Factorial experimental design for the culture of human embryonic stem cells as aggregates in stirred suspension bioreactors reveals the potential for interaction effects between bioprocess parameters

Tissue Engineering - Part C: Methods

Volumn 20, Issue 1, 2014, Pages 76-89

  Hunt, Megan M ^a   Meng, Guoliang ^a   Rancourt, Derrick E ^a   Gates, Ian D ^a   Kallos, Michael S ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOREACTORS; CELL CULTURE; DESIGN OF EXPERIMENTS; OPTIMIZATION;

EXPONENTIAL GROWTH RATES; FACTORIAL EXPERIMENT; FACTORIAL EXPERIMENTAL DESIGN; HUMAN EMBRYONIC STEM CELLS; LARGE-SCALE CULTURES; PERFORMANCE INDICATORS; STEPWISE OPTIMIZATION; SUSPENSION CULTURES;

AGGREGATES;

BIOCHEMICAL MARKER;

ARTICLE; BIOPROCESS; CELL AGGREGATION; CELL DENSITY; CELL DIFFERENTIATION; EMBRYO; EMBRYONIC STEM CELL; FACTORIAL DESIGN; GROWTH RATE; HUMAN; HUMAN CELL; INOCULATION; KARYOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCIBILITY; STEM CELL EXPANSION; STIRRED REACTOR; SUSPENSION CELL CULTURE;

ANALYSIS OF VARIANCE; BIOREACTORS; CELL AGGREGATION; CELL COUNT; CELL LINE; CELL PROLIFERATION; CELL SHAPE; EMBRYONIC STEM CELLS; HUMANS; KARYOTYPING; PLURIPOTENT STEM CELLS; RESEARCH DESIGN; SUSPENSIONS;

EID: 84890957899     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2013.0040     Document Type: Article

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