메뉴 건너뛰기




Volumn 29, Issue 1, 2014, Pages 1-11

Radiometabolic treatment of bone-metastasizing cancer: From 186rhenium to 223radium

Author keywords

Bone metastases; Molecular imaging; Myelosuppression; Radionuclide therapy; Radiopharmaceuticals

Indexed keywords

ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; PHOSPHORUS 32; RADIUM CHLORIDE RA 223; RHENIUM 186; RHENIUM 188; SAMARIUM 153; STRONTIUM 89;

EID: 84890531221     PISSN: 10849785     EISSN: 15578852     Source Type: Journal    
DOI: 10.1089/cbr.2013.1549     Document Type: Review
Times cited : (52)

References (74)
  • 1
    • 2942685488 scopus 로고    scopus 로고
    • The pathophysiology of cancer-induced bone pain: Current understanding
    • Urch C. The pathophysiology of cancer-induced bone pain: Current understanding. Palliat Med 2004;18:267.
    • (2004) Palliat Med , vol.18 , pp. 267
    • Urch, C.1
  • 2
    • 34547104372 scopus 로고    scopus 로고
    • Bone seeking radiopharmaceuticals for palliation of pain in cancer patients with osseous metastases
    • Lam MG, De Klerk JM, Van Rijk PP, et al. Bone seeking radiopharmaceuticals for palliation of pain in cancer patients with osseous metastases. Anticancer Agents Med Chem 2007;7:381.
    • (2007) Anticancer Agents Med Chem , vol.7 , pp. 381
    • Lam, M.G.1    De Klerk, J.M.2    Van Rijk, P.P.3
  • 3
    • 40649090942 scopus 로고    scopus 로고
    • Molecular mechanisms and treatment of bone metastasis
    • Clines GA, Guise TA. Molecular mechanisms and treatment of bone metastasis. Expert Rev Mol Med 2008;10:e7.
    • (2008) Expert Rev Mol Med , vol.10
    • Clines, G.A.1    Guise, T.A.2
  • 4
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002;2:584.
    • (2002) Nat Rev Cancer , vol.2 , pp. 584
    • Mundy, G.R.1
  • 5
    • 74949105909 scopus 로고    scopus 로고
    • Systemic metabolic radiopharmaceutical therapy in the treatment of metastatic bone pain
    • Paes FM, Serafini AN. Systemic metabolic radiopharmaceutical therapy in the treatment of metastatic bone pain. Semin Nucl Med 2010;40:89.
    • (2010) Semin Nucl Med , vol.40 , pp. 89
    • Paes, F.M.1    Serafini, A.N.2
  • 6
    • 0036119093 scopus 로고    scopus 로고
    • Pain measurement tools and methods in clinical research in palliative care: Recommendations of an Expert Working Group of the European Association of Palliative Care
    • Caraceni A, Chern N, Fainsinger R, et al. Pain measurement tools and methods in clinical research in palliative care: Recommendations of an Expert Working Group of the European Association of Palliative Care. J Pain Symptom Manage 2002;23:239.
    • (2002) J Pain Symptom Manage , vol.23 , pp. 239
    • Caraceni, A.1    Chern, N.2    Fainsinger, R.3
  • 7
    • 82955162692 scopus 로고    scopus 로고
    • Internal radiotherapy of painful bone metastases
    • Liepe K, Kotzerke J. Internal radiotherapy of painful bone metastases. Methods 2011;55:258.
    • (2011) Methods , vol.55 , pp. 258
    • Liepe, K.1    Kotzerke, J.2
  • 8
    • 0026689779 scopus 로고
    • A report of RTOG 8206: A phase III study of whether the addition of single dose hemibody irradiation to standard fractionated local field irradiation is more effective than local field irradiation alone in the treatment of symptomatic osseous metastases
    • Poulter CA, Cosmatos D, Rubin P, et al. A report of RTOG 8206: A phase III study of whether the addition of single dose hemibody irradiation to standard fractionated local field irradiation is more effective than local field irradiation alone in the treatment of symptomatic osseous metastases. Int J Radiat Oncol Biol Phys 1992;23:207.
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 207
    • Poulter, C.A.1    Cosmatos, D.2    Rubin, P.3
  • 9
    • 0029610306 scopus 로고
    • The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation
    • Jadad AR, Browman GP. The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation. J Am Med Assoc 1995;274:1870.
    • (1995) J Am Med Assoc , vol.274 , pp. 1870
    • Jadad, A.R.1    Browman, G.P.2
  • 11
    • 84856619689 scopus 로고    scopus 로고
    • Update on the systematic review of palliative radiotherapy trials for bone metastases
    • Chow E, Zeng L, Salvo N, et al. Update on the systematic review of palliative radiotherapy trials for bone metastases. Clin Oncol (R. Coll. Radiol.) 2012;24:112.
    • (2012) Clin Oncol (R. Coll. Radiol.) , vol.24 , pp. 112
    • Chow, E.1    Zeng, L.2    Salvo, N.3
  • 12
    • 79959362605 scopus 로고    scopus 로고
    • A treatment planning method for sequentially combining radiopharmaceutical therapy and external radiation therapy
    • Hobbs RF, McNutt T, Baechler S, et al. A treatment planning method for sequentially combining radiopharmaceutical therapy and external radiation therapy. Int J Radiat Oncol Biol Phys 2011;80:1256.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 1256
    • Hobbs, R.F.1    McNutt, T.2    Baechler, S.3
  • 13
    • 84863093187 scopus 로고    scopus 로고
    • Bone-targeting radiopharmaceuticals for the treatment of prostate cancer with bone metastases
    • Goyal J, Antonarakis ES. Bone-targeting radiopharmaceuticals for the treatment of prostate cancer with bone metastases. Cancer Lett 2012;323:135.
    • (2012) Cancer Lett , vol.323 , pp. 135
    • Goyal, J.1    Antonarakis, E.S.2
  • 14
    • 0033923590 scopus 로고    scopus 로고
    • Systemic radiopharmaceuticals therapy of painful osteoblastic metastases
    • Silberstein EB. Systemic radiopharmaceuticals therapy of painful osteoblastic metastases. Semin Radiat Oncol 2000; 10:240.
    • (2000) Semin Radiat Oncol , vol.10 , pp. 240
    • Silberstein, E.B.1
  • 15
    • 14844361408 scopus 로고    scopus 로고
    • Bone-seeking radiopharmaceuticals
    • Lewington VJ. Bone-seeking radiopharmaceuticals. J Nucl Med 2005;46:38S.
    • (2005) J Nucl Med , vol.46
    • Lewington, V.J.1
  • 16
    • 19944386284 scopus 로고    scopus 로고
    • Radioisotopes for the palliation of metastatic bone cancer: A systematic review
    • Finlay IG, Mason MD, Shelley M. Radioisotopes for the palliation of metastatic bone cancer: A systematic review. Lancet Oncol 2005;6:392.
    • (2005) Lancet Oncol , vol.6 , pp. 392
    • Finlay, I.G.1    Mason, M.D.2    Shelley, M.3
  • 17
    • 52449095881 scopus 로고    scopus 로고
    • EANM procedure guideline for treatment of refractory metastatic bone pain
    • Bodei L, Lam M, Chiesa C, et al. EANM procedure guideline for treatment of refractory metastatic bone pain. Eur J Nucl Med Mol Imaging 2008;35:1934.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 1934
    • Bodei, L.1    Lam, M.2    Chiesa, C.3
  • 18
    • 33846034920 scopus 로고    scopus 로고
    • Targeted and systemic radiotherapy in the treatment of bone metastasis
    • Lin A, Ray ME. Targeted and systemic radiotherapy in the treatment of bone metastasis. Cancer Metastasis Rev 2006; 25:669.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 669
    • Lin, A.1    Ray, M.E.2
  • 19
    • 0027270333 scopus 로고
    • The treatment of painful osseous metastases with phosphorus-32-labeled phosphates
    • Silberstein EB. The treatment of painful osseous metastases with phosphorus-32-labeled phosphates. Semin Oncol 1993; 20(3suppl2):10.
    • (1993) Semin Oncol , vol.20 , Issue.3 SUPPL. 2 , pp. 10
    • Silberstein, E.B.1
  • 20
    • 0027491534 scopus 로고
    • Strontium-89-precursor targeted therapy for pain relief of blastic metastatic disease
    • Robinson RG. Strontium-89-precursor targeted therapy for pain relief of blastic metastatic disease. Cancer 1993; 72(11Suppl):3433.
    • (1993) Cancer , vol.72 SUPPL. , Issue.11 , pp. 3433
    • Robinson, R.G.1
  • 21
    • 0028073783 scopus 로고
    • Strontium-89 for the palliation of bone pain due to metastatic disease
    • Taylor AJ Jr. Strontium-89 for the palliation of bone pain due to metastatic disease. J Nucl Med 1994;35:2054.
    • (1994) J Nucl Med , vol.35 , pp. 2054
    • Taylor Jr., A.J.1
  • 22
    • 0023901242 scopus 로고
    • Strontium-89 therapy: Measurement of absorbed dose to skeletal metastases
    • Blake GM, Zivanovic MA, Blaquiere RM, et al. Strontium-89 therapy: Measurement of absorbed dose to skeletal metastases. J Nucl Med 1988;29:549.
    • (1988) J Nucl Med , vol.29 , pp. 549
    • Blake, G.M.1    Zivanovic, M.A.2    Blaquiere, R.M.3
  • 23
    • 0034230667 scopus 로고    scopus 로고
    • Usefulness of strontium-89 for bone pain palliation in metastatic breast cancer patients
    • Fuster D, Herranz D, Vidal-Sicart S, et al. Usefulness of strontium-89 for bone pain palliation in metastatic breast cancer patients. Nucl Med Commun 2000;21:623.
    • (2000) Nucl Med Commun , vol.21 , pp. 623
    • Fuster, D.1    Herranz, D.2    Vidal-Sicart, S.3
  • 24
    • 0034948488 scopus 로고    scopus 로고
    • Predictors of response to strontium-89 (Metastron) in skeletal metastases from prostate cancer: Report of a single centre's 10-year experience
    • Windsor PM. Predictors of response to strontium-89 (Metastron) in skeletal metastases from prostate cancer: Report of a single centre's 10-year experience. Clin Oncol (R Coll Radiol) 2001;13:219.
    • (2001) Clin Oncol (R Coll Radiol) , vol.13 , pp. 219
    • Windsor, P.M.1
  • 25
    • 0027252452 scopus 로고
    • Results of a randomized phase III trial to evaluate the efficacy of strontium- 89 adjuvant to local field external-beam irradiation in the management of endocrine-resistant metastatic prostate cancer
    • Porter AT, McEwan AJB, Powe JE, et al. Results of a randomized phase III trial to evaluate the efficacy of strontium- 89 adjuvant to local field external-beam irradiation in the management of endocrine-resistant metastatic prostate cancer. Int J Radiat Oncol Biol Phys 1993;25:805.
    • (1993) Int J Radiat Oncol Biol Phys , vol.25 , pp. 805
    • Porter, A.T.1    McEwan, A.J.B.2    Powe, J.E.3
  • 26
    • 0142259750 scopus 로고    scopus 로고
    • Strontium (89) chloride versus palliative local field radiotherapy in patients with hormonal escaped prostate cancer: A phase III study of the European Organisation of Research and Treatment of Cancer, Genitourinary Group
    • Oosterhof GO, Roberts JT, de Reijke TM, et al. Strontium (89) chloride versus palliative local field radiotherapy in patients with hormonal escaped prostate cancer: A phase III study of the European Organisation of Research and Treatment of Cancer, Genitourinary Group. Eur Urol 2003;44:519.
    • (2003) Eur Urol , vol.44 , pp. 519
    • Oosterhof, G.O.1    Roberts, J.T.2    De Reijke, T.M.3
  • 27
    • 0028233520 scopus 로고
    • A comparison of the palliative effects of strontium-89 and external beam radiotherapy in metastatic prostate cancer
    • Quilty PM, Kirk D, Bolger JJ, et al. A comparison of the palliative effects of strontium-89 and external beam radiotherapy in metastatic prostate cancer. Radiother Oncol 1994; 31:33.
    • (1994) Radiother Oncol , vol.31 , pp. 33
    • Quilty, P.M.1    Kirk, D.2    Bolger, J.J.3
  • 28
    • 0035798930 scopus 로고    scopus 로고
    • Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: A randomised phase II trial
    • Tu SM, Millikan RE, Mengistu B, et al. Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: A randomised phase II trial. Lancet 2001;357:336.
    • (2001) Lancet , vol.357 , pp. 336
    • Tu, S.M.1    Millikan, R.E.2    Mengistu, B.3
  • 29
    • 18044378963 scopus 로고    scopus 로고
    • Palliation of bone pain in prostate cancer using chemotherapy and strontium-89. A randomized phase II study
    • Nilsson S, Strang P, Ginman C, et al. Palliation of bone pain in prostate cancer using chemotherapy and strontium-89. A randomized phase II study. J Pain Symptom Manage 2005; 29:352.
    • (2005) J Pain Symptom Manage , vol.29 , pp. 352
    • Nilsson, S.1    Strang, P.2    Ginman, C.3
  • 30
    • 0030977945 scopus 로고    scopus 로고
    • Treatment of metastatic bone pain using the bone seeking radiopharmaceutical Re-186-HEDP
    • De Klerk JM, Zonnenberg BA, Blijham GH, et al. Treatment of metastatic bone pain using the bone seeking radiopharmaceutical Re-186-HEDP. Anticancer Res 1997;17:1773.
    • (1997) Anticancer Res , vol.17 , pp. 1773
    • De Klerk, J.M.1    Zonnenberg, B.A.2    Blijham, G.H.3
  • 31
    • 0025358769 scopus 로고
    • Re.186(Sn) HEDP for treatment of painful osseous metastases: Initial clinical experience in 20 patients with hormone-resistant prostate cancer
    • Maxon III HR, Schroder LE, Thomas SR, et al. Re.186(Sn) HEDP for treatment of painful osseous metastases: Initial clinical experience in 20 patients with hormone-resistant prostate cancer. Radiology 1990;176:155.
    • (1990) Radiology , vol.176 , pp. 155
    • Maxon III, H.R.1    Schroder, L.E.2    Thomas, S.R.3
  • 32
    • 0034079651 scopus 로고    scopus 로고
    • Short and long-term effects of 185Re-1,1-hydroxyethylidene diphosphonate in the treatment of painful bone metastases
    • Sciuto R, Tofani A, Festa D, et al. Short and long-term effects of 185Re-1,1-hydroxyethylidene diphosphonate in the treatment of painful bone metastases. J Nucl Med 2000; 41:647.
    • (2000) J Nucl Med , vol.41 , pp. 647
    • Sciuto, R.1    Tofani, A.2    Festa, D.3
  • 33
    • 0036733694 scopus 로고    scopus 로고
    • The PLACORHEN study: A double-blind, placebo-controlled, randomized radiounclide study with (186)Re-etidronate in hormone-resistant prostate cancer patients with painful bone metastases. Placebo Controlled Rhenium Study
    • Han SH, DE Klerk JM, Tan S, et al. The PLACORHEN study: A double-blind, placebo-controlled, randomized radiounclide study with (186)Re-etidronate in hormone-resistant prostate cancer patients with painful bone metastases. Placebo Controlled Rhenium Study. J Nucl Med 2002;43:1150.
    • (2002) J Nucl Med , vol.43 , pp. 1150
    • Han, S.H.1    De Klerk, J.M.2    Tan, S.3
  • 34
    • 3042623522 scopus 로고    scopus 로고
    • 186Re-HEDP for metastatic bone pain in breast cancer patients
    • Lam MG, De Klerk JM, Tan S, et al. 186Re-HEDP for metastatic bone pain in breast cancer patients. J Nucl Med 2004;31 Suppl 1:S162.
    • (2004) J Nucl Med , vol.31 SUPPL. 1
    • Lam, M.G.1    De Klerk, J.M.2    Tan, S.3
  • 35
    • 0032868179 scopus 로고    scopus 로고
    • Pain palliation with rhenium-186 HEDP in breast cancer patients with disseminated bone metastases
    • Palmedo H, Bender H, Dierke-Dzierzon C, et al. Pain palliation with rhenium-186 HEDP in breast cancer patients with disseminated bone metastases. Clin Nucl Med 1999; 24:643.
    • (1999) Clin Nucl Med , vol.24 , pp. 643
    • Palmedo, H.1    Bender, H.2    Dierke-Dzierzon, C.3
  • 36
    • 33846517615 scopus 로고    scopus 로고
    • [186Re]HEDP in the palliation of painful bone metastases from cancers other than prostate and breast
    • Minutoli F, Herberg A, Spadaro P, et al. [186Re]HEDP in the palliation of painful bone metastases from cancers other than prostate and breast. Q J Nucl Med Mol Imaging 2006; 50:355.
    • (2006) Q J Nucl Med Mol Imaging , vol.50 , pp. 355
    • Minutoli, F.1    Herberg, A.2    Spadaro, P.3
  • 37
    • 8444244824 scopus 로고    scopus 로고
    • Palliative treatment of painful disseminated bone metastases with 186Rhenium-HEDP in patients with lung cancer
    • Leondi AH, Souvatzoglou MA, Rapti AS, et al. Palliative treatment of painful disseminated bone metastases with 186Rhenium-HEDP in patients with lung cancer. Q J Nucl Med Mol Imaging 2004;48:211.
    • (2004) Q J Nucl Med Mol Imaging , vol.48 , pp. 211
    • Leondi, A.H.1    Souvatzoglou, M.A.2    Rapti, A.S.3
  • 38
    • 0042887586 scopus 로고    scopus 로고
    • Repeated bone-targeted therapy for hormone-refractory prostate carcinoma: Randomized phase II trial with the new, high-energy radiopharmaceutical rhenium-188 hydroxyethylidenediphosphonate
    • Palmedo M, Manka-Waluch A, Albers P, et al. Repeated bone-targeted therapy for hormone-refractory prostate carcinoma: Randomized phase II trial with the new, high-energy radiopharmaceutical rhenium-188 hydroxyethylidenediphosphonate. J Clin Oncol 2003;21:2869.
    • (2003) J Clin Oncol , vol.21 , pp. 2869
    • Palmedo, M.1    Manka-Waluch, A.2    Albers, P.3
  • 39
    • 0026750068 scopus 로고
    • Samarium- 153-EDTMP: Pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastastic bone cancer
    • Furhanghi M, Holmes RA, Volkert WA, et al. Samarium- 153-EDTMP: Pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastastic bone cancer. J Nucl Med 1992;33:1451.
    • (1992) J Nucl Med , vol.33 , pp. 1451
    • Furhanghi, M.1    Holmes, R.A.2    Volkert, W.A.3
  • 40
    • 0027253922 scopus 로고
    • Samarium-153-EDTMP biodistribution and dosimetry estimation
    • Eary JF, Collins C, Stabin M, et al. Samarium-153-EDTMP biodistribution and dosimetry estimation. J Nucl Med 1993; 34:1031.
    • (1993) J Nucl Med , vol.34 , pp. 1031
    • Eary, J.F.1    Collins, C.2    Stabin, M.3
  • 41
    • 0027958545 scopus 로고
    • Dosimetry and toxicity of samarium-153-EDTMP administered for bone pain due to skeletal metastases
    • Bayouth JE, Macey DJ, Kase LP, et al. Dosimetry and toxicity of samarium-153-EDTMP administered for bone pain due to skeletal metastases. J Nucl Med 1994;35:63.
    • (1994) J Nucl Med , vol.35 , pp. 63
    • Bayouth, J.E.1    Macey, D.J.2    Kase, L.P.3
  • 42
    • 0027521907 scopus 로고
    • Samarium-153- EDTMP in bone metastases of hormone refractory prostate carcinoma: A phase I/II trial
    • Collins C, Eary JF, Donaldson G, et al. Samarium-153- EDTMP in bone metastases of hormone refractory prostate carcinoma: A phase I/II trial. J Nucl Med 1993;34:1839.
    • (1993) J Nucl Med , vol.34 , pp. 1839
    • Collins, C.1    Eary, J.F.2    Donaldson, G.3
  • 43
    • 0024803298 scopus 로고
    • A phase i study of samarium-153 ethylenediaminetetramethylene phosphonate therapy for disseminated skeletal metastases
    • Turner JH, Claringbold PG, Hetherington EL, et al. A phase I study of samarium-153 ethylenediaminetetramethylene phosphonate therapy for disseminated skeletal metastases. J Clin Oncol 1989;7:1926.
    • (1989) J Clin Oncol , vol.7 , pp. 1926
    • Turner, J.H.1    Claringbold, P.G.2    Hetherington, E.L.3
  • 44
    • 0031954325 scopus 로고    scopus 로고
    • Palliation of pain associated with metastatic bone cancer using samarium-153 lexidronam: A double-blind placebo-controlled clinical trial
    • Serafini AN, Houston SJ, Resche I, et al. Palliation of pain associated with metastatic bone cancer using samarium-153 lexidronam: A double-blind placebo-controlled clinical trial. J Clin Oncol 1998;16:1574.
    • (1998) J Clin Oncol , vol.16 , pp. 1574
    • Serafini, A.N.1    Houston, S.J.2    Resche, I.3
  • 45
    • 2342509633 scopus 로고    scopus 로고
    • Samarium-153-Lexidronam complex for treatment complex for treatment of painful bone metatastases in hormone-refractory prostate cancer
    • Sartor O, Reid RH, Hoskin PJ, et al. Samarium-153-Lexidronam complex for treatment complex for treatment of painful bone metatastases in hormone-refractory prostate cancer. Urology 2004;63:940.
    • (2004) Urology , vol.63 , pp. 940
    • Sartor, O.1    Reid, R.H.2    Hoskin, P.J.3
  • 46
    • 0033061339 scopus 로고    scopus 로고
    • Multicentre trial on the efficacy and toxicity of single-dose samarium-153-ethylene diamine tetramethylene phosphonate as a palliative treatment for painful skeletal metastases in China
    • Tian JH, Zhang JM, Hou QT, et al. Multicentre trial on the efficacy and toxicity of single-dose samarium-153-ethylene diamine tetramethylene phosphonate as a palliative treatment for painful skeletal metastases in China. Eur J Nucl Med 1999;26:2.
    • (1999) Eur J Nucl Med , vol.26 , pp. 2
    • Tian, J.H.1    Zhang, J.M.2    Hou, Q.T.3
  • 47
    • 66349089867 scopus 로고    scopus 로고
    • Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer
    • Fizazi K, Beuzeboc P, Lumbroso J, et al. Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer. J Clin Oncol 2009;27:2429.
    • (2009) J Clin Oncol , vol.27 , pp. 2429
    • Fizazi, K.1    Beuzeboc, P.2    Lumbroso, J.3
  • 48
    • 84890473067 scopus 로고    scopus 로고
    • Optimal timing of bisphosphonate administration in combination with samarium-153 oxabifore in the treatment of painful metastatic bone disease
    • Rasulova N, Lyubshin V, Arybzhanov D, et al. Optimal timing of bisphosphonate administration in combination with samarium-153 oxabifore in the treatment of painful metastatic bone disease. World J Nucl Med 2013;12:14.
    • (2013) World J Nucl Med , vol.12 , pp. 14
    • Rasulova, N.1    Lyubshin, V.2    Arybzhanov, D.3
  • 49
    • 33744945763 scopus 로고    scopus 로고
    • Combined therapy of Sr-89 and zoledronic acid in patients with painful bone metastases
    • Storto G, Klain M, Paone G, et al. Combined therapy of Sr-89 and zoledronic acid in patients with painful bone metastases. Bone 2006;39:35.
    • (2006) Bone , vol.39 , pp. 35
    • Storto, G.1    Klain, M.2    Paone, G.3
  • 50
    • 45049087273 scopus 로고    scopus 로고
    • Treatment efficacy of combined biphosphonates and 186Re-HEDP treatment in cancer patients with bone metastases
    • Koutsikos J, Leondi A. Treatment efficacy of combined biphosphonates and 186Re-HEDP treatment in cancer patients with bone metastases. Eur J Nucl Med Mol Imaging 2008; 35:1392.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 1392
    • Koutsikos, J.1    Leondi, A.2
  • 51
    • 0036100542 scopus 로고    scopus 로고
    • Lack of effect of a bisphosphonate (pamidronate disodium) infusion on subsequent skeletal uptake of Sm-153 EDTMP
    • Marcus CS, Saeed S, Mlikotic A, et al. Lack of effect of a bisphosphonate (pamidronate disodium) infusion on subsequent skeletal uptake of Sm-153 EDTMP. Clin Nucl Med 2002;27:427.
    • (2002) Clin Nucl Med , vol.27 , pp. 427
    • Marcus, C.S.1    Saeed, S.2    Mlikotic, A.3
  • 52
    • 40949146185 scopus 로고    scopus 로고
    • Combined use of zoledronic acid and 153Sm-EDTMP in hormone-refractory prostate cancer patients with bone metastases
    • Lam MG, Dahmane A, Stevens WH, et al. Combined use of zoledronic acid and 153Sm-EDTMP in hormone-refractory prostate cancer patients with bone metastases. Eur J Nucl Med Mol Imaging 2008;35:756.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 756
    • Lam, M.G.1    Dahmane, A.2    Stevens, W.H.3
  • 53
    • 34247636849 scopus 로고    scopus 로고
    • 89Sr versus 153Sm-EDTMP: Comparison of treatment efficacy of painful bone metastases in prostate and breast carcinoma
    • Baczyk M, Czepczynski R, Milecki P, et al. 89Sr versus 153Sm-EDTMP: Comparison of treatment efficacy of painful bone metastases in prostate and breast carcinoma. Nucl Med Commun 2007;28:245.
    • (2007) Nucl Med Commun , vol.28 , pp. 245
    • Baczyk, M.1    Czepczynski, R.2    Milecki, P.3
  • 54
    • 0035004901 scopus 로고    scopus 로고
    • Metastatic bone pain palliation with 89-Sr and 186-Re-HEDP in breast cancer patients
    • Sciuto R, Festa A. Pasqualoni R, et al. Metastatic bone pain palliation with 89-Sr and 186-Re-HEDP in breast cancer patients. Breast Cancer Res Treat 2001;66:101.
    • (2001) Breast Cancer Res Treat , vol.66 , pp. 101
    • Sciuto, R.1    Festa, A.2    Pasqualoni, R.3
  • 55
    • 34447545672 scopus 로고    scopus 로고
    • A comparative study of 188Re-HEDP, 186Re-HEDP, 153Sm-EDTMP and 89Sr in the treatment of painful skeletal metastases
    • Liepe K, Kotzerke J. A comparative study of 188Re-HEDP, 186Re-HEDP, 153Sm-EDTMP and 89Sr in the treatment of painful skeletal metastases. Nucl Med Commun 2007; 28:623.
    • (2007) Nucl Med Commun , vol.28 , pp. 623
    • Liepe, K.1    Kotzerke, J.2
  • 56
    • 0036606104 scopus 로고    scopus 로고
    • Significant antitumor effect from bone-seeking, a-particle-emitting 223Ra demonstrated in an experimental skeletal metastases model
    • Henriksen G, Breistol K, Bruland OS, et al. Significant antitumor effect from bone-seeking, a-particle-emitting 223Ra demonstrated in an experimental skeletal metastases model. Cancer Res 2002;62:3120.
    • (2002) Cancer Res , vol.62 , pp. 3120
    • Henriksen, G.1    Breistol, K.2    Bruland, O.S.3
  • 57
    • 84859476468 scopus 로고    scopus 로고
    • The role of bone-seeking radionuclides in the palliative treatment of patients with painful osteoblastic skeletal metastases
    • Tomblyn M. The role of bone-seeking radionuclides in the palliative treatment of patients with painful osteoblastic skeletal metastases. Cancer Control 2012;19:137.
    • (2012) Cancer Control , vol.19 , pp. 137
    • Tomblyn, M.1
  • 58
    • 0032735824 scopus 로고    scopus 로고
    • Alpha particle doses to cells of the bone remodeling cycle from alpha-particle-emitting bone-seekers: Indications of an antiresorptive effect of actinides
    • Salmon PL, Onischuk YN, Bondarenko OA, et al. Alpha particle doses to cells of the bone remodeling cycle from alpha-particle-emitting bone-seekers: Indications of an antiresorptive effect of actinides. Radiat Res 1999;152:S43.
    • (1999) Radiat Res , vol.152
    • Salmon, P.L.1    Onischuk, Y.N.2    Bondarenko, O.A.3
  • 59
    • 33746707858 scopus 로고    scopus 로고
    • High-linear energy transfer irradiation targeted to skeletal metastases by the alpha-emitter 223Ra: Adjuvant or alternative to conventional modalities?
    • Bruland OS, Nilsson S, Fisher DR, et al. high-linear energy transfer irradiation targeted to skeletal metastases by the alpha-emitter 223Ra: Adjuvant or alternative to conventional modalities?. Clin Cancer Res 2006;12(20 pt 2):6250s.
    • (2006) Clin Cancer Res , vol.12 PART. 2 , Issue.20
    • Bruland, O.S.1    Nilsson, S.2    Fisher, D.R.3
  • 60
    • 84874106208 scopus 로고    scopus 로고
    • Dosimetry of 223Ra-chloride: Dose to normal organs and tissues
    • Lassmann M, Nosske D. Dosimetry of 223Ra-chloride: Dose to normal organs and tissues. Eur J Nucl Med Mol Imaging 2013;40:207.
    • (2013) Eur J Nucl Med Mol Imaging , vol.40 , pp. 207
    • Lassmann, M.1    Nosske, D.2
  • 61
    • 20644447798 scopus 로고    scopus 로고
    • First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases
    • Nilsson S, Larsen RH, Fossa SD, et al. First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases. Clin Cancer Res 2005;11:4451.
    • (2005) Clin Cancer Res , vol.11 , pp. 4451
    • Nilsson, S.1    Larsen, R.H.2    Fossa, S.D.3
  • 62
    • 34347244905 scopus 로고    scopus 로고
    • Bone-targeted radium- 223 in symptomatic, hormone-refractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study
    • Nilsson S, Franzen L, Parker C, et al. Bone-targeted radium- 223 in symptomatic, hormone-refractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study. Lancet Oncol 2007;8:587.
    • (2007) Lancet Oncol , vol.8 , pp. 587
    • Nilsson, S.1    Franzen, L.2    Parker, C.3
  • 63
    • 84874543674 scopus 로고    scopus 로고
    • Two-year survival follow-up of the randomized, double-blind, placebo-controlled phase II study of radium-223 chloride in patients with castration-resistant prostate cancer and bone metastases
    • Nilsson S, Franzen L, Parker C, et al. Two-year survival follow-up of the randomized, double-blind, placebo-controlled phase II study of radium-223 chloride in patients with castration-resistant prostate cancer and bone metastases. Clin Genitourin Cancer 2013;11:20.
    • (2013) Clin Genitourin Cancer , vol.11 , pp. 20
    • Nilsson, S.1    Franzen, L.2    Parker, C.3
  • 64
    • 84871926771 scopus 로고    scopus 로고
    • A randomized, double-blind, dose-finding, multicenter, phase 2 study of radium chloride (Ra 223) in patients with bone metastases and castration-resistant prostate cancer
    • Parker CC, Pascoe S, Chodacki A, et al. A randomized, double-blind, dose-finding, multicenter, phase 2 study of radium chloride (Ra 223) in patients with bone metastases and castration-resistant prostate cancer. Eur Urol 2013; 63:189.
    • (2013) Eur Urol , vol.63 , pp. 189
    • Parker, C.C.1    Pascoe, S.2    Chodacki, A.3
  • 65
    • 84865834363 scopus 로고    scopus 로고
    • Overall survival benefit of radium-223 chloride in the treatment of patients with symptomatic bone metastases in castration resistant prostate cancer: A phase III randomized trial (ALSYMPCA)
    • (abstract 8)
    • Parker C, Heinrich D, O'Sullivan JM, et al. Overall survival benefit of radium-223 chloride in the treatment of patients with symptomatic bone metastases in castration resistant prostate cancer: A phase III randomized trial (ALSYMPCA). J Clin Oncol 2012;30 (abstract 8).
    • (2012) J Clin Oncol , vol.30
    • Parker, C.1    Heinrich, D.2    O'sullivan, J.M.3
  • 66
    • 84880428467 scopus 로고    scopus 로고
    • Alpha emitter radium- 223 and survival in metastatic prostate cancer
    • Parker C, Nilsson S, Heinrich D, et al. Alpha emitter radium- 223 and survival in metastatic prostate cancer. N Engl J Med 2013;369:213.
    • (2013) N Engl J Med , vol.369 , pp. 213
    • Parker, C.1    Nilsson, S.2    Heinrich, D.3
  • 67
    • 84872507131 scopus 로고    scopus 로고
    • Radium-223 chloride: A potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease
    • Harrison MR, Wong TZ, Armstrong AJ, et al. Radium-223 chloride: A potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease. Cancer Manag Res 2013;5:1.
    • (2013) Cancer Manag Res , vol.5 , pp. 1
    • Harrison, M.R.1    Wong, T.Z.2    Armstrong, A.J.3
  • 68
    • 80755169727 scopus 로고    scopus 로고
    • Radionuclide therapy and integrated protocols for bone metastases
    • Chiacchio S, Mazzarri S, Lorenzoni A, et al. Radionuclide therapy and integrated protocols for bone metastases. Q J Nucl Med Mol Imaging 2011;55:431.
    • (2011) Q J Nucl Med Mol Imaging , vol.55 , pp. 431
    • Chiacchio, S.1    Mazzarri, S.2    Lorenzoni, A.3
  • 69
    • 80755171312 scopus 로고    scopus 로고
    • The Vienna protocol and perspectives in radionuclide therapy
    • Sinzinger H, Palumbo B, Ozker K, et al. The Vienna protocol and perspectives in radionuclide therapy. Q J Nucl Med Mol Imaging 2011;55:420.
    • (2011) Q J Nucl Med Mol Imaging , vol.55 , pp. 420
    • Sinzinger, H.1    Palumbo, B.2    Ozker, K.3
  • 70
    • 34250368094 scopus 로고    scopus 로고
    • Clinical benefit of bone-targeted radiometabolic therapy with 153Sm-EDTMP combined with chemotherapy in patients with metastatic hormone-refractory prostate cancer
    • Ricci S, Boni G, Pastina I, et al. Clinical benefit of bone-targeted radiometabolic therapy with 153Sm-EDTMP combined with chemotherapy in patients with metastatic hormone-refractory prostate cancer. Eur J Nucl Med Mol Imaging 2007;34:1023.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 1023
    • Ricci, S.1    Boni, G.2    Pastina, I.3
  • 71
    • 80755171322 scopus 로고    scopus 로고
    • Pathophysiological premises to radiotracers for bone metastases
    • Cuccurullo V, Cascini GL, Rossi A, et al. Pathophysiological premises to radiotracers for bone metastases. Q J Nucl Med Mol Imaging 2011;55:420.
    • (2011) Q J Nucl Med Mol Imaging , vol.55 , pp. 420
    • Cuccurullo, V.1    Cascini, G.L.2    Rossi, A.3
  • 72
    • 80054821668 scopus 로고    scopus 로고
    • Theranostics: Combining imaging and therapy
    • Kelkar SS, Reineke TM. Theranostics: Combining imaging and therapy. Bioconjug Chem 2011;22:1879.
    • (2011) Bioconjug Chem , vol.22 , pp. 1879
    • Kelkar, S.S.1    Reineke, T.M.2
  • 73
    • 83755225132 scopus 로고    scopus 로고
    • Radiopeptide imaging and therapy in Europe
    • Ambrosini V, Fanti M, Fanti S, et al. Radiopeptide imaging and therapy in Europe. J Nucl Med 2011;52 Suppl 2:42S.
    • (2011) J Nucl Med , vol.52 SUPPL. 2
    • Ambrosini, V.1    Fanti, M.2    Fanti, S.3
  • 74
    • 84859335863 scopus 로고    scopus 로고
    • Concepts, consequences and implications of theranosis
    • De Nardo GL, De Nardo SJ. Concepts, consequences and implications of theranosis. Semin Nucl Med 2012;42:147.
    • (2012) Semin Nucl Med , vol.42 , pp. 147
    • De Nardo, G.L.1    De Nardo, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.