A novel liposomal nanomedicine for nitric oxide delivery and breast cancer treatment

Bio-Medical Materials and Engineering

Volumn 24, Issue 1, 2014, Pages 61-67

  Lee, Soo Yeon ^a   Rim, Yonghoon ^a   McPherson, David D ^a   Huang, Shao Ling ^a   Kim, Hyunggun ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

breast cancer; drug delivery system; liposome; Nanomedicine; nitric oxide

Indexed keywords

BREAST CANCER; BREAST CANCER TREATMENT; CANCER CELL APOPTOSIS; DRUG DELIVERY SYSTEM; ECHOGENIC LIPOSOMES; ENDOGENOUS SIGNALING; GAS DELIVERY SYSTEM; THERAPEUTIC EFFECTS;

BIOMEDICAL ENGINEERING; BIOTECHNOLOGY; CELL DEATH; CYTOTOXICITY; DRUG DELIVERY; LIPOSOMES; MEDICAL NANOTECHNOLOGY; NITRIC OXIDE;

DISEASES;

MANNITOL; NITRIC OXIDE;

ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER CELL CULTURE; CANCER THERAPY; CELL DEATH; CELL VIABILITY; CONFERENCE PAPER; CYTOTOXICITY; DRUG DELIVERY SYSTEM; FREEZING; LIPID COMPOSITION; LIPOSOMAL DELIVERY; NANOMEDICINE; PRIORITY JOURNAL;

BREAST CANCER; DRUG DELIVERY SYSTEM; LIPOSOME; NANOMEDICINE; NITRIC OXIDE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; LIPIDS; LIPOSOMES; MANNITOL; NANOPARTICLES; NITRIC OXIDE; PRESSURE; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

EID: 84891054626     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-130784     Document Type: Conference Paper

References (15)

1. A. Jemal, R. Siegel, J. Xu and E. Ward, Cancer statistics, 2010, CA Cancer J Clin 60 (2010), 277-300.
2. J.A. Sparano, A.N. Makhson, V.F. Semiglazov, S.A. Tjulandin, O.I. Balashova, I.N. Bondarenko, N.V. Bogdanova, G.M. Manikhas, G.P. Oliynychenko, V.A. Chatikhine, S.H. Zhuang, L. Xiu, Z. Yuan and W.R. Rackoff, Pegylated liposomal doxorubicin plus docetaxel significantly improves time to progression without additive cardiotoxicity compared with docetaxel monotherapy in patients with advanced breast cancer previously treated with neoadjuvant-adjuvant anthracycline therapy: Results from a randomized phase III study, J Clin Oncol 27 (2009), 4522-4529.
3. J.A. Sparano and E.P. Winer, Liposomal anthracyclines for breast cancer, Semin Oncol 28 (2001), 32-40.
4. J.W. Park, Liposome-based drug delivery in breast cancer treatment, Breast Cancer Res 4 (2002), 95-99.
5. P. Sonveaux, B.F. Jordan, B. Gallez and O. Feron, Nitric oxide delivery to cancer: why and how, Eur J Cancer 45 (2009), 1352-1369.
6. S. Mocellin, V. Bronte and D. Nitti, Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities, Med Res Rev 27 (2007), 317-352.
7. J.A. Coulter, H.O. McCarthy, J. Xiang, W. Roedl, E. Wagner, T. Robson and D.G. Hirst, Nitric oxide-a novel therapeutic for cancer, Nitric Oxide 19 (2008), 192-198.
8. D. Hirst and T. Robson, Targeting nitric oxide for cancer therapy, J Pharm Pharmacol 59 (2007), 3-13.
9. B. Bonavida, S. Khineche, S. Huerta-Yepez and H. Garban, Therapeutic potential of nitric oxide in cancer, Drug Resist Updat 9 (2006), 157-173.
10. S.L. Huang, Ultrasound-responsive liposomes, Methods Mol Biol 605 (2010), 113-128.
11. C.R. Dass and P.F. Choong, Selective gene delivery for cancer therapy using cationic liposomes: In vivo proof of applicability, J Control Release 113 (2006), 155-163.
12. S.L. Huang, Liposomes in ultrasonic drug and gene delivery, Adv Drug Deliv Rev 60 (2008), 1167-1176.
13. S.L. Huang, P.H. Kee, H. Kim, M.R. Moody, S.M. Chrzanowski, R.C. Macdonald and D.D. McPherson, Nitric oxideloaded echogenic liposomes for nitric oxide delivery and inhibition of intimal hyperplasia, J Am Coll Cardiol 54 (2009), 652-659.
14. K.D. Buchanan, S. Huang, H. Kim, R.C. Macdonald and D.D. McPherson, Echogenic liposome compositions for increased retention of ultrasound reflectivity at physiologic temperature, J Pharm Sci 97 (2008), 2242-2249.
15. S. Huang, A.J. Hamilton, S.D. Tiukinhoy, A. Nagaraj, B.J. Kane, M. Klegerman, D.D. McPherson and R.C. MacDonald, Liposomes as ultrasound imaging contrast agents and as ultrasound-sensitive drug delivery agents, Cell Mol Biol Lett 7 (2002), 233-235.