Synthesis and characterization of oligodeoxyribonucleotides modified with 2′-amino-α-l-LNA adenine monomers: High-affinity targeting of single-stranded DNA

Journal of Organic Chemistry

Volumn 78, Issue 24, 2013, Pages 12690-12702

  Andersen, Nicolai K ^a   Anderson, Brooke A ^b   Wengel, Jesper ^a   Hrdlicka, Patrick J ^b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b UNIVERSITY OF IDAHO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION AND FLUORESCENCE SPECTROSCOPY; BINDING SPECIFICITIES; BIOPHYSICAL CHARACTERIZATION; ENZYMATIC STABILITY; LOCKED NUCLEIC ACID; NUCLEOPHILIC SUBSTITUTIONS; SINGLE-STRANDED DNA; SYNTHESIS AND CHARACTERIZATIONS;

DNA; FLUORESCENCE SPECTROSCOPY; OLIGONUCLEOTIDES; PYRENE;

MONOMERS;

2' AMINO ALPHA L LOCKED NUCLEIC ACID ADENIE MONOMER; LOCKED NUCLEIC ACID; MONOMER; OLIGODEOXYRIBONUCLEOTIDE; PHOSPHORAMIDOUS ACID; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ARTICLE; DEACYLATION; DENATURATION; FLUORESCENCE SPECTROSCOPY; GENE TARGETING; GLYCOSYLATION; SYNTHESIS;

ADENINE; DNA, SINGLE-STRANDED; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES;

EID: 84890947688     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo4022937     Document Type: Article

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