A high-throughput assay to identify modifiers of premature chromosome condensation

Journal of Biomolecular Screening

Volumn 19, Issue 1, 2014, Pages 176-183

  Adams, Matthew ^a   Cookson, Victoria J ^b   Higgins, Julie ^a   Martin, Heather L ^a   Tomlinson, Darren C ^a   Bond, Jacquelyn ^a,b   Morrison, Ewan E ^a,b   Bell, Sandra M ^a,b  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

MCPH1; premature chromosome condensation; reverse genetics; screen

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CAPG 2 PROTEIN; CAPH 2 PROTEIN; CONDENSIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL COUNT; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CHROMOSOME CONDENSATION; CONTROLLED STUDY; FLUORESCENCE IMAGING; GENE; GENE FUNCTION; GENE SILENCING; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MCPH 1 GENE; PHENOTYPE; PREMATURE CHROMOSOME CONDENSATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE GENETICS;

MCPH1; PREMATURE CHROMOSOME CONDENSATION; REVERSE GENETICS; SCREEN;

CELL LINE, TUMOR; CHROMOSOMES; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR IMAGING; REPRODUCIBILITY OF RESULTS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84890848365     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113495443     Document Type: Article

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