Effect of adalimumab on sleep parameters in patients with psoriasis and obstructive sleep apnea: A randomized controlled trial

Journal of Dermatological Treatment

Volumn 25, Issue 1, 2014, Pages 57-60

  Maari, Catherine ^a   Bolduc, Chantal ^a   Nigen, Simon ^a   Marchessault, Philippe ^a   Bissonnette, Robert ^a  

^a INNOVADERM RESEARCH   (Canada)

Author keywords

Anti TNF ; Clinical trial; Phase IV; Polysomnography; Sleepiness

Indexed keywords

ADALIMUMAB; PLACEBO;

ADULT; AGED; APNEA HYPOPNEA INDEX; ARTICLE; BODY SURFACE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DEMYELINATING DISEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; LOADING DRUG DOSE; MALE; MULTICENTER STUDY; OPPORTUNISTIC INFECTION; PHASE 4 CLINICAL TRIAL; POLYSOMNOGRAPHY; PRIORITY JOURNAL; PSORIASIS VULGARIS; RANDOMIZED CONTROLLED TRIAL; SLEEP DISORDERED BREATHING; SLEEP PARAMETERS; SYMPTOM; TREATMENT DURATION; TREATMENT OUTCOME; TUBERCULOSIS;

ADULT; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL, HUMANIZED; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; PSORIASIS; SLEEP APNEA, OBSTRUCTIVE; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890512900     PISSN: 09546634     EISSN: 14711753     Source Type: Journal    
DOI: 10.3109/09546634.2012.713458     Document Type: Article

References (18)

1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328:1230-1235.
2. Ludka O, Konecny T, Somers V. Sleep apnea, cardiac arrhythmias, and sudden death. Tex Heart Inst J. 2011;38:340-343.
3. Vgontzas AN, Papanicolaou DA, Bixler EO, Kales A, Tyson K, Chrousos GP. Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity. J Clin Endocrinol Metab. 1997;82:1313-1316.
4. Vagiakis E, Kapsimalis F, Lagogianni I, et al. Gender differences on polysomnographic findings in Greek subjects with obstructive sleep apnea syndrome. Sleep Med. 2006;7:424-430.
5. Weaver TE, Laizner AM, Evans LK, et al. An instrument to measure functional status outcomes for disorders of excessive sleepiness. Sleep. 1997;20:835-843.
6. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14:540-545.
7. Fredriksson T, Pettersson U. Severe psoriasis-oral therapy with a new retinoid. Dermatologica. 1978;157:238-244.
8. Martinez D, Klein C, Rahmeier L, et al. Sleep apnea is a stronger predictor for coronary heart disease than traditional risk factors. Sleep Breath. 2011 [Epub ahead of print].
9. Kim N, Thrash B, Menter A. Comorbidities in psoriasis patients. Semin Cutan Med Surg. 2010;29:10-15.
10. Lam JC, Mak JC, Ip MS. Obesity, obstructive sleep apnea and metabolic syndrome. Respirology. 2010;17:223-236.
11. Henseler T, Christophers E. Disease concomitance in psoriasis. J Am Acad Dermatol. 1995;32:982-986.
12. Sterry W, Strober BE, Menter A. Obesity in psoriasis: the metabolic, clinical and therapeutic implications. Report of an interdisciplinary conference and review. Br J Dermatol. 2007;157:649-655.
13. Buslau M, Benotmane K. Cardiovascular complications of psoriasis: does obstructive sleep apnoea play a role? Acta Derm Venereol. 1999; 79:234.
14. Gowda S, Goldblum OM, McCall WV, Feldman SR. Factors affecting sleep quality in patients with psoriasis. J Am Acad Dermatol. 2010;63: 114-123.
15. Vgontzas AN, Zoumakis E, Lin HM, Bixler EO, Trakada G, Chrousos GP. Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist. J Clin Endocrinol Metab. 2004;89:4409-4413.
16. Menter A, Tyring SK, Gordon K, et al. Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial. J Am Acad Dermatol. 2008;58:106-115.
17. Kimball A, Gu Y, Okun M, Jemec G. Efficacy and safety of adalimumab in treatment of moderate to severe hidradenitis suppurativa: Results From the Placebo-controlled Portion of a Phase II, Randomized, Double-Blind Study [abstract P3340]. E-poster session presented at the 69th American Academy of Dermatology Annual Meeting; 4-8 Feb 2011; New Orleans.
18. Sharma SK, Agrawal S, Damodaran D, et al. CPAP for the metabolic syndrome in patients with obstructive sleep apnea. N Engl J Med. 2011; 365:2277-2286.