Bone marrow cell mobilization by the systemic use of granulocyte colony-stimulating factor (GCSF) improves wound bed preparation

International Journal of Lower Extremity Wounds

Volumn 12, Issue 4, 2013, Pages 256-264

  Iwamoto, Satori ^a   Lin, Xiaofeng ^a   Ramirez, Ron ^a   Carson, Polly ^a   Fiore, David ^a   Goodrich, Jane ^a   Yufit, Tatyana ^a   Falanga, Vincent ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chronic wounds; granulocyte colony stimulating factor (GCSF); leg ulcers; stem cells; wound bed preparation; wound healing

Indexed keywords

COLLAGEN; GRANULOCYTE COLONY STIMULATING FACTOR; GREEN FLUORESCENT PROTEIN; PEGYLATED GRANULOCYTE COLONY STIMULATING FACTOR; POLYVINYL ALCOHOL SPONGE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SODIUM CHLORIDE; STEM CELL ANTIGEN 1; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL IMAGING SYSTEM; ANIMAL MODEL; ARTICLE; ASSAY; CASE REPORT; CELL HOMING; CHIMERA; CHRONIC WOUND; COLONY FORMING CELL; COMPRESSION; CONTROLLED STUDY; DRUG FORMULATION; DRUG MEGADOSE; EPITHELIZATION; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; LEUKOCYTE; LOW DRUG DOSE; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SINGLE DRUG DOSE; STEM CELL MOBILIZATION; SYSTEMIC THERAPY; TAIL; THERAPY; TREATMENT DURATION; ULCER; ULCER HEALING; WOUND CARE; WOUND CLOSURE; WOUND HEALING;

CHRONIC WOUNDS; GRANULOCYTE COLONY-STIMULATING FACTOR (GCSF); LEG ULCERS; STEM CELLS; WOUND BED PREPARATION; WOUND HEALING;

ANIMALS; BONE MARROW CELLS; DIABETIC FOOT; DISEASE MODELS, ANIMAL; DRUG MONITORING; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MIDDLE AGED; TREATMENT OUTCOME; VARICOSE ULCER; WOUND HEALING;

EID: 84890911797     PISSN: 15347346     EISSN: 15526941     Source Type: Journal    
DOI: 10.1177/1534734613513401     Document Type: Article

References (19)

1. Falanga V, Iwamoto S, Chartier M, et al. Autologous bone marrow-derived cultured mesenchymal stem cells delivered in a fibrin spray accelerate healing in murine and human cutaneous wounds. Tissue Eng. 2007 ; 13: 1299-1312
2. Greenbaum AM, Link DC. Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization. Leukemia. 2011 ; 25: 211-217
3. Zhai Y, Zhao Y, Lei J, Su Z, Ma G. Enhanced circulation half-life of site-specific PEGylated rhG-CSF: optimization of PEG molecular weight. J Biotechnol. 2009 ; 142: 259-266
4. Falanga V, Schrayer D, Cha J, et al. Full-thickness wounding of the mouse tail as a model for delayed wound healing: accelerated wound closure in Smad3 knock-out mice. Wound Repair Regen. 2004 ; 12: 320-326
5. Grigg AP, Roberts AW, Raunow H, et al. Optimizing dose and scheduling of filgrastim (granulocyte colony-stimulating factor) for mobilization and collection of peripheral blood progenitor cells in normal volunteers. Blood. 1995 ; 86: 4437-4445
6. Baskiewicz-Halasa M, Pius E, Halasa M, Dziedziejko V, Grymula K, Machalinski B. Different strategies of mixed chimerism induction may determine stem/progenitor cell populations in recipient mice. Transpl Immunol. 2012 ; 26: 34-41
7. McNiece IK, Stewart FM, Deacon DM, et al. Detection of a human CFC with a high proliferative potential. Blood. 1989 ; 74: 609-612
8. Louis SA, Rietze RL, Deleyrolle L, et al. Enumeration of neural stem and progenitor cells in the neural colony-forming cell assay. Stem Cells. 2008 ; 26: 988-996
9. Nakahata T, Ogawa M. Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies. Proc Natl Acad Sci U S A. 1982 ; 79: 3843-3847
10. Deskins DL, Ardestani S, Young PP. The polyvinyl alcohol sponge model implantation. J Vis Exp. 2012 ; 62 :
11. Wiedermann FJ, Mayr AJ, Hobisch-Hagen P, Fuchs D, Schobersberger W. Association of endogenous G-CSF with anti-inflammatory mediators in patients with acute respiratory distress syndrome. J Interferon Cytokine Res. 2003 ; 23: 729-736
12. Tao H, Ma DDF. Evidence for transdifferentiation of human bone marrow-derived stem cells: recent progress and controversies. Pathology. 2003 ; 35: 6-13
13. Phinney DG, Prockop DJ. Mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair - current views. Stem Cells. 2007 ; 25: 2896-2902
14. Templin C, Grote K, Schledzewski K, et al. Ex vivo expanded haematopoietic progenitor cells improve dermal wound healing by paracrine mechanisms. Exp Dermatol. 2009 ; 18: 445-453
15. Kunter U, Rong S, Djuric Z, et al. Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis. J Am Soc Nephrol. 2006 ; 17: 2202-2212
16. Chen L, Tredget EE, Wu PYG, Wu Y. Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS One. 2008 ; 3: e1886
17. Tatsumi K, Otani H, Sato D, et al. Granulocyte-colony stimulating factor increases donor mesenchymal stem cells in bone marrow and their mobilization into peripheral circulation but does not repair dystrophic heart after bone marrow transplantation. Circ J. 2008 ; 72: 1351-1358
18. Sovalat H, Scrofani M, Eidenschenk A, Pasquet S, Rimelen V, Henon P. Identification and isolation from either adult human bone marrow or G-CSF-mobilized peripheral blood of CD34(+)/CD133(+)/CXCR4(+)/Lin(-)CD45(-) cells, featuring morphological, molecular, and phenotypic characteristics of very small embryonic-like (VSEL) stem cells. Exp Hematol. 2011 ; 39: 495-505
19. Sykova E, Jendelova P. In vivo tracking of stem cells in brain and spinal cord injury. Prog Brain Res. 2007 ; 161: 367-383