Left ventricular ejection time, not heart rate, is an independent correlate of aortic pulse wave velocity

Journal of Applied Physiology

Volumn 115, Issue 11, 2013, Pages 1610-1617

  Salvi, Paolo ^a   Palombo, Carlo ^b   Salvi, Giovanni Matteo ^a   Labat, Carlos ^c,d   Parati, Gianfranco ^a,e   Benetos, Athanase ^c,d  

^a ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c UNIVERSITÉ DE LORRAINE   (France)

^d UNIVERSITY HOSPITAL OF NANCY   (France)

^e UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Arterial stiffness; Heart rate; Left ventricular ejection time; Left ventricular function; Pulse wave velocity

Indexed keywords

ADOLESCENT; ADULT; AGED; AORTA; ARTERIAL STIFFNESS; ARTICLE; DIASTOLE; FEMALE; HEART; HEART LEFT VENTRICLE EJECTION TIME; HEART LEFT VENTRICLE FUNCTION; HEART RATE; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; PHYSIOLOGY; PULSE RATE; PULSE WAVE; VERY ELDERLY;

ARTERIAL STIFFNESS; HEART RATE; LEFT VENTRICULAR EJECTION TIME; LEFT VENTRICULAR FUNCTION; PULSE WAVE VELOCITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AORTA; DIASTOLE; FEMALE; HEART; HEART RATE; HUMANS; MALE; MIDDLE AGED; PULSE; PULSE WAVE ANALYSIS; VENTRICULAR FUNCTION, LEFT;

EID: 84890384771     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00475.2013     Document Type: Article

References (47)

1. Albaladejo P, Copie X, Boutouyrie P, Laloux B, Declere AD, Smulyan H, Benetos A. Heart rate, arterial stiffness, and wave reflections in paced patients. Hypertension 38: 949-952, 2001.
2. Alecu C, Gueguen R, Aubry C, Salvi P, Perret-Guillaume C, Ducrocq X, Vespignani H, Benetos A. Determinants of arterial stiffness in an apparently healthy population over 60 years. J Hum Hypertens 20: 749-756, 2006.
3. Alecu C, Labat C, Kearney-Schwartz A, Fay R, Salvi P, Joly L, Lacolley P, Vespignani H, Benetos A. Reference values of aortic pulse wave velocity in the elderly. J Hypertens 26: 2207-2212, 2008.
4. Armentano RL, Barra JG, Levenson J, Simon A, Pichel RH. Arterial wall mechanics in conscious dogs. Assessment of viscous, inertial, and elastic moduli to characterize aortic wall behavior. Circ Res 76: 468-478, 1995.
5. Benetos A, Adamopoulos C, Bureau JM, Temmar M, Labat C, Bean K, Thomas F, Pannier B, Asmar R, Zureik M, Safar M, Guize L. Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period. Circulation 105: 1202-1207, 2002.
6. Benetos A, Buatois S, Salvi P, Marino F, Toulza O, Dubail D, Manckoundia P, Valbusa F, Rolland Y, Hanon O, Gautier S, Miljkovic D, Guillemin F, Zamboni M, Labat C, Perret-Guillaume C. Blood pressure and pulse wave velocity values in the institutionalized elderly aged 80 and over: baseline of the PARTAGE study. J Hypertens 28: 41-50, 2010.
7. Benetos A, Gautier S, Labat C, Salvi P, Valbusa F, Marino F, Toulza O, Agnoletti D, Zamboni M, Dubail D, Manckoundia P, Rolland Y, Hanon O, Perret-Guillaume C, Lacolley P, Safar ME, Guillemin F. Mortality and cardiovascular events are best predicted by low central/ peripheral pulse pressure amplification but not by high blood pressure levels in elderly nursing home subjects: the PARTAGE (Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population) study. J Am Coll Cardiol 60: 1503-1511, 2012.
8. Benetos A, Watfa G, Hanon O, Salvi P, Fantin F, Toulza O, Manckoundia P, Agnoletti D, Labat C, Gautier S. Pulse wave velocity is associated with 1-year cognitive decline in the elderly older than 80 years: the PARTAGE study. J Am Med Dir Assoc 13: 239-243, 2012.
9. Boudoulas H. Systolic time intervals. Eur Heart J 11, Suppl I: 93-104, 1990.
10. Boudoulas H, Karayannacos PE, Lewis RP, Leier CV, Vasko JS. Effect of afterload on left ventricular performance in experimental animals. Comparison of the pre-ejection period and other indices of left ventricular contractility. J Med 13: 373-385, 1982.
11. Campese VM, Shaohua Y, Huiquin Z. Oxidative stress mediates angiotensin II-dependent stimulation of sympathetic nerve activity. Hypertension 46: 533-539, 2005.
12. Cheng K, Cameron JD, Tung M, Mottram PM, Meredith IT, Hope SA. Association of left ventricular motion and central augmentation index in healthy young men. J Hypertens 30: 2395-2402, 2012.
13. Cruickshank K, Riste L, Anderson SG, Wright JS, Dunn G, Gosling RG. Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 106: 2085-2090, 2002.
14. Giannattasio C, Salvi P, Valbusa F, Kearney-Schwartz A, Capra A, Amigoni M, Failla M, Boffi L, Madotto F, Benetos A, Mancia G. Simultaneous measurement of beat-to-beat carotid diameter and pressure changes to assess arterial mechanical properties. Hypertension 52: 896-902, 2008.
15. Haesler E, Lyon X, Pruvot E, Kappenberger L, Hayoz D. Confounding effects of heart rate on pulse wave velocity in paced patients with a low degree of atherosclerosis. J Hypertens 22: 1317-1322, 2004.
16. Joly L, Perret-Guillaume C, Kearney-Schwartz A, Salvi P, Mandry D, Marie PY, Karcher G, Rossignol P, Zannad F, Benetos A. Pulse wave velocity assessment by external noninvasive devices and phase-contrast magnetic resonance imaging in the obese. Hypertension 54: 421-426, 2009.
17. Kis E, Cseprekal O, Kerti A, Salvi P, Benetos A, Tisler A, Szabo A, Tulassay T, Reusz GS. Measurement of pulse wave velocity in children and young adults: a comparative study using three different devices. Hypertens Res 34: 1197-1202, 2011.
18. Lantelme P, Khettab F, Custaud MA, Rial MO, Joanny C, Gharib C, Milon H. Spontaneous baroreflex sensitivity: toward an ideal index of cardiovascular risk in hypertension? J Hypertens 20: 935-944, 2002.
19. Lantelme P, Mestre C, Lievre M, Gressard A, Milon H. Heart rate: an important confounder of pulse wave velocity assessment. Hypertension 39: 1083-1087, 2002.
20. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 37: 1236-1241, 2001.
21. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Struijker Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Dalby Kristensen S, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Erdine S, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Lindholm LH, Viigimaa M, Adamopoulos S, Agabiti-Rosei E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Lip G, Mallion JM, Manolis AJ, Nilsson PM, O'Brien E, Ponikowski P, Redon J, Ruschitzka F, Tamargo J, van Zwieten P, Waeber B, Williams B. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 25: 1105-1187, 2007.
22. Mangoni AA, Mircoli L, Giannattasio C, Ferrari AU, Mancia G. Heart rate-dependence of arterial distensibility in vivo. J Hypertens 14: 897-901, 1996.
23. Mangoni AA, Mircoli L, Giannattasio C, Mancia G, Ferrari AU. Effect of sympathectomy on mechanical properties of common carotid and femoral arteries. Hypertension 30: 1085-1088, 1997.
24. Meaume S, Benetos A, Henry OF, Rudnichi A, Safar ME. Aortic pulse wave velocity predicts cardiovascular mortality in subjects -70 years of age. Arterioscler Thromb Vasc Biol 21: 2046-2050, 2001.
25. Millasseau SC, Stewart AD, Patel SJ, Redwood SR, Chowienczyk PJ. Evaluation of carotid-femoral pulse wave velocity: influence of timing algorithm and heart rate. Hypertension 45: 222-226, 2005.
26. Mircoli L, Mangoni AA, Giannattasio C, Mancia G, Ferrari AU. Heart rate-dependent stiffening of large arteries in intact and sympathectomized rats. Hypertension 34: 598-602, 1999.
27. Mitchell GF, Hwang SJ, Vasan RS, Larson MG, Pencina MJ, Hamburg NM, Vita JA, Levy D, Benjamin EJ. Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation 121: 505-511, 2010.
28. Nichols W, O'Rourke M, Vlachopoulos C. McDonald's blood flow in arteries. Theoretical, experimental and clinical principles. 6th ed. New York: Oxford University Press, 2011.
29. Nurnberger J, Opazo Saez A, Dammer S, Mitchell A, Wenzel RR, Philipp T, Schafers RF. Left ventricular ejection time: a potential determinant of pulse wave velocity in young, healthy males. J Hypertens 21: 2125-2132, 2003.
30. O'Rourke MF, Mancia G. Arterial stiffness. J Hypertens 17: 1-4, 1999.
31. Othmane Tel H, Bakonyi G, Egresits J, Fekete BC, Fodor E, Jarai Z, Jekkel C, Nemcsik J, Szabo A, Szabo T, Kiss I, Tisler A. Effect of sevelamer on aortic pulse wave velocity in patients on hemodialysis: a prospective observational study. Hemodial Int 11, Suppl 3: S13-S21, 2007.
32. Reant P, Dijos M, Donal E, Mignot A, Ritter P, Bordachar P, Dos Santos P, Leclercq C, Roudaut R, Habib G, Lafitte S. Systolic time intervals as simple echocardiographic parameters of left ventricular sys-tolic performance: correlation with ejection fraction and longitudinal two-dimensional strain. Eur J Echocardiogr 11: 834-844, 2010.
33. Reusz GS, Cseprekal O, Temmar M, Kis E, Cherif AB, Thaleb A, Fekete A, Szabo AJ, Benetos A, Salvi P. Reference values of pulse wave velocity in healthy children and teenagers. Hypertension 56: 217-224, 2010.
34. Sa Cunha R, Pannier B, Benetos A, Siche JP, London GM, Mallion JM, Safar ME. Association between high heart rate and high arterial rigidity in normotensive and hypertensive subjects. J Hypertens 15: 1423-1430, 1997.
35. Salvi P. Pulse waves. How vascular hemodynamycs affects blood pressure. Milan: Springer, 2012.
36. Salvi P, Lio G, Labat C, Ricci E, Pannier B, Benetos A. Validation of a new non-invasive portable tonometer for determining arterial pressure wave and pulse wave velocity: the PulsePen device. J Hypertens 22: 2285-2293, 2004.
37. Salvi P, Magnani E, Valbusa F, Agnoletti D, Alecu C, Joly L, Benetos A. Comparative study of methodologies for pulse wave velocity estimation. J Hum Hypertens 22: 669-677, 2008.
38. Salvi P, Meriem C, Temmar M, Marino F, Sari-Ahmed M, Labat C, Alla F, Joly L, Safar ME, Benetos A. Association of current weight and birth weight with blood pressure levels in Saharan and European teenager populations. Am J Hypertens 23: 379-386, 2010.
39. Salvi P, Revera M, Joly L, Reusz G, Iaia M, Benkhedda S, Chibane A, Parati G, Benetos A, Temmar M. Role of birth weight and postnatal growth on pulse wave velocity in teenagers. J Adolesc Health 51: 373-379, 2012.
40. Salvi P, Ruffini R, Agnoletti D, Magnani E, Pagliarani G, Comandini G, Pratico A, Borghi C, Benetos A, Pazzi P. Increased arterial stiffness in nonalcoholic fatty liver disease: the Cardio-GOOSE study. J Hypertens 28: 1699-1707, 2010.
41. Sharman JE, Davies JE, Jenkins C, Marwick TH. Augmentation index, left ventricular contractility, and wave reflection. Hypertension 54: 1099-1105, 2009.
42. Tan I, Butlin M, Liu YY, Ng K, Avolio AP. Heart rate dependence of aortic pulse wave velocity at different arterial pressures in rats. Hypertension 60: 528-533, 2012.
43. Tomiyama H, Hashimoto H, Tanaka H, Matsumoto C, Odaira M, Yamada J, Yoshida M, Shiina K, Nagata M, Yamashina A. Synergistic relationship between changes in the pulse wave velocity and changes in the heart rate in middle-aged Japanese adults: a prospective study. J Hypertens 28: 687-694, 2010.
44. Valbusa F, Labat C, Salvi P, Vivian ME, Hanon O, Benetos A. Orthostatic hypotension in very old individuals living in nursing homes: the PARTAGE study. J Hypertens 30: 53-60, 2012.
45. Van Bortel LM, Laurent S, Boutouyrie P, Chowienczyk P, Cruickshank JK, De Backer T, Filipovsky J, Huybrechts S, Mattace-Raso FU, Protogerou AD, Schillaci G, Segers P, Vermeersch S, Weber T. Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity. J Hypertens 30: 445-448, 2012.
46. Van de Werf F, Piessens J, Kesteloot H, De Geest H. A comparison of systolic time intervals derived from the central aortic pressure and from the external carotid pulse tracing. Circulation 51: 310-316, 1975.
47. Weissler AM, Harris WS, Schoenfeld CD. Systolic time intervals in heart failure in man. Circulation 37: 149-159, 1968.