Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair

Toxicology and Applied Pharmacology

Volumn 274, Issue 2, 2014, Pages 313-318

  Sun, Xi ^a   Zhou, Xixi ^a   Du, Libo ^b   Liu, Wenlan ^a   Liu, Yang ^b   Hudson, Laurie G ^a   Liu, Ke Jian ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b INSTITUTE OF CHEMISTRY   (China)

Author keywords

Arsenite; DNA damage repair; PARP 1; Zinc deficiency; Zinc finger

Indexed keywords

ARSENIC TRIOXIDE; DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; ZINC;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; BIOLOGICAL ACTIVITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA REPAIR; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FLUORESCENCE; HUMAN; HUMAN CELL; HYPOTHESIS; MEMBRANE PERMEABILITY; MOLECULAR RECOGNITION; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SUPPLEMENTATION; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROSCOPY; ZINC DEFICIENCY;

EID: 84890889623     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.11.010     Document Type: Article

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