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Volumn 31, Issue 19, 2013, Pages

Major clinical response to a BRAF inhibitor in a patient with a BRAF L597R-mutated melanoma

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DABRAFENIB; DACARBAZINE; IMATINIB; LAPATINIB; MITOGEN ACTIVATED PROTEIN KINASE; SORAFENIB; STEM CELL FACTOR; VEMURAFENIB; ANTINEOPLASTIC AGENT; ARGININE; BRAF PROTEIN, HUMAN; CARBANILAMIDE DERIVATIVE; DRUG DERIVATIVE; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; LEUCINE; NICOTINAMIDE; OXIME; SULFONAMIDE;

EID: 84890512515     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2012.46.1061;     Document Type: Article
Times cited : (46)

References (5)
  • 1
    • 77949354563 scopus 로고    scopus 로고
    • PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells
    • Halaban R, Zhang W, Bacchiocchi A, et al: PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. Pigment Cell Melanoma Res 23:190-200, 2010
    • (2010) Pigment Cell Melanoma Res , vol.23 , pp. 190-200
    • Halaban, R.1    Zhang, W.2    Bacchiocchi, A.3
  • 2
    • 84866342282 scopus 로고    scopus 로고
    • BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors
    • Dahlman KB, Xia J, Hutchinson K, et al: BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors. Cancer Discov 2:791-797, 2012
    • (2012) Cancer Discov , vol.2 , pp. 791-797
    • Dahlman, K.B.1    Xia, J.2    Hutchinson, K.3
  • 4
    • 12144289677 scopus 로고    scopus 로고
    • Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
    • Wan PT, Garnett MJ, Roe SM, et al: Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 116:855-867, 2004
    • (2004) Cell , vol.116 , pp. 855-867
    • Wan, P.T.1    Garnett, M.J.2    Roe, S.M.3
  • 5
    • 84857232726 scopus 로고    scopus 로고
    • Analytical performance of a real-time PCR-based assay for V600 mutations in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma
    • Halait H, Demartin K, Shah S, et al: Analytical performance of a real-time PCR-based assay for V600 mutations in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma. Diagn Mol Pathol 21:1-8, 2012
    • (2012) Diagn Mol Pathol , vol.21 , pp. 1-8
    • Halait, H.1    Demartin, K.2    Shah, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.