Successful therapeutic transplantation of revertant skin in epidermolysis bullosa

Journal of the American Academy of Dermatology

Volumn 70, Issue 1, 2014, Pages 98-101

  Gostyński, Antoni ^a   Pasmooij, Anna M G ^a   Jonkman, Marcel F ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

junctional epidermolysis bullosa; laminin 332; revertant cell therapy; revertant mosaicism

Indexed keywords

AGED; ARTICLE; CASE REPORT; CONTROLLED STUDY; DNA SEQUENCE; EPIDERMOLYSIS BULLOSA; EPITHELIZATION; FOLLOW UP; GENE; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; KERATINOCYTE; LAMB3 GENE; MALE; PRIORITY JOURNAL; REVERTANT; SKIN BIOPSY; SKIN TRANSPLANTATION; SKIN ULCER;

EID: 84890804638     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2013.08.052     Document Type: Article

References (16)

1. J. Uitto, A.M. Christiano, W.H. McLean, and J.A. McGrath Novel molecular therapies for heritable skin disorders J Invest Dermatol 132 2012 820 828
2. M. Laimer, J.W. Bauer, A. Klausegger, J. Koller, G. Pohla-Gubo, and W. Muss Skin grafting as a therapeutic approach in pretibially restricted junctional epidermolysis bullosa Br J Dermatol 154 2006 185 187
3. T. Hasegawa, Y. Suga, M. Mizoguchi, S. Ikeda, H. Ogawa, and K. Kubo Clinical trial of allogeneic cultured dermal substitute for the treatment of intractable skin ulcers in 3 patients with recessive dystrophic epidermolysis bullosa J Am Acad Dermatol 50 2004 803 804
4. M. Furue, I. Ando, Y. Inoue, K. Tamaki, K. Oohara, and A. Kukita Pretibial epidermolysis bullosa: successful therapy with a skin graft Arch Dermatol 122 1986 310 313
5. D.P. Fivenson, L. Scherschun, M. Choucair, D. Kukuruga, J. Young, and T. Shwayder Graftskin therapy in epidermolysis bullosa J Am Acad Dermatol 48 2003 886 892
6. A.F. Falabella, I.C. Valencia, W.H. Eaglstein, and L.A. Schachner Tissue-engineered skin (Apligraf) in the healing of patients with epidermolysis bullosa wounds Arch Dermatol 136 2000 1225 1230
7. D.M. Carter, A.N. Lin, M.C. Varghese, D. Caldwell, L.A. Pratt, and M. Eisinger Treatment of junctional epidermolysis bullosa with epidermal autografts J Am Acad Dermatol 17 1987 246 250
8. E.E. Betsi, D.F. Kalbermatten, and W. Raffoul Surgical management of dystrophic epidermolysis bullosa with autologous composite cultured skin grafts J Hand Surg Eur Vol 34 2009 398 399
9. W.Y. Yuen, J. Huizinga, and M.F. Jonkman Punch grafting of chronic ulcers in patients with laminin-332-deficient, non-Herlitz junctional epidermolysis bullosa J Am Acad Dermatol 68 2013 93 97 e1-2
10. R. Hirschhorn In vivo reversion to normal of inherited mutations in humans J Med Genet 40 2003 721 728
11. M.F. Jonkman, and A.M. Pasmooij Revertant mosaicism-patchwork in the skin N Engl J Med 360 2009 1680 1682
12. M. Itoh, M. Kiuru, M.S. Cairo, and A.M. Christiano Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells Proc Natl Acad Sci U S A 108 2011 8797 8802
13. J.E. Lai-Cheong, J.A. McGrath, and J. Uitto Revertant mosaicism in skin: natural gene therapy Trends Mol Med 17 2011 140 148
14. A. Gostynski, F.C. Deviaene, A.M. Pasmooij, H.H. Pas, and M.F. Jonkman Adhesive stripping to remove epidermis in junctional epidermolysis bullosa for revertant cell therapy Br J Dermatol 161 2009 444 447
15. W.Y. Yuen, and M.F. Jonkman Risk of squamous cell carcinoma in junctional epidermolysis bullosa, non-Herlitz type: report of 7 cases and a review of the literature J Am Acad Dermatol 65 2011 780 789
16. A.M. Pasmooij, H.H. Pas, M.C. Bolling, and M.F. Jonkman Revertant mosaicism in junctional epidermolysis bullosa due to multiple correcting second-site mutations in LAMB3 J Clin Invest 117 2007 1240 1248