The role of postmastectomy radiation therapy after neoadjuvant chemotherapy in clinical stage II-III breast cancer patients with pN0: A multicenter, retrospective study (KROG 12-05)

International Journal of Radiation Oncology Biology Physics

Volumn 88, Issue 1, 2014, Pages 65-72

  Shim, Su Jung ^a   Park, Won ^b   Huh, Seung Jae ^b   Choi, Doo Ho ^b   Shin, Kyung Hwan ^c   Lee, Nam Kwon ^c,d   Suh, Chang Ok ^e   Keum, Ki Chang ^e   Kim, Yong Bae ^e   Ahn, Seung Do ^f   Kim, Su Ssan ^f   Ha, Sung W ^g   Chie, Eui Kyu ^g   Kim, Kyubo ^g   Shin, Hyun Soo ^h   Kim, Jin Hee ⁱ   Lee, Hyung Sik ^j  

^a Eulji General Hospital   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c National Cancer Center   (South Korea)

^d Korea University College of Medicine   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f University of Ulsan College of Medicine   (South Korea)

^g Seoul National University   (South Korea)

^h CHA University   (South Korea)

ⁱ Keimyung University   (South Korea)

^j Dong A University College of Medicine   (South Korea)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CONFIDENCE INTERVAL; DISEASE-FREE SURVIVAL; METHODS AND MATERIALS; MULTI VARIATE ANALYSIS; NEOADJUVANT CHEMOTHERAPIES; POSTMASTECTOMY RADIATION THERAPIES; RANDOMIZED CLINICAL TRIALS; RECURRENCE-FREE SURVIVAL;

CHEMOTHERAPY; MULTIVARIANT ANALYSIS; PATHOLOGY; RADIOTHERAPY; REGRESSION ANALYSIS;

DISEASES;

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; METHOTREXATE; TAXANE DERIVATIVE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER HORMONE THERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DISTANT METASTASIS; FOLLOW UP; HUMAN; LOCAL RECURRENCE FREE SURVIVAL; MAJOR CLINICAL STUDY; MULTICENTER STUDY (TOPIC); MULTIMODALITY CANCER THERAPY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PARTIAL MASTECTOMY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TREATMENT FAILURE;

ADULT; AGE FACTORS; AGED; ANALYSIS OF VARIANCE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LINEAR MODELS; LYMPH NODE EXCISION; MASTECTOMY; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES;

EID: 84890560529     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.09.021     Document Type: Article

References (26)

1. H.D. Bear, S. Anderson, and R.E. Smith Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27 J Clin Oncol 24 2006 2019 2027
2. J.R. Gralow, H.J. Burstein, and W. Wood Preoperative therapy in invasive breast cancer: Pathologic assessment and systemic therapy issues in operable disease J Clin Oncol 26 2008 814 819
3. G. Bonadonna, U. Veronesi, and C. Brambilla Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more J Natl Cancer Inst 82 1990 1539 1545
4. B. Fisher, A. Brown, and E. Mamounas Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: Findings from National Surgical Adjuvant Breast and Bowel Project B-18 J Clin Oncol 15 1997 2483 2493
5. M. Overgaard, P.S. Hansen, and J. Overgaard Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b trial N Engl J Med 337 1997 949 955
6. M. Overgaard, M.B. Jensen, and J. Overgaard Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial Lancet 353 1999 1641 1648
7. J. Ragaz, S.M. Jackson, and N. Le Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer N Engl J Med 337 1997 956 962
8. T.A. Buchholz, S.L. Tucker, and L. Masullo Predictors of local-regional recurrence after neoadjuvant chemotherapy and mastectomy without radiation J Clin Oncol 20 2002 17 23
9. A.M. Chen, F. Meric-Bernstam, and K.K. Hunt Breast conservation after neoadjuvant chemotherapy: The MD Anderson Cancer Center experience J Clin Oncol 22 2004 2303 2312
10. A.K. Garg, E.A. Strom, and M.D. McNeese T3 disease at presentation or pathologic involvement of four or more lymph nodes predict for locoregional recurrence in stage II breast cancer treated with neoadjuvant chemotherapy and mastectomy without radiotherapy Int J Radiat Oncol Biol Phys 59 2004 138 145
11. E.H. Huang, S.L. Tucker, and E.A. Strom Postmastectomy radiation improves local-regional control and survival for selected patients with locally advanced breast cancer treated with neoadjuvant chemotherapy and mastectomy J Clin Oncol 22 2004 4691 4699
12. S.E. McGuire, A.M. Gonzalez-Angulo, and E.H. Huang Postmastectomy radiation improves the outcome of patients with locally advanced breast cancer who achieve a pathologic complete response to neoadjuvant chemotherapy Int J Radiat Oncol Biol Phys 68 2007 1004 1009
13. H. Nagar, E.A. Mittendorf, and E.A. Strom Local-regional recurrence with and without radiation therapy after neoadjuvant chemotherapy and mastectomy for clinically staged T3N0 breast cancer Int J Radiat Oncol Biol Phys 81 2011 782 787
14. T.A. Buchholz, C.D. Lehman, and J.R. Harris Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: A National Cancer Institute conference J Clin Oncol 26 2008 791 797
15. C. Daveau, D. Stevens, and E. Brain Is regional lymph node irradiation necessary in stage II to III breast cancer patients with negative pathologic node status after neoadjuvant chemotherapy? Int J Radiat Oncol Biol Phys 78 2010 337 342
16. R. Le Scodan, J. Selz, and D. Stevens Radiotherapy for stage II and stage III breast cancer patients with negative lymph nodes after preoperative chemotherapy and mastectomy Int J Radiat Oncol Biol Phys 82 2012 e1 e7
17. Danish Breast Cancer Cooperative Group, H.M. Nielsen, M. Overgaard, and C. Grau Study of failure pattern among high-risk breast cancer patients with or without postmastectomy radiotherapy in addition to adjuvant systemic therapy: Long-term results from the Danish Breast Cancer Cooperative Group DBCG 82 b and c randomized studies J Clin Oncol 24 2006 2268 2275
18. A. Katz, E.A. Strom, and T.A. Buchholz Locoregional recurrence patterns after mastectomy and doxorubicin-based chemotherapy: Implications for postoperative irradiation J Clin Oncol 18 2000 2817 2827
19. A. Recht, R. Gray, and N.E. Davidson Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: Experience of the Eastern Cooperative Oncology Group J Clin Oncol 17 1999 1689 1700
20. A. Taghian, J.H. Jeong, and E. Mamounas Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: Results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials J Clin Oncol 22 2004 4247 4254
21. A. Wallgren, M. Bonetti, and R.D. Gelber Risk factors for locoregional recurrence among breast cancer patients: Results from International Breast Cancer Study Group Trials I through VII J Clin Oncol 21 2003 1205 1213
22. M. Clarke, R. Collins, and S. Darby Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials Lancet 366 2005 2087 2106
23. P. Rastogi, S.J. Anderson, and H.D. Bear Preoperative chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27 J Clin Oncol 26 2008 778 785
24. T.P. Mamounas Predicting locoregional recurrence after neoadjuvant chemotherapy in patients with breast cancer Clin Adv Hematol Oncol 11 2013 175 177
25. L.S. Dominici, V.M. Negron Gonzalez, and A.U. Buzdar Cytologically proven axillary lymph node metastases are eradicated in patients receiving preoperative chemotherapy with concurrent trastuzumab for HER 2-positive breast cancer Cancer 116 2010 2884 2889
26. T.A. Buchholz, A. Katz, and E.A. Strom Pathologic tumor size and lymph node status predict for different rates of locoregional recurrence after mastectomy for breast cancer patients treated with neoadjuvant versus adjuvant chemotherapy Int J Radiat Oncol Biol Phys 53 2002 880 888