Transcatheter aortic valve implantation using anatomically oriented, marrow stromal cell-based, stented, tissue-engineered heart valves: Technical considerations and implications for translational cell-based heart valve concepts

European Journal of Cardio-thoracic Surgery

Volumn 45, Issue 1, 2014, Pages 61-68

  Emmert, Maximilian Y ^a,b   Weber, Benedikt ^a,b   Behr, Luc ^c   Sammut, Sebastien ^c   Frauenfelder, Thomas ^b   Wolint, Petra ^a,b   Scherman, Jacques ^b   Bettex, Dominique ^d   Grünenfelder, Jürg ^b   Falk, Volkmar ^b   Hoerstrup, Simon P ^a,b  

^a Swiss Center for Regenerative Medicine   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c INSTITUT MUTUALISTE MONTSOURIS   (France)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Aortic valve; Marrow stromal cells; Tavi; Tissue engineered heart valvesm; Transapical; Transcatheter

Indexed keywords

ADULT; ANGIOGRAPHY; ANIMAL EXPERIMENT; AORTA VALVE; AORTA VALVE PROLAPSE; AORTA VALVE REGURGITATION; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW CELL; BONE MARROW MONONUCLEAR CELL; CELL ISOLATION; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY OBSTRUCTION; ECHOCARDIOGRAPHY; FLUOROSCOPY; HEART VALVE PROSTHESIS; IN VITRO STUDY; NITINOL STENT; NONHUMAN; PARAVALVULAR LEAKAGE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SELF EXPANDING STENT; SYSTEMIC CIRCULATION; TISSUE ENGINEERED HEART VALVE; TISSUE ENGINEERING; TRANSCATHETER AORTIC VALVE IMPLANTATION; VALVE DELIVERY CATHETER;

AORTIC VALVE; MARROW STROMAL CELLS; TAVI; TISSUE-ENGINEERED HEART VALVES; TRANSAPICAL; TRANSCATHETER;

ANIMALS; BLOOD VESSEL PROSTHESIS; HEART VALVE PROSTHESIS; HEART VALVE PROSTHESIS IMPLANTATION; HEART VALVES; MESENCHYMAL STROMAL CELLS; PROSTHESIS DESIGN; SHEEP; TISSUE SCAFFOLDS;

EID: 84890489313     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1093/ejcts/ezt243     Document Type: Article

References (25)

1. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG et al. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 2010;363:1597-607.
2. Falk V, Walther T, Schwammenthal E, Strauch J, Aicher D, Wahlers T et al. Transapical aortic valve implantation with a self-expanding anatomically oriented valve. Eur Heart J 2011;32:878-87.
3. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med 2011;364:2187-98.
4. Walther T, Schuler G, Borger MA, Kempfert J, Seeburger J, Ruckert Y et al. Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity-matched conventional aortic valve replacement. Eur Heart J 2010;31:1398-403.
5. Kempfert J, Rastan AJ, Mohr FW, Walther T. A new self-expanding transcatheter aortic valve for transapical implantation-first in man implantation of the JenaValve. Eur J Cardiothorac Surg 2011;40:761-3.
6. Treede H, Mohr FW, Baldus S, Rastan A, Ensminger S, Arnold M et al. Transapical transcatheter aortic valve implantation using the JenaValve system: acute and 30-day results of the multicentre CE-mark study. Eur J Cardiothorac Surg 2012;41:e131-8.
7. Sundermann SH, Grunenfelder J, Corti R, Rastan AJ, Linke A, Lange R et al. Feasibility of the Engager aortic transcatheter valve system using a flexible over-the-wire design. Eur J Cardiothorac Surg 2012;42:e48-52.
8. Kempfert J, Rastan AJ, Beyersdorf F, Schonburg M, Schuler G, Sorg S et al. Trans-apical aortic valve implantation using a new self-expandable bioprosthesis: initial outcomes. Eur J Cardiothorac Surg 2011;40:1114-9.
9. Kempfert J, Treede H, Rastan AJ, Schonburg M, Thielmann M, Sorg S et al. Transapical aortic valve implantation using a new self-expandable bioprosthesis (ACURATE TA): 6-month outcomes. Eur J Cardiothorac Surg 2013;43:52-7.
10. Falk V, Schwammenthal EE, Kempfert J, Linke A, Schuler G, Mohr FW et al. New anatomically oriented transapical aortic valve implantation. Ann Thorac Surg 2009;87:925-6.
11. Kiefer P, Gruenwald F, Kempfert J, Aupperle H, Seeburger J, Mohr FW et al. Crimping may affect the durability of transcatheter valves: an experimental analysis. Ann Thorac Surg 2011;92:155-60.
12. Emmert MY, Weber B, Behr L, Frauenfelder T, Brokopp CE, Grunenfelder J et al. Transapical aortic implantation of autologous marrow stromal cellbased tissue-engineered heart valves: first experiences in the systemic circulation. JACC Cardiovasc Interv 2011;4:822-3.
13. Emmert MY, Weber B, Wolint P, Behr L, Sammut S, Frauenfelder T et al. Stem cell-based transcatheter aortic valve implantation: first experiences in a pre-clinical model. JACC Cardiovasc Interv 2012;5:874-83.
14. Weber B, Scherman J, Emmert MY, Gruenenfelder J, Verbeek R, Bracher M et al. Injectable living marrow stromal cell-based autologous tissue engineered heart valves: first experiences with a one-step intervention in primates. Eur Heart J 2011;32:2830-40.
15. Dolgin E. Taking tissue engineering to heart. Nat Med 2011;17:1032-5.
16. Roh JD, Sawh-Martinez R, Brennan MP, Jay SM, Devine L, Rao DA et al. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proc Natl Acad Sci USA 2010;107:4669-74.
17. Shińoka T, Imai Y, Ikada Y. Transplantation of a tissue-engineered pulmonary artery. N Engl J Med 2001;344:532-3.
18. Shińoka T, Matsumura G, Hibino N, Naito Y, Watanabe M, Konuma T et al. Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells. J Thorac Cardiovasc Surg 2005;129:1330-8.
19. Genereux P, Head SJ, Wood DA, Kodali SK, Williams MR, Paradis JM et al. Transcatheter aortic valve implantation: 10-year anniversary part II: clinical implications. Eur Heart J 2012;33:2399-402.
20. Genereux P, Head SJ, Wood DA, Kodali SK, Williams MR, Paradis JM et al. Transcatheter aortic valve implantation 10-year anniversary: review of current evidence and clinical implications. Eur Heart J 2012;33:2388-98.
21. Kappetein AP, Head SJ, Genereux P, Piazza N, van Mieghem NM, Blackstone EH et al. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. J Am Coll Cardiol 2012;60:1438-54.
22. Kappetein AP, Head SJ, Genereux P, Piazza N, van Mieghem NM, Blackstone EH et al. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. Eur J Cardiothorac Surg 2012;42:S45-60.
23. Brennan MP, Dardik A, Hibino N, Roh JD, Nelson GN, Papademitris X et al. Tissue-engineered vascular grafts demonstrate evidence of growth and development when implanted in a juvenile animal model. Ann Surg 2008; 248:370-7.
24. Hibino N, McGillicuddy E, Matsumura G, Ichihara Y, Naito Y, Breuer C et al. Late-term results of tissue-engineered vascular grafts in humans. J Thorac Cardiovasc Surg 2010;139:431-6.
25. Schmidt D, Dijkman PE, Driessen-Mol A, Stenger R, Mariani C, Puolakka A et al. Minimally-invasive implantation of living tissue engineered heart valves: a comprehensive approach from autologous vascular cells to stem cells. J Am Coll Cardiol 2010;56:510-20.