Intracellular tubulo-reticular structures of peripheral blood mononuclear cells as an ultra-structural marker of disease activity in systemic lupus erythematosus: A pilot study

International Journal of Rheumatic Diseases

Volumn 16, Issue 6, 2013, Pages 692-697

  Mak, Anselm ^a   Almsherqi, Zakaria A M ^b   Lai, Ya Wei ^c   Cheak, Alicia A C ^a   Deng, Yuru ^d  

^a University Medicine Cluster   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHANGZHOU UNIVERSITY   (China)

Author keywords

Cubic membranes; Disease activity; Lupus; Stress; Tubulo reticular

Indexed keywords

ALPHA INTERFERON; PREDNISOLONE;

ADULT; ARTICLE; B LYMPHOCYTE; CELL STRUCTURE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHYSIOLOGICAL STRESS; PILOT STUDY; PRIORITY JOURNAL; SLEDAI; SYSTEMIC LUPUS ERYTHEMATOSUS; TRANSMISSION ELECTRON MICROSCOPY; TUBULO RETICULAR STRUCTURE;

CUBIC MEMBRANES; DISEASE ACTIVITY; LUPUS; STRESS; TUBULO-RETICULAR;

ADULT; B-LYMPHOCYTES; CASE-CONTROL STUDIES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INTERFERON-ALPHA; INTRACELLULAR MEMBRANES; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; ORGANELLES; PILOT PROJECTS; STRESS, PHYSIOLOGICAL; TIME FACTORS;

EID: 84891373463     PISSN: 17561841     EISSN: 1756185X     Source Type: Journal    
DOI: 10.1111/1756-185X.12195     Document Type: Article

References (15)

1. Lozovoy MA, Simão AN, Panis C et al. (2011) Oxidative stress is associated with liver damage, inflammatory status, and corticosteroid therapy in patients with systemic lupus erythematosus. Lupus 20, 1250-9.
2. Shah D, Wanchu A, Bhatnagar A (2011) Interaction between oxidative stress and chemokines: possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis. Immunobiology 216, 1010-7.
3. Wang G, Pierangeli SS, Papalardo E, Ansari GA, Khan MF (2010) Markers of oxidative and nitrosative stress in systemic lupus erythematosus: correlation with disease activity. Arthritis Rheum 62, 2064-72.
4. Alves JD, Grima B (2003) Oxidative stress in systemic lupus erythematosus and antiphospholipid syndrome: a gateway to atherosclerosis. Curr Rheumatol Rep 5, 383-90.
5. Wright SA, O'Prey FM, McHenry MT et al. (2008) A randomised interventional trial of omega-3-polyunsaturated fatty acids on endothelial function and disease activity in systemic lupus erythematosus. Ann Rheum Dis 67, 841-8.
6. Almsherqi ZA, Kohlwein SD, Deng Y (2006) Cubic membranes: a legend beyond the Flatland* of cell membrane organization. J Cell Biol 173, 839-44.
7. Feldman D, Swarm RL, Becker J (1981) Ultrastructural study of rat liver and liver neoplasms after long-term treatment with phenobarbital. Cancer Res 41, 2151-62.
8. Almsherqi ZA, McLachlan CS, Mossop P, Knoops K, Deng Y (2005) Direct template matching reveals a host subcellular membrane gyroid cubic structure that is associated with SARS virus. Redox Rep 10, 167-71.
9. Deng Y, Kohlwein SD, Mannella CA (2002) Fasting induces cyanide-resistant respiration and oxidative stress in the amoeba Chaos carolinensis: implications for the cubic structural transition in mitochondrial membranes. Protoplasma 219, 160-7.
10. Helder AW, Feltkamp-Vroom TM (1976) Tubuloreticular structures and antinuclear antibodies in autoimmune and non-autoimmune diseases. J Pathol 119, 49-56.
11. Venkataseshan VS, Marquet E, Grishman E (1991) Significance of cytoplasmic inclusions in lupus nephritis. Ultrastruct Pathol 15, 1-14.
12. Klippel JH, Carette S, Preble OT, Friedman RM, Grimley PM (1985) Serum alpha interferon and lymphocyte inclusions in systemic lupus erythematosus. Ann Rheum Dis 44, 104-8.
13. Ma CY, Jiao YL, Zhang J et al. (2012) Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-alpha and TNF-alpha in systemic lupus erythematosus. Rheumatol Int 32, 395-402.
14. Hochberg MC (1997) Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40, 1725.
15. Gladman DD, Urowitz MB, Goldsmith CH et al. (1997) The reliability of the systemic lupus international collaborating clinics/American college of rheumatology damage index in patients with systemic lupus erythematosus. Arthritis Rheum 40, 809-1313.