Study of antidepressant-like activity of an enriched phloroglucinol fraction obtained from Hypericum caprifoliatum

Pharmaceutical Biology

Volumn 52, Issue 1, 2014, Pages 105-110

  Centurião, Fernanda B ^a   Braga, Andressa ^a   Machado, Fernanda Rossatto ^a   Tagliari, Barbara ^a   Müller, Liz G ^a   Kolling, Janaína ^a   Von Poser, Gilsane ^a   Wyse, Angela T S ^a   Rates, Stela M K ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Depression; Forced swimming stress; K+ ATPase; Na+; Na+ channels

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM); CEVADINE; PHLOROGLUCINOL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; EX VIVO STUDY; FORCED SWIM TEST; HIPPOCAMPUS; HYPERICUM; HYPERICUM CAPRIFOLIATUM; IMMOBILIZATION; LOCOMOTION; MALE; MOUSE; NONHUMAN;

ANIMALS; ANTIDEPRESSIVE AGENTS; CEREBRAL CORTEX; DEPRESSION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HYPERICUM; MALE; MICE; PHLOROGLUCINOL; PLANT EXTRACTS; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; SWIMMING; VERATRINE;

EID: 84890498045     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.816970     Document Type: Article

References (35)

1. Bradford MM. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein- dye binding. Anal Biochem 72:248-54
2. Brasil. (2008). Ministério Público. Lei no. 11.794, de 8 de outubro de 2008. Published in DOU 9.10.2008
3. Council for International Organizations of Medical Sciences. International Guiding Principles for Biomedical Research Involving Animals. Geneva: CIOMS; 1985
4. Crema L, Schlabitz M, Tagliari B, et al. (2010). Na+, K+ ATPase activity is reduced in amygdala of rats with chronic stress-induced anxiety-like behavior. Neurochem Res 35:1787-95
5. Dall'Agnol R, Ferraz A, Bernardi AP, et al. (2003). Antimicrobial activity of some Hypericum species. Phytomedicine 10:511-16
6. Daudt R, von Poser GL, Neves G, Rates SM. (2000). Screening for the antidepressant activity of some species of Hypericum from South Brazil. Phytother Res 14:344-6
7. de Vasconcellos AP, Zugno AI, dos Santos AH, et al. (2005). Na+, K+- ATPase activity is reduced in hippocampus of rats submitted to an experimental model of depression: Effect of chronic lithium treatment and possible involvement in learning deficits. Neurobiol Learn Mem 84:102-10
8. El-Mallakh RS, Elmaadawi AZ, Loganathan M, et al. (2010). Bipolar disorder: An update. Postgrad Med 122:24-31
9. Ferraz A, Bordignon S, Mans D, et al. (2002). Screening for the presence of hypericins in southern Brazilian species of Hypericum (Guttiferae). Pharm Biol 40:294-7
10. Gamaro GD, Streck EL, Matté C, et al. (2003). Reduction of hippocampal Na+, K+-ATPase activity in rats subjected to an experimental model of depression. Neurochem Res 28:1339-44
11. Goto A, Yamada K, Nagoshi H, et al. (1995). Stress-induced elevation of ouabain-like compound in rat plasma and adrenal. Hypertension 26: 1173-6
12. Grisar T. (1984). Glial and neuronal Na+-K+ pump in epilepsy. Ann Neurol 16:S128-34
13. Herman L, Hougland T, El-Mallakh RS. (2007). Mimicking human bipolar ion dysregulation models mania in rats. Neurosci Biobehav Rev 31:874-81
14. Inoue N, Matsui H. (1990). Activation of a brain type Na pump after glutamate excitation of cerebral neurons. Brain Res 534:309-12
15. Kristensen AS, Andersen J, Jøgersen TN, et al. (2011). SLC6 neurotransmitter transporters: Structure, function, and regulation. Pharmacol Rev 63:585-640
16. Lenkey N, Karoly R, Lukacs P, et al. (2010). Classification of drugs based on properties of sodium channel inhibition: A comparative automated patch-clamp study. PLoS One 5:e15568. doi: 10.1371/ journal.pone.0015568
17. Li R, El-Mallakh RS. (2004). Differential response of bipolar and normal control lymphoblastoid cell sodium pump to ethacrynic acid. J Affect Disord 80:11-17
18. Linde K, Schumann I, Meissner K, et al. (2011). Treatment of depressive disorders in primary care-protocol of a multiple treatment systematic review of randomized controlled trials. BMC Fam Pract 12:127-33
19. Looney SW, El-Mallakh RS. (1997). Meta-analysis of erythrocyte Na, KATPase activity in bipolar illness. Depress Anxiety 5:53-65
20. McEwen BS. (2001). Plasticity of the hippocampus: Adaptation to chronic stress and allostatic load. Ann N Y Acad Sci 933:265-77
21. Müller LG, Salles LA, Stein AC, et al. (2012). Antidepressant-like effect of Valeriana glechomifolia Meyer (Valerianaceae) in mice. Prog Neuropsychopharmacol Biol Psychiatry 36:101-9
22. Nör C, Albring D, Ferraz ABF, et al. (2004). Phloroglucinol derivatives from our Hypericum species belonging to the Trigynobrathys section. Biochem Syst Ecol 32:517-19
23. Pancrazio JJ, Kamatchi GL, Roscoe AK, Lynch 3rd C. (1998). Inhibition of neuronal Na+ channels by antidepressant drugs. J Pharmacol Exp Ther 284:208-14
24. Porsolt RD, Anton G, Blavet N, Jalfre M. (1978). Behavioural despair in rats: A new model sensitive to antidepressant treatments. Eur J Pharmacol 47:379-91
25. Prica C, Hascoet M, Bourin M. (2008). Antidepressant-like effect of lamotrigine is reversed by veratrine: A possible role of sodium channels in bipolar depression. Behav Brain Res 191:49-54
26. Rocha L, Marston A, Potterat O, et al. (1995). Antibacterial phloroglucinols and flavonoids of Hypericum brasilience. Phytochemistry 40:1447-52
27. Rudnick G. (1998). Bioenergetics of neurotransmitter transport. J Bioenerg Biomembr 30:173-85
28. Sheline YI, Gado MH, Kraemer HC. (2003). Untreated depression and hippocampal volume loss. Am J Psychiatry 160:1516-18
29. Therien AG, Blostein R. (2000). Mechanisms of sodium pump regulation. Am J Physiol Cell Physiol 279:541-66
30. Viana A, Rates S, Naudin B, et al. (2008). Effects of acute or 3-day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stressinduced increase in serum and brain corticosterone levels. J Psychopharmacol 22:681-90
31. Viana AF, do Rego JC, von Poser G, et al. (2005). The antidepressantlike effect of Hypericum caprifoliatum Cham & Schlecht (Guttiferae) on forced swimming test results from an inhibition of neuronal monoamine uptake. Neuropharmacology 49:1042-52
32. Weidemann H, Salomon N, Avnit-Sagi T, et al. (2004). Diverse effects of stress and additional adrenocorticotropic hormone on digitalis-like compounds in normal and nude mice. J Neuroendocrinol 16:458-63
33. Wonnemann M, Singer A, Mü ller WE. (2000). Inhibition of synaptosomal uptake of 3H-L-glutamate and 3H-GABA by hyperforin, a major constituent of St. John's Wort: The role of amiloride sensitive sodium conductive pathways. Neuropsychopharmacology 23:188-97
34. Wyse AT, Streck EL, Barros SV, et al. (2000). Methylmalonate administration decreases Na+, K+-ATPase activity in cerebral cortex of rats. Neuroreport 11:2331-4
35. Xhaard H, Backström V, Denessiouk K, Johnson MS. (2008). Coordination of Na(+) by monoamine ligands in dopamine, norepinephrine, and serotonin transporters. J Chem Inf Model 48:1423-37