Lupus in Africa: Can we dispel the myths and face the challenges?

Lupus

Volumn 23, Issue 1, 2014, Pages 102-111

  Tiffin, N ^a   Hodkinson, B ^b   Okpechi, I ^b  

^a UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Africa; ALUGEN; lupus; lupus nephritis; SLE; Systemic lupus erythematosus

Indexed keywords

MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

AFRICA; ARTICLE; DRUG COST; HEALTH CARE ACCESS; HEALTH SURVEY; HUMAN; OUTCOME ASSESSMENT; PHYSICIAN; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

AFRICA; ALUGEN; LUPUS; LUPUS NEPHRITIS; SLE; SYSTEMIC LUPUS ERYTHEMATOSUS;

AFRICA; COMMUNITY NETWORKS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC;

EID: 84890456519     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203313509296     Document Type: Article

References (55)

1. Tiffin N, Adeyemo A, Okpechi I. A diverse array of genetic factors contribute to the pathogenesis of systemic lupus erythematosus. Orphanet J Rare Dis. 2013 ; 8: 2-2
2. Siegel M, Lee SL. The epidemiology of systemic lupus erythematosus. Semin Arthritis Rheum. 1973 ; 3: 1-54
3. Goldman MB, Hatch MC. Women and health. Academic Press (U.S.A.), 1999.
4. Danchenko N, Satia JA, Anthony MS. Epidemiology of systemic lupus erythematosus: A comparison of worldwide disease burden. Lupus. 2006 ; 15: 308-318
5. Kumar K, Chambers S, Gordon C. Challenges of ethnicity in SLE. Best Pract Res Clin Rheumatol. 2009 ; 23: 549-561
6. Greenwood BM. Autoimmune disease and parasitic infections in Nigerians. Lancet. 1968 ; 2: 380-382
7. Symmons DP. Frequency of lupus in people of African origin. Lupus. 1995 ; 4: 176-178
8. Butcher GA. Malaria and macrophage function in Africans: A possible link with autoimmune disease?. Med Hypotheses. 1996 ; 47: 97-100
9. Clark IA, al-Yaman FM, Cowden WB, Rockett KA. Does malarial tolerance, through nitric oxide, explain the low incidence of autoimmune disease in tropical Africa?. Lancet. 1996 ; 348: 1492-1494
10. Adebajo AO. Low frequency of autoimmune disease in tropical Africa. Lancet. 1997 ; 349: 361-362
11. Bae S-C, Fraser P, Liang MH. The epidemiology of systemic lupus erythematosus in populations of African ancestry: A critical review of the "prevalence gradient hypothesis". Arthritis Rheum. 1998 ; 41: 2091-2099
12. Tikly M, Burgin S, Mohanlal P, Bellingan A, George J. Autoantibodies in black South Africans with systemic lupus erythematosus: Spectrum and clinical associations. Clin Rheumatol. 1996 ; 15: 261-265
13. Molokhia M, McKeigue PM, Cuadrado M, Hughes G. Systemic lupus erythematosus in migrants from west Africa compared with Afro-Caribbean people in the UK. Lancet. 2001 ; 357: 1414-1415
14. Faller G, Thomson PD, Kala UK, Hahn D. Demographics and presenting clinical features of childhood systemic lupus erythematosus. S Afr Med J. 2005 ; 95: 424-427
15. Abdou N, Boucar D, El Hadj Fary KA, et al. Histopathological profiles of nephropathies in Senegal. Saudi J Kidney Dis Transplant. 2003 ; 14: 212-214
16. Adelowo OO, Oguntona SA. Pattern of systemic lupus erythematosus among Nigerians. Clin Rheumatol. 2009 ; 28: 699-703
17. Uribe AG, McGwin G Jr, Reveille JD, Alarcón GS. What have we learned from a 10-year experience with the LUMINA (Lupus in Minorities; Nature vs. nurture) cohort? Where are we heading?. Autoimmun Rev. 2004 ; 3: 321-329
18. Uribe AG, Vilá LM, McGwin G Jr, Sanchez ML, Reveille JD, Alarcón GS. The Systemic Lupus Activity Measure-revised, the Mexican Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and a modified SLEDAI-2K are adequate instruments to measure disease activity in systemic lupus erythematosus. J Rheumatol. 2004 ; 31: 1934-1940
19. Wadee S, Tikly M, Hopley M. Causes and predictors of death in South Africans with systemic lupus erythematosus. Rheumatol Oxf Engl. 2007 ; 46: 1487-1491
20. Ansell SM, Bedhesi S, Ruff B, et al. Study of critically ill patients with systemic lupus erythematosus. Crit Care Med. 1996 ; 24: 981-984
21. Hodkinson B, Musenge E, Tikly M. Osteoarticular tuberculosis in patients with systemic lupus erythematosus. QJM. 2009 ; 102: 321-328
22. Gould T, Tikly M. Systemic lupus erythematosus in a patient with human immunodeficiency virus infection - challenges in diagnosis and management. Clin Rheumatol. 2004 ; 23: 166-169
23. Barsoum RS, Francis MR. Spectrum of glomerulonephritis in Egypt. Saudi J Kidney Dis Transpl. 2000 ; 11: 421-429
24. Ibrahim S, Fayed A, Fadda S, Belal D. A five-year analysis of the incidence of glomerulonephritis at Cairo University Hospital-Egypt. Saudi J Kidney Dis Transplant. 2012 ; 23: 866-870
25. Van Rensburg BWJ, van Staden AM, Rossouw GJ, Joubert G. The profile of adult nephrology patients admitted to the Renal Unit of the Universitas Tertiary Hospital in Bloemfontein, South Africa from 1997 to 2006. Nephrol Dial Transplant. 2010 ; 25: 820-824
26. Okpechi I, Swanepoel C, Duffield M, et al. Patterns of renal disease in Cape Town South Africa: A 10-year review of a single-centre renal biopsy database. Nephrol Dial Transplant. 2011 ; 26: 1853-1861
27. Abdelraheem MB, Ali El-TM, Mohamed RM, et al. Pattern of glomerular diseases in Sudanese children: A clinico-pathological study. Saudi J Kidney Dis Transplant. 2010 ; 21: 778-783
28. Mesquita M, Fosso C, Bakoto Sol E, et al. Renal biopsy findings in Belgium: A retrospective single center analysis. Acta Clin Belg. 2011 ; 66: 104-109
29. Polito MG, de Moura LAR, Kirsztajn GM. An overview on frequency of renal biopsy diagnosis in Brazil: Clinical and pathological patterns based on 9,617 native kidney biopsies. Nephrol Dial Transplant. 2010 ; 25: 490-496
30. Li L-S, Liu Z-H. Epidemiologic data of renal diseases from a single unit in China: Analysis based on 13,519 renal biopsies. Kidney Int. 2004 ; 66: 920-923
31. Rychlík I, Jancová E, Tesar V, et al. The Czech registry of renal biopsies. Occurrence of renal diseases in the years 1994-2000. Nephrol Dial Transplant. 2004 ; 19: 3040-3049
32. Schena FP. Survey of the Italian Registry of Renal Biopsies. Frequency of the renal diseases for 7 consecutive years. The Italian Group of Renal Immunopathology. Nephrol Dial Transplant. 1997 ; 12: 418-426
33. Huraib S, Al Khader A, Shaheen FA, et al. The spectrum of glomerulonephritis in Saudi Arabia: The results of the Saudi registry. Saudi J Kidney Dis Transplant. 2000 ; 11: 434-441
34. Naumovic R, Pavlovic S, Stojkovic D, Basta-Jovanovic G, Nesic V. Renal biopsy registry from a single centre in Serbia: 20 years of experience. Nephrol Dial Transplant. 2009 ; 24: 877-885
35. Rivera F, López-Gómez JM, Pérez-García R.. Frequency of renal pathology in Spain 1994-1999. Nephrol Dial Transplant. 2002 ; 17: 1594-1602
36. Khalifa EH, Kaballo BG, Suleiman SM, Khalil EA, El-Hassan AM. Pattern of glomerulonephritis in Sudan: Histopathological and immunofluorescence study. Saudi J Kidney Dis Transplant. 2004 ; 15: 176-179
37. Elkhatib M, Elnahed MS, Fadda S, Eldeeb M, Saadi G. The change in the spectrum of glomerulonephritis in Egypt over the past decade. Saudi J Kidney Dis Transplant. 2012 ; 23: 1065-1067
38. Okpechi IG, Swanepoel CR, Tiffin N, Duffield M, Rayner BL. Clinicopathological insights into lupus nephritis in South Africans: A study of 251 patients. Lupus. 2012 ; 21: 1017-1024
39. Alarcón GS, McGwin G Jr, Bartolucci AA, et al. Systemic lupus erythematosus in three ethnic groups. IX. Differences in damage accrual. Arthritis Rheum. 2001 ; 44: 2797-2806
40. Krishnan E, Hubert HB. Ethnicity and mortality from systemic lupus erythematosus in the US. Ann Rheum Dis. 2006 ; 65: 1500-1505
41. Ayodele OE, Okpechi IG, Swanepoel CR. Long-term renal outcome and complications in South Africans with proliferative lupus nephritis. Int Urol Nephrol. Epub ahead of print 10 January 2013.
42. Sabry A, Abo-Zenah H, Medhat T, Sheashaa H, Mahmoud K, El-Huseini A. A comparative study of two intensified pulse cyclophosphamide remission-inducing regimens for diffuse proliferative lupus nephritis: An Egyptian experience. Int Urol Nephrol. 2009 ; 41: 153-161
43. Okpechi IG, Ayodele OE, Jones ESW, Duffield M, Swanepoel CR. Outcome of patients with membranous lupus nephritis in Cape Town South Africa. Nephrol Dial Transplant. 2012 ; 27: 3509-3515
44. Ayodele OE, Okpechi IG, Swanepoel CR. Predictors of poor renal outcome in patients with biopsy-proven lupus nephritis. Nephrol Carlton Vic. 2010 ; 15: 482-490
45. Kammoun K, Jarraya F, Bouhamed L, et al. Poor prognostic factors of lupus nephritis. Saudi J Kidney Dis Transplant. 2011 ; 22: 727-732
46. Benitha R, Tikly M. Functional disability and health-related quality of life in South Africans with rheumatoid arthritis and systemic lupus erythematosus. Clin Rheumatol. 2007 ; 26: 24-29
47. The World Health Organization. The World Health Report 2002: Reducing risks, promoting healthy life, http://www.who.int/whr/2002/en/whr02-en.pdf (2002, accessed 13 June 2013).
48. Ekwom PE. Systemic lupus erythematosus (SLE) at the Kenyatta National Hospital. Clin Rheumatol. 2013 ; 32: 1215-1217
49. Katz IJ, Gerntholtz T, Naicker S. Africa and nephrology: The forgotten continent. Nephron Clin Pract. 2011 ; 117: c320 - c327
50. Uribe AG, Ho KT, Agee B, McGwin G Jr, et al. Relationship between adherence to study and clinic visits in systemic lupus erythematosus patients: Data from the LUMINA cohort. Lupus. 2004 ; 13: 561-468
51. Health Metrics Network: What it is, what it will do and how countries can benefit. The World Health Organization/Health Metrics Network,www.who.int/ healthmetrics/about/concept-paper.doc (2005, accessed 6 July 2013).
52. Meyer PWA, Hodkinson B, Ally M, et al. HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients. Arthritis Res Ther. 2011 ; 13: R160 - R160
53. Dieye A, Diallo S, Diatta M, et al. Identification of HLA-DR alleles for susceptibility to rheumatoid polyarthritis in Senegal [in French]. Dakar Médical. 1997 ; 42: 111-113
54. Houman MH, Smiti-Khanfir M, Ben Ghorbell I, Miled M. Systemic lupus erythematosus in Tunisia: Demographic and clinical analysis of 100 patients. Lupus. 2004 ; 13: 204-211
55. Taylor HG, Stein CM. Systemic lupus erythematosus in Zimbabwe. Ann Rheum Dis. 1986 ; 45: 645-648