메뉴 건너뛰기




Volumn 10, Issue 1, 2014, Pages 9-15

Cost analysis of initial highly active antiretroviral therapy regimens for managing human immunodeficiency virus-infected patients according to clinical practice in a hospital setting

Author keywords

HAART; HIV; Multi tablet regimen; Pharmacoeconomics; Single tablet regimen

Indexed keywords

ATAZANAVIR PLUS RITONAVIR; DARUNAVIR PLUS RITONAVIR; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; LOPINAVIR PLUS RITONAVIR;

EID: 84891110614     PISSN: 11766336     EISSN: 1178203X     Source Type: Journal    
DOI: 10.2147/TCRM.S49428     Document Type: Article
Times cited : (12)

References (31)
  • 1
    • 0038162585 scopus 로고    scopus 로고
    • Decline in the AIDS and death rates in the EuroSIDA study: An observational study
    • EuroSIDA study group
    • Mocroft A, Ledergerber B, Katlama C, et al; EuroSIDA study group. Decline in the AIDS and death rates in the EuroSIDA study: an observational study. Lancet. 2003;362(9377):22-29.
    • (2003) Lancet , vol.362 , Issue.9377 , pp. 22-29
    • Mocroft, A.1    Ledergerber, B.2    Katlama, C.3
  • 2
    • 47649115323 scopus 로고    scopus 로고
    • Life expectancy of individuals on combination antiretroviral therapy in high-income countries: A collaborative analysis of 14 cohort studies
    • Antiretroviral Therapy Cohort Collaboration, July 26
    • Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet. July 26, 2008;372(9635):293-299.
    • (2008) Lancet , vol.372 , Issue.9635 , pp. 293-299
  • 3
    • 77954734865 scopus 로고    scopus 로고
    • Antiretroviral therapy and management of HIV infection
    • Volberding PA, Deeks SG. Antiretroviral therapy and management of HIV infection. Lancet. 2010;376(9734):49-62.
    • (2010) Lancet , vol.376 , Issue.9734 , pp. 49-62
    • Volberding, P.A.1    Deeks, S.G.2
  • 4
    • 0035869435 scopus 로고    scopus 로고
    • The cost effectiveness of combination antiretroviral therapy for HIV disease
    • Freedberg KA, Losina E, Weinstein MC, et al. The cost effectiveness of combination antiretroviral therapy for HIV disease. N Engl J Med. 2001;344(11):824-831.
    • (2001) N Engl J Med , vol.344 , Issue.11 , pp. 824-831
    • Freedberg, K.A.1    Losina, E.2    Weinstein, M.C.3
  • 5
    • 84891131514 scopus 로고    scopus 로고
    • National Committee on AIDS, Ministry of Health National Commission for the Fight Against AIDS., [Italian guidelines on antiretroviral drugs and the diagnostic-clinical management of HIV patients]. 2012. Italian. Available at, Accessed September 15
    • National Committee on AIDS, Ministry of Health National Commission for the Fight Against AIDS. Linee Guida Italiane sull'utilizzo dei farmaci antiretrovirali e sulla gestione diagnostico-clinica delle persone con infezione da HIV-1 [Italian guidelines on antiretroviral drugs and the diagnostic-clinical management of HIV patients]. 2012. Italian. Available at: http://www.salute.gov.it/imgs/C_17_pubblicazioni_1793_allegato.pdf. Accessed September 15, 2013.
    • (2013) Linee Guida Italiane Sull'utilizzo Dei Farmaci Antiretrovirali E Sulla Gestione Diagnostico-clinica Delle Persone Con Infezione Da HIV-1
  • 6
    • 84866492299 scopus 로고    scopus 로고
    • Twice-daily versus oncedaily antiretroviral therapy and coformulation strategies in HIV infected adults: Benefits, risks, or burden?
    • Nachega JB, Rosenkranz B, Pham PA. Twice-daily versus oncedaily antiretroviral therapy and coformulation strategies in HIV infected adults: benefits, risks, or burden? Patient Prefer Adherence. 2011;5:645-651.
    • (2011) Patient Prefer Adherence , vol.5 , pp. 645-651
    • Nachega, J.B.1    Rosenkranz, B.2    Pham, P.A.3
  • 7
    • 0036749951 scopus 로고    scopus 로고
    • Simpler regimens may enhance adherence to antiretrovirals in HIV-infected patients
    • Maggiolo F, Ripamonti D, Arici C, et al. Simpler regimens may enhance adherence to antiretrovirals in HIV-infected patients. HIV Clin Trials. 2002;3(5):371-378.
    • (2002) HIV Clin Trials , vol.3 , Issue.5 , pp. 371-378
    • Maggiolo, F.1    Ripamonti, D.2    Arici, C.3
  • 8
    • 3042775345 scopus 로고    scopus 로고
    • Perspectives on adherence and simplicity for HIV-infected patients on antiretroviral therapy: Self-report of the relative importance of multiple attributes of highly active antiretroviral therapy (HAART) regimens in predicting adherence
    • Stone VE, Jordan J, Tolson J, Miller R, Pilon T. Perspectives on adherence and simplicity for HIV-infected patients on antiretroviral therapy: self-report of the relative importance of multiple attributes of highly active antiretroviral therapy (HAART) regimens in predicting adherence. J Acquir Immune Defic Syndr. 2004;36(3):808-816.
    • (2004) J Acquir Immune Defic Syndr , vol.36 , Issue.3 , pp. 808-816
    • Stone, V.E.1    Jordan, J.2    Tolson, J.3    Miller, R.4    Pilon, T.5
  • 9
    • 45949108248 scopus 로고    scopus 로고
    • Randomization to once-daily stavudine extended release/lamivudine/efavirenz versus a more frequent regimen improves adherence while maintaining viral suppression
    • Boyle BA, Jayaweera D, Witt MD, Grimm K, Maa JF, Seekins DW. Randomization to once-daily stavudine extended release/lamivudine/efavirenz versus a more frequent regimen improves adherence while maintaining viral suppression. HIV Clin Trials. 2008;9(3):164-176.
    • (2008) HIV Clin Trials , vol.9 , Issue.3 , pp. 164-176
    • Boyle, B.A.1    Jayaweera, D.2    Witt, M.D.3    Grimm, K.4    Maa, J.F.5    Seekins, D.W.6
  • 10
    • 77954618054 scopus 로고    scopus 로고
    • One-pill once-a-day HAART: A simplification strategy that improves adherence and quality of life of HIV-infected subjects
    • Airoldi M, Zaccarelli M, Bisi L, et al. One-pill once-a-day HAART: a simplification strategy that improves adherence and quality of life of HIV-infected subjects. Patient Prefer Adherence. 2010;4: 115-125.
    • (2010) Patient Prefer Adherence , vol.4 , pp. 115-125
    • Airoldi, M.1    Zaccarelli, M.2    Bisi, L.3
  • 11
    • 62949147825 scopus 로고    scopus 로고
    • Atripla [summar y of European public assessment report]. London: EMA; 2009 [updated October 3, 2012]. Available at, Accessed June 10
    • European Medicines Agency (EMA). Atripla [summar y of European public assessment report]. London: EMA; 2009 [updated October 3, 2012]. Available at: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000797/human_med_000657.jsp&murl=menus/medicines/medicines.jsp&mid=WC0b01ac058001d125. Accessed June 10, 2013.
    • (2013) European Medicines Agency (EMA)
  • 12
    • 84891048471 scopus 로고    scopus 로고
    • Lombardy Region, No 937/2010. Milan: Lombardy Region, Italian. Available at, Accessed June 10, 2012
    • Lombardy Region. Social and Health Care Plan. No 937/2010. Milan: Lombardy Region; 2010. Italian. Available at: http://www.sanita.egione.lombardia.it/shared/ccurl/956/366/DGRregole_e_allegati.zip. Accessed June 10, 2012.
    • (2010) Social and Health Care Plan
  • 13
    • 84891084607 scopus 로고    scopus 로고
    • Lombardy Region, [Therapeutic and diagnostic path (PDT) for the patient with HIV/AIDS disease]. Decree no 7485, August 5, 2011. Milan: Lombardy Region; 2012. Italian. Available at, Accessed June 10
    • Lombardy Region. Approvazione del documento avente peroggetto Percorso Diagnostico Terapeutico (PDT) per il paziente affetto da malattia HIV/AIDS [Therapeutic and diagnostic path (PDT) for the patient with HIV/AIDS disease]. Decree no 7485, August 5, 2011. Milan: Lombardy Region; 2012. Italian. Available at: http://www.sanita.regione.lombardia.it/cs/Satellite?c=Page&childpagename=DG_Sanita/Page/NormativaDetail&pagename=DG_SANWrapper&cid=1213275902673&keyid=3520. Accessed June 10, 2012.
    • (2012) Approvazione Del Documento Avente Peroggetto Percorso Diagnostico Terapeutico (PDT) Per Il Paziente Affetto Da Malattia HIV/AIDS
  • 14
    • 84891080233 scopus 로고    scopus 로고
    • Negoziazione e rimborsabilitá [Negotiation and reimbursement; web page on the Internet]. Rome: AIFA; 2013. Italian. Available at, Accessed November 13
    • Agenzia Italiana del Faramco [AIFA; Italian Drug Agency]. Negoziazione e rimborsabilitá [Negotiation and reimbursement; web page on the Internet]. Rome: AIFA; 2013. Italian. Available at: http://www.agenziafarmaco.gov.it/it/content/negoziazione-e-rimborsabilit%C3%A0. Accessed November 13, 2011.
    • (2011) Agenzia Italiana Del Faramco [AIFA; Italian Drug Agency]
  • 15
    • 84891061024 scopus 로고    scopus 로고
    • Istat, [Consumer Price Index for inflation adjustments]. Roma: Istituto nazionale di statistica. Available from, Accessed November 7
    • Istat. Indice dei prezzi al consumo per le rivalutazioni monetarie [Consumer Price Index for inflation adjustments]. Roma: Istituto nazionale di statistica. Available from: http://www.istat.it/it/archivio/30440. Accessed November 7, 2013.
    • (2013) Indice Dei Prezzi Al Consumo Per Le Rivalutazioni Monetarie
  • 16
    • 49849083780 scopus 로고    scopus 로고
    • Analysis of survival in HIV-infected subjects according to socio-economic resources in the HAART era
    • Liotta G, Caleo GM, Mancinelli S. Analysis of survival in HIV-infected subjects according to socio-economic resources in the HAART era. Ann Ig. 2008;20(2):95-104.
    • (2008) Ann Ig , vol.20 , Issue.2 , pp. 95-104
    • Liotta, G.1    Caleo, G.M.2    Mancinelli, S.3
  • 17
    • 78650717778 scopus 로고    scopus 로고
    • Cost effectiveness of darunavir/ritonavir 600/100 mg bid in protease inhibitor-experienced, HIV-1-infected adults in Belgium, Italy, Sweden and the UK
    • Moeremans K, Annemans L, Löthgren M, et al. Cost effectiveness of darunavir/ritonavir 600/100 mg bid in protease inhibitor-experienced, HIV-1-infected adults in Belgium, Italy, Sweden and the UK. Pharmacoeconomics. 2010;28 Suppl 1:107-128.
    • (2010) Pharmacoeconomics , vol.28 , Issue.1 , pp. 107-128
    • Moeremans, K.1    Annemans, L.2    Löthgren, M.3
  • 19
    • 84875317147 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of HIV treatment in the clinical practice of a public hospital in northern Italy
    • Rizzardini G, Bonfanti P, Carenzi L, et al. Cost-effectiveness analysis of HIV treatment in the clinical practice of a public hospital in northern Italy. Ther Clin Risk Manag. 2012;8:377-384.
    • (2012) Ther Clin Risk Manag , vol.8 , pp. 377-384
    • Rizzardini, G.1    Bonfanti, P.2    Carenzi, L.3
  • 20
    • 84874516808 scopus 로고    scopus 로고
    • Cost-utility analysis of lopinavir/ritonavir versus atazanavir + ritonavir administered as first-line therapy for the treatment of HIV infection in Italy: From randomised trial to real world
    • Foglia E, Bonfanti P, Rizzardini G, et al. Cost-utility analysis of lopinavir/ritonavir versus atazanavir + ritonavir administered as first-line therapy for the treatment of HIV infection in Italy: from randomised trial to real world. PLoS One. 2013;8(2):e57777.
    • (2013) PLoS One , vol.8 , Issue.2
    • Foglia, E.1    Bonfanti, P.2    Rizzardini, G.3
  • 21
    • 79959759807 scopus 로고    scopus 로고
    • The cost of HIV disease in Northern Italy: The payer's perspective
    • Rizzardini G, Restelli U, Bonfanti P, et al. The cost of HIV disease in Northern Italy: the payer's perspective. J Acquir Immune Defic Syndr. 2011;57(3):211-217.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , Issue.3 , pp. 211-217
    • Rizzardini, G.1    Restelli, U.2    Bonfanti, P.3
  • 22
    • 84866054720 scopus 로고    scopus 로고
    • Cost of human immunodeficiency virus infection in Italy, 2007-2009: Effective and expensive, are the new drugs worthwhile?
    • Rizzardini G, Restelli U, Bonfanti P, et al. Cost of human immunodeficiency virus infection in Italy, 2007-2009: effective and expensive, are the new drugs worthwhile? Clinicoecon Outcomes Res. 2012;4:245-252.
    • (2012) Clinicoecon Outcomes Res , vol.4 , pp. 245-252
    • Rizzardini, G.1    Restelli, U.2    Bonfanti, P.3
  • 23
    • 9144267049 scopus 로고    scopus 로고
    • Cost-effectiveness of lopinavir/ritonavir versus nelfinavir as the first line highly active antiretroviral therapy regimen for HIV infection
    • Simpson KN, Luo MP, Chumney E, Sun E, Brun S, Ashraf T. Cost-effectiveness of lopinavir/ritonavir versus nelfinavir as the first line highly active antiretroviral therapy regimen for HIV infection. HIV Clin Trials. 2004;5(5):294-304.
    • (2004) HIV Clin Trials , vol.5 , Issue.5 , pp. 294-304
    • Simpson, K.N.1    Luo, M.P.2    Chumney, E.3    Sun, E.4    Brun, S.5    Ashraf, T.6
  • 24
    • 84873935810 scopus 로고    scopus 로고
    • Antiretroviral therapy in HIV-infected patients: A proposal to assess the economic value of the single-tablet regimen
    • Colombo GL, Di Matteo S, Maggiolo F. Antiretroviral therapy in HIV-infected patients: a proposal to assess the economic value of the single-tablet regimen. Clinicoecon Outcomes Res. 2013;5:59-68.
    • (2013) Clinicoecon Outcomes Res , vol.5 , pp. 59-68
    • Colombo, G.L.1    Di Matteo, S.2    Maggiolo, F.3
  • 25
    • 84862147082 scopus 로고    scopus 로고
    • Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons
    • Italian HIV Guidelines Working Group
    • Antinori A, Marcotullio S, Ammassari A, et al; Italian HIV Guidelines Working Group. Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. Update 2011. New Microbiol. 2012;35(2):113-159.
    • (2012) Update 2011. New Microbiol , vol.35 , Issue.2 , pp. 113-159
    • Antinori, A.1    Marcotullio, S.2    Ammassari, A.3
  • 26
    • 0242529051 scopus 로고    scopus 로고
    • Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral naïve patients
    • D'Arminio Monforte A, Lepri AC, Rezza G, et al. Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral naïve patients. I.CO.N.A. Study Group. Italian Cohort of Antiretroviral-Patients. AIDS. 2000;14(5):499-507.
    • (2000) AIDS , vol.14 , Issue.5 , pp. 499-507
    • D'Arminio, M.A.1    Lepri, A.C.2    Rezza, G.3
  • 27
    • 0034604276 scopus 로고    scopus 로고
    • Adherence to protease inhibitor therapy and outcomes in patients with HIV infection
    • Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133(1):21-30.
    • (2000) Ann Intern Med , vol.133 , Issue.1 , pp. 21-30
    • Paterson, D.L.1    Swindells, S.2    Mohr, J.3
  • 28
    • 0035876041 scopus 로고    scopus 로고
    • Non-adherence to highly active antiretroviral therapy predicts progression to AIDS
    • Bangsberg DR, Perry S, Charlebois ED, et al. Non-adherence to highly active antiretroviral therapy predicts progression to AIDS. AIDS. 2001;15(9):1181-1183.
    • (2001) AIDS , vol.15 , Issue.9 , pp. 1181-1183
    • Bangsberg, D.R.1    Perry, S.2    Charlebois, E.D.3
  • 29
    • 65449153627 scopus 로고    scopus 로고
    • The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time
    • Lima VD, Harrigan R, Bangsberg DR, et al. The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. J Acquir Immune Defic Syndr. 2009;50(5): 529-536.
    • (2009) J Acquir Immune Defic Syndr , vol.50 , Issue.5 , pp. 529-536
    • Lima, V.D.1    Harrigan, R.2    Bangsberg, D.R.3
  • 30
    • 2342441340 scopus 로고    scopus 로고
    • Relative prognostic value of self-reported adherence and plasma NNRTI/PI concentrations to predict virological rebound in patients initially responding to HAART
    • AdICoNA Study Group
    • Antinori A, Cozzi-Lepri A, Ammassari A, et al; AdICoNA Study Group. Relative prognostic value of self-reported adherence and plasma NNRTI/PI concentrations to predict virological rebound in patients initially responding to HAART. Antivir Ther. 2004;9(2): 291-296.
    • (2004) Antivir Ther , vol.9 , Issue.2 , pp. 291-296
    • Antinori, A.1    Cozzi-Lepri, A.2    Ammassari, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.