Whole-body SPECT/CT for bone scintigraphy: Diagnostic value and effect on patient management in oncological patients

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 41, Issue 1, 2014, Pages 59-67

  Palmedo, H ^a   Marx, C ^b   Ebert, A ^a   Kreft, B ^a   Ko, Y ^a   Turler A ^a   Vorreuther, R ^c   Gohring U ^a   Schild, H H ^b   Gerhardt, T ^d   Poge U ^d   Ezziddin, S ^b   Biersack, H J ^b   Ahmadzadehfar, H ^b  

^a Johanniter Krankenhaus   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c Waldkrankenhaus Evangelische Kliniken   (Germany)

^d Institute of Internal Medicine Nephrology   (Germany)

Author keywords

Bone metastases; Bone scintigraphy; Breast cancer; Prostate cancer; SPECT CT

Indexed keywords

MEDRONATE TECHNETIUM TC 99M;

ADULT; ARTICLE; BONE METASTASIS; BONE SCINTISCANNING; BREAST CANCER; CANCER PATIENT; CANCER STAGING; CERVICAL SPINE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FEMALE; FOLLOW UP; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; PATIENT CARE; PELVIS; PREDICTIVE VALUE; PROSPECTIVE STUDY; PROSTATE CANCER; RIB; SENSITIVITY AND SPECIFICITY; SHOULDER; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STERNUM; THORACIC SPINE; WHOLE BODY SCINTISCANNING;

BONE AND BONES; BONE NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIMODAL IMAGING; ROC CURVE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED; WHOLE BODY IMAGING;

EID: 84890788032     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-013-2532-6     Document Type: Article

References (18)

1. Horger M, Eschmann SM, Pfannenberg C, Vonthein R, Besenfelder H, Claussen CD, et al. Evaluation of combined transmission and emission tomography for classification of skeletal lesions. AJR Am J Roentgenol. 2004;183(3):655-61.
2. Nomayr A, Romer W, Strobel D, Bautz W, Kuwert T. Anatomical accuracy of hybrid SPECT/spiral CT in the lower spine. Nucl Med Commun. 2006;27(6):521-8.
3. Willowson K, Bailey DL, Baldock C. Quantitative SPECT reconstruction using CT-derived corrections. Phys Med Biol. 2008;53(12):3099-112.
4. Reinartz P, Schaffeldt J, Sabri O, Zimny M, Nowak B, Ostwald E, et al. Benign versus malignant osseous lesions in the lumbar vertebrae: differentiation by means of bone SPET. Eur J Nucl Med. 2000;27(6):721-6.
5. Romer W, Nomayr A, Uder M, Bautz W, Kuwert T. SPECT-guided CT for evaluating foci of increased bone metabolism classified as indeterminate on SPECT in cancer patients. J Nucl Med. 2006;47(7):1102-6.
6. Utsunomiya D, Shiraishi S, Imuta M, Tomiguchi S, Kawanaka K, Morishita S, et al. Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology. 2006;238(1):264-71.
7. Strobel K, Burger C, Seifert B, Husarik DB, Soyka JD, Hany TF. Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol. 2007;188(5):W467-474.
8. Helyar V, Mohan HK, Barwick T, Livieratos L, Gnanasegaran G, Clarke SE, et al. The added value of multislice SPECT/CT in patients with equivocal bony metastasis from carcinoma of the prostate. Eur J Nucl Med Mol Imaging. 2010;37(4):706-13.
9. Zhao Z, Li L, Li F, Zhao L. Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer. Skeletal Radiol. 2010;39(2):147-53.
10. Sharma P, Kumar R, Singh H, Bal C, Julka PK, Thulkar S, et al. Indeterminate lesions on planar bone scintigraphy in lung cancer patients: SPECT, CT or SPECT-CT? Skeletal Radiol. 2012;41(7):843-50.
11. Palmedo H, Bucerius J, Joe A, Strunk H, Hortling N, Meyka S, et al. Integrated PET/CT in differentiated thyroid cancer: diagnostic accuracy and impact on patient management. J Nucl Med. 2006;47(4):616-24.
12. Silvestri GA, Gould MK, Margolis ML, Tanoue LT, McCrory D, Toloza E, et al. Noninvasive staging of non-small cell lung cancer: ACCP evidenced-based clinical practice guidelines (II edition). Chest. 2007;132(3 Suppl):178S-201S.
13. Abuzallouf S, Dayes I, Lukka H. Baseline staging of newly diagnosed prostate cancer: a summary of the literature. J Urol. 2004;171(6 Pt 1):2122-7.
14. Houssami N, Costelloe CM. Imaging bone metastases in breast cancer: evidence on comparative test accuracy. Ann Oncol. 2012;23(4):834-43.
15. Schirrmeister H, Guhlmann A, Kotzerke J, Santjohanser C, Kühn T, Kreienberg R, et al. Early detection and accurate description of extent of metastatic bone disease in breast cancer with fluoride ion and positron emission tomography. J Clin Oncol. 1999;17(8):2381-9.
16. Schirrmeister H, Glatting G, Hetzel J, Nüssle K, Arslandemir C, Buck AK, et al. Prospective evaluation of the clinical value of planar bone scans, SPECT, and (18)F-labeled NaF PET in newly diagnosed lung cancer. J Nucl Med. 2001;42(12):1800-4.
17. Even-Sapir E, Metser U, Mishani E, Lievshitz G, Lerman H, Leibovitch I. The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP planar bone scintigraphy, single- and multi-field-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT. J Nucl Med. 2006;47(2):287-97.
18. Bubendorf L, Schopfer A, Wagner U, Sauter G, Moch H, Willi N, et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol. 2000;31(5):578-83.