Isoproterenol effects evaluated in heart slices of human and rat in comparison to rat heart in vivo

Toxicology and Applied Pharmacology

Volumn 274, Issue 2, 2014, Pages 302-312

  Herrmann, Julia E ^a   Heale, Jason ^a   Bieraugel, Mike ^a   Ramos, Meg ^a   Fisher, Robyn L ^b   Vickers, Alison E M ^a  

^a ALLERGAN INC   (United States)

^b Vitron Inc   (United States)

Author keywords

Cardiac injury; Gene and protein pathways; Human heart slices; Isoproterenol; Rat heart in vivo; Rat heart slices

Indexed keywords

FATTY ACID; GROWTH FACTOR; HEAT SHOCK PROTEIN 70; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; ISOPRENALINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 3; PLASMINOGEN ACTIVATOR INHIBITOR 1; REGENERATING ISLET DERIVED 3 BETA PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TROPONIN I; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDITIS; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECT; ENERGY CONSUMPTION; EX VIVO STUDY; FATTY ACID METABOLISM; HEART INJURY; HEART MUSCLE FIBROSIS; HEART MUSCLE NECROSIS; HEART STRESS; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MALE; MIDDLE AGED; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TISSUE SLICE; UPREGULATION; YOUNG ADULT;

EID: 84890869424     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.11.011     Document Type: Article

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