • 17
    • 84871312272 scopus 로고    scopus 로고
    • Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells
    • doi:10.1002/eji.201242648. PubMed: 22965818
    • Maggi L, Santarlasci V, Capone M, Rossi MC, Querci V et al. (2012) Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells. Eur J Immunol 42: 3180-3188. doi:10.1002/eji.201242648. PubMed: 22965818.
    • (2012) Eur J Immunol , vol.42 , pp. 3180-3188
    • Maggi, L.1    Santarlasci, V.2    Capone, M.3    Rossi, M.C.4    Querci, V.5
  • 18
    • 84866749073 scopus 로고    scopus 로고
    • Defining the human T helper 17 cell phenotype
    • doi:10.1016/j.it.2012.05.004. PubMed: 22682163
    • Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S (2012) Defining the human T helper 17 cell phenotype. Trends Immunol 33: 505-512. doi:10.1016/j.it.2012.05.004. PubMed: 22682163.
    • (2012) Trends Immunol , vol.33 , pp. 505-512
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Maggi, E.4    Romagnani, S.5
  • 19
    • 0023945481 scopus 로고
    • The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF et al. (1988) The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31: 315-324.
    • (1988) Arthritis Rheum , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3    McShane, D.J.4    Fries, J.F.5
  • 20
    • 77956036473 scopus 로고    scopus 로고
    • 2010 rheumatoid arthritis classification criteria: An american college of Rheumatology/European league against rheumatism collaborative initiative
    • doi:10.1136/ard.2010.138461. PubMed: 20699241
    • Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT et al. (2010) 2010 rheumatoid arthritis classification criteria: An american college of Rheumatology/European league against rheumatism collaborative initiative. Ann Rheum Dis 69: 1580-1588. doi:10.1136/ard.2010.138461. PubMed: 20699241.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1580-1588
    • Aletaha, D.1    Neogi, T.2    Silman, A.J.3    Funovits, J.4    Felson, D.T.5
  • 21
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • doi:10.1146/annurev.immunol.22.012703.104702. PubMed: 15032595
    • Sallusto F, Geginat J, Lanzavecchia A (2004) Central memory and effector memory T cell subsets: Function, generation, and maintenance. Annu Rev Immunol 22: 745-763. doi:10.1146/annurev.immunol.22.012703.104702. PubMed: 15032595.
    • (2004) Annu Rev Immunol , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 22
    • 45149093251 scopus 로고    scopus 로고
    • Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse
    • doi:10.1136/ard.2007.073833. PubMed: 17644540
    • Burgoyne CH, Field SL, Brown AK, Hensor EM, English A et al. (2008) Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse. Ann Rheum Dis 67: 750-757. doi:10.1136/ard.2007.073833. PubMed: 17644540.
    • (2008) Ann Rheum Dis , vol.67 , pp. 750-757
    • Burgoyne, C.H.1    Field, S.L.2    Brown, A.K.3    Hensor, E.M.4    English, A.5
  • 23
    • 0030870619 scopus 로고    scopus 로고
    • Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. Direct evidence that the NKRP1A molecule is involved in transendothelial migration
    • doi:10.1002/eji.1830270932. PubMed: 9341779
    • Poggi A, Costa P, Zocchi MR, Moretta L (1997) Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. direct evidence that the NKRP1A molecule is involved in transendothelial migration. Eur J Immunol 27: 2345-2350. doi:10.1002/eji.1830270932. PubMed: 9341779.
    • (1997) Eur J Immunol , vol.27 , pp. 2345-2350
    • Poggi, A.1    Costa, P.2    Zocchi, M.R.3    Moretta, L.4
  • 24
    • 4544222573 scopus 로고    scopus 로고
    • Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression
    • doi:10.1002/path.1607. PubMed: 15307135
    • Page G, Miossec P (2004) Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression. J Pathol 204: 28-38. doi:10.1002/path.1607. PubMed: 15307135.
    • (2004) J Pathol , vol.204 , pp. 28-38
    • Page, G.1    Miossec, P.2
  • 25
    • 36549019912 scopus 로고    scopus 로고
    • Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
    • doi:10.1084/jem.20071397. PubMed: 18025126
    • Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S et al. (2007) Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med 204: 2803-2812. doi:10.1084/jem.20071397. PubMed: 18025126.
    • (2007) J Exp Med , vol.204 , pp. 2803-2812
    • Hirota, K.1    Yoshitomi, H.2    Hashimoto, M.3    Maeda, S.4    Teradaira, S.5
  • 26
    • 67650642275 scopus 로고    scopus 로고
    • CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6
    • doi:10.1016/j.cyto.2009.05.009. PubMed: 19535263
    • Tanida S, Yoshitomi H, Nishitani K, Ishikawa M, Kitaori T et al. (2009) CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6. Cytokine 47: 112-118. doi:10.1016/j.cyto.2009.05.009. PubMed: 19535263.
    • (2009) Cytokine , vol.47 , pp. 112-118
    • Tanida, S.1    Yoshitomi, H.2    Nishitani, K.3    Ishikawa, M.4    Kitaori, T.5
  • 27
    • 0026543255 scopus 로고
    • Biannual radiographic assessments of hands and feet in a three-year prospective followup of patients with early rheumatoid arthritis
    • doi:10.1002/art.1780350105. PubMed: 1731813
    • van der Heijde DM, van Leeuwen MA, van Riel PL, Koster AM, van 't Hof MA et al. (1992) Biannual radiographic assessments of hands and feet in a three-year prospective followup of patients with early rheumatoid arthritis. Arthritis Rheum 35: 26-34. doi:10.1002/art.1780350105. PubMed: 1731813.
    • (1992) Arthritis Rheum , vol.35 , pp. 26-34
    • Van Der Heijde, D.M.1    Van Leeuwen, M.A.2    Van Riel, P.L.3    Koster, A.M.4    Van 'T Hof, M.A.5
  • 28
    • 0031874951 scopus 로고    scopus 로고
    • Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis
    • doi:10.1093/rheumatology/37.5.502. PubMed: 9651076
    • Dolhain RJ, Tak PP, Dijkmans BA, De Kuiper P, Breedveld FC et al. (1998) Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis. Br J Rheumatol 37: 502-508. doi:10.1093/rheumatology/37.5.502. PubMed: 9651076.
    • (1998) Br J Rheumatol , vol.37 , pp. 502-508
    • Dolhain, R.J.1    Tak, P.P.2    Dijkmans, B.A.3    De Kuiper, P.4    Breedveld, F.C.5
  • 29
    • 0034800752 scopus 로고    scopus 로고
    • Successful treatment of rheumatoid arthritis is associated with a reduction in synovial membrane cytokines and cell adhesion molecule expression
    • (Oxford) doi:10.1093/rheumatology/40.9.965. PubMed: 11561106
    • Smith MD, Slavotinek J, Au V, Weedon H, Parker A et al. (2001) Successful treatment of rheumatoid arthritis is associated with a reduction in synovial membrane cytokines and cell adhesion molecule expression. Rheumatology (Oxford) 40: 965-977. doi:10.1093/rheumatology/40.9.965. PubMed: 11561106.
    • (2001) Rheumatology , vol.40 , pp. 965-977
    • Smith, M.D.1    Slavotinek, J.2    Au, V.3    Weedon, H.4    Parker, A.5
  • 30
    • 85027912404 scopus 로고    scopus 로고
    • Frequencies of circulating IL-17-producing CD4+CD161+ T cells and CD4+CD161+ T cells correlate with disease activity in rheumatoid arthritis
    • PubMed: 23568758
    • Miao J, Geng J, Zhang K, Li X, Li Q et al. (2013) Frequencies of circulating IL-17-producing CD4+CD161+ T cells and CD4+CD161+ T cells correlate with disease activity in rheumatoid arthritis. Mod Rheumatol. PubMed: 23568758
    • (2013) Mod Rheumatol
    • Miao, J.1    Geng, J.2    Zhang, K.3    Li, X.4    Li, Q.5
  • 31
    • 29144438027 scopus 로고    scopus 로고
    • Cutting edge: Lectin-like transcript 1 is a ligand for the CD161 receptor
    • PubMed: 16339512
    • Aldemir H, Prod'homme V, Dumaurier MJ, Retiere C, Poupon G et al. (2005) Cutting edge: Lectin-like transcript 1 is a ligand for the CD161 receptor. J Immunol 175: 7791-7795. PubMed: 16339512.
    • (2005) J Immunol , vol.175 , pp. 7791-7795
    • Aldemir, H.1    Prod'Homme, V.2    Dumaurier, M.J.3    Retiere, C.4    Poupon, G.5
  • 32
    • 29144444611 scopus 로고    scopus 로고
    • Cutting edge: Lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor
    • PubMed: 16339513
    • Rosen DB, Bettadapura J, Alsharifi M, Mathew PA, Warren HS et al. (2005) Cutting edge: Lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. J Immunol 175: 7796-7799. PubMed: 16339513.
    • (2005) J Immunol , vol.175 , pp. 7796-7799
    • Rosen, D.B.1    Bettadapura, J.2    Alsharifi, M.3    Mathew, P.A.4    Warren, H.S.5
  • 33
    • 78149238230 scopus 로고    scopus 로고
    • Characterization of alternatively spliced transcript variants of CLEC2D gene
    • doi:10.1074/jbc.M110.179622. PubMed: 20843815
    • Germain C, Bihl F, Zahn S, Poupon G, Dumaurier MJ et al. (2010) Characterization of alternatively spliced transcript variants of CLEC2D gene. J Biol Chem 285: 36207-36215. doi:10.1074/jbc.M110.179622. PubMed: 20843815.
    • (2010) J Biol Chem , vol.285 , pp. 36207-36215
    • Germain, C.1    Bihl, F.2    Zahn, S.3    Poupon, G.4    Dumaurier, M.J.5
  • 34
    • 45549100768 scopus 로고    scopus 로고
    • Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells
    • PubMed: 18453569
    • Rosen DB, Cao W, Avery DT, Tangye SG, Liu YJ et al. (2008) Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells. J Immunol 180: 6508-6517. PubMed: 18453569.
    • (2008) J Immunol , vol.180 , pp. 6508-6517
    • Rosen, D.B.1    Cao, W.2    Avery, D.T.3    Tangye, S.G.4    Liu, Y.J.5
  • 35
    • 80055065444 scopus 로고    scopus 로고
    • Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-γ contributes to modulate immune responses
    • doi:10.1074/jbc.M111.285312. PubMed: 21930700
    • Germain C, Meier A, Jensen T, Knapnougel P, Poupon G et al. (2011) Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-γ contributes to modulate immune responses. J Biol Chem 286: 37964-37975. doi:10.1074/jbc.M111.285312. PubMed: 21930700.
    • (2011) J Biol Chem , vol.286 , pp. 37964-37975
    • Germain, C.1    Meier, A.2    Jensen, T.3    Knapnougel, P.4    Poupon, G.5
  • 36
    • 77649146866 scopus 로고    scopus 로고
    • Gene expression profiling in autoantibodypositive patients with arthralgia predicts development of arthritis
    • doi:10.1002/art.27294. PubMed: 20131234
    • van Baarsen LG, Bos WH, Rustenburg F, van der Pouw Kraan TC, Wolbink GJ et al. (2010) Gene expression profiling in autoantibodypositive patients with arthralgia predicts development of arthritis. Arthritis Rheum 62: 694-704. doi:10.1002/art.27294. PubMed: 20131234.
    • (2010) Arthritis Rheum , vol.62 , pp. 694-704
    • Van Baarsen, L.G.1    Bos, W.H.2    Rustenburg, F.3    Van Der Pouw Kraan, T.C.4    Wolbink, G.J.5
  • 37
    • 33748749337 scopus 로고    scopus 로고
    • Synovitis score: Discrimination between chronic low-grade and high-grade synovitis
    • doi:10.1111/j.1365-2559.2006.02508.x. PubMed: 16978198
    • Krenn V, Morawietz L, Burmester GR, Kinne RW, Mueller-Ladner U et al. (2006) Synovitis score: Discrimination between chronic low-grade and high-grade synovitis. Histopathology 49: 358-364. doi:10.1111/j.1365-2559.2006.02508.x. PubMed: 16978198.
    • (2006) Histopathology , vol.49 , pp. 358-364
    • Krenn, V.1    Morawietz, L.2    Burmester, G.R.3    Kinne, R.W.4    Mueller-Ladner, U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.