Prevalence of nasal carriage and diversity of Staphylococcus aureus among inpatients and hospital staff at Korle Bu Teaching Hospital, Ghana

Journal of Global Antimicrobial Resistance

Volumn 1, Issue 4, 2013, Pages 189-193

  Egyir, Beverly ^a,b,c   Guardabassi, Luca ^b   Nielsen, Søren Saxmose ^b   Larsen, Jesper ^a   Addo, Kennedy Kwasi ^c   Newman, Mercy Jemima ^d   Larsen, Anders Rhod ^a  

^a STATENS SERUM INSTITUT   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c University of Ghana   (Ghana)

^d UNIVERSITY OF GHANA   (Ghana)

Author keywords

Africa; Carriage; Hospital staff; MRSA; Patients; Staphylococcus aureus

Indexed keywords

BACTERIAL PROTEIN; CEFOXITIN; CEFTRIAXONE; CEFUROXIME; CLINDAMYCIN; CLOXACILLIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; LINEZOLID; MECV PROTEIN; METICILLIN; NORFLOXACIN; PENICILLIN DERIVATIVE; PSEUDOMONIC ACID; RIFAMPICIN; SPA PROTEIN; TEICOPLANIN; TETRACYCLINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM CULTURE; BACTERIUM ISOLATE; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; EPSILOMETER TEST; FEMALE; GENE EXPRESSION; GENETIC VARIABILITY; GHANA; HOSPITAL PATIENT; HOSPITAL PERSONNEL; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MULTIDRUG RESISTANCE; NOSE; NOSE SMEAR; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; SCREENING TEST; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; TEACHING HOSPITAL;

EID: 84890370814     PISSN: 22137165     EISSN: 22137173     Source Type: Journal    
DOI: 10.1016/j.jgar.2013.05.006     Document Type: Article

References (30)

1. H.F. Wertheim, D.C. Melle, M.C. Vos, W. van Leeuwen, A. van Belkum, and H.A. Verbrugh The role of nasal carriage in Staphylococcus aureus infections Lancet Infectious Diseases 5 2005 751 762 (Pubitemid 41688980)
2. S.M. Cavalcanti, E.R. Franca, C. Cabral, M.A. Vilela, F. Montenegro, and D. Menezes Prevalence of Staphylococcus aureus introduced into intensive care units of a university hospital Brazilian Journal of Infectious Diseases 9 2005 56 63 (Pubitemid 41686166)
3. C. von Eiff, K. Becker, K. Machka, H. Stammer, and G. Peters Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group New England Journal of Medicine 344 2001 11 16 (Pubitemid 32064839)
4. D.C. Melles, R.F. Gorkink, H.A. Boelens, S.V. Snijders, J.K. Peeters, and M.J. Moorhouse Natural population dynamics and expansion of pathogenic clones of Staphylococcus aureus Journal of Clinical Investigation 114 2004 1732 1740 (Pubitemid 40385529)
5. L.H. Hutzler, J.D. Slover, M. Phillips, and J.A. Bosco Staphylococcus aureus screening and decolonization and orthopaedic surgical site infection - a review of literature and single institution experience Journal of Orthopaedics 8 2011 e8
6. A.O.A. Ahmed, V.A. Belkum, A.H. Fahal, A.E.A. Elnor, E.S.A.M. Abougroun, and M.A.F.Q. Vandenbergh Surgical-site infections in a Sudanese university hospital Journal of Clinical Microbiology 36 1998 3614 3618
7. Y.A. Nur, M.F.Q. VandenBergh, M.A. Yusuf, A. van Belkum, and H.A. Verbrugh Nasal carriage of multiresistant Staphylococcus aureus among health care workers and pediatric patients in two hospitals in Mogadishu, Somalia International Journal of Infectious Diseases 1 1997 186 191 (Pubitemid 27255960)
8. A.N. Ulysse, F. Schaumburg, A.A. Adegnika, K. Kösters, T. Möller, and J.F. Fernandes Epidemiology and population structure of Staphylococcus aureus in various population groups from a rural and semi urban area in Gabon, Central Africa Acta Tropica 124 2012 42 47
9. S. Breurec, S.B. Zriouil, C. Fall, P. Boisier, S. Brisse, and S. Djibo Epidemiology of methicillin-resistant Staphylococcus aureus lineages in five major African towns: emergence and spread of atypical clones Clinical Microbiology and Infection 17 2010 160 165
10. B. Ghebremedhin, M.O. Olugbosi, A.M. Raji, F. Layer, R.A. Bakare, and B. Konig Emergence of a community-associated methicillin-resistant Staphylococcus aureus strain with a unique resistance profile in Southwest Nigeria Journal of Clinical Microbiology 47 2009 2975 2980
11. A.O. Shittu, K. Okon, S. Adesida, O. Oyedar, W. Witte, and B. Strommenger Antibiotic resistance and molecular epidemiology of Staphylococcus aureus in Nigeria BMC Microbiology 11 2011 92
12. D. Harmsen, H. Claus, W. Witte, J. Rothgänger, D. Turnwald, and U. Vogel Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management Journal of Clinical Microbiology 41 2003 5442 5448 (Pubitemid 37543228)
13. M.M. Fitzgibbon, A.S. Rossney, and B. O'Connell Investigation of reduced susceptibility to glycopeptides among methicillin-resistant Staphylococcus aureus isolates from patients in Ireland and evaluation of agar screening methods for detection of heterogeneously glycopeptide-intermediate S. aureus Journal of Clinical Microbiology 45 2007 3263 3269 (Pubitemid 47585649)
14. A.R. Larsen, M. Stegger, and M. Sørum spa typing directly from a mecA, spa and pvl multiplex PCR assay - a cost-effective improvement for methicillin-resistant Staphylococcus aureus surveillance Clinical Microbiology and Infection 14 2008 611 614 (Pubitemid 351639079)
15. M.C. Enright, N.P. Day, C.E. Davies, S.J. Peacock, and B.G. Spratt Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus Journal of Clinical Microbiology 38 2000 1008 1015 (Pubitemid 30140551)
16. Y. Kondo, T. Ito, X.X. Ma, S. Watanabe, B.N. Kreiswirth, and J. Etienne Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions Antimicrobial Agents and Chemotherapy 51 2007 264 274 (Pubitemid 46047716)
17. R Development Core Team R: a language and environment for statistical computing 2012 R Foundation for Statistical Computing Vienna, Austria http://www.R-project.org [accessed 18.06.13]
18. J. Kluytmans, V.A. Belkum, and H. Verbrugh Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks Clinical Microbiology Reviews 10 1997 505 520 (Pubitemid 27359263)
19. W.C. Albrich, and S. Harbarth Health-care workers: source, vector, or victim of MRSA? Lancet Infectious Diseases 8 2008 289 301 (Pubitemid 351615756)
20. A.O. Shittu, and J. Lin Antimicrobial susceptibility patterns and characterization of clinical isolates of Staphylococcus aureus in KwaZulu-Natal Province, South Africa BMC Infectious Diseases 6 2006 125
21. C.S. Zinn, H. Westh, V.T. Rosdahl SARISA Study Group An international multicenter study of antimicrobial resistance and typing of hospital Staphylococcus aureus isolates from 21 laboratories in 19 countries or states Microbial Drug Resistance 10 2004 160 168 (Pubitemid 38879017)
22. D.J. Farrell, M. Castanheira, and I. Chopra Characterization of global patterns and the genetics of fusidic acid resistance Clinical Infectious Diseases 52 Suppl. 7 2011 S487 S492
23. S. Breurec, C. Fall, R. Pouillot, P. Boisier, S. Brisse, and F. Diene-Sarr Epidemiology of methicillin-susceptible Staphylococcus aureus lineages in five major African towns: high prevalence of Panton-Valentine leukocidin genes Clinical Microbiology and Infection 17 2010 633 639
24. R.A. Ruimy, A. Maiga, L. Armand-Lefevre, I. Maiga, M.A. Diallo, and A.K. Koumaré The carriage population of Staphylococcus aureus from Mali is composed of a combination of pandemic clones and the divergent Panton-Valentine leukocidin-positive genotype ST152 Journal of Bacteriology 190 2008 3962 3968 (Pubitemid 351732876)
25. J.A. Otter, and G.L. French Molecular epidemiology of community-associated methicillin-resistant Staphylococcus aureus in Europe Lancet Infectious Diseases 10 2010 227 239
26. M. Aires-de-Sousa, B. Correia, and H. de Lencastre Changing patterns in frequency of recovery of five methicillin-resistant Staphylococcus aureus clones in Portuguese hospitals: surveillance over a 16-year period Journal of Clinical Microbiology 46 2008 2912 2917
27. H. Fang, G. Hedin, G. Li, and C.E. Nord Genetic diversity of community-associated methicillin-resistant Staphylococcus aureus in southern Stockholm, 2000-2005 Clinical Microbiology and Infection 14 2008 370 376 (Pubitemid 351356529)
28. F. Schaumburg, R. Köck, A.W. Friedrich, S. Soulanoudjingar, A.N. Ulysse, and C. von Eiff Population structure of Staphylococcus aureus from remote African Babongo Pygmies PLOS Neglected Tropical Diseases 5 2011 e1150
29. G.W. Coombs, S. Monecke, J.C. Pearson, T. Hui-leen, C. Yi-Kong, and L. Wilson Evolution and diversity of community-associated methicillin-resistant Staphylococcus aureus in a geographical region BMC Microbiology 11 2011 215
30. K.S. Ko, J.-Y. Lee, J.Y. Bek, K.R. Peck, J.Y. Rhee, and K.T. Kwon Characterization of Staphylococcus aureus nasal carriage from children attending an outpatient clinic in Seoul, Korea Microbial Drug Resistance 14 2008 37 44 (Pubitemid 351441846)