Vascular endothelial growth factor levels in Dobrava/Belgrade virus infections

Viruses

Volumn 5, Issue 12, 2013, Pages 3109-3118

  Tsergouli, Katerina ^a   Papa, Anna ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Dobrava Belgrade virus; Greece; Hantavirus; Hemorrhagic fever with renal syndrome; Vascular endothelial growth factor

Indexed keywords

VASCULOTROPIN A;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD VESSEL INJURY; CHILD; CONTROLLED STUDY; CONVALESCENCE; DISEASE ASSOCIATION; DISEASE SEVERITY; DOBRAVA BELGRADE VIRUS; DOBRAVA BELGRADE VIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMAN; MAJOR CLINICAL STUDY; MALE; PERMEABILITY; RENAL REPLACEMENT THERAPY; VIRUS; VIRUS INFECTION;

ADOLESCENT; ADULT; AGED; CHILD; FEMALE; GREECE; HANTAVIRUS; HANTAVIRUS INFECTIONS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; MALE; MIDDLE AGED; SERUM; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 84890402107     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v5123109     Document Type: Article

References (26)

1. Papa, A. Crimean-Congo Hemorrhagic Fever and Hantavirus Infections. In Tropical and Emerging Infectious Diseases; Maltezou, H., Gikas, A., Eds.; Research Signpost: Kerala, India, 2010; pp. 49-73.
2. Avsic-Zupanc, T.; Petrovec, M.; Furlan, P.; Kaps, R.; Elgh, F.; Lundkvist, A. Hemorrhagic fever with renal syndrome in the Dolenjska region of Slovenia-a 10-year survey. Clin. Infect. Dis. 1999, 28, 860-865.
3. Papa, A.; Antoniadis, A. Hantavirus infections in Greece--an update. Eur. J. Epidemiol. 2001, 17, 189-194.
4. Antoniadis, A.; Stylianakis, A.; Papa, A.; Alexiou-Daniel, S.; Lampropoulos, A.; Nichol, S.T.; Peters, C.J.; Spiropoulou, C.F. Direct genetic detection of Dobrava virus in Greek and Albanian patients with hemorrhagic fever with renal syndrome. J. Infect. Dis. 1996, 174, 407-410.
5. Papa, A.; Johnson, A.M.; Stockton, P.C.; Bowen, M.D.; Spiropoulou, C.F.; Alexiou-Daniel, S.; Ksiazek, T.G.; Nichol, S.T.; Antoniadis, A. Retrospective serological and genetic study of the distribution of hantaviruses in Greece. J. Med. Virol. 1998, 55, 321-327.
6. Krautkramer, E.; Zeier, M.; Plyusnin, A. Hantavirus infection: An emerging infectious disease causing acute renal failure. Kidney Int. 2013, 83, 23-27.
7. Papa, A. Dobrava-Belgrade virus: Phylogeny, epidemiology, disease. Antivir. Res. 2012, 95, 104-117.
8. Klempa, B.; Avsic-Zupanc, T.; Clement, J.; Dzagurova, T.K.; Henttonen, H.; Heyman, P.; Jakab, F.; Kruger, D.H.; Maes, P.; Papa, A.; et al. Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: Definition of genotypes and their characteristics. Arch. Virol. 2012, 158, 521-529.
9. Fukasawa, H.; Bornheimer, S.; Kudlicka, K.; Farquhar, M.G. Slit diaphragms contain tight junction proteins. J. Am. Soc. Nephrol. 2009, 20, 1491-1503.
10. Reiser, J.; Kriz, W.; Kretzler, M.; Mundel, P. The glomerular slit diaphragm is a modified adherens junction. J. Am. Soc. Nephrol. 2000, 11, 1-8.
11. Schonrich, G.; Rang, A.; Lutteke, N.; Raftery, M.J.; Charbonnel, N.; Ulrich, R.G. Hantavirus-induced immunity in rodent reservoirs and humans. Immunol. Rev. 2008, 225, 163-189.
12. Bates, D.O. Vascular endothelial growth factors and vascular permeability. Cardiovasc. Res. 2010, 87, 262-271.
13. Gavrilovskaya, I.N.; Brown, E.J.; Ginsberg, M.H.; Mackow, E.R. Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins. J. Virol. 1999, 73, 3951-3959.
14. Raymond, T.; Gorbunova, E.; Gavrilovskaya, I.N.; Mackow, E.R. Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformers. Proc. Natl. Acad. Sci. USA 2005, 102, 1163-1168.
15. Krautkramer, E.; Grouls, S.; Stein, N.; Reiser, J.; Zeier, M. Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts. J. Virol. 2011, 85, 9811-9823.
16. Gavrilovskaya, I.N.; Gorbunova, E.E.; Mackow, N.A.; Mackow, E.R. Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability. J. Virol. 2008, 82, 5797-5806.
17. Gorbunova, E.E.; Gavrilovskaya, I.N.; Pepini, T.; Mackow, E.R. VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability. J. Virol. 2011, 85, 2296-2303.
18. Tseng, C.S.; Lo, H.W.; Teng, H.C.; Lo, W.C.; Ker, C.G. Elevated levels of plasma VEGF in patients with dengue hemorrhagic fever. FEMS Immunol. Med. Microbiol. 2005, 43, 99-102.
19. Taylor, S.L.; Wahl-Jensen, V.; Copeland, A.M.; Jahrling, P.B.; Schmaljohn, C.S. Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system. PLoS Pathog. 2013, 9, e1003470.
20. Ma, Y.; Liu, B.; Yuan, B.; Wang, J.; Yu, H.; Zhang, Y.; Xu, Z.; Yi, J.; Zhang, C.; Zhou, X.; et al. Sustained high level of serum VEGF at convalescent stage contributes to the renal recovery after HTNV Infection in patients with hemorrhagic fever with renal syndrome. Clin. Dev. Immunol. 2012, 2012, 812386.
21. Li, Y.; Wang, W.; Wang, J.P.; Pan, L.; Zhang, Y.; Yu, H.T.; Jiang, W.; Wang, P.Z.; Bai, X.F. Elevated vascular endothelial growth factor levels induce hyperpermeability of endothelial cells in hantavirus infection. J. Int. Med. Res. 2012, 40, 1812-1821.
22. Gavrilovskaya, I.; Gorbunova, E.; Koster, F.; Mackow, E. Elevated VEGF levels in pulmonary edema fluid and PBMCs from patients with acute hantavirus pulmonary syndrome. Adv. Virol. 2012, 2012, 674360.
23. Gorbunova, E.; Gavrilovskaya, I.N.; Mackow, E.R. Pathogenic hantaviruses Andes virus and Hantaan virus induce adherens junction disassembly by directing vascular endothelial cadherin internalization in human endothelial cells. J. Virol. 2010, 84, 7405-7411.
24. Shrivastava-Ranjan, P.; Rollin, P.E.; Spiropoulou, C.F. Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin. J. Virol. 2010, 84, 11227-11234.
25. Safronetz, D.; Zivcec, M.; Lacasse, R.; Feldmann, F.; Rosenke, R.; Long, D.; Haddock, E.; Brining, D.; Gardner, D.; Feldmann, H.; et al. Pathogenesis and host response in Syrian hamsters following intranasal infection with Andes virus. PLoS Pathog. 2011, 7, e1002426.
26. Spengler, J.R.; Haddock, E.; Gardner, D.; Hjelle, B.; Feldmann, H.; Prescott, J. Experimental Andes virus infection in deer mice: Characteristics of infection and clearance in a heterologous rodent host. PLoS One 2013, 8, e55310.