A novel strategy for preserving renal grafts in an ex vivo setting: Potential for enhancing the marginal donor pool

FASEB Journal

Volumn 27, Issue 12, 2013, Pages 4822-4833

  Zhao, Hailin ^a   Ning, Jiaolin ^a,b   Savage, Sinead ^a   Kang, Heechan ^a   Lu, Kaizhi ^b   Zheng, Xia ^a   George, Andrew J T ^a   Ma, Daqing ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Ischemic injury; Organ preservation; Organ transplantation; Renoprotection; Xenon

Indexed keywords

APOPTOSIS INDUCING FACTOR; CYTOCHROME C; HEAT SHOCK PROTEIN 70; HIGH MOBILITY GROUP B1 PROTEIN; NITROGEN; PROTEIN BCL 2; XENON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; EX VIVO STUDY; HUMAN; HUMAN CELL; KIDNEY CORTEX; KIDNEY GRAFT; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; MALE; MITOCHONDRION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RENAL PROTECTION;

ISCHEMIC INJURY; ORGAN PRESERVATION; ORGAN TRANSPLANTATION; RENOPROTECTION; XENON;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CELL LINE; CYTOCHROMES C; HSP70 HEAT-SHOCK PROTEINS; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; ORGAN PRESERVATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, INBRED LEW; XENON;

EID: 84890457192     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-236810     Document Type: Article

References (43)

1. Moers, C., Leuvenink, H. G., and Ploeg, R. J. (2010) Donation after cardiac death: evaluation of revisiting an important donor source. Nephrol. Dial. Transplant. 25, 666-673
2. Aydin, Z., van Zonneveld, A. J., de Fijter, J. W., and Rabelink, T. J. (2007) New horizons in prevention and treatment of ischaemic injury to kidney transplants. Nephrol. Dial. Transplant. 22, 342-346
3. Pratschke, J., Tullius, S. G., and Neuhaus, P. (2004) Brain death associated ischemia/reperfusion injury. Ann. Transplant. 9, 78-80
4. Gueler, F., Gwinner, W., Schwarz, A., and Haller, H. (2004) Long-term effects of acute ischemia and reperfusion injury. Kidney Int. 66, 523-527
5. Kosieradzki, M., and Rowinski, W. (2008) Ischemia/reperfusion injury in kidney transplantation: mechanisms and prevention. Transplant. Proc. 40, 3279-3288
6. Eltzschig, H. K., and Eckle, T. (2011) Ischemia and reperfusion: from mechanism to translation. Nat. Med. 17, 1391-1401
7. Perico, N., Cattaneo, D., Sayegh, M. H., and Remuzzi, G. (2004) Delayed graft function in kidney transplantation. Lancet 364, 1814-1827
8. Siedlecki, A., Irish, W., and Brennan, D. C. (2011) Delayed graft function in the kidney transplant. Am. J. Transplant. 11, 2279-2296
9. Herrero-Fresneda, I., Torras, J., Cruzado, J. M., Condom, E., Vidal, A., Riera, M., Lloberas, N., Alsina, J., and Grinyo, J. M. (2003) Do alloreactivity and prolonged cold ischemia cause different elementary lesions in chronic allograft nephropathy? Am. J. Pathol. 162, 127-137
10. Siriussawakul, A., Chen, L. I., and Lang, J. D. (2012) Medical gases: a novel strategy for attenuating ischemia-reperfusion injury in organ transplantation? J. Transplant. 2012, 819382
11. Nakao, A., Faleo, G., Shimizu, H., Nakahira, K., Kohmoto, J., Sugimoto, R., Choi, A. M., McCurry, K. R., Takahashi, T., and Murase, N. (2008) Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts. Kidney Int. 74, 1009-1016
12. Yoshida, J., Ozaki, K. S., Nalesnik, M. A., Ueki, S., Castillo-Rama, M., Faleo, G., Ezzelarab, M., Nakao, A., Ekser, B., Echeverri, G. J., Ross, M. A., Stolz, D. B., and Murase, N. (2010) Ex vivo application of carbon monoxide in UW solution prevents transplant-induced renal ischemia/reperfusion injury in pigs. Am. J. Transplant. 10, 763-772
13. Ma, D., Wilhelm, S., Maze, M., and Franks, N. P. (2002) Neuroprotective and neurotoxic properties of the 'inert' gas, xenon. Br. J. Anaesth. 89, 739-746
14. Weber, N. C., Toma, O., Wolter, J. I., Obal, D., Mullenheim, J., Preckel, B., and Schlack, W. (2005) The noble gas xenon induces pharmacological preconditioning in the rat heart in vivo via induction of PKC-epsilon and p38 MAPK. Br. J. Pharmacol. 144, 123-132
15. Weber, N. C., Frassdorf, J., Ratajczak, C., Grueber, Y., Schlack, W., Hollmann, M. W., and Preckel, B. (2008) Xenon induces late cardiac preconditioning in vivo: a role for cyclooxygenase 2? Anesth. Analg. 107, 1807-1813
16. Ma, D., Hossain, M., Pettet, G. K., Luo, Y., Lim, T., Akimov, S., Sanders, R. D., Franks, N. P., and Maze, M. (2006) Xenon preconditioning reduces brain damage from neonatal asphyxia in rats. J. Cereb. Blood Flow Metab. 26, 199-208
17. Ma, D., Hossain, M., Chow, A., Arshad, M., Battson, R. M., Sanders, R. D., Mehmet, H., Edwards, A. D., Franks, N. P., and Maze, M. (2005) Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia. Ann. Neurol. 58, 182-193
18. Schmidt, M., Marx, T., Gloggl, E., Reinelt, H., and Schirmer, U. (2005) Xenon attenuates cerebral damage after ischemia in pigs. Anesthesiology 102, 929-936
19. Limatola, V., Ward, P., Cattano, D., Gu, J., Giunta, F., Maze, M., and Ma, D. (2010) Xenon preconditioning confers neuroprotection regardless of gender in a mouse model of transient middle cerebral artery occlusion. Neuroscience 165, 874-881
20. Ma, D., Lim, T., Xu, J., Tang, H., Wan, Y., Zhao, H., Hossain, M., Maxwell, P. H., and Maze, M. (2009) Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J. Am. Soc. Nephrol. 20, 713-720
21. Zhao, H., Yoshida, A., Xiao, W., Ologunde, R., O'Dea, K. P., Takata, M., Tralau-Stewart, C., George, A. J., and Ma, D. (2013) Xenon treatment attenuates early renal allograft injury associated with prolonged hypothermic storage in rats. [E-pub ahead of print] FASEB J. doi:10.1096/fj.13-232173
22. Hamar, P., Song, E., Kokeny, G., Chen, A., Ouyang, N., and Lieberman, J. (2004) Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury. Proc. Natl. Acad. Sci. U. S. A. 101, 14883-14888
23. Brooks, C., Wei, Q., Cho, S. G., and Dong, Z. (2009) Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. J. Clin. Invest. 119, 1275-1285
24. Honda, H. M., Korge, P., and Weiss, J. N. (2005) Mitochondria and ischemia/reperfusion injury. Ann. N. Y. Acad. Sci. 1047, 248-258
25. Jassem, W., and Heaton, N. D. (2004) The role of mitochondria in ischemia/reperfusion injury in organ transplantation. Kidney Int. 66, 514-517
26. Jassem, W., Fuggle, S. V., Rela, M., Koo, D. D., and Heaton, N. D. (2002) The role of mitochondria in ischemia/reperfusion injury. Transplantation 73, 493-499
27. Gotoh, T., Terada, K., Oyadomari, S., and Mori, M. (2004) hsp70-DnaJ chaperone pair prevents nitric oxide-And CHOPinduced apoptosis by inhibiting translocation of Bax to mitochondria. Cell Death Differ. 11, 390-402
28. Kawai, A., Nishikawa, S., Hirata, A., and Endo, T. (2001) Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yeast cells. J. Cell Sci. 114, 3565-3574
29. Stankiewicz, A. R., Lachapelle, G., Foo, C. P., Radicioni, S. M., and Mosser, D. D. (2005) Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation. J. Biol. Chem. 280, 38729-38739
30. Wu, H., Ma, J., Wang, P., Corpuz, T. M., Panchapakesan, U., Wyburn, K. R., and Chadban, S. J. (2010) HMGB1 contributes to kidney ischemia reperfusion injury. J. Am. Soc. Nephrol. 21, 1878-1890
31. Lotze, M. T., and Tracey, K. J. (2005) High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5, 331-342
32. Benard, G., Bellance, N., James, D., Parrone, P., Fernandez, H., Letellier, T., and Rossignol, R. (2007) Mitochondrial bioenergetics and structural network organization. J. Cell Sci. 120, 838-848
33. Newmeyer, D. D., and Ferguson-Miller, S. (2003) Mitochondria: releasing power for life and unleashing the machineries of death. Cell 112, 481-490
34. Mapa, K., Sikor, M., Kudryavtsev, V., Waegemann, K., Kalinin, S., Seidel, C. A., Neupert, W., Lamb, D. C., and Mokranjac, D. (2010) The conformational dynamics of the mitochondrial Hsp70 chaperone. Mol. Cell 38, 89-100
35. Joza, N., Susin, S. A., Daugas, E., Stanford, W. L., Cho, S. K., Li, C. Y., Sasaki, T., Elia, A. J., Cheng, H. Y., Ravagnan, L., Ferri, K. F., Zamzami, N., Wakeham, A., Hakem, R., Yoshida, H., Kong, Y. Y., Mak, T. W., Zuniga-Pflucker, J. C., Kroemer, G., and Penninger, J. M. (2001) Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410, 549-554
36. Ow, Y. P., Green, D. R., Hao, Z., and Mak, T. W. (2008) Cytochrome c: functions beyond respiration. Nat. Rev. Mol. Cell Biol. 9, 532-542
37. Wu, H., Chen, G., Wyburn, K. R., Yin, J., Bertolino, P., Eris, J. M., Alexander, S. I., Sharland, A. F., and Chadban, S. J. (2007) TLR4 activation mediates kidney ischemia/reperfusion injury. J. Clin. Invest. 117, 2847-2859
38. Shah, N., and Langone, A. (2010) Renal donation after cardiac death. J. Am. Soc. Nephrol. 21, 888-890
39. Pratschke, J., Neuhaus, P., and Tullius, S. G. (2005) What can be learned from brain-death models? Transpl. Int. 18, 15-21
40. Manara, A. R., Murphy, P. G., and O'Callaghan, G. (2012) Donation after circulatory death. Br. J. Anaesth. 108(Suppl. 1), i108-i121
41. Lachmann, B., Armbruster, S., Schairer, W., Landstra, M., Trouwborst, A., Van Daal, G. J., Kusuma, A., and Erdmann, W. (1990) Safety and efficacy of xenon in routine use as an inhalational anaesthetic. Lancet 335, 1413-1415
42. Sanders, R. D., Ma, D., and Maze, M. (2004) Xenon: elemental anaesthesia in clinical practice. Br. Med. Bull. 71, 115-135
43. Rawat, S., and Dingley, J. (2010) Closed-circuit xenon delivery using a standard anesthesia workstation. Anesth. Analg. 110, 101-109