An evaluation of the morphologic features of low-grade mucinous neoplasms of the appendix metastatic in the ovary, and comparison with primary ovarian mucinous tumors

International Journal of Gynecological Pathology

Volumn 33, Issue 1, 2014, Pages 1-10

  Stewart, Colin J R ^a   Ardakani, Nima M ^a   Doherty, Dorota A ^a   Young, Robert H ^b  

^a KING EDWARD MEMORIAL HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Appendix; Borderline; LAMN; Mucinous tumor; Ovary; Teratoma

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CYTOKERATIN 20; CYTOKERATIN 7; MUCIN; VILLIN;

ADULT; AGED; APPENDIX TUMOR; ARTICLE; CANCER CELL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GRANULOMA; HISTIOCYTE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LOW GRADE APPENDICEAL MUCINOUS NEOPLASM; MICROSCOPY; MUCIN GRANULOMA; MUCINOUS CYSTIC NEOPLASM; OVARIAN MUCINOUS TUMOR; OVARY METASTASIS; OVARY TUMOR; PERITONEUM PSEUDOMYXOMA; PRIORITY JOURNAL; PSEUDOMYXOMA OVARII; PSEUDOTUMOR; STROMA; TERATOMA; TUMOR VOLUME;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; APPENDICEAL NEOPLASMS; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM GRADING; OVARIAN NEOPLASMS;

EID: 84890428974     PISSN: 02771691     EISSN: 15387151     Source Type: Journal    
DOI: 10.1097/PGP.0b013e318284e070     Document Type: Article

References (45)

1. Reichert RA, eds. Diagnostic Gynecologic and Obstetric Pathology. An Atlas and Text. Philadelphia: Lippincott Williams & Wilkins; 2012.
2. Stewart CJR, Brennan BA, Hammond IG, et al. Accuracy of frozen section in distinguishing primary ovarian neoplasia from tumors metastatic to the ovary. Int J Gynecol Pathol 2005;24:356-62.
3. RH Young. From krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part 1. Historical perspective, general principles, mucinous tumors including the krukenberg tumor. Adv Anat Pathol 2006;13:205-27.
4. McCluggageWG, Wilkinson N. Metastatic neoplasms involving the ovary: a review with an emphasis on morphological and immunohistochemical features. Histopathology 2005;47:231-47.
5. Baker P, Oliva E. A practical approach to intraoperative consultation in gynecological pathology. Int J Gynecol Pathol 2008;27:353-65.
6. Acs G. Intraoperative consultation in gynecologic pathology. Semin Diagn Pathol 2002;19:237-54.
7. Young RH. Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms. Semin Diagn Pathol 2004;21:134-50.
8. Pai RK, Longacre TA. Appendiceal mucinous tumors and pseudomyxoma peritoei. histologic features, diagnostic problems, and proposed classification. Adv Anat Pathol 2005;12: 291-311.
9. Misdraji J. Appendiceal mucinous neoplasms. Controversial issues. Arch Pathol Lab Med 2010;134:864-70.
10. Panarelli NC, Yantiss RK. Mucinous neoplasms of the appendix and peritoneum. Arch Pathol Lab Med 2011;135: 1261-8.
11. Ronnett BM, Seidman JD. Mucinous tumors arising in ovarian mature cystic teratomas. Relationship to the clinical syndrome of pseudomyxoma peritonei. Am J Surg Pathol 2003;27:650-7.
12. Stewart CJR, Tsukamoto T, Cooke B, et al. Ovarian mucinous tumour arising in mature cystic teratoma and associated with pseudomyxoma peritonei: report of two cases and comparison with ovarian involvement by low-grade appendiceal mucinous tumour. Pathology 2006;38:534-8.
13. Vang R, Gowan AM, Zhao C, et al. Ovarian mucinous tumors associated with mature cystic teratomas: morphologic and immunohistochemical analysis identifies a subset of potential teratomatous origin that shares features of lower gastrointestinal tract mucinous tumors more commonly encountered as secondary tumors in the ovary. Am J Surg Pathol 2007;31:854-69.
14. McKenney JK, Soslow RA, Longacre TA. Ovarian mature teratomas with mucinous epithelial neoplasms: morphologic heterogeneity and association with pseudomyxoma peritonei. Am J Surg Pathol 2008;32:645-55.
15. Bradley RF, Cortina G, Geisinger KR. Pseudomyxoma peritonei: review of the controversy. Curr Diagn Pathol 2007;13:410-6.
16. Edge SB, Byrd DR, Compton CC, et al, eds. AJCC Cancer Staging Manual. ; 7th ed New York: Springer; 2010.
17. Young RH, Gilks CB, Scully RE. Mucinous tumors of the appendix associated with mucinous tumors of the ovary and pseudomyxoma peritonei. A clinicopathological analysis of 22 cases supporting an origin in the appendix. Am J Surg Pathol 1991;15:415-29.
18. Misdraji J, Yantiss RK, Graeme-Cook FM, et al. Appendiceal mucinous neoplasms. A clinicopathologic analysis of 107 cases. Am J Surg Pathol 2003;27:1089-103.
19. Misdraji J, Young RH. Primary epithelial neoplasms and other epithelial lesions of the appendix (excluding carcinoid tumors). Semin Diagn Pathol 2004;21:120-33.
20. Ronnett BM, Kurman RJ, Zahn CM, et al. Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential. Hum Pathol 1995;26:509-24.
21. Stewart CJR, Junckerstorff R, Tsukamoto T. Ovarian mucinous tumor arising in mature cystic teratoma associated with pseudomyxoma peritonei: a case with possible respiratory differentiation. Int J Gynecol Pathol 2008;27:41-3.
22. Khunamornpong S, Russell P, Dalrymple JC. Proliferating (LMP) mucinous tumors of the ovaries with microinvasion: morphologic assessment of 13 cases. Int J Gynecol Pathol 1999;18:238-46.
23. Hart WR. Mucinous tumors of the ovary: a review. Int J Gynecol Pathol 2005;24:4-25.
24. Acs G. Serous and mucinous borderline (low malignant potential) tumors of the ovary. Am J Clin Pathol 2005;123: S13-57.
25. Lerwill MF, Young RH. Mucinous tumours of the ovary. Diagn Histopathol 2008;14:366-87.
26. Kim KR, Lee HI, Lee SK, et al. Is stromal microinvasion in primary mucinous ovarian tumors with ''mucin granuloma'' true invasion? Am J Surg Pathol 2007;31:546-54.
27. Stewart CJR, Brennan BA, Leung YC, et al. Intraoperative assessment of ovarian tumors: a 5-year review with assessment of discrepant diagnostic cases. Int J Gynecol Pathol 2006;25:216-22.
28. Stewart CJR, Brennan BA, Koay E, et al. Evaluation of cytology in the intra-operative assessment of ovarian tumors: a review of 402 cases and comparison with frozen section diagnosis. Cancer Cytopathol 2010;118:127-36.
29. Leen SL, Singh N. Pathology of primary and metastatic mucinous ovarian neoplasms. J Clin Pathol 2012;65:591-5.
30. Seidman JD, Kurman RJ, Ronnett BM. Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine practice with a new approach to improve intraoperative diagnosis. Am J Surg Pathol 2003;27:985-93.
31. Lee KR, Young RH. The distinction between primary and metastatic mucinous carcinomas of the ovary: gross and histologic findings in 50 cases. AmJ Surg Pathol 2003;27:281-92.
32. Vang R, Gown AM, Barry TS, et al. Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases. Am J Surg Pathol 2006;30:1130-9.
33. Vang R, Gown AM, Wu LS, et al. Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7. Mod Pathol 2006;19:1421-8.
34. McCluggage WG. Immunohistochemistry in the distinction between primary and metastatic ovarian mucinous neoplasms. J Clin Pathol 2012;65:596-600.
35. Pranesh N, Menasce LP, Wilson MS, et al. Pseudomyxoma peritonei: unusual origin from an ovarian mature cystic teratoma. J Clin Pathol 2005;58:1115-7.
36. Marquette S, Amant F, Vergote I, et al. Pseudomyxoma peritonei associated with a mucinous ovarian tumor arising from a mature cystic teratoma. A case report. Int J Gynecol Pathol 2006;25:340-3.
37. Hwang JH, So K-A, Modi G, et al. Borderline-like mucinous tumor arising in mature cystic teratoma of the ovary associated with pseudomyxoma peritonei. Int J Gynecol Pathol 2009;28:376-80.
38. Lerwill MF, Young RH. Metastatic tumors to the ovary. In: Kurman RJ, Ellenson LH, Ronnett BM, eds. Blaustein's Pathology of the Female Genital Tract. ; 6th ed New York: Springer; 2011:929-97.
39. Prayson RA, Hart WR, Petras RE. Psuedomyxoma peritonei. A clinicopathologic study of 19 cases with emphasis on site of origin and nature of associated ovarian tumors. Am J Surg Pathol 1994;18:591-603.
40. Nassar H. Carcinomas with micropapillary morphology: clinical significance and current concepts. Adv Anat Pathol 2004;11:297-303.
41. Nassar H, Pansare V, Zhang H, et al. Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoprotein. Mod Pathol 2004;17:1045-50.
42. Young RH, Srigley JR, Amin MB, et al. Tumors of the Prostate Gland, Seminal Vesicles, Male Urethra, and Penis. Atlas of Tumor Pathology, 3rd Series, Fascicle 28. Washington, DC: Armed Forces Institute of Pathology; 2000. Pages 111-216.
43. Ulrich M, Roewert-Huber J, Gonzalez S, et al. Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology. J Cutan Pathol 2011;38:190-5.
44. Abdullgaffar B. The prevalence and importance of clefts in cutaneous neoplasms. Pathology 2012;44:267-70.
45. Matias-Guiu X, Prat J. Ovarian tumors with functioning stroma. An immunohistochemical study of 100 cases with human chorionic gonadotrophin monoclonal and polyclonal antibodies. Cancer 1990;65:2001-5.