Cytotoxic effects of procyanidins from Castanea mollissima Bl. shell on human hepatoma G2 cells in vitro

Food and Chemical Toxicology

Volumn 64, Issue , 2014, Pages 166-176

  Zhang, H ^a   Ke, J ^a   Shao, T ^a   Li, J ^a   Duan, Y ^a   He, Y ^a   Zhang, C ^a   Chen, G ^b   Sun, G ^c   Sun, X ^c  

^a JIANGSU UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Chestnut shell; HepG2 cells; Procyanidins; ROS

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DIMER; MONOMER; POLYMER; PROCYANIDIN; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRIMER; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN HEPG2; CHESTNUT; COLONY FORMATION; CYTOSOLIC FRACTION; DNA FRAGMENTATION; DRUG CYTOTOXICITY; ELECTROSPRAY MASS SPECTROMETRY; FLOW CYTOMETRY; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR WEIGHT; OXIDATIVE STRESS; POLYMERIZATION; WESTERN BLOTTING;

CASTANEA MOLLISSIMA;

(HYDROXYMETHYL) AMINOMETHANE; 2,7-DICHLOROFLUORESCEIN; 2′,7′-DICHLOROFLUORESCEIN DIACETATE; 4′, 6-DIAMIDINE-2′-PHENYLINDOLE DIHYDROCHLORIDE; ACRIDINE ORANGE; AO; APOPTOSIS; CCL(4); CHESTNUT SHELL; CSPC; DAPI; DCF; DCFH-DA; DIMETHYL SULPHOXIDE; DL-DITHIOTHREITOL; DMEM; DMSO; DTT; DULBECCO'S MODIFIED EAGLES MEDIUM; EB; EDTA; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; ESI-MS; ETHIDIUM BROMIDE; ETHYLENEDIAMINE TETRAACETIC ACID; FCS; FETAL CALF SERUM; HCC; HEPATOCELLULAR CARCINOMA; HEPATOMA G2; HEPG2; HEPG2 CELLS; HFD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH-FAT DIET; HPLC; LC-ESI-MS; LIQUID CHROMATOGRAPHY ELECTROSPRAY IONIZATION MASS SPECTROMETRY; MALONDIALDEHYDE; MDA; METHYTHIAZOLETETRAZOLIUM; MTT; NONYLPHENOL POLYOXYETHYLENE ETHER; NP40; PBS; PHOSPHATE BUFFERED SOLUTION; PI; PROCYANIDINS; PROCYNADINS FROM CHESTNUT SHELL; PROPIDIUM IODIDE; REACTIVE OXIDATIVE SPECIES; REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RIBONUCLEASE; RNASE; ROS; RP-HPLC; T-BHP; TERT-BUTYL HYDROPEROXIDE; TETRACHLORIDE; TRIS;

APOPTOSIS; CASPASES; CHROMATOGRAPHY, LIQUID; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; FAGACEAE; HEP G2 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NECROSIS; PLANT EXTRACTS; PROANTHOCYANIDINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84890842582     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.11.026     Document Type: Article

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