Randomized controlled trial of alfacalcidol supplementation for the reduction of hypocalcemia after total thyroidectomy

American Journal of Surgery

Volumn 207, Issue 1, 2014, Pages 39-45

  Genser, Laurent ^a   Trésallet, Christophe ^a   Godiris Petit, Gaëlle ^a   Li Sun Fui, Stéphanie ^a   Salepcioglu, Harika ^a   Royer, Catherine ^a   Menegaux, Fabrice ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Active vitamin D; Alfacalcidol; Hypocalcemia; Total thyroidectomy; Vitamin D

Indexed keywords

ALFACALCIDOL; CALCIUM; CALCIUM CARBONATE; COLECALCIFEROL;

ADULT; AGED; ARTICLE; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; CONVALESCENCE; FEMALE; FOLLOW UP; HUMAN; HYPOCALCEMIA; HYPOPARATHYROIDISM; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PERIOPERATIVE PERIOD; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURGICAL PATIENT; THYROID CARCINOMA; THYROIDECTOMY; TOXIC GOITER; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

ACTIVE VITAMIN D; ALFACALCIDOL; HYPOCALCEMIA; TOTAL THYROIDECTOMY; VITAMIN D;

ADULT; AGED; BONE DENSITY CONSERVATION AGENTS; CALCIUM; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYDROXYCHOLECALCIFEROLS; HYPOCALCEMIA; HYPOPARATHYROIDISM; MALE; MIDDLE AGED; THYROIDECTOMY; TIME FACTORS; TREATMENT OUTCOME; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84890430679     PISSN: 00029610     EISSN: 18791883     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2013.05.007     Document Type: Article

References (30)

1. D.B. De Roy van Zuidewijn, I. Songun, and J. Kievit Complications of thyroid surgery Ann Surg Oncol 2 1995 56 60
2. B. Abboud, Z. Sargi, and M. Akkam Risk factors for postthyroidectomy hypocalcemia J Am Coll Surg 195 2002 456 461
3. S.H. Chia, R.A. Weisman, and D. Tieu Prospective study of perioperative factors predicting hypocalcemia after thyroid and parathyroid surgery Arch Otolaryngol Head Neck Surg 132 2006 41 45
4. A. Duclos, J.-L. Peix, and C. Colin Influence of experience on performance of individual surgeons in thyroid surgery: prospective cross sectional multicentre study BMJ 344 2012 d8041
5. F. Pattou, F. Combemale, and S. Fabre Hypocalcemia following thyroid surgery: incidence and prediction of outcome World J Surg 22 1998 718 724
6. H. Yamashita, T. Murakami, and S. Noguchi Postoperative tetany in Graves disease: important role of vitamin D metabolites Ann Surg 229 1999 237 245
7. O. Thomusch, A. Machens, and C. Sekulla Multivariate analysis of risk factors for postoperative complications in benign goiter surgery: prospective multicenter study in Germany World J Surg 24 2000 1335 1341
8. O. Thomusch, A. Machens, and C. Sekulla The impact of surgical technique on postoperative hypoparathyroidism in bilateral thyroid surgery: a multivariate analysis of 5846 consecutive patients Surgery 133 2003 180 185
9. Y. Erbil, U. Barbaros, and B. Temel The impact of age, vitamin D(3) level, and incidental parathyroidectomy on postoperative hypocalcemia after total or near total thyroidectomy Am J Surg 197 2009 439 446
10. J. Kirkby-Bott, Z. El-Khatib, and B. Soudan 25-hydroxy vitamin D deficiency causes parathyroid incidentalomas Langenbecks Arch Surg 395 2010 919 924
11. J. Kirkby-Bott, H. Markogiannakis, and A. Skandarajah Preoperative vitamin D deficiency predicts postoperative hypocalcemia after total thyroidectomy World J Surg 35 2011 324 330
12. F.D. Moore Jr. Oral calcium supplements to enhance early hospital discharge after bilateral surgical treatment of the thyroid gland or exploration of the parathyroid glands J Am Coll Surg 178 1994 11 16
13. B. Abboud, G. Sleilaty, and S. Zeineddine Is therapy with calcium and vitamin D and parathyroid autotransplantation useful in total thyroidectomy for preventing hypocalcemia? Head Neck 30 2008 1148 1154
14. S. Moe, L.D. Wazny, and J.E. Martin Oral calcitriol versus oral alfacalcidol for the treatment of secondary hyperparathyroidism in patients receiving hemodialysis: a randomized, crossover trial Can J Clin Pharmacol 15 2008 e36 e43
15. J.-L. Roh, J.-Y. Park, and C.I. Park Prevention of postoperative hypocalcemia with routine oral calcium and vitamin D supplements in patients with differentiated papillary thyroid carcinoma undergoing total thyroidectomy plus central neck dissection Cancer 115 2009 251 258
16. J.-L. Roh, and C.I. Park Routine oral calcium and vitamin D supplements for prevention of hypocalcemia after total thyroidectomy Am J Surg 192 2006 675 678
17. F. Tartaglia, A. Giuliani, and M. Sgueglia Randomized study on oral administration of calcitriol to prevent symptomatic hypocalcemia after total thyroidectomy Am J Surg 190 2005 424 429
18. T. Uruno, A. Miyauchi, and K. Shimizu A prophylactic infusion of calcium solution reduces the risk of symptomatic hypocalcemia in patients after total thyroidectomy World J Surg 30 2006 304 308
19. A. Testa, V. Fant, and A. De Rosa Calcitriol plus hydrochlorothiazide prevents transient post-thyroidectomy hypocalcemia Horm Metab Res 38 2006 821 826
20. E.M. Brown Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers Physiol Rev 71 1991 371 411
21. M.I. Khan, S.G. Waguespack, and M.I. Hu Medical management of postsurgical hypoparathyroidism Endocr Pract 17 Suppl 1 2011 18 25
22. A. Sanabria, L.C. Dominguez, and V. Vega Routine postoperative administration of vitamin D and calcium after total thyroidectomy: a meta-analysis Int J Surg 9 2011 46 51
23. M. Raffaelli, C. De Crea, and C. Carrozza Combining early postoperative parathyroid hormone and serum calcium levels allows for an efficacious selective post-thyroidectomy supplementation treatment World J Surg 36 2012 1307 1313
24. R. Bellantone, C.P. Lombardi, and M. Raffaelli Is routine supplementation therapy (calcium and vitamin D) useful after total thyroidectomy? Surgery 132 2002 1109 1112
25. S. Grodski, and J. Serpell Evidence for the role of perioperative PTH measurement after total thyroidectomy as a predictor of hypocalcemia World J Surg 32 2008 1367 1373
26. P. Lecerf, D. Orry, and E. Perrodeau Parathyroid hormone decline 4 hours after total thyroidectomy accurately predicts hypocalcemia Surgery 152 2012 863 868
27. P. Nygren, R. Larsson, and H. Johansson 1,25(OH)2D3 inhibits hormone secretion and proliferation but not functional dedifferentiation of cultured bovine parathyroid cells Calcif Tissue Int 43 1988 213 218
28. D. Pisaniello, D. Parmeggiani, and A. Piatto Which therapy to prevent post-thyroidectomy hypocalcemia? G Chir 26 2005 357 361
29. L. Rosato, N. Avenia, and P. Bernante Complications of thyroid surgery: analysis of a multicentric study on 14,934 patients operated on in Italy over 5 years World J Surg 28 2004 271 276
30. J.A. Olson Jr., M.K. DeBenedetti, and D.S. Baumann Parathyroid autotransplantation during thyroidectomy. Results of long-term follow-up Ann Surg 223 1996 472 478