-
1
-
-
33846969882
-
A topological mechanism for TRF2-enhanced strand invasion
-
Amiard, S., Doudeau, M., Pinte, S., Poulet, A., Lenain, C., Faivre-Moskalenko, C., et al. (2007). A topological mechanism for TRF2-enhanced strand invasion. Nat. Struct. Mol. Biol. 14, 147-154.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 147-154
-
-
Amiard, S.1
Doudeau, M.2
Pinte, S.3
Poulet, A.4
Lenain, C.5
Faivre-Moskalenko, C.6
-
2
-
-
0033869101
-
A theoretical model for the prediction of sequence-dependent nucleosome thermodynamic stability
-
Anselmi, C., Bocchinfuso, G., De Santis, P., Savino, M., and Scipioni, A. (2000). A theoretical model for the prediction of sequence-dependent nucleosome thermodynamic stability. Biophys. J. 79, 601-613.
-
(2000)
Biophys. J.
, vol.79
, pp. 601-613
-
-
Anselmi, C.1
Bocchinfuso, G.2
De Santis, P.3
Savino, M.4
Scipioni, A.5
-
4
-
-
84866115963
-
Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1alpha
-
Arnoult, N., Van Beneden, A., and Decottignies, A. (2012). Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1alpha. Nat. Struct. Mol. Biol. 19, 948-956.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 948-956
-
-
Arnoult, N.1
Van Beneden, A.2
Decottignies, A.3
-
5
-
-
74049111326
-
Telomeres and telomerase in cancer
-
Artandi, S. E., and DePinho, R. A. (2010). Telomeres and telomerase in cancer. Carcinogenesis 31, 9-18.
-
(2010)
Carcinogenesis
, vol.31
, pp. 9-18
-
-
Artandi, S.E.1
DePinho, R.A.2
-
6
-
-
68349133311
-
Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance
-
Atanassov, B. S., Evrard, Y. A., Multani, A. S., Zhang, Z., Tora, L., Devys, D., et al. (2009). Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Mol. Cell 35, 352-364.
-
(2009)
Mol. Cell
, vol.35
, pp. 352-364
-
-
Atanassov, B.S.1
Evrard, Y.A.2
Multani, A.S.3
Zhang, Z.4
Tora, L.5
Devys, D.6
-
7
-
-
0034994404
-
Human intrachromosomal telomeric-like repeats: sequence organization and mechanisms of origin
-
Azzalin, C. M., Nergadze, S. G., and Giulotto, E. (2001). Human intrachromosomal telomeric-like repeats: sequence organization and mechanisms of origin. Chromosoma 110, 75-82.
-
(2001)
Chromosoma
, vol.110
, pp. 75-82
-
-
Azzalin, C.M.1
Nergadze, S.G.2
Giulotto, E.3
-
8
-
-
37349043972
-
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
-
Azzalin, C. M., Reichenbach, P., Khoriauli, L., Giulotto, E., and Lingner, J. (2007). Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318, 798-801.
-
(2007)
Science
, vol.318
, pp. 798-801
-
-
Azzalin, C.M.1
Reichenbach, P.2
Khoriauli, L.3
Giulotto, E.4
Lingner, J.5
-
9
-
-
84860176464
-
The telomeric transcriptome of Schizosaccharomyces pombe
-
Bah, A., Wischnewski, H., Shchepachev, V., and Azzalin, C. M. (2012). The telomeric transcriptome of Schizosaccharomyces pombe. Nucleic Acids Res. 40, 2995-3005.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2995-3005
-
-
Bah, A.1
Wischnewski, H.2
Shchepachev, V.3
Azzalin, C.M.4
-
10
-
-
0842303305
-
The kinase activity of DNA-PK is required to protect mammalian telomeres
-
Bailey, S. M., Brenneman, M. A., Halbrook, J., Nickoloff, J. A., Ullrich, R. L., and Goodwin, E. H. (2004). The kinase activity of DNA-PK is required to protect mammalian telomeres. DNA Repair (Amst.) 3, 225-233.
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 225-233
-
-
Bailey, S.M.1
Brenneman, M.A.2
Halbrook, J.3
Nickoloff, J.A.4
Ullrich, R.L.5
Goodwin, E.H.6
-
11
-
-
79955402377
-
The telomere binding protein TRF2 induces chromatin compaction
-
doi:10.1371/journal.pone.0019124
-
Baker, A. M., Fu, Q., Hayward, W., Victoria, S., Pedroso, I. M., Lindsay, S. M., et al. (2011). The telomere binding protein TRF2 induces chromatin compaction. PLoS ONE 6:e19124. doi:10.1371/journal.pone.0019124
-
(2011)
PLoS ONE
, vol.6
-
-
Baker, A.M.1
Fu, Q.2
Hayward, W.3
Victoria, S.4
Pedroso, I.M.5
Lindsay, S.M.6
-
12
-
-
84867304481
-
The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures
-
Barefield, C., and Karlseder, J. (2012). The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures. Nucleic Acids Res. 40, 7358-7367.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 7358-7367
-
-
Barefield, C.1
Karlseder, J.2
-
13
-
-
84868118733
-
Cockayne syndrome group B protein interacts with TRF2 and regulates telomere length and stability
-
Batenburg, N. L., Mitchell, T. R., Leach, D. M., Rainbow, A. J., and Zhu, X. D. (2012). Cockayne syndrome group B protein interacts with TRF2 and regulates telomere length and stability. Nucleic Acids Res. 40, 9661-9674.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 9661-9674
-
-
Batenburg, N.L.1
Mitchell, T.R.2
Leach, D.M.3
Rainbow, A.J.4
Zhu, X.D.5
-
14
-
-
77955843922
-
Pot1 and telomere maintenance
-
Baumann, P., and Price, C. (2010). Pot1 and telomere maintenance. FEBS Lett. 584, 3779-3784.
-
(2010)
FEBS Lett.
, vol.584
, pp. 3779-3784
-
-
Baumann, P.1
Price, C.2
-
15
-
-
0029780764
-
Condensation of rat telomere-specific nucleosomal arrays containing unusually short DNA repeats and histone H1
-
Bedoyan, J. K., Lejnine, S., Makarov, V. L., and Langmore, J. P. (1996). Condensation of rat telomere-specific nucleosomal arrays containing unusually short DNA repeats and histone H1. J. Biol. Chem. 271, 18485-18493.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18485-18493
-
-
Bedoyan, J.K.1
Lejnine, S.2
Makarov, V.L.3
Langmore, J.P.4
-
16
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti, R., Garcia-Cao, M., and Blasco, M. A. (2007). Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat. Genet. 39, 243-250.
-
(2007)
Nat. Genet.
, vol.39
, pp. 243-250
-
-
Benetti, R.1
Garcia-Cao, M.2
Blasco, M.A.3
-
17
-
-
51349116001
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
-
Benetti, R., Gonzalo, S., Jaco, I., Munoz, P., Gonzalez, S., Schoeftner, S., et al. (2008a). A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol. 15, 998.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 998
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Munoz, P.4
Gonzalez, S.5
Schoeftner, S.6
-
18
-
-
55849088321
-
Role of TRF2 in the assembly of telomeric chromatin
-
Benetti, R., Schoeftner, S., Munoz, P., and Blasco, M. A. (2008b). Role of TRF2 in the assembly of telomeric chromatin. Cell Cycle 7, 3461-3468.
-
(2008)
Cell Cycle
, vol.7
, pp. 3461-3468
-
-
Benetti, R.1
Schoeftner, S.2
Munoz, P.3
Blasco, M.A.4
-
19
-
-
0242458238
-
Systematic search for compact structures of telomeric nucleosomes
-
Besker, N., Anselmi, C., Paparcone, R., Scipioni, A., Savino, M., and De Santis, P. (2003). Systematic search for compact structures of telomeric nucleosomes. FEBS Lett. 554, 369-372.
-
(2003)
FEBS Lett.
, vol.554
, pp. 369-372
-
-
Besker, N.1
Anselmi, C.2
Paparcone, R.3
Scipioni, A.4
Savino, M.5
De Santis, P.6
-
20
-
-
84863011409
-
TIN2 stability is regulated by the E3 ligase Siah2
-
Bhanot, M., and Smith, S. (2012). TIN2 stability is regulated by the E3 ligase Siah2. Mol. Cell. Biol. 32, 376-384.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 376-384
-
-
Bhanot, M.1
Smith, S.2
-
21
-
-
84875464903
-
Quantitative visualization of DNA G-quadruplex structures in human cells
-
Biffi, G., Tannahill, D., McCafferty, J., and Balasubramanian, S. (2013). Quantitative visualization of DNA G-quadruplex structures in human cells. Nat. Chem. 5, 182-186.
-
(2013)
Nat. Chem.
, vol.5
, pp. 182-186
-
-
Biffi, G.1
Tannahill, D.2
McCafferty, J.3
Balasubramanian, S.4
-
22
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn, E. H. (1991). Structure and function of telomeres. Nature 350, 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
23
-
-
0034597794
-
Telomere states and cell fates
-
Blackburn, E. H. (2000). Telomere states and cell fates. Nature 408, 53-56.
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.H.1
-
24
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E. H. (2001). Switching and signaling at the telomere. Cell 106, 661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
25
-
-
14544277627
-
Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
-
Blackburn, E. H. (2005). Telomeres and telomerase: their mechanisms of action and the effects of altering their functions. FEBS Lett. 579, 859-862.
-
(2005)
FEBS Lett.
, vol.579
, pp. 859-862
-
-
Blackburn, E.H.1
-
26
-
-
33947317206
-
The epigenetic regulation of mammalian telomeres
-
Blasco, M. A. (2007). The epigenetic regulation of mammalian telomeres. Nat. Rev. Genet. 8, 299-309.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 299-309
-
-
Blasco, M.A.1
-
27
-
-
77951978963
-
TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends
-
Bombarde, O., Boby, C., Gomez, D., Frit, P., Giraud-Panis, M. J., Gilson, E., et al. (2010). TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends. EMBO J. 29, 1573-1584.
-
(2010)
EMBO J.
, vol.29
, pp. 1573-1584
-
-
Bombarde, O.1
Boby, C.2
Gomez, D.3
Frit, P.4
Giraud-Panis, M.J.5
Gilson, E.6
-
28
-
-
84855996113
-
G-quadruplexes: from guanine gels to chemotherapeutics
-
Bryan, T. M., and Baumann, P. (2011). G-quadruplexes: from guanine gels to chemotherapeutics. Mol. Biotechnol. 49, 198-208.
-
(2011)
Mol. Biotechnol.
, vol.49
, pp. 198-208
-
-
Bryan, T.M.1
Baumann, P.2
-
29
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan, T. M., Englezou, A., Dalla-Pozza, L., Dunham, M. A., and Reddel, R. R. (1997). Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 3, 1271-1274.
-
(1997)
Nat. Med.
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
30
-
-
67349246601
-
The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage
-
Buscemi, G., Zannini, L., Fontanella, E., Lecis, D., Lisanti, S., and Delia, D. (2009). The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage. Curr. Biol. 19, 874-879.
-
(2009)
Curr. Biol.
, vol.19
, pp. 874-879
-
-
Buscemi, G.1
Zannini, L.2
Fontanella, E.3
Lecis, D.4
Lisanti, S.5
Delia, D.6
-
31
-
-
0031031106
-
In vitro low propensity to form nucleosomes of four telomeric sequences
-
Cacchione, S., Cerone, M. A., and Savino, M. (1997). In vitro low propensity to form nucleosomes of four telomeric sequences. FEBS Lett. 400, 37-41.
-
(1997)
FEBS Lett.
, vol.400
, pp. 37-41
-
-
Cacchione, S.1
Cerone, M.A.2
Savino, M.3
-
32
-
-
80052468708
-
A role for heterochromatin protein 1gamma at human telomeres
-
Canudas, S., Houghtaling, B. R., Bhanot, M., Sasa, G., Savage, S. A., Bertuch, A. A., et al. (2011). A role for heterochromatin protein 1gamma at human telomeres. Genes Dev. 25, 1807-1819.
-
(2011)
Genes Dev.
, vol.25
, pp. 1807-1819
-
-
Canudas, S.1
Houghtaling, B.R.2
Bhanot, M.3
Sasa, G.4
Savage, S.A.5
Bertuch, A.A.6
-
33
-
-
68949141617
-
MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription
-
Caslini, C., Connelly, J. A., Serna, A., Broccoli, D., and Hess, J. L. (2009). MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol. Cell. Biol. 29, 4519-4526.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4519-4526
-
-
Caslini, C.1
Connelly, J.A.2
Serna, A.3
Broccoli, D.4
Hess, J.L.5
-
34
-
-
22144490491
-
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
-
Celli, G. B., and de Lange, T. (2005). DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nat. Cell Biol. 7, 712-718.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 712-718
-
-
Celli, G.B.1
de Lange, T.2
-
35
-
-
33746644257
-
Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
-
Celli, G. B., Denchi, E. L., and De Lange, T. (2006). Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination. Nat. Cell Biol. 8, 885-890.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 885-890
-
-
Celli, G.B.1
Denchi, E.L.2
De Lange, T.3
-
36
-
-
84871937830
-
A three-state model of telomere control over human proliferative boundaries
-
Cesare, A. J., and Karlseder, J. (2012). A three-state model of telomere control over human proliferative boundaries. Curr. Opin. Cell Biol. 24, 731-738.
-
(2012)
Curr. Opin. Cell Biol.
, vol.24
, pp. 731-738
-
-
Cesare, A.J.1
Karlseder, J.2
-
37
-
-
71449119003
-
Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions
-
Cesare, A. J., Kaul, Z., Cohen, S. B., Napier, C. E., Pickett, H. A., Neumann, A. A., et al. (2009). Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions. Nat. Struct. Mol. Biol. 16, 1244-1251.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1244-1251
-
-
Cesare, A.J.1
Kaul, Z.2
Cohen, S.B.3
Napier, C.E.4
Pickett, H.A.5
Neumann, A.A.6
-
38
-
-
0037610123
-
TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres
-
Chang, W., Dynek, J. N., and Smith, S. (2003). TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres. Genes Dev. 17, 1328-1333.
-
(2003)
Genes Dev.
, vol.17
, pp. 1328-1333
-
-
Chang, W.1
Dynek, J.N.2
Smith, S.3
-
39
-
-
84865263603
-
The human CST complex is a terminator of telomerase activity
-
Chen, L. Y., Redon, S., and Lingner, J. (2012). The human CST complex is a terminator of telomerase activity. Nature 488, 540-544.
-
(2012)
Nature
, vol.488
, pp. 540-544
-
-
Chen, L.Y.1
Redon, S.2
Lingner, J.3
-
40
-
-
60549089999
-
Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening
-
Chen, Y. C., Teng, S. C., and Wu, K. J. (2009). Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening. Cancer Invest. 27, 24-28.
-
(2009)
Cancer Invest.
, vol.27
, pp. 24-28
-
-
Chen, Y.C.1
Teng, S.C.2
Wu, K.J.3
-
41
-
-
40749109894
-
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
-
Cokus, S. J., Feng, S., Zhang, X., Chen, Z., Merriman, B., Haudenschild, C. D., et al. (2008). Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 452, 215-219.
-
(2008)
Nature
, vol.452
, pp. 215-219
-
-
Cokus, S.J.1
Feng, S.2
Zhang, X.3
Chen, Z.4
Merriman, B.5
Haudenschild, C.D.6
-
42
-
-
0036132673
-
Role for the related poly(ADP-ribose) polymerases tankyrase 1 and 2 at human telomeres
-
Cook, B. D., Dynek, J. N., Chang, W., Shostak, G., and Smith, S. (2002). Role for the related poly(ADP-ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol. Cell. Biol. 22, 332-342.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 332-342
-
-
Cook, B.D.1
Dynek, J.N.2
Chang, W.3
Shostak, G.4
Smith, S.5
-
43
-
-
0031038170
-
Regulation of telomere length and function by a Myb-domain protein in fission yeast
-
Cooper, J. P., Nimmo, E. R., Allshire, R. C., and Cech, T. R. (1997). Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature 385, 744-747.
-
(1997)
Nature
, vol.385
, pp. 744-747
-
-
Cooper, J.P.1
Nimmo, E.R.2
Allshire, R.C.3
Cech, T.R.4
-
44
-
-
0035822641
-
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
-
d'Adda di Fagagna, F., Hande, M. P., Tong, W. M., Roth, D., Lansdorp, P. M., Wang, Z. Q., et al. (2001). Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr. Biol. 11, 1192-1196.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1192-1196
-
-
d'Adda di Fagagna, F.1
Hande, M.P.2
Tong, W.M.3
Roth, D.4
Lansdorp, P.M.5
Wang, Z.Q.6
-
45
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna, F., Reaper, P. M., Clay-Farrace, L., Fiegler, H., Carr, P., Von Zglinicki, T., et al. (2003). A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194-198.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
-
46
-
-
37049004147
-
Targeting telomeres and telomerase
-
De Cian, A., Lacroix, L., Douarre, C., Temime-Smaali, N., Trentesaux, C., Riou, J. F., et al. (2008). Targeting telomeres and telomerase. Biochimie 90, 131-155.
-
(2008)
Biochimie
, vol.90
, pp. 131-155
-
-
De Cian, A.1
Lacroix, L.2
Douarre, C.3
Temime-Smaali, N.4
Trentesaux, C.5
Riou, J.F.6
-
47
-
-
1842683257
-
T-loops and the origin of telomeres
-
de Lange, T. (2004). T-loops and the origin of telomeres. Nat. Rev. Mol. Cell Biol. 5, 323-329.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 323-329
-
-
de Lange, T.1
-
48
-
-
24944460598
-
Shelterin: the protein complex that shapes and safeguards human telomeres
-
de Lange, T. (2005). Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19, 2100-2110.
-
(2005)
Genes Dev.
, vol.19
, pp. 2100-2110
-
-
de Lange, T.1
-
49
-
-
71149093724
-
How telomeres solve the end-protection problem
-
de Lange, T. (2009). How telomeres solve the end-protection problem. Science 326, 948-952.
-
(2009)
Science
, vol.326
, pp. 948-952
-
-
de Lange, T.1
-
50
-
-
58149085861
-
Purification of proteins associated with specific genomic loci
-
Dejardin, J., and Kingston, R. E. (2009). Purification of proteins associated with specific genomic loci. Cell 136, 175-186.
-
(2009)
Cell
, vol.136
, pp. 175-186
-
-
Dejardin, J.1
Kingston, R.E.2
-
51
-
-
34548317418
-
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
-
Denchi, E. L., and de Lange, T. (2007). Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 448, 1068-1071.
-
(2007)
Nature
, vol.448
, pp. 1068-1071
-
-
Denchi, E.L.1
de Lange, T.2
-
52
-
-
68949149732
-
Multiple roles for MRE11 at uncapped telomeres
-
Deng, Y., Guo, X., Ferguson, D. O., and Chang, S. (2009a). Multiple roles for MRE11 at uncapped telomeres. Nature 460, 914-918.
-
(2009)
Nature
, vol.460
, pp. 914-918
-
-
Deng, Y.1
Guo, X.2
Ferguson, D.O.3
Chang, S.4
-
53
-
-
68949198783
-
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres
-
Deng, Z., Norseen, J., Wiedmer, A., Riethman, H., and Lieberman, P. M. (2009b). TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol. Cell 35, 403-413.
-
(2009)
Mol. Cell
, vol.35
, pp. 403-413
-
-
Deng, Z.1
Norseen, J.2
Wiedmer, A.3
Riethman, H.4
Lieberman, P.M.5
-
54
-
-
36049047643
-
The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation
-
Deng, Z., Dheekollu, J., Broccoli, D., Dutta, A., and Lieberman, P. M. (2007). The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation. Curr. Biol. 17, 1989-1995.
-
(2007)
Curr. Biol.
, vol.17
, pp. 1989-1995
-
-
Deng, Z.1
Dheekollu, J.2
Broccoli, D.3
Dutta, A.4
Lieberman, P.M.5
-
55
-
-
0033806120
-
Inactivation of 14-3-3sigma influences telomere behavior and ionizing radiation-induced chromosomal instability
-
Dhar, S., Squire, J. A., Hande, M. P., Wellinger, R. J., and Pandita, T. K. (2000). Inactivation of 14-3-3sigma influences telomere behavior and ionizing radiation-induced chromosomal instability. Mol. Cell. Biol. 20, 7764-7772.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7764-7772
-
-
Dhar, S.1
Squire, J.A.2
Hande, M.P.3
Wellinger, R.J.4
Pandita, T.K.5
-
56
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
Dimitrova, N., Chen, Y. C., Spector, D. L., and De Lange, T. (2008). 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 456, 524-528.
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
Chen, Y.C.2
Spector, D.L.3
De Lange, T.4
-
57
-
-
79953324961
-
Shelterin complex and associated factors at human telomeres
-
Diotti, R., and Loayza, D. (2011). Shelterin complex and associated factors at human telomeres. Nucleus 2, 119-135.
-
(2011)
Nucleus
, vol.2
, pp. 119-135
-
-
Diotti, R.1
Loayza, D.2
-
58
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil, C., Mailand, N., Bekker-Jensen, S., Menard, P., Larsen, D. H., Pepperkok, R., et al. (2009). RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136, 435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
-
59
-
-
79953322962
-
Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs
-
Dregalla, R. C., Zhou, J., Idate, R. R., Battaglia, C. L., Liber, H. L., and Bailey, S. M. (2010). Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs. Aging (Albany NY) 2, 691-708.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 691-708
-
-
Dregalla, R.C.1
Zhou, J.2
Idate, R.R.3
Battaglia, C.L.4
Liber, H.L.5
Bailey, S.M.6
-
60
-
-
1842424729
-
Resolution of sister telomere association is required for progression through mitosis
-
Dynek, J. N., and Smith, S. (2004). Resolution of sister telomere association is required for progression through mitosis. Science 304, 97-100.
-
(2004)
Science
, vol.304
, pp. 97-100
-
-
Dynek, J.N.1
Smith, S.2
-
61
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst, J., Kheradpour, P., Mikkelsen, T. S., Shoresh, N., Ward, L. D., Epstein, C. B., et al. (2011). Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49.
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
Ward, L.D.5
Epstein, C.B.6
-
62
-
-
0029007358
-
Organization of telomeric and subtelomeric chromatin in the higher plant Nicotiana tabacum
-
Fajkus, J., Kovarik, A., Kralovics, R., and Bezdek, M. (1995). Organization of telomeric and subtelomeric chromatin in the higher plant Nicotiana tabacum. Mol. Gen. Genet. 247, 633-638.
-
(1995)
Mol. Gen. Genet.
, vol.247
, pp. 633-638
-
-
Fajkus, J.1
Kovarik, A.2
Kralovics, R.3
Bezdek, M.4
-
64
-
-
0032215539
-
The heterochromatin protein 1 prevents telomere fusions in Drosophila
-
Fanti, L., Giovinazzo, G., Berloco, M., and Pimpinelli, S. (1998). The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol. Cell 2, 527-538.
-
(1998)
Mol. Cell
, vol.2
, pp. 527-538
-
-
Fanti, L.1
Giovinazzo, G.2
Berloco, M.3
Pimpinelli, S.4
-
65
-
-
84860491777
-
Telomerase efficiently elongates highly transcribing telomeres in human cancer cells
-
doi:10.1371/journal.pone.0035714
-
Farnung, B. O., Brun, C. M., Arora, R., Lorenzi, L. E., and Azzalin, C. M. (2012). Telomerase efficiently elongates highly transcribing telomeres in human cancer cells. PLoS ONE 7:e35714. doi:10.1371/journal.pone.0035714
-
(2012)
PLoS ONE
, vol.7
-
-
Farnung, B.O.1
Brun, C.M.2
Arora, R.3
Lorenzi, L.E.4
Azzalin, C.M.5
-
66
-
-
79960004074
-
The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast
-
Ferreira, H. C., Luke, B., Schober, H., Kalck, V., Lingner, J., and Gasser, S. M. (2011). The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nat. Cell Biol. 13, 867-874.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 867-874
-
-
Ferreira, H.C.1
Luke, B.2
Schober, H.3
Kalck, V.4
Lingner, J.5
Gasser, S.M.6
-
67
-
-
0033988692
-
The main role of the sequence-dependent DNA elasticity in determining the free energy of nucleosome formation on telomeric DNAs
-
Filesi, I., Cacchione, S., De Santis, P., Rossetti, L., and Savino, M. (2000). The main role of the sequence-dependent DNA elasticity in determining the free energy of nucleosome formation on telomeric DNAs. Biophys. Chem. 83, 223-237.
-
(2000)
Biophys. Chem.
, vol.83
, pp. 223-237
-
-
Filesi, I.1
Cacchione, S.2
De Santis, P.3
Rossetti, L.4
Savino, M.5
-
68
-
-
79953033701
-
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA
-
Flynn, R. L., Centore, R. C., O'Sullivan, R. J., Rai, R., Tse, A., Songyang, Z., et al. (2011). TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature 471, 532-536.
-
(2011)
Nature
, vol.471
, pp. 532-536
-
-
Flynn, R.L.1
Centore, R.C.2
O'Sullivan, R.J.3
Rai, R.4
Tse, A.5
Songyang, Z.6
-
69
-
-
33744964250
-
hSnm1B is a novel telomere-associated protein
-
Freibaum, B. D., and Counter, C. M. (2006). hSnm1B is a novel telomere-associated protein. J. Biol. Chem. 281, 15033-15036.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15033-15036
-
-
Freibaum, B.D.1
Counter, C.M.2
-
70
-
-
78649819167
-
Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence
-
Fujita, K., Horikawa, I., Mondal, A. M., Jenkins, L. M., Appella, E., Vojtesek, B., et al. (2010). Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence. Nat. Cell Biol. 12, 1205-1212.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1205-1212
-
-
Fujita, K.1
Horikawa, I.2
Mondal, A.M.3
Jenkins, L.M.4
Appella, E.5
Vojtesek, B.6
-
71
-
-
84859372986
-
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
-
Fumagalli, M., Rossiello, F., Clerici, M., Barozzi, S., Cittaro, D., Kaplunov, J. M., et al. (2012). Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat. Cell Biol. 14, 355-365.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 355-365
-
-
Fumagalli, M.1
Rossiello, F.2
Clerici, M.3
Barozzi, S.4
Cittaro, D.5
Kaplunov, J.M.6
-
72
-
-
84860010923
-
TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner
-
doi:10.1371/journal.pone.0034386
-
Galati, A., Magdinier, F., Colasanti, V., Bauwens, S., Pinte, S., Ricordy, R., et al. (2012). TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner. PLoS ONE 7:e34386. doi:10.1371/journal.pone.0034386
-
(2012)
PLoS ONE
, vol.7
-
-
Galati, A.1
Magdinier, F.2
Colasanti, V.3
Bauwens, S.4
Pinte, S.5
Ricordy, R.6
-
73
-
-
33745226438
-
The human telomeric protein TRF1 specifically recognizes nucleosomal binding sites and alters nucleosome structure
-
Galati, A., Rossetti, L., Pisano, S., Chapman, L., Rhodes, D., Savino, M., et al. (2006). The human telomeric protein TRF1 specifically recognizes nucleosomal binding sites and alters nucleosome structure. J. Mol. Biol. 360, 377-385.
-
(2006)
J. Mol. Biol.
, vol.360
, pp. 377-385
-
-
Galati, A.1
Rossetti, L.2
Pisano, S.3
Chapman, L.4
Rhodes, D.5
Savino, M.6
-
74
-
-
0036843088
-
A role for the Rb family of proteins in controlling telomere length
-
Garcia-Cao, M., Gonzalo, S., Dean, D., and Blasco, M. A. (2002). A role for the Rb family of proteins in controlling telomere length. Nat. Genet. 32, 415-419.
-
(2002)
Nat. Genet.
, vol.32
, pp. 415-419
-
-
Garcia-Cao, M.1
Gonzalo, S.2
Dean, D.3
Blasco, M.A.4
-
75
-
-
0347988045
-
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
-
Garcia-Cao, M., O'Sullivan, R., Peters, A. H., Jenuwein, T., and Blasco, M. A. (2004). Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat. Genet. 36, 94-99.
-
(2004)
Nat. Genet.
, vol.36
, pp. 94-99
-
-
Garcia-Cao, M.1
O'Sullivan, R.2
Peters, A.H.3
Jenuwein, T.4
Blasco, M.A.5
-
76
-
-
0035909929
-
DNA-PKcs is critical for telomere capping
-
Gilley, D., Tanaka, H., Hande, M. P., Kurimasa, A., Li, G. C., Oshimura, M., et al. (2001). DNA-PKcs is critical for telomere capping. Proc. Natl. Acad. Sci. U.S.A. 98, 15084-15088.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 15084-15088
-
-
Gilley, D.1
Tanaka, H.2
Hande, M.P.3
Kurimasa, A.4
Li, G.C.5
Oshimura, M.6
-
77
-
-
0027298713
-
Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites
-
Gilson, E., Roberge, M., Giraldo, R., Rhodes, D., and Gasser, S. M. (1993). Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. J. Mol. Biol. 231, 293-310.
-
(1993)
J. Mol. Biol.
, vol.231
, pp. 293-310
-
-
Gilson, E.1
Roberge, M.2
Giraldo, R.3
Rhodes, D.4
Gasser, S.M.5
-
78
-
-
77649099092
-
Distinct factors control histone variant H3.3 localization at specific genomic regions
-
Goldberg, A. D., Banaszynski, L. A., Noh, K. M., Lewis, P. W., Elsaesser, S. J., Stadler, S., et al. (2010). Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 140, 678-691.
-
(2010)
Cell
, vol.140
, pp. 678-691
-
-
Goldberg, A.D.1
Banaszynski, L.A.2
Noh, K.M.3
Lewis, P.W.4
Elsaesser, S.J.5
Stadler, S.6
-
79
-
-
25144491542
-
Role of Rb family in the epigenetic definition of chromatin
-
Gonzalo, S., and Blasco, M. A. (2005). Role of Rb family in the epigenetic definition of chromatin. Cell Cycle 4, 752-755.
-
(2005)
Cell Cycle
, vol.4
, pp. 752-755
-
-
Gonzalo, S.1
Blasco, M.A.2
-
80
-
-
20244376464
-
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
-
Gonzalo, S., Garcia-Cao, M., Fraga, M. F., Schotta, G., Peters, A. H., Cotter, S. E., et al. (2005). Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat. Cell Biol. 7, 420-428.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
Garcia-Cao, M.2
Fraga, M.F.3
Schotta, G.4
Peters, A.H.5
Cotter, S.E.6
-
81
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
Gonzalo, S., Jaco, I., Fraga, M. F., Chen, T., Li, E., Esteller, M., et al. (2006). DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat. Cell Biol. 8, 416-424.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
-
82
-
-
0025201982
-
Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription
-
Gottschling, D. E., Aparicio, O. M., Billington, B. L., and Zakian, V. A. (1990). Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63, 751-762.
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
Aparicio, O.M.2
Billington, B.L.3
Zakian, V.A.4
-
83
-
-
84860210469
-
Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast
-
Greenwood, J., and Cooper, J. P. (2012). Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast. Nucleic Acids Res. 40, 2956-2963.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2956-2963
-
-
Greenwood, J.1
Cooper, J.P.2
-
84
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith, J. D., Comeau, L., Rosenfield, S., Stansel, R. M., Bianchi, A., Moss, H., et al. (1999). Mammalian telomeres end in a large duplex loop. Cell 97, 503-514.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
Stansel, R.M.4
Bianchi, A.5
Moss, H.6
-
85
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
86
-
-
79961029209
-
SUMOylation regulates telomere length homeostasis by targeting Cdc13
-
Hang, L. E., Liu, X., Cheung, I., Yang, Y., and Zhao, X. (2011). SUMOylation regulates telomere length homeostasis by targeting Cdc13. Nat. Struct. Mol. Biol. 18, 920-926.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 920-926
-
-
Hang, L.E.1
Liu, X.2
Cheung, I.3
Yang, Y.4
Zhao, X.5
-
87
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley, C. B., Futcher, A. B., and Greider, C. W. (1990). Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
88
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
Heaphy, C. M., De Wilde, R. F., Jiao, Y., Klein, A. P., Edil, B. H., Shi, C., et al. (2011). Altered telomeres in tumors with ATRX and DAXX mutations. Science 333, 425.
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
De Wilde, R.F.2
Jiao, Y.3
Klein, A.P.4
Edil, B.H.5
Shi, C.6
-
89
-
-
84871933264
-
Consequences of telomere shortening during lifespan
-
Henriques, C. M., and Ferreira, M. G. (2012). Consequences of telomere shortening during lifespan. Curr. Opin. Cell Biol. 24, 804-808.
-
(2012)
Curr. Opin. Cell Biol.
, vol.24
, pp. 804-808
-
-
Henriques, C.M.1
Ferreira, M.G.2
-
90
-
-
67649763465
-
Ubiquitin ligase RLIM Modulates telomere length homeostasis through a proteolysis of TRF1
-
Her, Y. R., and Chung, I. K. (2009). Ubiquitin ligase RLIM Modulates telomere length homeostasis through a proteolysis of TRF1. J. Biol. Chem. 284, 8557-8566.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8557-8566
-
-
Her, Y.R.1
Chung, I.K.2
-
91
-
-
2442511752
-
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
-
Herbig, U., Jobling, W. A., Chen, B. P., Chen, D. J., and Sedivy, J. M. (2004). Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 14, 501-513.
-
(2004)
Mol. Cell
, vol.14
, pp. 501-513
-
-
Herbig, U.1
Jobling, W.A.2
Chen, B.P.3
Chen, D.J.4
Sedivy, J.M.5
-
92
-
-
84859352385
-
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
-
Hewitt, G., Jurk, D., Marques, F. D., Correia-Melo, C., Hardy, T., Gackowska, A., et al. (2012). Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Nat. Commun. 3, 708.
-
(2012)
Nat. Commun.
, vol.3
, pp. 708
-
-
Hewitt, G.1
Jurk, D.2
Marques, F.D.3
Correia-Melo, C.4
Hardy, T.5
Gackowska, A.6
-
93
-
-
0034669104
-
Ku acts in a unique way at the mammalian telomere to prevent end joining
-
Hsu, H. L., Gilley, D., Galande, S. A., Hande, M. P., Allen, B., Kim, S. H., et al. (2000). Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev. 14, 2807-2812.
-
(2000)
Genes Dev.
, vol.14
, pp. 2807-2812
-
-
Hsu, H.L.1
Gilley, D.2
Galande, S.A.3
Hande, M.P.4
Allen, B.5
Kim, S.H.6
-
94
-
-
77951498531
-
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome
-
Iacovoni, J. S., Caron, P., Lassadi, I., Nicolas, E., Massip, L., Trouche, D., et al. (2010). High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. EMBO J. 29, 1446-1457.
-
(2010)
EMBO J.
, vol.29
, pp. 1446-1457
-
-
Iacovoni, J.S.1
Caron, P.2
Lassadi, I.3
Nicolas, E.4
Massip, L.5
Trouche, D.6
-
95
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai, S., Armstrong, C. M., Kaeberlein, M., and Guarente, L. (2000). Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403, 795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
96
-
-
1842789989
-
Mechanisms of cellular senescence in human and mouse cells
-
Itahana, K., Campisi, J., and Dimri, G. P. (2004). Mechanisms of cellular senescence in human and mouse cells. Biogerontology 5, 1-10.
-
(2004)
Biogerontology
, vol.5
, pp. 1-10
-
-
Itahana, K.1
Campisi, J.2
Dimri, G.P.3
-
97
-
-
84859530323
-
Fusing telomeres with RNF8
-
Jacobs, J. J. (2012). Fusing telomeres with RNF8. Nucleus 3, 143-149.
-
(2012)
Nucleus
, vol.3
, pp. 143-149
-
-
Jacobs, J.J.1
-
98
-
-
77956525242
-
HAATI survivors replace canonical telomeres with blocks of generic heterochromatin
-
Jain, D., Hebden, A. K., Nakamura, T. M., Miller, K. M., and Cooper, J. P. (2010). HAATI survivors replace canonical telomeres with blocks of generic heterochromatin. Nature 467, 223-227.
-
(2010)
Nature
, vol.467
, pp. 223-227
-
-
Jain, D.1
Hebden, A.K.2
Nakamura, T.M.3
Miller, K.M.4
Cooper, J.P.5
-
99
-
-
79952279828
-
DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors
-
Jiao, Y., Shi, C., Edil, B. H., De Wilde, R. F., Klimstra, D. S., Maitra, A., et al. (2011). DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science 331, 1199-1203.
-
(2011)
Science
, vol.331
, pp. 1199-1203
-
-
Jiao, Y.1
Shi, C.2
Edil, B.H.3
De Wilde, R.F.4
Klimstra, D.S.5
Maitra, A.6
-
100
-
-
52949107241
-
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure
-
doi:10.1371/journal.pgen.1000190
-
Jones, B., Su, H., Bhat, A., Lei, H., Bajko, J., Hevi, S., et al. (2008). The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet. 4:e1000190. doi:10.1371/journal.pgen.1000190
-
(2008)
PLoS Genet.
, vol.4
-
-
Jones, B.1
Su, H.2
Bhat, A.3
Lei, H.4
Bajko, J.5
Hevi, S.6
-
101
-
-
19344374569
-
The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response
-
doi:10.1371/journal.pbio.0020240
-
Karlseder, J., Hoke, K., Mirzoeva, O. K., Bakkenist, C., Kastan, M. B., Petrini, J. H., et al. (2004). The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. PLoS Biol. 2:E240. doi:10.1371/journal.pbio.0020240
-
(2004)
PLoS Biol.
, vol.2
-
-
Karlseder, J.1
Hoke, K.2
Mirzoeva, O.K.3
Bakkenist, C.4
Kastan, M.B.5
Petrini, J.H.6
-
102
-
-
84555178942
-
Five dysfunctional telomeres predict onset of senescence in human cells
-
Kaul, Z., Cesare, A. J., Huschtscha, L. I., Neumann, A. A., and Reddel, R. R. (2012). Five dysfunctional telomeres predict onset of senescence in human cells. EMBO Rep. 13, 52-59.
-
(2012)
EMBO Rep.
, vol.13
, pp. 52-59
-
-
Kaul, Z.1
Cesare, A.J.2
Huschtscha, L.I.3
Neumann, A.A.4
Reddel, R.R.5
-
103
-
-
84864770143
-
Chromosome end protection by blunt-ended telomeres
-
Kazda, A., Zellinger, B., Rossler, M., Derboven, E., Kusenda, B., and Riha, K. (2012). Chromosome end protection by blunt-ended telomeres. Genes Dev. 26, 1703-1713.
-
(2012)
Genes Dev.
, vol.26
, pp. 1703-1713
-
-
Kazda, A.1
Zellinger, B.2
Rossler, M.3
Derboven, E.4
Kusenda, B.5
Riha, K.6
-
104
-
-
0034193635
-
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase
-
Kharbanda, S., Kumar, V., Dhar, S., Pandey, P., Chen, C., Majumder, P., et al. (2000). Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase. Curr. Biol. 10, 568-575.
-
(2000)
Curr. Biol.
, vol.10
, pp. 568-575
-
-
Kharbanda, S.1
Kumar, V.2
Dhar, S.3
Pandey, P.4
Chen, C.5
Majumder, P.6
-
105
-
-
64049099444
-
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
-
Kim, H., Lee, O. H., Xin, H., Chen, L. Y., Qin, J., Chae, H. K., et al. (2009). TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs. Nat. Struct. Mol. Biol. 16, 372-379.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 372-379
-
-
Kim, H.1
Lee, O.H.2
Xin, H.3
Chen, L.Y.4
Qin, J.5
Chae, H.K.6
-
106
-
-
17044367499
-
Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT
-
Kim, J. H., Park, S. M., Kang, M. R., Oh, S. Y., Lee, T. H., Muller, M. T., et al. (2005). Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev. 19, 776-781.
-
(2005)
Genes Dev.
, vol.19
, pp. 776-781
-
-
Kim, J.H.1
Park, S.M.2
Kang, M.R.3
Oh, S.Y.4
Lee, T.H.5
Muller, M.T.6
-
107
-
-
46649111985
-
Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation
-
Kim, M. K., Kang, M. R., Nam, H. W., Bae, Y. S., Kim, Y. S., and Chung, I. K. (2008). Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation. J. Biol. Chem. 283, 14144-14152.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14144-14152
-
-
Kim, M.K.1
Kang, M.R.2
Nam, H.W.3
Bae, Y.S.4
Kim, Y.S.5
Chung, I.K.6
-
108
-
-
0036867444
-
Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
-
Koering, C. E., Pollice, A., Zibella, M. P., Bauwens, S., Puisieux, A., Brunori, M., et al. (2002). Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity. EMBO Rep. 3, 1055-1061.
-
(2002)
EMBO Rep.
, vol.3
, pp. 1055-1061
-
-
Koering, C.E.1
Pollice, A.2
Zibella, M.P.3
Bauwens, S.4
Puisieux, A.5
Brunori, M.6
-
109
-
-
77955914627
-
Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
-
Kusumoto-Matsuo, R., Opresko, P. L., Ramsden, D., Tahara, H., and Bohr, V. A. (2010). Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops. Aging (Albany NY) 2, 274-284.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 274-284
-
-
Kusumoto-Matsuo, R.1
Opresko, P.L.2
Ramsden, D.3
Tahara, H.4
Bohr, V.A.5
-
110
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. (2001). Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410, 116-120.
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
111
-
-
77954958459
-
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair
-
Lam, Y. C., Akhter, S., Gu, P., Ye, J., Poulet, A., Giraud-Panis, M. J., et al. (2010). SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. EMBO J. 29, 2230-2241.
-
(2010)
EMBO J.
, vol.29
, pp. 2230-2241
-
-
Lam, Y.C.1
Akhter, S.2
Gu, P.3
Ye, J.4
Poulet, A.5
Giraud-Panis, M.J.6
-
112
-
-
78049342712
-
The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response
-
Landsverk, H. B., Mora-Bermudez, F., Landsverk, O. J., Hasvold, G., Naderi, S., Bakke, O., et al. (2010). The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response. EMBO Rep. 11, 868-875.
-
(2010)
EMBO Rep.
, vol.11
, pp. 868-875
-
-
Landsverk, H.B.1
Mora-Bermudez, F.2
Landsverk, O.J.3
Hasvold, G.4
Naderi, S.5
Bakke, O.6
-
113
-
-
77958494782
-
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner
-
Law, M. J., Lower, K. M., Voon, H. P., Hughes, J. R., Garrick, D., Viprakasit, V., et al. (2010). ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell 143, 367-378.
-
(2010)
Cell
, vol.143
, pp. 367-378
-
-
Law, M.J.1
Lower, K.M.2
Voon, H.P.3
Hughes, J.R.4
Garrick, D.5
Viprakasit, V.6
-
114
-
-
0027465862
-
A positive role for histone acetylation in transcription factor access to nucleosomal DNA
-
Lee, D. Y., Hayes, J. J., Pruss, D., and Wolffe, A. P. (1993). A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72, 73-84.
-
(1993)
Cell
, vol.72
, pp. 73-84
-
-
Lee, D.Y.1
Hayes, J.J.2
Pruss, D.3
Wolffe, A.P.4
-
115
-
-
78650632231
-
CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity
-
Lee, J. H., Khadka, P., Baek, S. H., and Chung, I. K. (2010). CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity. J. Biol. Chem. 285, 42033-42045.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 42033-42045
-
-
Lee, J.H.1
Khadka, P.2
Baek, S.H.3
Chung, I.K.4
-
116
-
-
33644855565
-
The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance
-
Lee, T. H., Perrem, K., Harper, J. W., Lu, K. P., and Zhou, X. Z. (2006). The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance. J. Biol. Chem. 281, 759-768.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 759-768
-
-
Lee, T.H.1
Perrem, K.2
Harper, J.W.3
Lu, K.P.4
Zhou, X.Z.5
-
117
-
-
58149351370
-
Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance
-
Lee, T. H., Tun-Kyi, A., Shi, R., Lim, J., Soohoo, C., Finn, G., et al. (2009). Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance. Nat. Cell Biol. 11, 97-105.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 97-105
-
-
Lee, T.H.1
Tun-Kyi, A.2
Shi, R.3
Lim, J.4
Soohoo, C.5
Finn, G.6
-
118
-
-
0028928198
-
Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes
-
Lejnine, S., Makarov, V. L., and Langmore, J. P. (1995). Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes. Proc. Natl. Acad. Sci. U.S.A. 92, 2393-2397.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 2393-2397
-
-
Lejnine, S.1
Makarov, V.L.2
Langmore, J.P.3
-
119
-
-
33745651993
-
The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair
-
Lenain, C., Bauwens, S., Amiard, S., Brunori, M., Giraud-Panis, M. J., and Gilson, E. (2006). The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair. Curr. Biol. 16, 1303-1310.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1303-1310
-
-
Lenain, C.1
Bauwens, S.2
Amiard, S.3
Brunori, M.4
Giraud-Panis, M.J.5
Gilson, E.6
-
120
-
-
77956282773
-
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
-
Lewis, P. W., Elsaesser, S. J., Noh, K. M., Stadler, S. C., and Allis, C. D. (2010). Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc. Natl. Acad. Sci. U.S.A. 107, 14075-14080.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 14075-14080
-
-
Lewis, P.W.1
Elsaesser, S.J.2
Noh, K.M.3
Stadler, S.C.4
Allis, C.D.5
-
121
-
-
40349094707
-
WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening
-
Li, B., Jog, S. P., Reddy, S., and Comai, L. (2008). WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening. Mol. Cell. Biol. 28, 1892-1904.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 1892-1904
-
-
Li, B.1
Jog, S.P.2
Reddy, S.3
Comai, L.4
-
122
-
-
38649118195
-
Endings in the middle: current knowledge of interstitial telomeric sequences
-
Lin, K. W., and Yan, J. (2008). Endings in the middle: current knowledge of interstitial telomeric sequences. Mutat. Res. 658, 95-110.
-
(2008)
Mutat. Res.
, vol.658
, pp. 95-110
-
-
Lin, K.W.1
Yan, J.2
-
123
-
-
77954277522
-
Multiple roles of BRIT1/MCPH1 in DNA damage response, DNA repair, and cancer suppression
-
Lin, S. Y., Liang, Y., and Li, K. (2010). Multiple roles of BRIT1/MCPH1 in DNA damage response, DNA repair, and cancer suppression. Yonsei Med. J. 51, 295-301.
-
(2010)
Yonsei Med. J.
, vol.51
, pp. 295-301
-
-
Lin, S.Y.1
Liang, Y.2
Li, K.3
-
124
-
-
68549136741
-
G-quadruplex structures: in vivo evidence and function
-
Lipps, H. J., and Rhodes, D. (2009). G-quadruplex structures: in vivo evidence and function. Trends Cell Biol. 19, 414-422.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 414-422
-
-
Lipps, H.J.1
Rhodes, D.2
-
125
-
-
84864619205
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
-
doi:10.1371/journal.pgen.1002772
-
Lovejoy, C. A., Li, W., Reisenweber, S., Thongthip, S., Bruno, J., De Lange, T., et al. (2012). Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet. 8:e1002772. doi:10.1371/journal.pgen.1002772
-
(2012)
PLoS Genet.
, vol.8
-
-
Lovejoy, C.A.1
Li, W.2
Reisenweber, S.3
Thongthip, S.4
Bruno, J.5
De Lange, T.6
-
126
-
-
33644625997
-
Dynamic nucleosomes
-
Luger, K. (2006). Dynamic nucleosomes. Chromosome Res. 14, 5-16.
-
(2006)
Chromosome Res.
, vol.14
, pp. 5-16
-
-
Luger, K.1
-
127
-
-
84863461725
-
Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence
-
Maicher, A., Kastner, L., Dees, M., and Luke, B. (2012). Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence. Nucleic Acids Res. 40, 6649-6659.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 6649-6659
-
-
Maicher, A.1
Kastner, L.2
Dees, M.3
Luke, B.4
-
128
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand, N., Bekker-Jensen, S., Faustrup, H., Melander, F., Bartek, J., Lukas, C., et al. (2007). RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131, 887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
-
129
-
-
80054047834
-
Hypomethylating drugs efficiently decrease cytosine methylation in telomeric DNA and activate telomerase without affecting telomere lengths in tobacco cells
-
Majerova, E., Fojtova, M., Mozgova, I., Bittova, M., and Fajkus, J. (2011). Hypomethylating drugs efficiently decrease cytosine methylation in telomeric DNA and activate telomerase without affecting telomere lengths in tobacco cells. Plant Mol. Biol. 77, 371-380.
-
(2011)
Plant Mol. Biol.
, vol.77
, pp. 371-380
-
-
Majerova, E.1
Fojtova, M.2
Mozgova, I.3
Bittova, M.4
Fajkus, J.5
-
130
-
-
0031000884
-
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
-
Makarov, V. L., Hirose, Y., and Langmore, J. P. (1997). Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 88, 657-666.
-
(1997)
Cell
, vol.88
, pp. 657-666
-
-
Makarov, V.L.1
Hirose, Y.2
Langmore, J.P.3
-
131
-
-
0027212790
-
Nucleosomal organization of telomere-specific chromatin in rat
-
Makarov, V. L., Lejnine, S., Bedoyan, J., and Langmore, J. P. (1993). Nucleosomal organization of telomere-specific chromatin in rat. Cell 73, 775-787.
-
(1993)
Cell
, vol.73
, pp. 775-787
-
-
Makarov, V.L.1
Lejnine, S.2
Bedoyan, J.3
Langmore, J.P.4
-
132
-
-
38049080704
-
Drosophila telomeres: an exception providing new insights
-
Mason, J. M., Frydrychova, R. C., and Biessmann, H. (2008). Drosophila telomeres: an exception providing new insights. Bioessays 30, 25-37.
-
(2008)
Bioessays
, vol.30
, pp. 25-37
-
-
Mason, J.M.1
Frydrychova, R.C.2
Biessmann, H.3
-
133
-
-
84860345945
-
ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance
-
McKerlie, M., Lin, S., and Zhu, X. D. (2012). ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance. Nucleic Acids Res. 40, 3975-3989.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 3975-3989
-
-
McKerlie, M.1
Lin, S.2
Zhu, X.D.3
-
134
-
-
84880307126
-
Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres
-
McKerlie, M., and Zhu, X. D. (2011). Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres. Nat. Commun. 2, 371.
-
(2011)
Nat. Commun.
, vol.2
, pp. 371
-
-
McKerlie, M.1
Zhu, X.D.2
-
135
-
-
2442463402
-
Organization of telomeric nucleosomes: atomic force microscopy imaging and theoretical modeling
-
Mechelli, R., Anselmi, C., Cacchione, S., De Santis, P., and Savino, M. (2004). Organization of telomeric nucleosomes: atomic force microscopy imaging and theoretical modeling. FEBS Lett. 566, 131-135.
-
(2004)
FEBS Lett.
, vol.566
, pp. 131-135
-
-
Mechelli, R.1
Anselmi, C.2
Cacchione, S.3
De Santis, P.4
Savino, M.5
-
136
-
-
0025329846
-
Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes
-
Meyne, J., Baker, R. J., Hobart, H. H., Hsu, T. C., Ryder, O. A., Ward, O. G., et al. (1990). Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes. Chromosoma 99, 3-10.
-
(1990)
Chromosoma
, vol.99
, pp. 3-10
-
-
Meyne, J.1
Baker, R.J.2
Hobart, H.H.3
Hsu, T.C.4
Ryder, O.A.5
Ward, O.G.6
-
137
-
-
77949884776
-
Water soluble cationic perylene derivatives as possible telomerase inhibitors: the search for selective G-quadruplex targeting
-
Micheli, E., D'Ambrosio, D., Franceschin, M., and Savino, M. (2009). Water soluble cationic perylene derivatives as possible telomerase inhibitors: the search for selective G-quadruplex targeting. Mini Rev. Med. Chem. 9, 1622-1632.
-
(2009)
Mini Rev. Med. Chem.
, vol.9
, pp. 1622-1632
-
-
Micheli, E.1
D'Ambrosio, D.2
Franceschin, M.3
Savino, M.4
-
138
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
Michishita, E., McCord, R. A., Berber, E., Kioi, M., Padilla-Nash, H., Damian, M., et al. (2008). SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452, 492-496.
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
-
139
-
-
69249221533
-
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
-
Michishita, E., McCord, R. A., Boxer, L. D., Barber, M. F., Hong, T., Gozani, O., et al. (2009). Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle 8, 2664-2666.
-
(2009)
Cell Cycle
, vol.8
, pp. 2664-2666
-
-
Michishita, E.1
McCord, R.A.2
Boxer, L.D.3
Barber, M.F.4
Hong, T.5
Gozani, O.6
-
140
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen, T. S., Ku, M., Jaffe, D. B., Issac, B., Lieberman, E., Giannoukos, G., et al. (2007). Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, 553-560.
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
-
141
-
-
84859371639
-
Histone marks: repairing DNA breaks within the context of chromatin
-
Miller, K. M., and Jackson, S. P. (2012). Histone marks: repairing DNA breaks within the context of chromatin. Biochem. Soc. Trans. 40, 370-376.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 370-376
-
-
Miller, K.M.1
Jackson, S.P.2
-
142
-
-
77951223672
-
Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing
-
Mimura, S., Yamaguchi, T., Ishii, S., Noro, E., Katsura, T., Obuse, C., et al. (2010). Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing. J. Biol. Chem. 285, 9858-9867.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9858-9867
-
-
Mimura, S.1
Yamaguchi, T.2
Ishii, S.3
Noro, E.4
Katsura, T.5
Obuse, C.6
-
143
-
-
59649084380
-
Telomeres, histone code, and DNA damage response
-
Misri, S., Pandita, S., Kumar, R., and Pandita, T. K. (2008). Telomeres, histone code, and DNA damage response. Cytogenet. Genome Res. 122, 297-307.
-
(2008)
Cytogenet. Genome Res.
, vol.122
, pp. 297-307
-
-
Misri, S.1
Pandita, S.2
Kumar, R.3
Pandita, T.K.4
-
144
-
-
70249132548
-
Arginine methylation regulates telomere length and stability
-
Mitchell, T. R., Glenfield, K., Jeyanthan, K., and Zhu, X. D. (2009). Arginine methylation regulates telomere length and stability. Mol. Cell. Biol. 29, 4918-4934.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4918-4934
-
-
Mitchell, T.R.1
Glenfield, K.2
Jeyanthan, K.3
Zhu, X.D.4
-
145
-
-
45549090631
-
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length
-
Miyoshi, T., Kanoh, J., Saito, M., and Ishikawa, F. (2008). Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science 320, 1341-1344.
-
(2008)
Science
, vol.320
, pp. 1341-1344
-
-
Miyoshi, T.1
Kanoh, J.2
Saito, M.3
Ishikawa, F.4
-
146
-
-
70349690459
-
Protection and replication of telomeres in fission yeast
-
Moser, B. A., and Nakamura, T. M. (2009). Protection and replication of telomeres in fission yeast. Biochem. Cell Biol. 87, 747-758.
-
(2009)
Biochem. Cell Biol.
, vol.87
, pp. 747-758
-
-
Moser, B.A.1
Nakamura, T.M.2
-
147
-
-
78649511027
-
Small-molecule-mediated G-quadruplex isolation from human cells
-
Muller, S., Kumari, S., Rodriguez, R., and Balasubramanian, S. (2010). Small-molecule-mediated G-quadruplex isolation from human cells. Nat. Chem. 2, 1095-1098.
-
(2010)
Nat. Chem.
, vol.2
, pp. 1095-1098
-
-
Muller, S.1
Kumari, S.2
Rodriguez, R.3
Balasubramanian, S.4
-
148
-
-
27144515686
-
XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer
-
Munoz, P., Blanco, R., Flores, J. M., and Blasco, M. A. (2005). XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. Nat. Genet. 37, 1063-1071.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1063-1071
-
-
Munoz, P.1
Blanco, R.2
Flores, J.M.3
Blasco, M.A.4
-
149
-
-
73249117060
-
CpG-island promoters drive transcription of human telomeres
-
Nergadze, S. G., Farnung, B. O., Wischnewski, H., Khoriauli, L., Vitelli, V., Chawla, R., et al. (2009). CpG-island promoters drive transcription of human telomeres. RNA 15, 2186-2194.
-
(2009)
RNA
, vol.15
, pp. 2186-2194
-
-
Nergadze, S.G.1
Farnung, B.O.2
Wischnewski, H.3
Khoriauli, L.4
Vitelli, V.5
Chawla, R.6
-
150
-
-
3342974395
-
Closed chromatin loops at the ends of chromosomes
-
Nikitina, T., and Woodcock, C. L. (2004). Closed chromatin loops at the ends of chromosomes. J. Cell Biol. 166, 161-165.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 161-165
-
-
Nikitina, T.1
Woodcock, C.L.2
-
151
-
-
33847372902
-
Physiological relevance of telomeric G-quadruplex formation: a potential drug target
-
Oganesian, L., and Bryan, T. M. (2007). Physiological relevance of telomeric G-quadruplex formation: a potential drug target. Bioessays 29, 155-165.
-
(2007)
Bioessays
, vol.29
, pp. 155-165
-
-
Oganesian, L.1
Bryan, T.M.2
-
152
-
-
79954474478
-
Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance
-
Oganesian, L., and Karlseder, J. (2011). Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance. Mol. Cell 42, 224-236.
-
(2011)
Mol. Cell
, vol.42
, pp. 224-236
-
-
Oganesian, L.1
Karlseder, J.2
-
153
-
-
77954759082
-
Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT
-
Oh, W., Lee, E. W., Lee, D., Yang, M. R., Ko, A., Yoon, C. H., et al. (2010). Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT. Oncogene 29, 4101-4112.
-
(2010)
Oncogene
, vol.29
, pp. 4101-4112
-
-
Oh, W.1
Lee, E.W.2
Lee, D.3
Yang, M.R.4
Ko, A.5
Yoon, C.H.6
-
154
-
-
84874351566
-
A two-step mechanism for TRF2-mediated chromosome-end protection
-
in press.
-
Okamoto, K., Bartocci, C., Ouzounov, I., Diedrich, J. K., Yates, J. R. III, and Denchi, E. L. (2013). A two-step mechanism for TRF2-mediated chromosome-end protection. Nature, in press.
-
(2013)
Nature
-
-
Okamoto, K.1
Bartocci, C.2
Ouzounov, I.3
Diedrich, J.K.4
Yates III, J.R.5
Denchi, E.L.6
-
155
-
-
32244446953
-
Lunasensor, infradian rhythms, telomeres, and the chronomere program of aging
-
Olovnikov, A. (2005). Lunasensor, infradian rhythms, telomeres, and the chronomere program of aging. Ann. N. Y. Acad. Sci. 1057, 112-132.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1057
, pp. 112-132
-
-
Olovnikov, A.1
-
156
-
-
25444533047
-
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
-
Opresko, P. L., Mason, P. A., Podell, E. R., Lei, M., Hickson, I. D., Cech, T. R., et al. (2005). POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. J. Biol. Chem. 280, 32069-32080.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32069-32080
-
-
Opresko, P.L.1
Mason, P.A.2
Podell, E.R.3
Lei, M.4
Hickson, I.D.5
Cech, T.R.6
-
157
-
-
2942637828
-
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
-
Opresko, P. L., Otterlei, M., Graakjaer, J., Bruheim, P., Dawut, L., Kolvraa, S., et al. (2004). The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2. Mol. Cell 14, 763-774.
-
(2004)
Mol. Cell
, vol.14
, pp. 763-774
-
-
Opresko, P.L.1
Otterlei, M.2
Graakjaer, J.3
Bruheim, P.4
Dawut, L.5
Kolvraa, S.6
-
158
-
-
77957814604
-
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
-
O'Sullivan, R. J., Kubicek, S., Schreiber, S. L., and Karlseder, J. (2010). Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat. Struct. Mol. Biol. 17, 1218-1225.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1218-1225
-
-
O'Sullivan, R.J.1
Kubicek, S.2
Schreiber, S.L.3
Karlseder, J.4
-
159
-
-
36749014473
-
Telomeric position effect: from the yeast paradigm to human pathologies?
-
Ottaviani, A., Gilson, E., and Magdinier, F. (2008). Telomeric position effect: from the yeast paradigm to human pathologies? Biochimie 90, 93-107.
-
(2008)
Biochimie
, vol.90
, pp. 93-107
-
-
Ottaviani, A.1
Gilson, E.2
Magdinier, F.3
-
160
-
-
27144451010
-
Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
-
Paeschke, K., Simonsson, T., Postberg, J., Rhodes, D., and Lipps, H. J. (2005). Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo. Nat. Struct. Mol. Biol. 12, 847-854.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 847-854
-
-
Paeschke, K.1
Simonsson, T.2
Postberg, J.3
Rhodes, D.4
Lipps, H.J.5
-
161
-
-
78650747994
-
SIRT1 contributes to telomere maintenance and augments global homologous recombination
-
Palacios, J. A., Herranz, D., De Bonis, M. L., Velasco, S., Serrano, M., and Blasco, M. A. (2010). SIRT1 contributes to telomere maintenance and augments global homologous recombination. J. Cell Biol. 191, 1299-1313.
-
(2010)
J. Cell Biol.
, vol.191
, pp. 1299-1313
-
-
Palacios, J.A.1
Herranz, D.2
De Bonis, M.L.3
Velasco, S.4
Serrano, M.5
Blasco, M.A.6
-
162
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm, W., and de Lange, T. (2008). How shelterin protects mammalian telomeres. Annu. Rev. Genet. 42, 301-334.
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
163
-
-
33644555829
-
Mammalian Rad9 plays a role in telomere stability, S-and G2-phase-specific cell survival, and homologous recombinational repair
-
Pandita, R. K., Sharma, G. G., Laszlo, A., Hopkins, K. M., Davey, S., Chakhparonian, M., et al. (2006). Mammalian Rad9 plays a role in telomere stability, S-and G2-phase-specific cell survival, and homologous recombinational repair. Mol. Cell. Biol. 26, 1850-1864.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1850-1864
-
-
Pandita, R.K.1
Sharma, G.G.2
Laszlo, A.3
Hopkins, K.M.4
Davey, S.5
Chakhparonian, M.6
-
164
-
-
4143116771
-
HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila
-
Perrini, B., Piacentini, L., Fanti, L., Altieri, F., Chichiarelli, S., Berloco, M., et al. (2004). HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila. Mol. Cell 15, 467-476.
-
(2004)
Mol. Cell
, vol.15
, pp. 467-476
-
-
Perrini, B.1
Piacentini, L.2
Fanti, L.3
Altieri, F.4
Chichiarelli, S.5
Berloco, M.6
-
165
-
-
80052491304
-
DNA-damage response and repair activities at uncapped telomeres depend on RNF8
-
Peuscher, M. H., and Jacobs, J. J. (2011). DNA-damage response and repair activities at uncapped telomeres depend on RNF8. Nat. Cell Biol. 13, 1139-1145.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1139-1145
-
-
Peuscher, M.H.1
Jacobs, J.J.2
-
166
-
-
84864041566
-
TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends
-
doi:10.1371/journal.pgen.1002747
-
Pfeiffer, V., and Lingner, J. (2012). TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends. PLoS Genet. 8:e1002747. doi:10.1371/journal.pgen.1002747
-
(2012)
PLoS Genet.
, vol.8
-
-
Pfeiffer, V.1
Lingner, J.2
-
167
-
-
56549089924
-
Telomeric nucleosomes: forgotten players at chromosome ends
-
Pisano, S., Galati, A., and Cacchione, S. (2008). Telomeric nucleosomes: forgotten players at chromosome ends. Cell. Mol. Life Sci. 65, 3553-3563.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 3553-3563
-
-
Pisano, S.1
Galati, A.2
Cacchione, S.3
-
168
-
-
77952318828
-
The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility
-
Pisano, S., Leoni, D., Galati, A., Rhodes, D., Savino, M., and Cacchione, S. (2010). The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility. Nucleic Acids Res. 38, 2247-2255.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 2247-2255
-
-
Pisano, S.1
Leoni, D.2
Galati, A.3
Rhodes, D.4
Savino, M.5
Cacchione, S.6
-
169
-
-
34248633105
-
Telomeric nucleosomes are intrinsically mobile
-
Pisano, S., Marchioni, E., Galati, A., Mechelli, R., Savino, M., and Cacchione, S. (2007). Telomeric nucleosomes are intrinsically mobile. J. Mol. Biol. 369, 1153-1162.
-
(2007)
J. Mol. Biol.
, vol.369
, pp. 1153-1162
-
-
Pisano, S.1
Marchioni, E.2
Galati, A.3
Mechelli, R.4
Savino, M.5
Cacchione, S.6
-
170
-
-
33750160175
-
AFM imaging and theoretical modeling studies of sequence-dependent nucleosome positioning
-
Pisano, S., Pascucci, E., Cacchione, S., De Santis, P., and Savino, M. (2006). AFM imaging and theoretical modeling studies of sequence-dependent nucleosome positioning. Biophys. Chem. 124, 81-89.
-
(2006)
Biophys. Chem.
, vol.124
, pp. 81-89
-
-
Pisano, S.1
Pascucci, E.2
Cacchione, S.3
De Santis, P.4
Savino, M.5
-
171
-
-
34447129654
-
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
-
Potts, P. R., and Yu, H. (2007). The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat. Struct. Mol. Biol. 14, 581-590.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 581-590
-
-
Potts, P.R.1
Yu, H.2
-
172
-
-
62649104650
-
TRF2 promotes, remodels and protects telomeric Holliday junctions
-
Poulet, A., Buisson, R., Faivre-Moskalenko, C., Koelblen, M., Amiard, S., Montel, F., et al. (2009). TRF2 promotes, remodels and protects telomeric Holliday junctions. EMBO J. 28, 641-651.
-
(2009)
EMBO J.
, vol.28
, pp. 641-651
-
-
Poulet, A.1
Buisson, R.2
Faivre-Moskalenko, C.3
Koelblen, M.4
Amiard, S.5
Montel, F.6
-
173
-
-
84859340760
-
The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA
-
Poulet, A., Pisano, S., Faivre-Moskalenko, C., Pei, B., Tauran, Y., Haftek-Terreau, Z., et al. (2012). The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA. Nucleic Acids Res. 40, 2566-2576.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2566-2576
-
-
Poulet, A.1
Pisano, S.2
Faivre-Moskalenko, C.3
Pei, B.4
Tauran, Y.5
Haftek-Terreau, Z.6
-
174
-
-
80054688743
-
Terminin: a protein complex that mediates epigenetic maintenance of Drosophila telomeres
-
Raffa, G. D., Ciapponi, L., Cenci, G., and Gatti, M. (2011). Terminin: a protein complex that mediates epigenetic maintenance of Drosophila telomeres. Nucleus 2, 383-391.
-
(2011)
Nucleus
, vol.2
, pp. 383-391
-
-
Raffa, G.D.1
Ciapponi, L.2
Cenci, G.3
Gatti, M.4
-
175
-
-
77955904676
-
Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex
-
Raffa, G. D., Raimondo, D., Sorino, C., Cugusi, S., Cenci, G., Cacchione, S., et al. (2010). Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex. Genes Dev. 24, 1596-1601.
-
(2010)
Genes Dev.
, vol.24
, pp. 1596-1601
-
-
Raffa, G.D.1
Raimondo, D.2
Sorino, C.3
Cugusi, S.4
Cenci, G.5
Cacchione, S.6
-
176
-
-
82955233817
-
The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection
-
Rai, R., Li, J. M., Zheng, H., Lok, G. T., Deng, Y., Huen, M. S., et al. (2011). The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection. Nat. Struct. Mol. Biol. 18, 1400-1407.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1400-1407
-
-
Rai, R.1
Li, J.M.2
Zheng, H.3
Lok, G.T.4
Deng, Y.5
Huen, M.S.6
-
177
-
-
39749176333
-
C. elegans telomeres contain G-strand and C-strand overhangs that are bound by distinct proteins
-
Raices, M., Verdun, R. E., Compton, S. A., Haggblom, C. I., Griffith, J. D., Dillin, A., et al. (2008). C. elegans telomeres contain G-strand and C-strand overhangs that are bound by distinct proteins. Cell 132, 745-757.
-
(2008)
Cell
, vol.132
, pp. 745-757
-
-
Raices, M.1
Verdun, R.E.2
Compton, S.A.3
Haggblom, C.I.4
Griffith, J.D.5
Dillin, A.6
-
178
-
-
84863258208
-
ATRX-mediated chromatin association of histone variant macroH2A1 regulates alpha-globin expression
-
Ratnakumar, K., Duarte, L. F., Leroy, G., Hasson, D., Smeets, D., Vardabasso, C., et al. (2012). ATRX-mediated chromatin association of histone variant macroH2A1 regulates alpha-globin expression. Genes Dev. 26, 433-438.
-
(2012)
Genes Dev.
, vol.26
, pp. 433-438
-
-
Ratnakumar, K.1
Duarte, L.F.2
Leroy, G.3
Hasson, D.4
Smeets, D.5
Vardabasso, C.6
-
179
-
-
77957243987
-
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
-
Redon, S., Reichenbach, P., and Lingner, J. (2010). The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res. 38, 5797-5806.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5797-5806
-
-
Redon, S.1
Reichenbach, P.2
Lingner, J.3
-
180
-
-
64849110610
-
Determination of enriched histone modifications in non-genic portions of the human genome
-
doi:10.1186/1471-2164-10-143
-
Rosenfeld, J. A., Wang, Z., Schones, D. E., Zhao, K., Desalle, R., and Zhang, M. Q. (2009). Determination of enriched histone modifications in non-genic portions of the human genome. BMC Genomics 10:143. doi:10.1186/1471-2164-10-143
-
(2009)
BMC Genomics
, vol.10
, pp. 143
-
-
Rosenfeld, J.A.1
Wang, Z.2
Schones, D.E.3
Zhao, K.4
Desalle, R.5
Zhang, M.Q.6
-
181
-
-
0035830960
-
Specific interactions of the telomeric protein Rap1p with nucleosomal binding sites
-
Rossetti, L., Cacchione, S., De Menna, A., Chapman, L., Rhodes, D., and Savino, M. (2001). Specific interactions of the telomeric protein Rap1p with nucleosomal binding sites. J. Mol. Biol. 306, 903-913.
-
(2001)
J. Mol. Biol.
, vol.306
, pp. 903-913
-
-
Rossetti, L.1
Cacchione, S.2
De Menna, A.3
Chapman, L.4
Rhodes, D.5
Savino, M.6
-
182
-
-
0032510809
-
Nucleosome assembly on telomeric sequences
-
Rossetti, L., Cacchione, S., Fua, M., and Savino, M. (1998). Nucleosome assembly on telomeric sequences. Biochemistry 37, 6727-6737.
-
(1998)
Biochemistry
, vol.37
, pp. 6727-6737
-
-
Rossetti, L.1
Cacchione, S.2
Fua, M.3
Savino, M.4
-
183
-
-
41449108060
-
Flap endonuclease 1 contributes to telomere stability
-
Saharia, A., Guittat, L., Crocker, S., Lim, A., Steffen, M., Kulkarni, S., et al. (2008). Flap endonuclease 1 contributes to telomere stability. Curr. Biol. 18, 496-500.
-
(2008)
Curr. Biol.
, vol.18
, pp. 496-500
-
-
Saharia, A.1
Guittat, L.2
Crocker, S.3
Lim, A.4
Steffen, M.5
Kulkarni, S.6
-
184
-
-
77956255536
-
FEN1 ensures telomere stability by facilitating replication fork re-initiation
-
Saharia, A., Teasley, D. C., Duxin, J. P., Dao, B., Chiappinelli, K. B., and Stewart, S. A. (2010). FEN1 ensures telomere stability by facilitating replication fork re-initiation. J. Biol. Chem. 285, 27057-27066.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27057-27066
-
-
Saharia, A.1
Teasley, D.C.2
Duxin, J.P.3
Dao, B.4
Chiappinelli, K.B.5
Stewart, S.A.6
-
185
-
-
38849111756
-
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
-
Schoeftner, S., and Blasco, M. A. (2008). Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nat. Cell Biol. 10, 228-236.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 228-236
-
-
Schoeftner, S.1
Blasco, M.A.2
-
186
-
-
0036499971
-
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing
-
Schotta, G., Ebert, A., Krauss, V., Fischer, A., Hoffmann, J., Rea, S., et al. (2002). Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J. 21, 1121-1131.
-
(2002)
EMBO J.
, vol.21
, pp. 1121-1131
-
-
Schotta, G.1
Ebert, A.2
Krauss, V.3
Fischer, A.4
Hoffmann, J.5
Rea, S.6
-
187
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta, G., Lachner, M., Sarma, K., Ebert, A., Sengupta, R., Reuter, G., et al. (2004). A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 18, 1251-1262.
-
(2004)
Genes Dev.
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
-
188
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber, J., Korshunov, A., Liu, X. Y., Jones, D. T., Pfaff, E., Jacob, K., et al. (2012). Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482, 226-231.
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.4
Pfaff, E.5
Jacob, K.6
-
189
-
-
0023788886
-
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis
-
Sen, D., and Gilbert, W. (1988). Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature 334, 364-366.
-
(1988)
Nature
, vol.334
, pp. 364-366
-
-
Sen, D.1
Gilbert, W.2
-
190
-
-
84860456242
-
Removal of shelterin reveals the telomere end-protection problem
-
Sfeir, A., and de Lange, T. (2012). Removal of shelterin reveals the telomere end-protection problem. Science 336, 593-597.
-
(2012)
Science
, vol.336
, pp. 593-597
-
-
Sfeir, A.1
de Lange, T.2
-
191
-
-
67649635974
-
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
-
Sfeir, A., Kosiyatrakul, S. T., Hockemeyer, D., Macrae, S. L., Karlseder, J., Schildkraut, C. L., et al. (2009). Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 138, 90-103.
-
(2009)
Cell
, vol.138
, pp. 90-103
-
-
Sfeir, A.1
Kosiyatrakul, S.T.2
Hockemeyer, D.3
Macrae, S.L.4
Karlseder, J.5
Schildkraut, C.L.6
-
192
-
-
19844382620
-
Senescence and immortalization: role of telomeres and telomerase
-
Shay, J. W., and Wright, W. E. (2005). Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 26, 867-874.
-
(2005)
Carcinogenesis
, vol.26
, pp. 867-874
-
-
Shay, J.W.1
Wright, W.E.2
-
193
-
-
77955847473
-
LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection
-
Sheppard, S. A., and Loayza, D. (2010). LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection. Aging (Albany NY) 2, 432-444.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 432-444
-
-
Sheppard, S.A.1
Loayza, D.2
-
194
-
-
0035313820
-
Telomeric chromatin: replicating and wrapping up chromosome ends
-
Shore, D. (2001). Telomeric chromatin: replicating and wrapping up chromosome ends. Curr. Opin. Genet. Dev. 11, 189-198.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 189-198
-
-
Shore, D.1
-
195
-
-
40949130398
-
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
-
Sinkkonen, L., Hugenschmidt, T., Berninger, P., Gaidatzis, D., Mohn, F., Artus-Revel, C. G., et al. (2008). MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat. Struct. Mol. Biol. 15, 259-267.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 259-267
-
-
Sinkkonen, L.1
Hugenschmidt, T.2
Berninger, P.3
Gaidatzis, D.4
Mohn, F.5
Artus-Revel, C.G.6
-
196
-
-
0034687248
-
Tankyrase promotes telomere elongation in human cells
-
Smith, S., and de Lange, T. (2000). Tankyrase promotes telomere elongation in human cells. Curr. Biol. 10, 1299-1302.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1299-1302
-
-
Smith, S.1
de Lange, T.2
-
197
-
-
35848939383
-
The protein kinase Aurora C phosphorylates TRF2
-
Spengler, D. (2007). The protein kinase Aurora C phosphorylates TRF2. Cell Cycle 6, 2579-2580.
-
(2007)
Cell Cycle
, vol.6
, pp. 2579-2580
-
-
Spengler, D.1
-
198
-
-
0035476710
-
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang
-
Stansel, R. M., De Lange, T., and Griffith, J. D. (2001). T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang. EMBO J. 20, 5532-5540.
-
(2001)
EMBO J.
, vol.20
, pp. 5532-5540
-
-
Stansel, R.M.1
De Lange, T.2
Griffith, J.D.3
-
199
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki, M., Clapperton, J. A., Mohammad, D., Yaffe, M. B., Smerdon, S. J., and Jackson, S. P. (2005). MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123, 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
200
-
-
33846703987
-
SHREC, an effector complex for heterochromatic transcriptional silencing
-
Sugiyama, T., Cam, H. P., Sugiyama, R., Noma, K., Zofall, M., Kobayashi, R., et al. (2007). SHREC, an effector complex for heterochromatic transcriptional silencing. Cell 128, 491-504.
-
(2007)
Cell
, vol.128
, pp. 491-504
-
-
Sugiyama, T.1
Cam, H.P.2
Sugiyama, R.3
Noma, K.4
Zofall, M.5
Kobayashi, R.6
-
201
-
-
0032538453
-
The Bloom' syndrome helicase unwinds G4 DNA
-
Sun, H., Karow, J. K., Hickson, I. D., and Maizels, N. (1998). The Bloom' syndrome helicase unwinds G4 DNA. J. Biol. Chem. 273, 27587-27592.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27587-27592
-
-
Sun, H.1
Karow, J.K.2
Hickson, I.D.3
Maizels, N.4
-
202
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai, H., Smogorzewska, A., and De Lange, T. (2003). DNA damage foci at dysfunctional telomeres. Curr. Biol. 13, 1549-1556.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
De Lange, T.3
-
203
-
-
74049122810
-
In vivo stoichiometry of shelterin components
-
Takai, K. K., Hooper, S., Blackwood, S., Gandhi, R., and De Lange, T. (2010). In vivo stoichiometry of shelterin components. J. Biol. Chem. 285, 1457-1467.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1457-1467
-
-
Takai, K.K.1
Hooper, S.2
Blackwood, S.3
Gandhi, R.4
De Lange, T.5
-
204
-
-
27444434379
-
DNA damage-induced phosphorylation of the human telomere-associated protein TRF2
-
Tanaka, H., Mendonca, M. S., Bradshaw, P. S., Hoelz, D. J., Malkas, L. H., Meyn, M. S., et al. (2005). DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. Proc. Natl. Acad. Sci. U.S.A. 102, 15539-15544.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 15539-15544
-
-
Tanaka, H.1
Mendonca, M.S.2
Bradshaw, P.S.3
Hoelz, D.J.4
Malkas, L.H.5
Meyn, M.S.6
-
205
-
-
80052399287
-
SIRT6 is required for maintenance of telomere position effect in human cells
-
Tennen, R. I., Bua, D. J., Wright, W. E., and Chua, K. F. (2011). SIRT6 is required for maintenance of telomere position effect in human cells. Nat. Commun. 2, 433.
-
(2011)
Nat. Commun.
, vol.2
, pp. 433
-
-
Tennen, R.I.1
Bua, D.J.2
Wright, W.E.3
Chua, K.F.4
-
206
-
-
78650889400
-
Chromatin regulation and genome maintenance by mammalian SIRT6
-
Tennen, R. I., and Chua, K. F. (2011). Chromatin regulation and genome maintenance by mammalian SIRT6. Trends Biochem. Sci. 36, 39-46.
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 39-46
-
-
Tennen, R.I.1
Chua, K.F.2
-
207
-
-
10944271790
-
Taz1 binding to a fission yeast model telomere: formation of telomeric loops and higher order structures
-
Tomaska, L., Willcox, S., Slezakova, J., Nosek, J., and Griffith, J. D. (2004). Taz1 binding to a fission yeast model telomere: formation of telomeric loops and higher order structures. J. Biol. Chem. 279, 50764-50772.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50764-50772
-
-
Tomaska, L.1
Willcox, S.2
Slezakova, J.3
Nosek, J.4
Griffith, J.D.5
-
208
-
-
0028101019
-
Unusual chromatin in human telomeres
-
Tommerup, H., Dousmanis, A., and De Lange, T. (1994). Unusual chromatin in human telomeres. Mol. Cell. Biol. 14, 5777-5785.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5777-5785
-
-
Tommerup, H.1
Dousmanis, A.2
De Lange, T.3
-
209
-
-
84860854071
-
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
-
Vannier, J. B., Pavicic-Kaltenbrunner, V., Petalcorin, M. I., Ding, H., and Boulton, S. J. (2012). RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell 149, 795-806.
-
(2012)
Cell
, vol.149
, pp. 795-806
-
-
Vannier, J.B.1
Pavicic-Kaltenbrunner, V.2
Petalcorin, M.I.3
Ding, H.4
Boulton, S.J.5
-
210
-
-
79953675088
-
Arabidopsis thaliana telomeres exhibit euchromatic features
-
Vaquero-Sedas, M. I., Gamez-Arjona, F. M., and Vega-Palas, M. A. (2011). Arabidopsis thaliana telomeres exhibit euchromatic features. Nucleic Acids Res. 39, 2007-2017.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 2007-2017
-
-
Vaquero-Sedas, M.I.1
Gamez-Arjona, F.M.2
Vega-Palas, M.A.3
-
211
-
-
84870589400
-
Analysis of the epigenetic status of telomeres by using ChIP-seq data
-
Vaquero-Sedas, M. I., Luo, C., and Vega-Palas, M. A. (2012). Analysis of the epigenetic status of telomeres by using ChIP-seq data. Nucleic Acids Res. 40, e163.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Vaquero-Sedas, M.I.1
Luo, C.2
Vega-Palas, M.A.3
-
212
-
-
27944496124
-
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
-
Verdun, R. E., Crabbe, L., Haggblom, C., and Karlseder, J. (2005). Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. Mol. Cell 20, 551-561.
-
(2005)
Mol. Cell
, vol.20
, pp. 551-561
-
-
Verdun, R.E.1
Crabbe, L.2
Haggblom, C.3
Karlseder, J.4
-
213
-
-
0037077223
-
Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins
-
von Kobbe, C., Karmakar, P., Dawut, L., Opresko, P., Zeng, X., Brosh, R. M. Jr., et al. (2002). Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins. J. Biol. Chem. 277, 22035-22044.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22035-22044
-
-
von Kobbe, C.1
Karmakar, P.2
Dawut, L.3
Opresko, P.4
Zeng, X.5
Brosh Jr., R.M.6
-
214
-
-
77954165748
-
siRNA-mediated methylation of Arabidopsis telomeres
-
doi:10.1371/journal.pgen.1000986
-
Vrbsky, J., Akimcheva, S., Watson, J. M., Turner, T. L., Daxinger, L., Vyskot, B., et al. (2010). siRNA-mediated methylation of Arabidopsis telomeres. PLoS Genet. 6:e1000986. doi:10.1371/journal.pgen.1000986
-
(2010)
PLoS Genet.
, vol.6
-
-
Vrbsky, J.1
Akimcheva, S.2
Watson, J.M.3
Turner, T.L.4
Daxinger, L.5
Vyskot, B.6
-
215
-
-
33846691378
-
The POT1-TPP1 telomere complex is a telomerase processivity factor
-
Wang, F., Podell, E. R., Zaug, A. J., Yang, Y., Baciu, P., Cech, T. R., et al. (2007). The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature 445, 506-510.
-
(2007)
Nature
, vol.445
, pp. 506-510
-
-
Wang, F.1
Podell, E.R.2
Zaug, A.J.3
Yang, Y.4
Baciu, P.5
Cech, T.R.6
-
216
-
-
68149110347
-
Ku86 represses lethal telomere deletion events in human somatic cells
-
Wang, Y., Ghosh, G., and Hendrickson, E. A. (2009). Ku86 represses lethal telomere deletion events in human somatic cells. Proc. Natl. Acad. Sci. U.S.A. 106, 12430-12435.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 12430-12435
-
-
Wang, Y.1
Ghosh, G.2
Hendrickson, E.A.3
-
217
-
-
0015515155
-
Origin of concatemeric T7 DNA
-
Watson, J. D. (1972). Origin of concatemeric T7 DNA. Nature New Biol. 239, 197-201.
-
(1972)
Nature New Biol.
, vol.239
, pp. 197-201
-
-
Watson, J.D.1
-
218
-
-
84865105439
-
Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end
-
Wellinger, R. J., and Zakian, V. A. (2012). Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. Genetics 191, 1073-1105.
-
(2012)
Genetics
, vol.191
, pp. 1073-1105
-
-
Wellinger, R.J.1
Zakian, V.A.2
-
219
-
-
62449198947
-
Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence
-
Williams, E. S., Klingler, R., Ponnaiya, B., Hardt, T., Schrock, E., Lees-Miller, S. P., et al. (2009). Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence. Cancer Res. 69, 2100-2107.
-
(2009)
Cancer Res.
, vol.69
, pp. 2100-2107
-
-
Williams, E.S.1
Klingler, R.2
Ponnaiya, B.3
Hardt, T.4
Schrock, E.5
Lees-Miller, S.P.6
-
220
-
-
77649262618
-
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
-
Wong, L. H., McGhie, J. D., Sim, M., Anderson, M. A., Ahn, S., Hannan, R. D., et al. (2010). ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res. 20, 351-360.
-
(2010)
Genome Res.
, vol.20
, pp. 351-360
-
-
Wong, L.H.1
McGhie, J.D.2
Sim, M.3
Anderson, M.A.4
Ahn, S.5
Hannan, R.D.6
-
221
-
-
0026563895
-
Saccharomyces telomeres assume a non-nucleosomal chromatin structure
-
Wright, J. H., Gottschling, D. E., and Zakian, V. A. (1992). Saccharomyces telomeres assume a non-nucleosomal chromatin structure. Genes Dev. 6, 197-210.
-
(1992)
Genes Dev.
, vol.6
, pp. 197-210
-
-
Wright, J.H.1
Gottschling, D.E.2
Zakian, V.A.3
-
222
-
-
0034730633
-
NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres
-
Wu, G., Lee, W. H., and Chen, P. L. (2000). NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. J. Biol. Chem. 275, 30618-30622.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30618-30622
-
-
Wu, G.1
Lee, W.H.2
Chen, P.L.3
-
223
-
-
51349167747
-
No overt nucleosome eviction at deprotected telomeres
-
Wu, P., and de Lange, T. (2008). No overt nucleosome eviction at deprotected telomeres. Mol. Cell. Biol. 28, 5724-5735.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5724-5735
-
-
Wu, P.1
de Lange, T.2
-
224
-
-
77955995270
-
Apollo contributes to G overhang maintenance and protects leading-end telomeres
-
Wu, P., Van Overbeek, M., Rooney, S., and De Lange, T. (2010). Apollo contributes to G overhang maintenance and protects leading-end telomeres. Mol. Cell 39, 606-617.
-
(2010)
Mol. Cell
, vol.39
, pp. 606-617
-
-
Wu, P.1
Van Overbeek, M.2
Rooney, S.3
De Lange, T.4
-
225
-
-
34548492016
-
MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control
-
Wu, Y., Xiao, S., and Zhu, X. D. (2007a). MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control. Nat. Struct. Mol. Biol. 14, 832-840.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 832-840
-
-
Wu, Y.1
Xiao, S.2
Zhu, X.D.3
-
226
-
-
33846210498
-
XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening
-
Wu, Y., Zacal, N. J., Rainbow, A. J., and Zhu, X. D. (2007b). XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening. DNA Repair (Amst.) 6, 157-166.
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 157-166
-
-
Wu, Y.1
Zacal, N.J.2
Rainbow, A.J.3
Zhu, X.D.4
-
227
-
-
54449087207
-
Plk1 phosphorylation of TRF1 is essential for its binding to telomeres
-
Wu, Z. Q., Yang, X., Weber, G., and Liu, X. (2008). Plk1 phosphorylation of TRF1 is essential for its binding to telomeres. J. Biol. Chem. 283, 25503-25513.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 25503-25513
-
-
Wu, Z.Q.1
Yang, X.2
Weber, G.3
Liu, X.4
-
228
-
-
79851496150
-
Histone H4 lysine 12 acetylation regulates telomeric heterochromatin plasticity in Saccharomyces cerevisiae
-
doi:10.1371/journal.pgen.1001272
-
Zhou, B. O., Wang, S. S., Zhang, Y., Fu, X. H., Dang, W., Lenzmeier, B. A., et al. (2011). Histone H4 lysine 12 acetylation regulates telomeric heterochromatin plasticity in Saccharomyces cerevisiae. PLoS Genet. 7:e1001272. doi:10.1371/journal.pgen.1001272
-
(2011)
PLoS Genet.
, vol.7
-
-
Zhou, B.O.1
Wang, S.S.2
Zhang, Y.3
Fu, X.H.4
Dang, W.5
Lenzmeier, B.A.6
-
229
-
-
0035798379
-
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
-
Zhou, X. Z., and Lu, K. P. (2001). The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. Cell 107, 347-359.
-
(2001)
Cell
, vol.107
, pp. 347-359
-
-
Zhou, X.Z.1
Lu, K.P.2
-
230
-
-
66349094239
-
GNL3L stabilizes the TRF1 complex and promotes mitotic transition
-
Zhu, Q., Meng, L., Hsu, J. K., Lin, T., Teishima, J., and Tsai, R. Y. (2009). GNL3L stabilizes the TRF1 complex and promotes mitotic transition. J. Cell Biol. 185, 827-839.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 827-839
-
-
Zhu, Q.1
Meng, L.2
Hsu, J.K.3
Lin, T.4
Teishima, J.5
Tsai, R.Y.6
-
231
-
-
33845387497
-
Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability
-
Zhu, Q., Yasumoto, H., and Tsai, R. Y. (2006). Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability. Mol. Cell. Biol. 26, 9279-9290.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 9279-9290
-
-
Zhu, Q.1
Yasumoto, H.2
Tsai, R.Y.3
-
232
-
-
0342561644
-
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
-
Zhu, X. D., Kuster, B., Mann, M., Petrini, J. H., and De Lange, T. (2000). Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat. Genet. 25, 347-352.
-
(2000)
Nat. Genet.
, vol.25
, pp. 347-352
-
-
Zhu, X.D.1
Kuster, B.2
Mann, M.3
Petrini, J.H.4
De Lange, T.5
-
233
-
-
0347416975
-
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
-
Zhu, X. D., Niedernhofer, L., Kuster, B., Mann, M., Hoeijmakers, J. H., and De Lange, T. (2003). ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes. Mol. Cell 12, 1489-1498.
-
(2003)
Mol. Cell
, vol.12
, pp. 1489-1498
-
-
Zhu, X.D.1
Niedernhofer, L.2
Kuster, B.3
Mann, M.4
Hoeijmakers, J.H.5
De Lange, T.6
|