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Volumn 32, Issue 12, 2013, Pages 1697-1702

A meta-analysis of the role of p38 mitogen-activated protein kinase inhibitors in patients with active rheumatoid arthritis

Author keywords

Meta analysis; p38 Mitogen activated protein kinase inhibitors; Rheumatoid arthritis

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PAMAPIMOD; PLACEBO; TALMAPIMOD; VX 702;

EID: 84890441590     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-013-2340-1     Document Type: Review
Times cited : (5)

References (19)
  • 1
    • 84863861008 scopus 로고    scopus 로고
    • Understanding the dynamics: Pathways involved in the pathogenesis of rheumatoid arthritis
    • 10.1093/rheumatology/kes113 1:CAS:528:DC%2BC38XpsVahtbs%3D
    • Choy E (2012) Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford) 51(Suppl 5):v3-v11
    • (2012) Rheumatology (Oxford) , vol.51 , Issue.SUPPL. 5
    • Choy, E.1
  • 2
    • 84866614151 scopus 로고    scopus 로고
    • Progress toward personalized treatment of rheumatoid arthritis
    • 22910444 10.1038/clpt.2012.124 1:STN:280:DC%2BC38bgtFShuw%3D%3D
    • Keith MP, Edison JD, Gilliland WR (2012) Progress toward personalized treatment of rheumatoid arthritis. Clin Pharmacol Ther 92(4):440-442
    • (2012) Clin Pharmacol Ther , vol.92 , Issue.4 , pp. 440-442
    • Keith, M.P.1    Edison, J.D.2    Gilliland, W.R.3
  • 3
    • 39649098693 scopus 로고    scopus 로고
    • Pro-inflammatory cytokine-induced SAPK/MAPK and JAK/STAT in rheumatoid arthritis and the new anti-depression drugs
    • 18208366 10.1517/14728222.12.2.171 1:CAS:528:DC%2BD1cXovFCqtg%3D%3D
    • Malemud CJ, Miller AH (2008) Pro-inflammatory cytokine-induced SAPK/MAPK and JAK/STAT in rheumatoid arthritis and the new anti-depression drugs. Expert Opin Ther Targets 12(2):171-183
    • (2008) Expert Opin Ther Targets , vol.12 , Issue.2 , pp. 171-183
    • Malemud, C.J.1    Miller, A.H.2
  • 4
    • 43049158204 scopus 로고    scopus 로고
    • MAPKs and their relevance to arthritis and inflammation
    • 18187523 10.1093/rheumatology/kem297 1:CAS:528:DC%2BD1cXmslKhtrY%3D
    • Thalhamer T, McGrath MA, Harnett MM (2008) MAPKs and their relevance to arthritis and inflammation. Rheumatology 47(4):409-414
    • (2008) Rheumatology , vol.47 , Issue.4 , pp. 409-414
    • Thalhamer, T.1    McGrath, M.A.2    Harnett, M.M.3
  • 6
    • 0141788311 scopus 로고    scopus 로고
    • Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653
    • 13130488 10.1002/art.11227 1:CAS:528:DC%2BD3sXot1WjtL4%3D
    • Nishikawa M, Myoui A, Tomita T, Takahi K, Nampei A, Yoshikawa H (2003) Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653. Arthritis Rheum 48(9):2670-2681
    • (2003) Arthritis Rheum , vol.48 , Issue.9 , pp. 2670-2681
    • Nishikawa, M.1    Myoui, A.2    Tomita, T.3    Takahi, K.4    Nampei, A.5    Yoshikawa, H.6
  • 7
    • 20044394432 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) and pharmacodynamics (PD) of SCIO-469, a p38a MAP kinase inhibitor
    • 10.1016/j.clpt.2003.11.203
    • Amakye D, Tong S, Ward C, Beazley W (2004) Pharmacokinetics (PK) and pharmacodynamics (PD) of SCIO-469, a p38a MAP kinase inhibitor. Clin Pharmacol Ther 75:P54
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 54
    • Amakye, D.1    Tong, S.2    Ward, C.3    Beazley, W.4
  • 9
    • 59649114148 scopus 로고    scopus 로고
    • Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis
    • 19180516 10.1002/art.24266 1:CAS:528:DC%2BD1MXjt1CgtL4%3D
    • Cohen SB, Cheng TT, Chindalore V, Damjanov N, Burgos-Vargas R, Delora P, Zimany K, Travers H, Caulfield JP (2009) Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis. Arthritis Rheum 60(2):335-344
    • (2009) Arthritis Rheum , vol.60 , Issue.2 , pp. 335-344
    • Cohen, S.B.1    Cheng, T.T.2    Chindalore, V.3    Damjanov, N.4    Burgos-Vargas, R.5    Delora, P.6    Zimany, K.7    Travers, H.8    Caulfield, J.P.9
  • 10
    • 0035808035 scopus 로고    scopus 로고
    • Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses
    • 11730399 10.7326/0003-4819-135-11-200112040-00010 1:STN:280: DC%2BD3MnovVygsg%3D%3D
    • Kjaergard LL, Villumsen J, Gluud C (2001) Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses. Ann Intern Med 135(11):982-989
    • (2001) Ann Intern Med , vol.135 , Issue.11 , pp. 982-989
    • Kjaergard, L.L.1    Villumsen, J.2    Gluud, C.3
  • 11
    • 75749115980 scopus 로고    scopus 로고
    • Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy
    • 19357113 10.1136/ard.2008.104802 1:STN:280:DC%2BC3c%2Fls1WmtA%3D%3D
    • Alten RE, Zerbini C, Jeka S, Irazoque F, Khatib F, Emery P, Bertasso A, Rabbia M, Caulfield JP (2010) Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy. Ann Rheum Dis 69(2):364-367
    • (2010) Ann Rheum Dis , vol.69 , Issue.2 , pp. 364-367
    • Alten, R.E.1    Zerbini, C.2    Jeka, S.3    Irazoque, F.4    Khatib, F.5    Emery, P.6    Bertasso, A.7    Rabbia, M.8    Caulfield, J.P.9
  • 12
    • 66049086274 scopus 로고    scopus 로고
    • Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies
    • 19404957 10.1002/art.24485
    • Damjanov N, Kauffman RS, Spencer-Green GT (2009) Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies. Arthritis Rheum 60(5):1232-1241
    • (2009) Arthritis Rheum , vol.60 , Issue.5 , pp. 1232-1241
    • Damjanov, N.1    Kauffman, R.S.2    Spencer-Green, G.T.3
  • 13
    • 79955563297 scopus 로고    scopus 로고
    • A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis
    • 21285160 10.3899/jrheum.100602 1:CAS:528:DC%2BC3MXnvVeitrw%3D
    • Genovese MC, Cohen SB, Wofsy D, Weinblatt ME, Firestein GS, Brahn E, Strand V, Baker DG, Tong SE (2011) A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis. J Rheumatol 38(5):846-854
    • (2011) J Rheumatol , vol.38 , Issue.5 , pp. 846-854
    • Genovese, M.C.1    Cohen, S.B.2    Wofsy, D.3    Weinblatt, M.E.4    Firestein, G.S.5    Brahn, E.6    Strand, V.7    Baker, D.G.8    Tong, S.E.9
  • 14
    • 77956566269 scopus 로고    scopus 로고
    • A proof-of-concept and drug-drug interaction study of pamapimod, a novel p38 MAP kinase inhibitor, with methotrexate in patients with rheumatoid arthritis
    • 20100913 10.1177/0091270009357433 1:CAS:528:DC%2BC3cXhtFKku7rJ
    • Zhang X, Huang Y, Navarro MT, Hisoire G, Caulfield JP (2010) A proof-of-concept and drug-drug interaction study of pamapimod, a novel p38 MAP kinase inhibitor, with methotrexate in patients with rheumatoid arthritis. J Clin Pharmacol 50(9):1031-1038
    • (2010) J Clin Pharmacol , vol.50 , Issue.9 , pp. 1031-1038
    • Zhang, X.1    Huang, Y.2    Navarro, M.T.3    Hisoire, G.4    Caulfield, J.P.5
  • 17
    • 84926361529 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of VX-745, an oral p38 mitogen activated protein kinase (MAPK) inhibitor, in patients with rheumatoid arthritis (RA) [abstract]
    • Abstract FRI0018. Accessed 12 June 2002
    • Weisman M, Furst D, Schiff M, Kauffman R, Merica E, Martin-Munley S, et al. (2002) A double-blind, placebo-controlled trial of VX-745, an oral p38 mitogen activated protein kinase (MAPK) inhibitor, in patients with rheumatoid arthritis (RA) [abstract]. Presented at the 2002 annual European Congress of Rheumatology; Stockholm, Sweden. Abstract FRI0018. URL: http://www.eular.org. Accessed 12 June 2002
    • (2002) 2002 Annual European Congress of Rheumatology; Stockholm, Sweden
    • Weisman, M.1    Furst, D.2    Schiff, M.3    Kauffman, R.4    Merica, E.5    Martin-Munley, S.6
  • 18
    • 33644756429 scopus 로고    scopus 로고
    • Oral p38 mitogenactivated protein kinase inhibition with BIRB 796 for active Crohn's disease: A randomized, double-blind, placebo-controlled trial
    • Schreiber S, Feagan B, D'Haens G, Colombel JF, Geboes K, Yurcov M, Isakov V, Golovenko O, Bernstein CN, Ludwig D, Winter T, Meier U, Yong C, Steffgen J, BIRB 796 Study Group 10.1016/j.cgh.2005.11.013
    • Schreiber S, Feagan B, D'Haens G, Colombel JF, Geboes K, Yurcov M, Isakov V, Golovenko O, Bernstein CN, Ludwig D, Winter T, Meier U, Yong C, Steffgen J, BIRB 796 Study Group (2006) Oral p38 mitogenactivated protein kinase inhibition with BIRB 796 for active Crohn's disease: a randomized, double-blind, placebo-controlled trial. Clin Gastroenterol Hepatol 4(3):325-334
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.3 , pp. 325-334
  • 19
    • 21544433855 scopus 로고    scopus 로고
    • Scio-469, a novel p38α MAPK inhibitor, provides efficacy in acute post-surgical dental pain
    • 10.1016/j.clpt.2003.11.011
    • Tong SE, Daniels SE, Nontano T, Chang S, Desjardins P (2004) Scio-469, a novel p38α MAPK inhibitor, provides efficacy in acute post-surgical dental pain. Clin Pharmacol Ther 75(2):P3-P3
    • (2004) Clin Pharmacol Ther , vol.75 , Issue.2
    • Tong, S.E.1    Daniels, S.E.2    Nontano, T.3    Chang, S.4    Desjardins, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.