Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells

ACS Nano

Volumn 7, Issue 12, 2013, Pages 11129-11137

  Anselmo, Aaron C ^a   Gupta, Vivek ^a,c   Zern, Blaine J ^b   Pan, Daniel ^b   Zakrewsky, Michael ^a   Muzykantov, Vladimir ^b   Mitragotri, Samir ^a  

^a University of California   (United States)

^b University of Pennsylvania   (United States)

^c KECK GRADUATE INSTITUTE   (United States)

Author keywords

cell mediated drug delivery; hitchhiking; nanomedicine; nanotechnology

Indexed keywords

CLINICAL UTILITY; EXPOSED SURFACES; HITCHHIKING; IN-VIVO; NANOPARTICULATE DRUG DELIVERY SYSTEMS; NEW APPLICATIONS; NONCOVALENT ATTACHMENT; RED BLOOD CELL;

BIOLOGICAL ORGANS; BLOOD; CELLS; DISEASE CONTROL; DRUG DELIVERY; MEDICAL NANOTECHNOLOGY; NANOTECHNOLOGY;

NANOPARTICLES;

INTERCELLULAR ADHESION MOLECULE 1; NANOPARTICLE; POLYSTYRENE DERIVATIVE;

ADSORPTION; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL SEPARATION; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENDOTHELIUM; ERYTHROCYTE; FEMALE; FLOW CYTOMETRY; LIVER; LUNG; LUNG DISEASE; MECHANICAL STRESS; MICROCIRCULATION; MOUSE; NANOTECHNOLOGY; SPLEEN; TISSUE DISTRIBUTION; VASCULARIZATION;

ADSORPTION; ANIMALS; CELL SEPARATION; DRUG DELIVERY SYSTEMS; ENDOTHELIUM; ERYTHROCYTES; FEMALE; FLOW CYTOMETRY; INTERCELLULAR ADHESION MOLECULE-1; LIVER; LUNG; LUNG DISEASES; MICE; MICE, INBRED BALB C; MICROCIRCULATION; NANOPARTICLES; NANOTECHNOLOGY; POLYSTYRENES; SPLEEN; STRESS, MECHANICAL; TISSUE DISTRIBUTION;

EID: 84891358668     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn404853z     Document Type: Article

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