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Volumn 20, Issue 1, 2014, Pages 35-42

Interleukin-12p40 in the spinal fluid as a biomarker for clinically isolated syndrome

Author keywords

biological markers; cerebrospinal fluid; clinically isolated syndrome; immunology; interleukin 12 subunit p40; Multiple sclerosis

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 12P40; EOTAXIN; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; LYMPHOTOXIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; NERVE GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; RANTES; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84890813415     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458513491166     Document Type: Article
Times cited : (12)

References (19)
  • 1
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
    • Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol. 2011 ; 69: 292-302
    • (2011) Ann Neurol , vol.69 , pp. 292-302
    • Ch, P.1    Reingold, S.C.2    Banwell, B.3
  • 2
    • 59249105170 scopus 로고    scopus 로고
    • Differential diagnosis of suspected multiple sclerosis: A consensus approach
    • Miller DH, Weinshenker BG, Filippi M, et al. Differential diagnosis of suspected multiple sclerosis: A consensus approach. Mult Scler. 2008 ; 14: 1157-1174
    • (2008) Mult Scler , vol.14 , pp. 1157-1174
    • Miller, D.H.1    Weinshenker, B.G.2    Filippi, M.3
  • 3
    • 84863572660 scopus 로고    scopus 로고
    • "undiagnosing" multiple sclerosis: The challenge of misdiagnosis in MS
    • Solomon AJ, Klein EP, Bourdette D. "Undiagnosing" multiple sclerosis: The challenge of misdiagnosis in MS. Neurology. 2012 ; 78: 1986-1991
    • (2012) Neurology , vol.78 , pp. 1986-1991
    • Solomon, A.J.1    Klein, E.P.2    Bourdette, D.3
  • 4
    • 81055156291 scopus 로고    scopus 로고
    • The radiologically isolated syndrome: Look (again) before you treat
    • Spain R, Bourdette D. The radiologically isolated syndrome: Look (again) before you treat. Curr Neurol Neurosci Rep. 2011 ; 11: 498-506
    • (2011) Curr Neurol Neurosci Rep , vol.11 , pp. 498-506
    • Spain, R.1    Bourdette, D.2
  • 5
    • 77249098682 scopus 로고    scopus 로고
    • Analyses of cerebrospinal fluid in the diagnosis and monitoring of multiple sclerosis
    • Awad A, Hemmer B, Hartung HP, et al. Analyses of cerebrospinal fluid in the diagnosis and monitoring of multiple sclerosis. J Neuroimmunol. 2010 ; 219: 1-7
    • (2010) J Neuroimmunol , vol.219 , pp. 1-7
    • Awad, A.1    Hemmer, B.2    Hartung, H.P.3
  • 6
    • 28544436950 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2005 revisions to the "mcDonald Criteria"
    • Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol. 2005 ; 58: 840-846
    • (2005) Ann Neurol , vol.58 , pp. 840-846
    • Ch, P.1    Reingold, S.C.2    Edan, G.3
  • 7
    • 84879008841 scopus 로고    scopus 로고
    • Basow DS, ed. MA: UpToDate in Waltham;
    • Johnson KS UpToDate. Basow DS, ed. MA: UpToDate in Waltham ; 2012 :
    • (2012) UpToDate
    • Johnson, K.S.1
  • 8
    • 34147123775 scopus 로고    scopus 로고
    • The natural history of relapses in multiple sclerosis
    • Vollmer T. The natural history of relapses in multiple sclerosis. J Neurol Sci. 2007 ; 256: S5 - S13
    • (2007) J Neurol Sci , vol.256
    • Vollmer, T.1
  • 9
    • 37249035893 scopus 로고    scopus 로고
    • Multiple sclerosis: Relapses and timing of remissions
    • Iuliano G, Napoletano R, Esposito A. Multiple sclerosis: Relapses and timing of remissions. Eur Neurol. 2008 ; 59: 44-48
    • (2008) Eur Neurol , vol.59 , pp. 44-48
    • Iuliano, G.1    Napoletano, R.2    Esposito, A.3
  • 10
    • 0031943618 scopus 로고    scopus 로고
    • The interleukin-12/interleukin-12-receptor system: Role in normal and pathologic immune responses
    • Gately MK, Renzetti LM, Magram J, et al. The interleukin-12/interleukin- 12-receptor system: Role in normal and pathologic immune responses. Annu Rev Immunol. 1998 ; 16: 495-521
    • (1998) Annu Rev Immunol , vol.16 , pp. 495-521
    • Gately, M.K.1    Renzetti, L.M.2    Magram, J.3
  • 11
    • 46749156738 scopus 로고    scopus 로고
    • Role of cytokine p40 family in multiple sclerosis
    • Brahmachari S, Pahan K. Role of cytokine p40 family in multiple sclerosis. Minerva Med. 2008 ; 99: 105-118
    • (2008) Minerva Med , vol.99 , pp. 105-118
    • Brahmachari, S.1    Pahan, K.2
  • 12
    • 69749101475 scopus 로고    scopus 로고
    • The IL-12 family of cytokines in infection, inflammation and autoimmune disorders
    • Gee K, Guzzo C, Che Mat NF, et al. The IL-12 family of cytokines in infection, inflammation and autoimmune disorders. Inflamm Allergy Drug Targets. 2009 ; 8: 40-52
    • (2009) Inflamm Allergy Drug Targets , vol.8 , pp. 40-52
    • Gee, K.1    Guzzo, C.2    Che Mat, N.F.3
  • 13
    • 0036677420 scopus 로고    scopus 로고
    • Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
    • Becher B, Durell BG, Noelle RJ. Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12. J Clin Invest. 2002 ; 110: 493-497
    • (2002) J Clin Invest , vol.110 , pp. 493-497
    • Becher, B.1    Durell, B.G.2    Noelle, R.J.3
  • 14
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
    • Windhagen A, Newcombe J, Dangond F, et al. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J Exp Med. 1995 ; 182: 1985-1996
    • (1995) J Exp Med , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3
  • 15
    • 0032975730 scopus 로고    scopus 로고
    • Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
    • van Boxel-Dezaire AH, Hoff SC, van Oosten BW, et al. Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann Neurol. 1999 ; 45: 695-703
    • (1999) Ann Neurol , vol.45 , pp. 695-703
    • Van Boxel-Dezaire, A.H.1    Hoff, S.C.2    Van Oosten, B.W.3
  • 16
    • 66549113544 scopus 로고    scopus 로고
    • Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70
    • Jana M, Pahan K. Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70. Immunology. 2009 ; 127: 312-325
    • (2009) Immunology , vol.127 , pp. 312-325
    • Jana, M.1    Pahan, K.2
  • 17
    • 59249089569 scopus 로고    scopus 로고
    • IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages
    • Jana M, Pahan K. IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Mol Immunol. 2009 ; 46: 773-783
    • (2009) Mol Immunol , vol.46 , pp. 773-783
    • Jana, M.1    Pahan, K.2
  • 18
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 2000 ; 13: 715-725
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 19
    • 48849087125 scopus 로고    scopus 로고
    • Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study
    • Segal BM, Constantinescu CS, Raychaudhuri A, et al. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol. 2008 ; 7: 796-804
    • (2008) Lancet Neurol , vol.7 , pp. 796-804
    • Segal, B.M.1    Constantinescu, C.S.2    Raychaudhuri, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.