Modulation of chondrocyte functions and stiffness-dependent cartilage repair using an injectable enzymatically crosslinked hydrogelwith tunable mechanical properties

Biomaterials

Volumn 35, Issue 7, 2014, Pages 2207-2217

  Wang, Li Shan ^a   Du, Chan ^a   Toh, Wei Seong ^a,b   Wan, Andrew C A ^a   Gao, Shu Jun ^a   Kurisawa, Motoichi ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Cartilage; Chondrocyte; Hydrogel; Injectable; Stiffness

Indexed keywords

CHONDROCYTES; HORSERADISH PEROXIDASE; INJECTABLE; INJECTABLE HYDROGELS; OSTEOCHONDRAL DEFECTS; OXIDATIVE COUPLINGS; SULFATED GLYCOSAMINOGLYCANS; THREE-DIMENSIONAL (3D) ENVIRONMENTS;

BIOCHEMISTRY; BODY FLUIDS; CARTILAGE; CELL PROLIFERATION; COLLAGEN; GENE EXPRESSION; HYDROGELS; REPAIR; SURFACE DEFECTS; THREE DIMENSIONAL;

STIFFNESS;

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; GELATIN; GLYCOSAMINOGLYCAN; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; HYDROXYPHENYLPROPIONIC ACID; PHENYLPROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BONE DEFECT; CARTILAGE CELL; CATALYSIS; CELL FUNCTION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FLOW KINETICS; GENE EXPRESSION; HISTOPATHOLOGY; HYDROGEL; IMMUNOHISTOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RIGIDITY; TISSUE ENGINEERING; TISSUE REGENERATION; TISSUE REPAIR; YOUNG MODULUS;

ARMORACIA RUSTICANA; ORYCTOLAGUS CUNICULUS;

CARTILAGE; CHONDROCYTE; HYDROGEL; INJECTABLE; STIFFNESS;

ANIMALS; BIOMECHANICAL PHENOMENA; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; HYDROGELS; RABBITS; REAL-TIME POLYMERASE CHAIN REACTION; RHEOLOGY;

EID: 84891372388     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.11.070     Document Type: Article

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