Isolation and Hepatocyte Differentiation of Mesenchymal Stem Cells From Porcine Bone Marrow—“Surgical Waste” as a Novel MSC Source

Transplantation Proceedings

Volumn 45, Issue 5, 2013, Pages 2056-2058

  Bruckner S ^a   Tautenhahn, H M ^a   Winkler, S ^a   Stock, P ^a   Jonas, S ^a   Dollinger, M ^b   Christ, B ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; CYTOCHROME P450 1A; CYTOCHROME P450 2B1; ENDOGLIN; FAS ANTIGEN; GLYCOGEN; HERMES ANTIGEN; THY 1 ANTIGEN; LEUKOCYTE ANTIGEN;

ADIPOCYTE; ADULT; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BONE BIOPSY; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; FEMUR; FLOW CYTOMETRY; GLYCOGEN SYNTHESIS; ILIAC CREST; LANDRACE PIG; LIVER CELL; NONHUMAN; OSTEOCYTE; PRIORITY JOURNAL; UREA CYCLE; ANIMAL; BONE MARROW CELL; CYTOLOGY; IMMUNOLOGY; MESENCHYMAL STROMA CELL; SWINE;

ANIMALS; ANTIGENS, CD; BONE MARROW CELLS; CELL DIFFERENTIATION; HEPATOCYTES; MESENCHYMAL STROMAL CELLS; SWINE;

EID: 84890731475     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2013.01.101     Document Type: Article

References (12)

1. Bilir, B.M., Guinette, D., Karrer, F., et al. Hepatocyte transplantation in acute liver failure. Liver Transpl 6:1 (2000), 32–40.
2. Habibullah, C.M., Syed, I.H., Qamar, A., et al. Human fetal hepatocyte transplantation in patients with fulminant hepatic failure. Transplantation 58:8 (1994), 951–952.
3. Fox, I.J., Chowdhury, J.R., Kaufman, S.S., et al. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 338:20 (1998), 1422–1426.
4. Horslen, S.P., McCowan, T.C., Goertzen, T.C., et al. Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder. Pediatrics 111:6 Pt 1 (2003), 1262–1267.
5. Aurich, I., Mueller, L.P., Aurich, H., et al. Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers. Gut 56:3 (2007), 405–415.
6. Groth, A., Ottinger, S., Kleist, C., et al. Evaluation of porcine mesenchymal stem cells for therapeutic use in human liver cancer. Int J Oncol 40:2 (2012), 391–401.
7. Lange, C., Bassler, P., Lioznov, M.V., et al. Hepatocytic gene expression in cultured rat mesenchymal stem cells. Transplant Proc 37:1 (2005), 276–279.
8. Wang, P.P., Wang, J.H., Yan, Z.P., et al. Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction. Biochem Biophys Res Commun 320:3 (2004), 712–716.
9. Rasmusson, I., Immune modulation by mesenchymal stem cells. Exp Cell Res 312:12 (2006), 2169–2179.
10. Stock, P., Bruckner, S., Ebensing, S., et al. The generation of hepatocytes from mesenchymal stem cells and engraftment into murine liver. Nature Protocols 5:4 (2010), 617–627.
11. Seglen, P.O., Preparation of isolated rat liver cells. Methods Cell Biol 13 (1976), 29–83.
12. Christ, B., Pelz, S., Implication of hepatic stem cells in functional liver repopulation. Cytometry A 83:1 (2013), 90–102.