Albuminuria is associated with hip fracture risk in older adults: The cardiovascular health study

Osteoporosis International

Volumn 24, Issue 12, 2013, Pages 2993-3000

  Barzilay, J I ^a,b,i   Buzkova P ^c   Chen, Z ^d   De Boer, I H ^e   Carbone, L ^f   Rassouli, N N ^a,b   Fink, H A ^g   Robbins, J A ^h  

^a KAISER PERMANENTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ NONE   (United States)

Author keywords

Albuminuria; BMD; DEXA; Elderly; Hip fracture

Indexed keywords

ALBUMIN;

AGED; ALBUMINURIA; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; BONE DENSITY; CIRCULATION; DIABETES MELLITUS; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; ENERGY EXPENDITURE; FALLING; FEMALE; FOLLOW UP; FRAGILITY FRACTURE; GLOMERULUS FILTRATION RATE; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RACE; RISK FACTOR; SMOKING; URINE LEVEL;

AGED; AGED, 80 AND OVER; ALBUMINURIA; BONE DENSITY; FEMALE; FOLLOW-UP STUDIES; HIP FRACTURES; HIP JOINT; HUMANS; INCIDENCE; KAPLAN-MEIER ESTIMATE; MALE; OSTEOPOROTIC FRACTURES; RISK FACTORS; SEX FACTORS; UNITED STATES;

EID: 84890426471     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-013-2389-3     Document Type: Article

References (19)

1. Parfitt AM (2000) The mechanism of coupling: a role for the vasculature. Bone 26:319-23
2. Garg AX, Kiberd BA, Clark WF, Haynes RB, Clase CM (2002) Albuminuria and renal insufficiency prevalence guides population screening. Results from NHANES III. Kidney Int 61:2165-2175
3. Barzilay JI, Peterson D, Cushman M, Heckbert SR, Cao JJ, Blaum C, Tracy RP, Klein R, Herrington DM (2004) The relationship of cardiovascular risk factors to microalbuminuria in older adults with or without diabetes mellitus or hypertension; the Cardiovascular Health Study. Am J Kidney Dis 44:25-34
4. Redlich K, Smolen JS (2012) Inflammatory bone loss: pathogenesis and therapeutic intervention. Nat Rev Drug Discov 11:234-250
5. Burkhardt R, Kettner G, Böhm W, Schmidmeier M, Schlag R, Frisch B, Mallmann B, Eisenmenger W, Gilg T (1987) Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study. Bone 8:157-164
6. Griffith JF, Yeung DK, Tsang PH, Choi KC, Kwok TC, Ahuja AT, Leung KS, Leung PC (2008) Compromised bone marrow perfusion in osteoporosis. J Bone Miner Res 23:1068-1075
7. Laroche M, Ludot I, Thiechart M, Arlet J, Pieraggi M, Chiron P, Moulinier L, Cantagrel A, Puget J, Utheza G, Mazieres B (1995) Study of the intraosseous vessels of the femoral head in patients with fractures of the femoral neck or osteoarthritis of the hip. Osteoporos Int 5:213-217
8. Moseley KF (2012) Type 2 diabetes and bone fractures. Curr Opin Endocrinol Diabetes Obes 19:128-135
9. Vestergaard P, Rejnmark L, Mosekilde L (2009) Hypertension is a risk factor for fractures. Calcif Tissue Int 84:103-111
10. Jørgensen L, Jenssen T, Ahmed L, Bjornerem A, Joakimsen R, Jacobsen BK (2007) Albuminuria and risk of nonvertebral fractures. Arch Intern Med 167:1379-1385
11. Barzilay JI, Gao P, Clase K, Mente A, Mann JFE, Sleight P, Yusuf S, Teo KK, on behalf of the ONTARGET/TRANSCEND Investigators (2013) Albuminuria and rapid loss of glomerular filtration rate predict new hip and pelvic fractures: the ONTARGET/TRANSCEND studies. Clin J Am Soc Nephrol 8:233-240
12. Robbins JA, Biggs ML, Cauley J (2006) Adjusted mortality after hip fracture: from the Cardiovascular Health Study. J Am Geriatr Soc 54:1885-1891
13. Fried LP, Borhani NO, Enright P, Furberg CD, Gardin JM, Kronmal RA, Kuller LH, Manolio TA, Mittelmark MB, Newman A, O'Leary DH, Psaty B, Rautaharju P, Tracy RP, Weiler PG (1991) Cardiovascular Health Study: design and rationale. Ann Epidemiol 1:263-276
14. Barzilay JI, Blaum C, Moore T, Xue QL, Hirsch CH, Walston JD, Fried LP (2007) Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study. Arch Intern Med 167:635-641
15. Cushman M, Cornell ES, Howard PR, Bovill EG, Tracy RP (1995) Laboratory methods and quality assurance in the Cardiovascular Health Study. Clin Chem 41:264-270
16. R Development Core Team (2009) R: a language and environment for statistical computing. R Foundation for Statistical Computing: Vienna. ISBN 3-900051-07-0. http://www.R-project.org
17. Xue QL, Beamer BA, Chaves PH, Guralnik JM, Fried LP (2010) Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: the Women's Health and Aging Study II. J Am Geriatr Soc 58:2076-2084
18. Chen PJ, Lin MH, Peng LN, Liu CL, Chang CW, Lin YT, Chen LK (2012) Predicting cause-specific mortality of older men living in the Veterans home by handgrip strength and walking speed: a 3-year, prospective cohort study in Taiwan. J Am Med Dir Assoc 13:517-521
19. Brown M (2008) Skeletal muscle and bone: effect of sex steroids and aging. Adv Physiol Educ 32:120-126